9-ME-BC Effects/Side Effects/Interactions

Time till effect

5 weeks of continued compounding effects. 6 weeks total.

Heavy duty Drug damage/Suicidal

Heart palpitations during alchohol use. Migraines during Marijuana Usage.

Dopamine sensitivity restored, partial pleasure recovery.

Partial remission. Several Anhedonic symptoms remained possibly due to damage to separate brain systems. Used under supervision of a psychiatrist.

8 weeks of use. Effects stopped compounding at 7 1/2 weeks.

N/A Very High dopamine sensitivity, increased orgasm strength, mild hyperactivity.

2 weeks of use. Effects stopped improving at 1 1/2 weeks.

Noopept, Micro-dosed Psylociliban.

Erratic, Patient refused to take consistently and kept saying saftey concerns, Patient reported no benefit.

N/A Patient seemed erratic likely from hallucinogen intake. Was advised substance appears to work only when taken consistently. Advice ignored.

Adderall XR 20 mg, Straterra 70 mg.

"Honeymoon Period" restored after discontinuation. Patient reported that with concurrent Agmatine Sulfide use "Honeymoon period" has remained well after 2 months. Executive Function improvement.

Dampening of stimulant effect while in concurrent use, no interactions noted with NRI (Straterra) . Beyond dampening of stimulant effect no other interactions were noted. (Likely due to Tyrosine competition) Based on the time to take effect concurrent stimulant use likely slows down its effects.

N/A Patient reports receiving exactly what they were looking for and greatly enjoys restored hyperactive state. Also reports extreme increase in orgasm strength.

Concerta 18 mg, Intuniv 4 mg, Bromantane.

Restored Stimulant effect, anhedonia symptom remission.

None, stimulant dampening effect mentioned in adderall use not mentioned for concerta only effect intensification.

Full Remission Patient reports stimulant effects restored to baseline and depressive symptoms reduced.

Polygala, Lions Mane, Patient admits to binging alchohol when prodded.

Heart palpitations during alchohol use. Reports going to hospital during episode.

Partial Remission, Patient lost to follow up. Was advised to seek medical treatment for Alchohol Use and patient responded with hostility and vitriol.

Patient under care of physician reported increasing but competing symptom relief.

Unknown, Patient and care physician unable to differentiate between symptoms from other medicines and malady. Headaches, spasms, and light sensitivity mentioned.

Concerta 54 mg, Adderall XR 10 mg, Oxytocin 24 Iu's

Simultaneous dampaning and strengthening of stimulants. Patient Reports greatly improved executive function but diminished focus while in concurrant use. Matches earlier observation of Concerta and Adderall respectively. Occasional Priapism and hypersexuality. (Asperger diagnosis confounds this observation as does stimulant use.)

When taken seperately patient reports concerta effects massively improved, with patient reporting near constant levels of euphoria that remain (while in use) 3 months post 9-me-bc. Adderall improved in effect but tapered off to just above baseline. Patient mentions extreme increase in orgasm intensity, and sudden onset of frequent wet dreams. "It's like I am 12 again!" is a direct quote. Seems to indicate sexually positive interactions with oxytocin and stimulant use.

Repaired drug damage and allowed feeling of pleasure in everyday life. However no effects were noted on depression symptoms.

Partial remission of symptoms. Concurrent depression diagnosis limits potential gains due to SSRI use.

Patient under care of physician reported symptom improvement.

Sunburn, as with previous parkinson patient difficulty was had in determining source of symptoms. Patient did report fewer tremors.

Patient reports taking a break at doctors direction to perform blood work and tests but will continue use.

Patient reported stimulant sensitivity greatly increased and reported improvement in pleasure activities.

Remission of physical symptoms. Patient undergoing therapy at present for psychological symptoms.

8 weeks. Patient in rehab will take substance again under care of physician.

Patient reported increased Hyperactivity and ability to get out of bed and do things. Depressive symptoms partially abated, continuing treatment.

Partial remission of symptoms. Ability to Orgasm improved and sped up. (40+ minutes reduced to 10) (Straterra makes it difficult if not impossible to orgasm)

Patient under care of psychiatrist and taking under supervision. 4 weeks of use.

Patient reports increased executive function and ability to get out of bed, but reports no effect on focus.

Decreased physical symptoms of Parkinsons. Increased movement and mobility.

None according to physician. Standard side effects of L-Dopa reported.

Abatement of physical symptoms, patient indicates improved function and ability to resume normal life inconjunction with medications. Patient continuing to undergo supervised medical care.

7 weeks. Patient discontinued at urging of care physician, due to symptom amelioration. (This is really odd to me and him as well as Parkinsons is degenerative by definition the improvements will likely degenerate. Patient indicates they will continue taking with or without physician if symptoms return to previous levels.)

Noopept, Huperzine-A, Caffeine, Nicotine (Patch)

No improvements reported: See side effects. (Patient likely a non-responder as they report not responding to most cognitive enhancing substances with those mentioned in concurrent substances as exceptions.)

Patient mentioned extreme migraines in first week of use, that abated when she ceased taking Nicotine. Patient discontinued Nicotine for duration of use. No further side effects were reported. Simultaneously no beneficial effects were reported either. (Nicotine may have confounded the possible effects due to extreme reaction. Similar lesser reactions reported in 3 other patients.)

Patient reports no increase in stimulant sensitivity at the end of 8 weeks and discontinued use. Patient resumed use of Nicotine Patch. Also reports no wakefulness enhancing effects from Caffeine both before and after use.

Modafinil, Mr. Happy Stack, Vegan Diet (was mentioned)

Greatly increased stimulant sensitivity and sudden onset of beneficial hyperactivity. "I am bouncing off the walls like my 8 year old!" is a direct quote.

Premature ejaculation. (From five minutes to sub 1 minute) No other side effects reported.

Patient reports large increase in productivity and desired effects. Has mixed feeling on onset of premature ejaculation which has remained post cessation of substance. Onset of hyperactivity has remained 2 months post cessation and patient indicates he greatly enjoys it.

Daytrana 30 mg, Clonidine, Oxytocin, Vasopressin (Bed Wetting)

Improved methyphenidate effect, increased executive function, increased focus, increased orgasm strength, non prescribed stimulant hypersensitivity. "I cannot have coffee anymore." Direct Quote.

Premature Ejaculation Onset reported (3 minutes to sub 20 seconds), refractory period seemingly eliminated, increased frequency of wet dreams. No other side effects reported.

Patient has enjoyed an increase in the effectiveness of his prescribed medication and tells me since he is not sexually active he greatly enjoys the side effects. (By this point I was beginning to notice a distinct pattern with ADHD sufferers and interactions with prescribed medication and oxytocin.)

8 weeks. Patient has reported effects have remained 3 months post cessation of use and has promised to contact me if the results ever start to go away.

Decrease in Psychotic behaviours, increased stimulant effect post cessation, extreme non prescribed stimulant hypersenitivity, partial restoration of sex drive.

Stimulant Blunting while in effect, mild increase in insomnia. (Already present from anti-psychotic.)

Patient describes decrease in symptom severity, and increase in stimulant effectiveness 2 months post cessation. "I got what I wanted." Direct quote. Patient also reports increase in sex drive which has been non-existent since beginning anti-psychotic.

Increased emotional range, no increase in pleasurable sensations.

Patient describes increase of emotional range unrelated to NSI-189 and IDRA-21. As these compounds also increase emotional intensity this makes parsing whether he responded or not difficult. Patient also reports over responsiveness to caffeine.

None reported, (Heroin post cessation.)

Patient advised to go to rehab first, responded with flippancy. Reports "I can feel good again!".

Patient exhibited extreme drug seeking tendencies, and came off as a total junkie that just wanted another fix. Patient supposedly got her second chance but immediately blew it and tried to blame me. User was blocked and I made the decision not to take anymore people with severe drug use.

4 weeks. Patient relapsed and undid all previously gained sensitivity. Patient blocked pending self inflicted relapse and lashing out.

*Smoker (Nicotine), Huperzine-A, Ginko Biloba

Patient reports increased hyperactivity and stimulant sensitivity.

Patient was pleasant and described getting exactly what she wanted out of the experience.

C-dopa, L-Dopa, Concerta 18 mg, Discontinued (HRT)

Patient reports decrease in tremors, but increase in facial and verbal tics. Benefit outweighed downside so patient continued under doctor supervision.

Facial Tics, Verbal Tics. (Probably dopamine overexpression as this is a common stimulant side effect.)

Patient describes great improvement of symptoms and ability to walk without assistance but reports that the increased tics are a problem Patient and care physician both agree mobility, is more important.

10mg/twice daily

Nicotine (patch), Oxiracetam, Lions Mane.

Patient in rehab under doctor supervision. Patient reports restoration of ability to feel pleasure in everyday life. However also reports having to cease use of nicotine patch for duration of use due to potential interaction.

Extreme Migraines in first week. Patient advised to discontinue Nicotine patch and reports no further side effects.

Patient reports wanting to repair drug damage but appears to follow several worring patterns and disregards all advice. Seemingly purposely going against all advice and previous observations.

Heart Palpitations, Sunburn, incidence of age spots under intense sun exposure greatly increased.

Patient experienced severe side effects and was advised both previously and during treatment that Alchohol apparently interacts with substance and causes heart difficulties. Patient disregarded all advice and decided that Alchohol was more important. And discontinued use and contact.

*Smoker (Nicotine), Vyvanse 70 mg

Patient reports contradicting Stimulant intensification and Dampening, After cessation of use patient reports measured 10% increase (non-trivial) of processing speed (IQ test) and lasting stimulant efficacy increase.

Patient describes his benefits as follows. "It did not cure me but I am measurably a little faster. I was just about to give up finding anything that worked and even then it only worked a little, but I will take it." Partial remission of symptoms and stimulant intensification.

IDRA-21, PRL-8-53, P-21 (Injected)

Patient reports increased hyperactivity and moderate stimulant sensitivity increase. Reports increase incidence of "Zen Moments" where flow state is achieved.

Decreased P-21 effectiveness. (I have seen reports that Cerebrolysin and it analogues blunt stimulants but this appears to work the other way around.)

Benefits lasted 1 month post treatment. Then faded as patient continued P-21 use. Apparent contraindiction possibility noted. Patient reports he will dicontinue P-21 and start another cycle of 9-me-bc to regain benefits and I await report of results.

Narcan, ginkgo biloba, Bromantane, Alpha Brain, Marijuana, Caffeine.

Patient reports full restoration of previous levels of pleasure in everyday life. Reports restoration of general enjoyment of various activities

7 weeks, Patient reports ceasing all nootropic and drug use 2 weeks post cessation. "I cannot touch pills or anything else anymore man. I will kill myself if I abuse again. I thank god above for this second chance." Direct Quote.

Doctor Supervised; L-dopa, C-dopa, Selegeline, Amphetamine.

Patient reports large reduction in side effects of concurrent medications and cessation of tremors. Patient still requires hospice care but can perform some self care tasks now without assistance.

Reduction in side effects of concurrent medication. Onset of Verbal tics.

Patient reports significant improvement of symptoms and ability to render self care. Condition appears to be continuing to improve with continued use. Patient promises to contact me if she regains the ability to walk without assistance.

20mg/twice daily; (Doctor decided dose upon signs of it working.)

Mr. Happy Stack, Prl-8-53, SSRI (Lexapro)

Patient reports reduction of depressive and anhedonic symptoms with onset of restored dopamine sensitivity. Increased orgasm ability.

Partial Remission of Anhedonic symptoms. Partial restoration of sexual function

Patient reports increased stimulant effectiveness post cessation. No apparent effects on narcolepsy noted in isolation.

Buproprion, Edronax 4 mg (Better Straterra), Concerta 54 mg

Patient reported greatly improved executive function and reduction in depressive symptoms. Stimulan efficacy greatly increased.

Bromantane, Cortexin, Ritalin (4 mg x3)

Patient reports synergistic effect with medications and greatly increased executive function.

Adderall XR 40 mg, Agmatine Sulphate 500 mg, Intuniv 1 mg.

Increase in hyperactivity post cessation (previously lethargic), increase in stimulant efficacy post cessation

Brain Fog, headache during first two weeks of use. (Containdiction with High dose adderall?) Reduced Stimulant efficacy while in use. High dose of 9-me-bc may also be responsible for onset of brain fog.

Cabergoline, Oxytocin 24 ius, Ritalin (3mg x3), Adderall XR 20 mg

Patient reports already possessing hypersexual characteristics common in Aspergers and while his executive function did increase and patient reported greatly enjoying the side effects they were continuing to intensify and were approaching the point of becoming debilitating. Patient reports getting what he wanted out of it.

Extreme Orgasm intensity, Onset of near nightly wet dreams, Onset of Premature ejaculation (1 min to sub 10 seconds.), Sunburn. Patient reports unprovoked spontaneous ejaculation twice nearing the end of the treatment period. Elimination of refractory period reported.

Increased stimulant efficacy, Onset of debatably positive sexual side effects. Paient reports increased test scores in his Senior year of High school. Providing test scores both before during and after. Showing a 20-30% increase in results. Patient indicates little interest in romantic relationships so views the side effects as positive.

4 weeks. Discontinued due to late onset of spontaneous ejaculation during daytime School hours. "I could feel it coming (lol) and it was continuing to get stronger, I was doing Math for gods sake." direct quote. Sexual effects still present 3 months post cessation.

Patient reports increased stimulant efficacy and less problematic behaviours.

(too many) Mr. Happystack, BPC-157, Cerebrolysin, Dihexa, Vyvanse (recreational dosage not given),

Patient reported increased pleasure in everyday life and eliminating caffeine from diet.

2 weeks. Patient reports stopping because he was "worried about toxicity." Direct quote. (Suspect it was more the premature ejaculation but that is irrevalent.)

Oxytocin 24 ius, Cabergoline, Bromantane (100mg sublingually daily), Valerian Root for sleep.

Patient reports greatly increased pleasure in everyday life and decreased symptoms of rigidity. Reduced Anxiety levels.

Onset of premature ejaculation (time not reported). Onset of frequent wet dreams continuing post cessation. Occasional Verbal Tics not previously present. (These sexual side effects appear to be forming a pattern when combined with oxytocin, stimulants, and Cabergoline; This makes sense as on their own they each can have either positive or negative sexual side effects. Oxytocin increases orgasm intensity and decreases the refractory period. As regular dosing upregulates Oxytocin this effect would compound. Cabergoline has been frequently reported to lower orgasm threshhold and greatly reduce the refractory period due to suppression of prolactin. And stimulants are hit or miss at either suppressing sexual desires or greatly enhancing them. As Bromantane and 9-me-bc are noted to permanently upregulate dopamine release and dopamine receptors respectively when combined with suppression of prolactin and artificially inflated oxytocin and you have a recipe for a hair trigger response.)

Increased enjoyment of everyday life. Reduced pattern rigidity. Reduced anxiety levels.

10 weeks. Patient reports greatly enjoying effects and was warned (at 6 weeks) that due to results from other patients effects may be permanent. This seemed only to embolden the patient and he took a slightly higher dose than average. Patient reports not worrying about sunburn as he was African American and rather dark skinned (Black as Night) directly quoted descriptor. Also reports cessation of Bromantane as anything with caffeine is painfully overstimulating now. Reports nightly nocturnal emmissions sometimes twice in one night currently 1 month post cessation.

1 1/2 weeks. Patient reports worsening symptoms OCD symptoms so discontinued.

Piracetam, St.Johns Wort, N-Acetyl Semax Amidate, No Hrt.

Patient reports no longer feeling nothing but still reports feeling depressive symptoms. Patient advised to undergo counciling.

Narcan, (Previously Shrooms, LSD, Ketamine, cocaine, etc.) (How are you alive?!)

Difficult to make out patient would reply with nonsensical rants that from experience indicate someone going under an LSD relapse. You don’t need to ever take it again to experience this. It sticks around forever and can effect you at random times.

Patient reports better functioning but is still in need of constant care. (And house arrest, how did he get the 9-me-bc?)

6 weeks. Because of the cocktail of drugs and the fact that lsd sticks around forever he will probably never fully recover and I do not dare recommend Cerebrolysin due to the growth hormones.

Regained ambulatory function but tremors still present. Requires a walker for long distances.

Continuing to use outside of doctor supervision. Under doctor supervision for 8 weeks.

Cortexin, Semax, Agmatine Sulphate 2g daily. NAC 500 mg

4 weeks. Patient a non responder no effects reported after 4 weeks.

Daytrana 30 mg, Straterra 100 mg

4 weeks. Patient said he wanted to avoid any "Neurotoxic effects" so he would use a low dose. Patient was advised all other patients who received effects were at doses much higher and that 1/10 the next lowest dose would likely produce no noticeable effect. Advice was ignored and patient denounced the substance as "This garbage does not work i want my money back." User was then blocked due to toxicity and harassment.

Anhedonia/Drug damage (Valium, MDMA)/ Suicidal

Patient reports stimulant oversensitivity onset. Mild Hyperactive symptoms.

3 weeks. Decided she did not want to finish the full month as she said it would make her too hyper sensitive to stimulants.

Alchohol (Told me half way through), Coluracetam, BPC-157

Patient reported partial restoration of pleasure sensations. See side effects.

Better ability to feel pleasure in everyday life. Patient stopped treatment early due to side effects and inability to give up alcohol

4 weeks. Patient did not inform me that he was imbibing in alcohol until he began experiencing the side effects I had previously warned about. He asked me what he could do to prevent that and I said that he should discontinue alcohol for duration of use. Patient responded in a way that his dependency and drug seeking behaviour came through. He discontinued treatment.

Remission of damage. Resolvement of anorgasmia. Restoration of Pleasure during actions such as eating.

Patient went into full remission and detailed and proved that he was at a spiritual retreat in the rocky mountains. (Some New age hippy thing) He detailed he got clean but wanted his old feelings back. He got what he wanted.

None reported. Patient detailed that all potential symptoms being experienced were previously present from Hrt.

Patient did not detail why she wished to take the compound as she did not appear to know what nootropics were. Patient reported being fine with the results.

Ritalin 10mg 3x, Triptorelin (at 4 weeks)

Restoration of stimulant function. Improved Executive Function

Worsening of Hypersexual Autistic Personality trait. Patient who was a college student reported previously taking and needing to undergo chemical castration treatment from near the onset of puberty due to problematic desires and lack of impulse control. (Not Minors) Patient reports stunting of growth as a result. (He looks 13 but he is not.) Patient began treatment due to dulling of stimulant efficacy and needing it to function in the day to day. Patient reports notcing the resurgence of desires and required continued treatment patient has never offended and was prescribed such treatment by his psychiatrist due to desires and extreme feeling of discomfort (not trans) brought on by puberty.

Patient got what he needed out of the treatment but the worsening of hypersexuality was highly worrying as was chemical castration treatment. Necessitating I follow up with expounding questions to find out more as I did not want to help a child sex offender. Adequate proof was given and the patient got what he wanted but the situation still rubbed me wrong.

Adderal IR (40 mg 3x daily), fasoracetam (400mg daily), Idra-21, Prl-8-53

Patient reported restoration of stimulant function and diminishing of hyperactive symptoms.

None Reported: Patient reports unreliability of his own senses. Stimulant dulling not reported.

Patient received some relief from ongoing ADHD symptoms but it remains to be seen whether it is permanent.

Gotu Kola, Valerian root, Lions Mane, Vinpocitene

Patient reports onset of mild hyperactive symptoms and partial relief from alexithymia.

Patient reported receiving what she asked for in the form of some relief from trauma induced alexithymia.