ABCDEFGHIJKLMNOPQRSTUVWXYZAAABACADAEAFAGAHAIAJAKALAMANAOAPAQARASATAUAVAWAXAYAZBABBBCBDBEBFBGBHBIBJBKBLBMBNBOBPBQBRBSBTBUBVBWBXBYBZCACBCCCDCECFCGCHCICJCKCL
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Anatomical Structures Cell Types and Biomarkers Table for knee
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Author Name(s):
David Rowe; Martin Lotz; Peter Maye; Dong-Guk Shin
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Author ORCID(s):
0000-0001-7852-7775; 0000-0002-6299-8799: 0000-0003-0098-4399; 0009-0004-4649-7363
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Reviewer(s):Ellen M. Quardokus
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Reviewer ORCID(s):
0000-0001-7655-4833
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General Publication(s):
https://doi.org/10.1136/ard-2022-223227.
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Data DOI:
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Date:
revise for October 1, 2024
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Version Number:v1.3
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AS/1AS/1/LABELAS/1/IDAS/1/NOTEAS/1/ABBRAS/2AS/2/LABELAS/2/IDAS/2/NOTEAS/2/ABBRAS/3AS/3/LABELAS/3/IDAS/3/NOTEAS/3/ABBRAS/4AS/4/LABELAS/4/IDAS/4/NOTEAS/4/ABBRAS/5AS/5/LABELAS/5/IDAS/5/NOTEAS/5/ABBRCT/1CT/1/LABELCT/1/IDCT/1/NOTECT/1/ABBRCT/2CT/2/LABELCT/2/IDCT/2/NOTECT/2/ABBRBGene/1BGene/1/LABELBGene/1/IDBGene/1/NOTEBGene/1/ABBRBGene/2BGene/2/LABELBGene/2/IDBGene/2/NOTEBGene/2/ABBRBGene/3BGene/3/LABELBGene/3/IDBGene/3/NOTEBGene/3/ABBRREF/1REF/1/IDREF/1/NOTES
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Regulatory Chondrocyte 1New term Request CLRegC-1ANGPTL4
angiopoietin like 4
HGNC:16039CHI3L1chitinase 3 like 1HGNC:1932CHI3L2chitinase 3 like 2HGNC:1933https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Regulatory Chondrocyte 2New term Request CLRegC-2MT1G
metallothionein 1G
HGNC:7399MT1E
metallothionein 1E
HGNC:7397MT1Hmetallothionein 1HHGNC:7400https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Effector ChondrocyteNew term Request CLECSTC2stanniocalcin 2HGNC:11374CHADchondroadherinHGNC:1909IGFBP7
insulin like growth factor binding protein 7
HGNC:5476https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Prefibrocartilage ChondrocyteNew term Request CLpreFCPRG4proteoglycan 4HGNC:9364COL2A1
collagen type II alpha 1 chain
HGNC:2200CTHRC1
collagen triple helix repeat containing 1
HGNC:18831https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Fibrocartilage Chondrocyte 1New term Request CLFC-1MSMP
microseminoprotein, prostate associated
HGNC:29663COL3A1
collagen type III alpha 1 chain
HGNC:2201COL1A2collagen type I alpha 2 chainHGNC:2198https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Fibrocartilage Chondrocyte 2New term Request CLFC-2IGFBP5
insulin like growth factor binding protein 5
HGNC:5474PRG4proteoglycan 4HGNC:9364CTHRC1
collagen triple helix repeat containing 1
HGNC:18831https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Homeostatic ChodrocyteNew term Request CLHomCMMP3
matrix metallopeptidase 3
HGNC:7173CCL2
C-C motif chemokine ligand 2
HGNC:10618RCAN1regulator of calcineurin 1HGNC:3040https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Reparative ChondrocyteNew term Request CLRepCCILP
cartilage intermediate layer protein
HGNC:1980LOXlysyl oxidaseHGNC:6664ACANaggrecanHGNC:319https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Prehypertrophic ChondrocyteNew term Request CLpreHTCFSTfollistatinHGNC:3971C11orf96
chromosome 11 open reading frame 96
HGNC:38675INHBAinhibin subunit beta AHGNC:6066https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Medial Condylemedial condyle of femurUBERON:0009984Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Hypertrophic Chondrocytehypertrophic chondrocyteCL:0000743HTCIBSP
integrin binding sialoprotein
HGNC:5341SPP1
secreted phosphoprotein 1
HGNC:11255COL10A1collagen type X alpha 1 chainHGNC:2185https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Regulatory Chondrocyte 1New term Request CLRegC-1ANGPTL4
angiopoietin like 4
HGNC:16039CHI3L1chitinase 3 like 1HGNC:1932CHI3L2chitinase 3 like 2HGNC:1933https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Regulatory Chondrocyte 2New term Request CLRegC-2MT1G
metallothionein 1G
HGNC:7399MT1E
metallothionein 1E
HGNC:7397MT1Hmetallothionein 1HHGNC:7400https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Effector ChondrocyteNew term Request CLECSTC2stanniocalcin 2HGNC:11374CHADchondroadherinHGNC:1909IGFBP7
insulin like growth factor binding protein 7
HGNC:5476https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Prefibrocartilage ChondrocyteNew term Request CLpreFCPRG4proteoglycan 4HGNC:9364COL2A1
collagen type II alpha 1 chain
HGNC:2200CTHRC1
collagen triple helix repeat containing 1
HGNC:18831https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Fibrocartilage Chondrocyte 1New term Request CLFC-1MSMP
microseminoprotein, prostate associated
HGNC:29663COL3A1
collagen type III alpha 1 chain
HGNC:2201COL1A2collagen type I alpha 2 chainHGNC:2198https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Fibrocartilage Chondrocyte 2New term Request CLFC-2IGFBP5
insulin like growth factor binding protein 5
HGNC:5474PRG4proteoglycan 4HGNC:9364CTHRC1
collagen triple helix repeat containing 1
HGNC:18831https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Homeostatic ChodrocyteNew term Request CLHomCMMP3
matrix metallopeptidase 3
HGNC:7173CCL2
C-C motif chemokine ligand 2
HGNC:10618RCAN1regulator of calcineurin 1HGNC:3040https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Reparative ChondrocyteNew term Request CLRepCCILP
cartilage intermediate layer protein
HGNC:1980LOXlysyl oxidaseHGNC:6664ACANaggrecanHGNC:319https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Prehypertrophic ChondrocyteNew term Request CLpreHTCFSTfollistatinHGNC:3971C11orf96
chromosome 11 open reading frame 96
HGNC:38675INHBAinhibin subunit beta AHGNC:6066https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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kneekneeUBERON:0001465knee jointKnee JointUBERON:0001485Distal Femurcondyle of femurUBERON:0009980Lateral Condylelateral condyle of femurUBERON:0009985Articular Cartilage of femurarticular cartilage of jointUBERON:0010996articular chondrocyte of the femurarticular chondrocyteCL:1001607Hypertrophic Chondrocytehypertrophic chondrocyteCL:0000743HTCIBSP
integrin binding sialoprotein
HGNC:5341SPP1
secreted phosphoprotein 1
HGNC:11255COL10A1collagen type X alpha 1 chainHGNC:2185https://doi.org/10.1136/ard-2022-223227https://doi.org/10.1136/ard-2022-223227
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