170 Efficacy Population Analysis 19-23 days protocol deviaition (chart) 26 Sep 2022 Final.xlsx

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	U	V	W	X	Z	AA	AB	AC	AD	AE	AF	AG	AH	AI	AJ	AK	AL	AM	AN	AO	AP	AQ	AR	AS	AT	AU	AV	AW	AX	AY	BA	BB	BC	BD	BE	BF	BG	BH	BI	BJ	BK	BL	BM	BN	BO	BP	BQ	BR	BS
1	SortOrder	Subject	(Country/Age in Years/Sex)	Abstractor Vaccination Date 01 VAX101DT	Abstractor Datetime of First Exposure to Treatment TRTSDTM	Abstractor Vaccination 01 VAX101	Abstractor Vaccination Date 02 VAX102DT	Abstractor Datetime of Last Exposure in Period 01 TR01EDTM	Abstractor Vaccination 02 VAX102	Vaccine Group (as Randomized)	Dose	Rel Day	Start Date of First Symptom	Stop Date of Last Symptom	Visit 1 N-Binding Assay/ Visit 1 NAAT/ Visit 2 NAAT	Visit 1 N-Binding Assay	Visit 1 NAAT	Visit 2 NAAT	Signs and Symptoms	SARS-CoV-2 NAAT Result (Central Lab/Local Labb)	SARS-CoV-2 NAAT Result (Central Lab)	SARS-CoV-2 NAAT Result (Local Labb)		Subject ID	Dose 1 Date	Dose 1 Day	Time of Day (24 hr)	Dose 2 Date	Dose 2 Day	Time of Day (24 hr)	Delta	Elapsed Days / Hrs	Narrative / Comments	#3 fa Interim Protocol Deviation Sensitive	#4 Interim mth6 Protocol Deviation	#5 fa Interim Excluded Patients	#6 Fa Interim Excluded Patients Sensitive	#7 Interim mth6 Excluded patients	#8 Interim mth6 Excluded Patientrs Sensitive	#9 fa Interim Dicontinued	#10 Interim mth6 Discontinued	Age	Sex	Ccountry	SubJid	Race	BMI kg/m2	Ethnicity	Age
2	1	C4591001 1003 10031122	(USA/48/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	77	11/5/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills	Pos/	Pos		#REF!	10031122	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Illness Visit 1 C-Neg/Local Neg; Illness Visit 2 C-Pos/L-Neg	No	No	No	No	No	No	No	No	48	M	USA	10031122	White	37.4	Non-Hispanic/non-Latino	48	Category	BNT162b2	Placebo	Total			16	17	18	19	20	21	22	23	24	25	26	27	28
3	6	C4591001 1006 10061012	(USA/53/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	68	11/6/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath New or increased muscle pain	Pos/	Pos		#REF!	10061012	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab positive/ Local lab SARS-CoV-2 NAAT not done	No	No	No	No	No	No	No	No	53	M	USA	10061012	White	33.9	Non-Hispanic/non-Latino	53		8	0	8	0	BNT162b2	0	0	0	0	0	0	0	0	0	0	0	0	0
4	12	C4591001 1006 10061066	(USA/39/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	59	11/11/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	10061066	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Protocol deviation: Dose 2 > 23 days post Dose 1	No	No	No	No	No	No	No	No	39	F	USA	10061066	White	26.5	Non-Hispanic/non-Latino	39					0	Placebo	0	0	0	0	0	0	0	0	0	0	0	0	0
5	15	C4591001 1006 10061084	(USA/27/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	48	10/27/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough	Pos/	Pos		#REF!	10061084	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab positive/ Local lab SARS-CoV-2 NAAT indeterminate.	No	No	No	No	No	No	No	No	27	F	USA	10061084	White	25.4	Non-Hispanic/non-Latino	27	16 to 55	5	0	5	0	BNT > 23	0	0	0	0	0	0	0	0	0	0	0	0	0
6	19	C4591001 1006 10061091	(USA/20/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	50	10/30/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	10061091	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive	No	No	No	No	No	No	No	No	20	F	USA	10061091	Asian	36.4	Non-Hispanic/non-Latino	20	>55 yr	3	0	3	0	Plac >23	0	0	0	0	0	0	0	0	0	0	0	0	0
7	22	C4591001 1006 10061114	(USA/21/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	35	10/20/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain New loss of taste or smell Sore throat	Pos/	Pos		#REF!	10061114	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive; urgent care visit (once)	No	No	No	No	No	No	No	No	21	M	USA	10061114	White	47.4	Hispanic/Latino	21	>=65 yr	1	0	1
8	29	C4591001 1008 10081011	(USA/55/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	52	10/22/2020	10/31/2020	Neg/Neg/Neg	Neg	Neg	Neg	New loss of taste or smell	Pos/	Pos		#REF!	10081011	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab positive/ Local lab SARS-CoV-2 NAAT not done	No	No	No	No	No	No	No	No	55	F	USA	10081011	White	25.2	Non-Hispanic/non-Latino	55	>=75 yr	0	0	0
9	31	C4591001 1008 10081048	(USA/38/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	60	11/7/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills New or increased muscle pain New loss of taste or smell Sore throat	Pos/	Pos		#REF!	10081048	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive; unspecified swab test done at [redacted] employee (once)	No	No	No	No	No	No	No	No	38	F	USA	10081048	White	57.3	Non-Hispanic/non-Latino	38
10	39	C4591001 1008 10081130	(USA/52/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	32	10/17/2020	10/29/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased shortness of breath	Pos/	Pos		#REF!	10081130	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive; visit ER (once) see narrative screen shot	No	No	No	No	No	No	No	No	52	F	USA	10081130	White	34.2	Non-Hispanic/non-Latino	52	Male	3	0	3
11	41	C4591001 1008 10081214	(USA/62/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	42	11/9/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased shortness of breath New or increased muscle pain	Pos/	Pos		#REF!	10081214	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive	No	No	No	No	No	No	No	No	62	M	USA	10081214	White	25.7	Non-Hispanic/non-Latino	62	Female	5	0	5
12	49	C4591001 1008 10081319	(USA/79/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	31	11/4/2020		Neg/Neg/Neg	Neg	Neg	Neg	Chills	Pos/	Pos		#REF!	10081319	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive; visit ER (once)	No	No	No	No	No	No	No	No	79	F	USA	10081319	White	24.1	Non-Hispanic/non-Latino	79
13	51	C4591001 1008 10081356	(USA/63/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	25	10/31/2020	11/10/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	10081356	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab positive/ Local lab SARS-CoV-2 NAAT not done	No	No	No	No	No	No	No	No	63	M	USA	10081356	White	27.4	Non-Hispanic/non-Latino	63	White	7	0	7
14	55	C4591001 1009 10091128	(USA/51/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	30	10/15/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills New or increased muscle pain New loss of taste or smell Sore throat	Pos/	Pos		#REF!	10091128	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab pos / Local lab posisitive	No	No	No	No	No	No	No	No	51	M	USA	10091128	White	37.6	Hispanic/Latino	51	Black	0	0	0
15	65	C4591001 1013 10131288	(USA/53/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	11	9/25/2020	10/6/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills New or increased muscle pain New loss of taste or smell	Pos/	Pos		#REF!	10131288	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local LabPos; urgent care visit	No	No	No	No	No	No	No	No	53	M	USA	10131288	White	31.1	Non-Hispanic/non-Latino	53	Others	1	0	1
16	74	C4591001 1013 10131475	(USA/49/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	23	10/22/2020	10/25/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10131475	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; went to govt test center once	No	No	No	No	No	No	No	No	49	F	USA	10131475	White	30.1	Non-Hispanic/non-Latino	49	Hispanic	3	0	3
17	79	C4591001 1016 10161003	(USA/23/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	57	10/14/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New loss of taste or smell	Pos/	Pos		#REF!	10161003	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local LabPos; went to children-adolescent's clinic once	No	No	No	No	No	No	No	No	23	F	USA	10161003	White	22.1	Non-Hispanic/non-Latino	23	Non-Hispanic	5	0	5
18	86	C4591001 1016 10161004	(USA/51/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	BNT162b2 (30 μg)	Dose 2	58	10/15/2020	10/22/2020	Neg/Neg/Neg	Neg	Neg	Neg	New loss of taste or smell Sore throat	Pos/	Pos		#REF!	10161004	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	1003 and 1004 dose 1 one min apart; Central lab Pos; Local Lab Pos/Neg	No	No	No	No	No	No	No	No	51	F	USA	10161004	White	24.2	Non-Hispanic/non-Latino	51
19	89	C4591001 1016 10161017	(USA/18/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	19	9/7/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills New or increased muscle pain New loss of taste or smell	Pos/	Pos		#REF!	10161017	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; urgent care visit (once)	No	No	No	No	No	No	No	No	18	F	USA	10161017	White	24.2	Non-Hispanic/non-Latino	18	Argentina	1	0	1
20	96	C4591001 1016 10161035	(USA/70/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	67	10/29/2020	10/29/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	10161035	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; urgent care visit (once)	No	No	No	No	No	No	No	No	70	F	USA	10161035	White	23.9	Non-Hispanic/non-Latino	70	Brazil	1	0	1
21	98	C4591001 1016 10161048	(USA/52/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	75	11/6/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10161048	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; used drive-throu clinic (once)	No	No	No	No	No	No	No	No	52	F	USA	10161048	White	33.7	Non-Hispanic/non-Latino	52	USA	6	0	6
22	103	C4591001 1016 10161183	(USA/31/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	32	10/16/2020	11/1/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain New loss of taste or smell Sore throat Diarrhea Vomiting	Pos/ (R1 Pos)	Pos	(R1 Pos)	#REF!	10161183	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; urgent care visit (once)	No	No	No	No	No	No	No	No	31	F	USA	10161183	White	36.1	Non-Hispanic/non-Latino	31		8	0	8
23	115	C4591001 1016 10161207	(USA/62/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	27	10/14/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10161207	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos; subject went to her primary care (physician once)	No	No	No	No	No	No	No	No	62	F	USA	10161207	White	37.4	Non-Hispanic/non-Latino	62
24	121	C4591001 1018 10181198	(USA/50/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	55	11/4/2020	11/5/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough	Pos/	Pos		#REF!	10181198	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab was not done	No	No	No	No	No	No	No	No	50	F	USA	10181198	White	28.4	Non-Hispanic/non-Latino	50
25	125	C4591001 1019 10191038	(USA/47/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	61	11/3/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	10191038	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	47	F	USA	10191038	White	32.5	Hispanic/Latino	47	Others	BNT162b2	Placebo	Total
26	131	C4591001 1019 10191184	(USA/52/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	36	11/5/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain Vomiting	Pos/	Pos		#REF!	10191184	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	52	M	USA	10191184	White	38.0	Non-Hispanic/non-Latino	52	Asian	1	0	1
27	136	C4591001 1028 10281038	(USA/53/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	31	10/10/2020	10/22/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Sore throat	Pos/	Pos		#REF!	10281038	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Cental Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	53	F	USA	10281038	White	49.0	Non-Hispanic/non-Latino	53	Not Reported	0	0	0
28	141	C4591001 1028 10281100	(USA/47/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	19	10/11/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	10281100	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	47	F	USA	10281100	White	23.6	Non-Hispanic/non-Latino	47	American Indian or Alaska Native	0	0	0
29	143	C4591001 1028 10281132	(USA/61/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	14	10/11/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10281132	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	61	M	USA	10281132	White	26.2	Non-Hispanic/non-Latino	61	Native Hawaiian or Other Pacific Islander	0	0	0
30	151	C4591001 1028 10281138	(USA/38/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	25	10/23/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills Sore throat Diarrhea	Pos/	Pos		#REF!	10281138	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Influenza vax 21 Oct 2020; Visit Illness 1 Central Lab Neg/Local Lab Neg; Visit 2 C-Pos/L-Neg, L-Pos	No	No	No	No	No	No	No	No	38	F	USA	10281138	White	27.2	Non-Hispanic/non-Latino	38	Multiple	0	0	0
31	156	C4591001 1037 10371036	(USA/62/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	52	10/31/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills	Pos/	Pos		#REF!	10371036	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	62	M	USA	10371036	Black or African American	27.2	Non-Hispanic/non-Latino	62	Total	1	0	1
32	161	C4591001 1037 10371280	(USA/58/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	28	11/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain	Pos/	Pos		#REF!	10371280	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	58	M	USA	10371280	White	39.2	Non-Hispanic/non-Latino	58
33	168	C4591001 1038 10381051	(USA/69/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	51	11/7/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	10381051	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	69	M	USA	10381051	White	36.3	Non-Hispanic/non-Latino	69	Obese	BNT162b2	Placebo	Total
34	171	C4591001 1039 10391025	(USA/55/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	40	10/25/2020	11/3/2020	Neg/Neg/Neg	Neg	Neg	Neg	New loss of taste or smell Sore throat	Pos/	Pos		#REF!	10391025	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	55	F	USA	10391025	White	21.9	Non-Hispanic/non-Latino	55	Yes	3	0	3
35	174	C4591001 1046 10461058	(USA/44/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	62	11/9/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased muscle pain	Pos/	Pos		#REF!	10461058	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab SARS-CoV-2 NAAT was not done.	No	No	No	No	No	No	No	No	44	F	USA	10461058	White	30.1	Non-Hispanic/non-Latino	44	No	5	0	5
36	176	C4591001 1047 10471024	(USA/63/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	BNT162b2 (30 μg)	Dose 2	37	10/16/2020	10/18/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever Diarrhea Vomiting	Pos/	Pos		#REF!	10471024	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos; urgent care visit (once)	No	No	No	No	No	No	No	No	63	F	USA	10471024	White	38.2	Non-Hispanic/non-Latino	63		8	0	8
37	180	C4591001 1068 10681082	(USA/58/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	42	11/1/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased shortness of breath Sore throat	Pos/	Pos		#REF!	10681082	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos/L-pos; #4 16.2.2 Protocol deviations and #3 16.2.23 Important Protocol Deviations	Yes	Yes	No	No	No	No	No	No	58	M	USA	10681082	White	28.2	Non-Hispanic/non-Latino	58	Age group (years) and obese
38	187	C4591001 1068 10681110	(USA/30/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	22	10/16/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	10681110	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos; urgent care visit (once)	No	No	No	No	No	No	No	No	30	F	USA	10681110	White	35.3	Non-Hispanic/non-Latino	30	16-64 not obese	4	0	4
39	191	C4591001 1071 10711022	(USA/47/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	72	11/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10711022	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab SARS-CoV-2 NAAT was not done.	No	No	No	No	No	No	No	No	47	M	USA	10711022	Multiple	43.0	Non-Hispanic/non-Latino	47	16-64 and obese	3	0	3
40	197	C4591001 1071 10711058	(USA/72/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	60	11/6/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	10711058	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos; Local Lab Pos	No	No	No	No	No	No	No	No	72	F	USA	10711058	White	35.9	Non-Hispanic/non-Latino	72	>=65 not obese	1	0	1
41	200	C4591001 1072 10721057	(USA/70/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	41	10/26/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	10721057	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab pos; unblinded received BNT162b22 26Feb2021	No	No	No	No	No	No	No	No	70	M	USA	10721057	White	31.6	Non-Hispanic/non-Latino	70	>=65 and obese	0	0	0
42	202	C4591001 1077 10771195	(USA/73/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	40	11/1/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased muscle pain	Pos/	Pos		#REF!	10771195	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab pos; unblinded BNT162b22 01Jan2021 & 11Feb2021	No	No	No	No	No	No	No	No	73	F	USA	10771195	White	24.6	Non-Hispanic/non-Latino	73	Total	8	0	8
43	208	C4591001 1079 10791046	(USA/55/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	62	10/26/2020		Neg/Neg/Neg	Neg	Neg	Neg	New loss of taste or smell	Pos/	Pos		#REF!	10791046	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab pos; unblinded BNT162b22 16Feb2021 & 12Mar2021	No	No	No	No	No	No	No	No	55	F	USA	10791046	White	35.6	Non-Hispanic/non-Latino	55
44	210	C4591001 1079 10791054	(USA/28/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	63	10/29/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	10791054	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab pos / Local Neg, Pos; unblinded BNT162b2 22Dec2020 & 13Jan2021	No	No	No	No	No	No	No	No	28	F	USA	10791054	White	33.5	Non-Hispanic/non-Latino	28
45	212	C4591001 1081 10811151	(USA/79/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	10	9/30/2020	10/14/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	10811151	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab not done; unblinded BNT162b2 26Jan2021 & 22Feb2021	No	No	No	No	No	No	No	No	79	F	USA	10811151	White	37.4	Non-Hispanic/non-Latino	79
46	214	C4591001 1082 10821016	(USA/46/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	44	10/6/2020	10/27/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain New loss of taste or smell	Pos/	Pos		#REF!	10821016	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab pos; unblinded BNT162b2 22Dec2020 & 12Jan2021	No	No	No	No	No	No	No	No	46	F	USA	10821016	White	29.2	Non-Hispanic/non-Latino	46
47	223	C4591001 1085 10851293	(USA/63/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	37	11/7/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	10851293	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab not done; unblinded BNT162b2 13Jan2021 & 03Feb2021	No	No	No	No	No	No	No	No	63	F	USA	10851293	Asian	27.3	Non-Hispanic/non-Latino	63
48	229	C4591001 1088 10881219	(USA/63/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	17	10/25/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased muscle pain	Pos/	Pos		#REF!	10881219	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Control lab pos / Local lab pos; unblinded BNT162b2 22Dec2020 & 13Jan2021	No	No	No	No	No	No	No	No	63	M	USA	10881219	White	28.0	Non-Hispanic/non-Latino	63
49	235	C4591001 1088 10881233	(USA/47/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	15	11/2/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills Sore throat	Pos/	Pos		#REF!	10881233	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Protocol deviation: Dose 2 > 23 days post Dose 1	No	No	No	No	No	No	No	No	47	M	USA	10881233	Native Hawaiian or Other Pacific Islander	26.5	Non-Hispanic/non-Latino	47
50	241	C4591001 1089 10891235	(USA/29/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	47	11/8/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	10891235	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab posisitive / Local Lab positive; unblinded BNT162b2 12Feb, 9Mar2021	No	No	No	No	No	No	No	No	29	F	USA	10891235	Black or African American	33.3	Non-Hispanic/non-Latino	29
51	244	C4591001 1090 10901121	(USA/58/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	49	10/18/2020	10/22/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New loss of taste or smell	Pos/	Pos		#REF!	10901121	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab posisitive / Local Lab positive; withdrawal by subject 16 Dec 2020	No	No	No	No	No	No	No	Yes	58	F	USA	10901121	White	30.6	Non-Hispanic/non-Latino	58
52	248	C4591001 1090 10901353	(USA/63/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	40	11/8/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough	Pos/	Pos		#REF!	10901353	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Illness Visit 1 Central lab pos / Local lab Pos: unblinded received BNT162b2 01Mar2021	No	No	No	No	No	No	No	No	63	M	USA	10901353	White	28.7	Non-Hispanic/non-Latino	63
53	252	C4591001 1091 10911203	(USA/43/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	44	11/5/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased Unk/Pos cough New or increased muscle pain				#REF!	10911203	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab: No SARS-CoV-2 Test / Local lab positive (71); primary care physician (once)	No	No	No	No	No	No	No	No	43	M	USA	10911203	White	33.9	Non-Hispanic/non-Latino	43
54	256	C4591001 1092 10921021	(USA/60/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	48	10/27/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain	Pos/	Pos		#REF!	10921021	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab not done	No	No	No	No	No	No	No	No	60	F	USA	10921021	White	26.2	Non-Hispanic/non-Latino	60
55	263	C4591001 1092 10921130	(USA/53/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	18	10/9/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased shortness of breath New loss of taste or smell Sore throat Diarrhea	Pos/	Pos		#REF!	10921130	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	16.2.1.4 - Listing of Subjects Withdrawn From the Study 12 Oct 2020*	No	No	No	No	No	No	Yes	No	53	M	USA	10921130	White	31.3	Non-Hispanic/non-Latino	53
56	273	C4591001 1093 10931081	(USA/67/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	19	10/5/2020	10/19/2020	Neg/Neg/Neg	Neg	Neg	Neg	Sore throat	Pos/	Pos		#REF!	10931081	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab not done	No	No	No	No	No	No	No	No	67	F	USA	10931081	White	25.7	Non-Hispanic/non-Latino	67
57	275	C4591001 1095 10951238	(USA/63/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	19	11/2/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills New or increased muscle pain Sore throat Diarrhea	Pos/	Pos		#REF!	10951238	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	63	F	USA	10951238	White	29.0	Hispanic/Latino	63
58	284	C4591001 1095 10951260	(USA/25/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	9	11/5/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills New or increased muscle pain Sore throat	Pos/	Pos		#REF!	10951260	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	25	M	USA	10951260	White	27.9	Hispanic/Latino	25
59	290	C4591001 1096 10961172	(USA/51/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	49	11/6/2020	11/8/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough	Pos/	Pos		#REF!	10961172	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	51	M	USA	10961172	White	23.7	Non-Hispanic/non-Latino	51
60	294	C4591001 1096 10961258	(USA/55/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	25	10/22/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain Sore throat	Pos/Pos	Pos	Pos	#REF!	10961258	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos; Protocol deviation: Dose 2 > 23 days post Dose 1	No	No	No	No	No	No	No	No	55	F	USA	10961258	White	21.8	Non-Hispanic/non-Latino	55
61	299	C4591001 1098 10981062	(USA/63/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	32	10/17/2020	10/20/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased muscle pain	Pos/	Pos		#REF!	10981062	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab not done	No	No	No	No	No	No	No	No	63	F	USA	10981062	Black or African American	29.2	Non-Hispanic/non-Latino	63
62	301	C4591001 1101 11011095	(USA/60/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	20	11/2/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	11011095	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	60	M	USA	11011095	White	27.5	Non-Hispanic/non-Latino	60
63	303	C4591001 1107 11071171	(USA/39/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	58	11/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills	Pos/	Pos		#REF!	11071171	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	39	M	USA	11071171	White	36.3	Non-Hispanic/non-Latino	39
64	306	C4591001 1109 11091067	(USA/42/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	84	11/11/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased shortness of breath Sore throat	Pos/	Pos		#REF!	11091067	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab not done	No	No	No	No	No	No	No	No	42	M	USA	11091067	White	28.8	Non-Hispanic/non-Latino	42
65	309	C4591001 1109 11091092	(USA/18/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	70	10/31/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Sore throat	Pos/	Pos		#REF!	11091092	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab Pos	No	No	No	No	No	No	No	No	18	M	USA	11091092	White	19.1	Non-Hispanic/non-Latino	18
66	314	C4591001 1109 11091323	(USA/64/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	47	10/31/2020	11/2/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain	Pos/	Pos		#REF!	11091323	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos; Local Lab not done	No	No	No	No	No	No	No	No	64	M	USA	11091323	White	28.5	Non-Hispanic/non-Latino	64
67	321	C4591001 1109 11091416	(USA/46/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	41	11/3/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Sore throat	Pos/	Pos		#REF!	11091416	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central lab positive / Local lab SARS-CoV-2 not done.	No	No	No	No	No	No	No	No	46	F	USA	11091416	White	36.8	Non-Hispanic/non-Latino	46
68	326	C4591001 1109 11091448	(USA/46/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	9	10/6/2020	10/28/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased shortness of breath New or increased muscle pain Sore throat	Pos/ (R1 Pos)	Pos	(R1 Pos)	#REF!	11091448	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Serious AE Hemiplegic migraine Grade 4; Covid ilness visit 1 (9) C- two Pos, L-Pos	No	No	No	No	No	No	No	No	46	F	USA	11091448	White	29.4	Non-Hispanic/non-Latino	46
69	335	C4591001 1109 11091482	(USA/63/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	28	10/29/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	11091482	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1, Central lab pos (55) / Local lab Neg (55)	No	No	No	No	No	No	No	No	63	M	USA	11091482	White	25.8	Non-Hispanic/non-Latino	63
70	339	C4591001 1110 11101050	(USA/47/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	BNT162b2 (30 μg)	Dose 2	76	11/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills Sore throat	Pos/	Pos		#REF!	11101050	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (98) /L-pos (98)	No	No	No	No	No	No	No	No	47	M	USA	11101050	White	24.4	Non-Hispanic/non-Latino	47
71	343	C4591001 1110 11101136	(USA/62/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	52	11/4/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills Diarrhea	Pos/	Pos		#REF!	11101136	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (59) /L-pos (73)	No	No	No	No	No	No	No	No	62	M	USA	11101136	White	37.8	Hispanic/Latino	62
72	347	C4591001 1110 11101162	(USA/51/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	BNT162b2 (30 μg)	Dose 2	34	10/24/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New loss of taste or smell	Pos/	Pos		#REF!	11101162	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (57) /L-pos (73)	No	No	No	No	No	No	No	No	51	M	USA	11101162	White	40.3	Hispanic/Latino	51
73	351	C4591001 1111 11111010	(USA/75/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	45	10/4/2020	10/5/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills	Pos/	Pos		#REF!	11111010	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (68) /Local lab SARS-CoV-2 test was not done	No	No	No	No	No	No	No	No	75	M	USA	11111010	White	29.3	Non-Hispanic/non-Latino	75
74	354	C4591001 1116 11161075	(USA/73/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	43	11/3/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills	Pos/	Pos		#REF!	11161075	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (66) /Local lab SARS-CoV-2 test was not done	No	No	No	No	No	No	No	No	73	M	USA	11161075	White	31.2	Non-Hispanic/non-Latino	73
75	359	C4591001 1117 11171010	(USA/72/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	34	10/11/2020	10/19/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough	Pos/	Pos		#REF!	11171010	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (56) /Local lab SARS-CoV-2 NAAT test was not done	No	No	No	No	No	No	No	No	72	F	USA	11171010	White	29.7	Non-Hispanic/non-Latino	72
76	363	C4591001 1118 11181088	(USA/73/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	36	10/20/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain	Pos/	Pos		#REF!	11181088	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (64) /L-pos (63); subject visited health dept nurse (once)	No	No	No	No	No	No	No	No	73	M	USA	11181088	White	28.4	Non-Hispanic/non-Latino	73
77	367	C4591001 1120 11201115	(USA/19/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	73	11/6/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased muscle pain Sore throat Diarrhea	Pos/	Pos		#REF!	11201115	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (95) /Local lab SARS-CoV-2 NAAT test was not done	No	No	No	No	No	No	No	No	19	F	USA	11201115	White	40.7	Non-Hispanic/non-Latino	19
78	373	C4591001 1122 11221025	(USA/40/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	32	11/1/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain	Pos/	Pos		#REF!	11221025	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid Ilness visit 1, C-pos (55) /L-pos (55); phone consultation and health clinic (once)	No	No	No	No	No	No	No	No	40	M	USA	11221025	White	28.4	Non-Hispanic/non-Latino	40
79	380	C4591001 1123 11231073	(USA/25/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	10	9/10/2020	10/6/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Chills New or increased muscle pain Sore throat	Pos/Pos	Pos	Pos	#REF!	11231073	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	COIVID Illness visit 1 10 Sep (Rel 10); C-Pos / L-Pos 11 Sep 2020: primary care physician (once)	No	No	No	No	No	No	No	No	25	F	USA	11231073	White	23.9	Non-Hispanic/non-Latino	25
80	386	C4591001 1123 11231086	(USA/35/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	57	10/27/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased muscle pain	Pos/	Pos		#REF!	11231086	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos	No	No	No	No	No	No	No	No	35	F	USA	11231086	White	22.4	Non-Hispanic/non-Latino	35
81	390	C4591001 1123 11231117	(USA/55/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	64	11/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	Chills New or increased muscle pain	Pos/	Pos		#REF!	11231117	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	55	F	USA	11231117	White	24.0	Non-Hispanic/non-Latino	55
82	394	C4591001 1123 11231214	(USA/60/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	34	10/26/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills New loss of taste or smell Sore throat	Pos/	Pos		#REF!	11231214	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos; Discontinued from Study 05 Feb 2021	No	No	No	No	No	No	No	Yes	60	F	USA	11231214	White	23.7	Non-Hispanic/non-Latino	60
83	402	C4591001 1123 11231255	(USA/76/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	20	10/24/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	11231255	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos	No	No	No	No	No	No	No	No	76	M	USA	11231255	White	24.3	Non-Hispanic/non-Latino	76
84	404	C4591001 1123 11231256	(USA/72/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	24	10/28/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	11231256	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	72	F	USA	11231256	White	25.2	Non-Hispanic/non-Latino	72
85	406	C4591001 1123 11231284	(USA/67/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	12	10/24/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills New or increased muscle pain	Pos/	Pos		#REF!	11231284	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos	No	No	No	No	No	No	No	No	67	M	USA	11231284	White	24.1	Non-Hispanic/non-Latino	67
86	413	C4591001 1125 11251006	(USA/35/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	42	10/11/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough Chills	Pos/	Pos		#REF!	11251006	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos	No	No	No	No	No	No	No	No	35	M	USA	11251006	White	30.5	Non-Hispanic/non-Latino	35
87	418	C4591001 1125 11251014	(USA/45/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	59	10/30/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased cough New or increased shortness of breath Chills New or increased muscle pain Diarrhea	Pos/	Pos		#REF!	11251014	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	45	F	USA	11251014	White	38.1	Non-Hispanic/non-Latino	45
88	428	C4591001 1125 11251023	(USA/49/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	56	10/27/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath Chills New or increased muscle pain	Pos/	Pos		#REF!	11251023	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	49	M	USA	11251023	White	33.0	Non-Hispanic/non-Latino	49
89	435	C4591001 1125 11251028	(USA/39/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	27	9/29/2020	10/2/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills New or increased muscle pain Sore throat	Pos/	Pos		#REF!	11251028	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	39	F	USA	11251028	White	31.3	Non-Hispanic/non-Latino	39
90	441	C4591001 1125 11251049	(USA/52/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	50	10/27/2020		Neg/Neg/Neg	Neg	Neg	Neg	New loss of taste or smell Sore throat	Pos/	Pos		#REF!	11251049	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	52	M	USA	11251049	White	32.6	Non-Hispanic/non-Latino	52
91	444	C4591001 1125 11251109	(USA/46/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	51	11/4/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased shortness of breath New or increased muscle pain Diarrhea	Pos/	Pos		#REF!	11251109	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local not done	No	No	No	No	No	No	No	No	46	F	USA	11251109	White	56.1	Hispanic/Latino	46
92	451	C4591001 1125 11251114	(USA/59/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	38	10/22/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever	Pos/Pos	Pos	Pos	#REF!	11251114	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Central Lab Pos, Local Pos	No	No	No	No	No	No	No	No	59	M	USA	11251114	White	31.5	Non-Hispanic/non-Latino	59
93	453	C4591001 1125 11251124	(USA/39/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	53	11/8/2020	11/10/2020	Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills New or increased muscle pain	Pos/	Pos		#REF!	11251124	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab SARS-CoV-2 not done.	No	No	No	No	No	No	No	No	39	M	USA	11251124	White	23.7	Non-Hispanic/non-Latino	39
94	458	C4591001 1125 11251215	(USA/43/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	25	11/6/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough	Pos/	Pos		#REF!	11251215	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab SARS-CoV-2 not done.	No	No	No	No	No	No	No	No	43	M	USA	11251215	White	35.7	Non-Hispanic/non-Latino	43
95	460	C4591001 1126 11261017	(USA/34/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	50	10/20/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever New or increased muscle pain	Pos/	Pos		#REF!	11261017	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	AE Acute sinusitis (3); 16.2.1.1 Withdrawal from study 28 Jan 2021; AE allergy to vaccine	No	No	No	No	No	No	No	Yes	34	F	USA	11261017	White	22.5	Non-Hispanic/non-Latino	34
96	464	C4591001 1128 11281165	(USA/26/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	46	10/29/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	11281165	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab positive; subject urgent care visit (once).	No	No	No	No	No	No	No	No	26	F	USA	11281165	White	21.1	Non-Hispanic/non-Latino	26
97	467	C4591001 1131 11311100	(USA/64/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	58	11/12/2020		Neg/Neg/Neg	Neg	Neg	Neg	Fever Chills New or increased muscle pain New loss of taste or smell	Pos/	Pos		#REF!	11311100	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab indertiminate; urgent care visit (once)	No	No	No	No	No	No	No	No	64	M	USA	11311100	White	32.1	Non-Hispanic/non-Latino	64
98	474	C4591001 1131 11311138	(USA/45/F)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	45	11/7/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough New or increased shortness of breath	Pos/	Pos		#REF!	11311138	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab SARS-CoV-2 not done.	No	No	No	No	No	No	No	No	45	F	USA	11311138	White	22.4	Non-Hispanic/non-Latino	45
99	478	C4591001 1133 11331209	(USA/30/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	32	10/10/2020		Neg/Neg/Neg	Neg	Neg	Neg	New or increased cough Sore throat	Pos/	Pos		#REF!	11331209	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	C-pos / Local lab SARS-CoV-2 not done; 16.2.1.1 Withdrawal from study 26 Feb 2021 Lost to follow up - certified letter sent 19 Feb 2021	No	No	No	No	No	No	No	Yes	30	M	USA	11331209	Black or African American	25.4	Hispanic/Latino	30
100	481	C4591001 1134 11341022	(USA/66/M)	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Placebo	Dose 2	29	9/29/2020	10/3/2020	Neg/Neg/Neg	Neg	Neg	Neg	New or increased muscle pain Sore throat	Pos/	Pos		#REF!	11341022	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	#REF!	Covid illness visit 1 Central Lab pos / Local lab SARS-CoV-2 not done.	No	No	No	No	No	No	No	No	66	M	USA	11341022	White	31.3	Non-Hispanic/non-Latino	66