RENAL DIVISION JOURNAL CLUB
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DATEPRESENTERROOMTOPICJOURNALE-LINK
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CLINICAL JOURNAL CLUB
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5/31/2016A. HussainNCRC Conference Room
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5/25/2016T .ZachariahNCRC Conference Room
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4/26/2016J. NestorNCRC Conference Room
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3/23/2016D. BennettNCRC Conference Room
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2/24/2016B. NavaNCRC Conference Room
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2/11/2016R. RegunathanNCRC Conference Room
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12/22/2015A. HussainKimberg Conference Room (PH8E115)Parathyroidectomy versus Cincalcet for treatment of hypercalcemia in patients with hyperparathyroidism after renal transplant
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11/24/2015T. ZachariahKimberg Conference Room (PH8E115)Results of the landmark SPRINT trial recently published in NEJMNEJMhttp://www.nejm.org/doi/full/10.1056/NEJMoa1511939
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10/20/2015J. NestorKimberg Conference Room (PH8E115)
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9/29/2015D. BennettKimberg Conference Room (PH8E115)Nocturnal Hemodialysis StudyFHN
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8/25/2015R. RegunathanKimberg Conference Room (PH8E115)A randomized trial of intravenous and oral iron in chronic kidney diseaseKI June 2015
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7/28/2015B. NavaKimberg Conference Room (PH8E115)?
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RENAL JOURNAL CLUB
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6/28/2016Richard-Cournand Library (PH9E101)
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6/21/2016Richard-Cournand Library (PH9E101)
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6/14/2016Richard-Cournand Library (PH9E101)
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6/7/2016Krzystof KirylukRichard-Cournand Library (PH9E101)
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5/24/2016Jae Hyung ChangRichard-Cournand Library (PH9E101)
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5/17/2016T. ZachariahRichard-Cournand Library (PH9E101)
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5/10/2016J RadhakrishnanRichard-Cournand Library (PH9E101)
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5/3/2016J. NestorRichard-Cournand Library (PH9E101)
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4/26/2016A. HussainRichard-Cournand Library (PH9E101)
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4/19/2016Ronald ZvitiRichard-Cournand Library (PH9E101)
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4/12/2016Campbell, Sean R. Richard-Cournand Library (PH9E101)
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4/5/2016Fernandez, Hilda E.Richard-Cournand Library (PH9E101)
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3/29/2016Raza MustafaRichard-Cournand Library (PH9E101)
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3/22/2016B. NavaRichard-Cournand Library (PH9E101)
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3/15/2016Yorg Al AzziRichard-Cournand Library (PH9E101)
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3/8/2016F. LinRichard-Cournand Library (PH9E101)
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3/1/2016Eric SiddallRichard-Cournand Library (PH9E101)Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline Kidney Int. 2015 Feb;87(2):323-31. doi: 10.1038/ki.2014.273. Epub 2014 Aug 6.http://www.sciencedirect.com.ezproxy.cul.columbia.edu/science/article/pii/S0085253815300545
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2/23/2016Heather MorrisRichard-Cournand Library (PH9E101)
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2/9/2016D. BennettRichard-Cournand Library (PH9E101)Pharmacological targeting of podocyte actin dynamics via dynamin ameliorates kidney diseaseNature Medicine 21, 601–609 (2015)http://www.nature.com/nm/journal/v21/n6/full/nm.3843.html
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2/2/2016R. RegunathanRichard-Cournand Library (PH9E101)Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice.Nature Medicine (2016) doi:10.1038/nm.4012http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4012.html
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1/26/2016T NickolasRichard-Cournand Library (PH9E101)Vitamin D3 pretreatment regulates renal inflammatory responses during lipopolysaccharide-induced acute kidney injury.Sci Rep. 2015 Dec 22;5:18687http://www.nature.com/articles/srep18687
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1/12/2016J BaraschRichard-Cournand Library (PH9E101)A Programmable Dual-RNA–Guided
DNA Endonuclease in Adaptive
Bacterial Immunity
Science. 2012 Aug 17;337(6096):816-21.http://www.sciencemag.org/content/337/6096/816.full.pdf
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In vivo gene editing in dystrophic mouse muscle and
muscle stem cells
Science. 2015 Dec 31. pii: aad5177.http://www.sciencemag.org/content/early/2015/12/29/science.aad5177.full.pdf
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Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIVN Engl J Med 2014; 370:901-910http://www.nejm.org/doi/full/10.1056/NEJMoa1300662
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1/5/2016Ali GharaviRichard-Cournand Library (PH9E101)PDE3A mutations cause autosomal dominant hypertension with brachydactyly.Nat Genet. 2015 Jun;47(6):647-53.http://www.nature.com/ng/journal/v47/n6/full/ng.3302.html
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.Nat Genet. 2015 Nov;47(11):1282-93. http://www.nature.com/ng/journal/v47/n11/full/ng.3405.html
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12/15/2015R. AvasareRichard-Cournand Library (PH9E101)Immune activation caused by vascular oxidation promotes fibrosis and hypertensionJ Clin Invest Nov 23rd 2015. doi:10.1172/JCI80761http://www.jci.org/articles/view/80761
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12/8/2015R SampognaRichard-Cournand Library (PH9E101)Metabolic co-dependence gives rise to collective oscillations within biofilmsNature 523, 550–554 (30 July 2015)http://www.nature.com/nature/journal/v523/n7562/full/nature14660.html
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12/1/2015R MagistroniRichard-Cournand Library (PH9E101)2-Deoxy-d-Glucose Ameliorates PKD ProgressionJ Am Soc Nephrol 2015, J Am Soc Nephrol. doi:10.1681/ASN.2015030231http://jasn.asnjournals.org/cgi/pmidlookup?view=long&pmid=26534924
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11/24/2015S MohanRichard-Cournand Library (PH9E101)Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron HomeostasisJASN November 2015 vol. 26 no. 11 2800-2814
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11/17/2015Andrew BombackRichard-Cournand Library (PH9E101)Transcriptional regulation of renal dopamine D1 receptor function during oxidative stress.
Hypertension. 2015 May;65(5):1064-72.http://hyper.ahajournals.org/content/65/5/1064.long
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10/27/2015Juan OliverRichard-Cournand Library (PH9E101)Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian KidneyCell Reports Volume 12, Issue 8, 25 August 2015, Pages 1325–1338http://www.sciencedirect.com/science/article/pii/S2211124715007949
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10/20/2015G AppelRichard-Cournand Library (PH9E101)B7–1 Is Not Induced in Podocytes of Human and Experimental Diabetic NephropathyJ Am Soc Nephrol 27: ccc–ccc, 2015. doi: 10.1681/ASN.2015030266http://jasn.asnjournals.org/content/early/2015/08/28/ASN.2015030266.full
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10/13/2015David CohenRichard-Cournand Library (PH9E101)Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established diseaseNat Med. 2015 Sep;21(9):989-97. http://www.nature.com/nm/journal/v21/n9/full/nm.3901.html
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Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosisNat Med. 2015 Sep;21(9):998-1009.http://www.nature.com/nm/journal/v21/n9/full/nm.3902.html
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10/6/2015S Sanna-CherchiRichard-Cournand Library (PH9E101)Identification of cis-suppression of human disease mutations by comparative genomics.Nature. 2015 Aug 13;524(7564):225-9.http://www.nature.com/nature/journal/v524/n7564/full/nature14497.html
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9/29/2015N SteersRichard-Cournand Library (PH9E101)Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus.Nature Immunology 2015, July 2015, Volume 16 No 7.http://www.nature.com/ni/journal/v16/n7/index.html
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9/22/2015Division MeetingRichard-Cournand Library (PH9E101)Review of the ACGME survey
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9/15/2015A ValeriRichard-Cournand Library (PH9E101)Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney diseaseThe Journal of Clinical Investigation, May 11, 2015http://www.jci.org/articles/view/80467 http://dm5migu4zj3pb.cloudfront.net/manuscripts/80000/80467/JCI80467sd.pdf
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9/8/2015Q. Al-AwqatiRichard-Cournand Library (PH9E101)Longitudinal study of living kidney donor glomerular dynamics after nephrectomy
J Clin Invest. 2015 Mar 2;125(3):1311-8http://www.jci.org/articles/view/78885
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6/23/2015D. BennettRichard-Cournand Library (PH9E101)Phosphatidylinositol 3-kinase signaling determines kidney sizeJ Clin Invest. 2015;125(6):2429-2444http://www.jci.org/articles/view/78945
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6/16/2015CANCELLEDRichard-Cournand Library (PH9E101)
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6/9/2015M. KhatriRichard-Cournand Library (PH9E101)Evidence That Links Loss of Cyclooxygenase-2 With
Increased Asymmetric Dimethylarginine
Circulation. 2015;131:633-642http://circ.ahajournals.org/content/early/2014/12/05/CIRCULATIONAHA.114.011591.abstract
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6/2/2015B. NavaRichard-Cournand Library (PH9E101)Unraveling the Role of Podocyte Turnover in Glomerular Aging and InjuryJASN January 9, 2014 ASN.2013050452
http://jasn.asnjournals.org/content/early/2014/01/08/ASN.2013050452.long
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5/19/2015A. GandaRichard-Cournand Library (PH9E101)An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.Nature, Vol 478, Oct 2011, p 197http://www.nature.com/nature/journal/v478/n7368/full/nature10491.html
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5/12/2015M. RaoRichard-Cournand Library (PH9E101)Artificial Sweetners Induce Glucose Intolerance by Altering Gut MetabolismNature, Vol 514, Oct 2014, p 181http://www.nature.com/nature/journal/v514/n7521/full/nature13793.html
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5/5/2015Y. DrexlerRichard-Cournand Library (PH9E101)Integrated compensatory network is activated in the absence of NCC phosphorylationJCI. Published April 20, 2015http://www.jci.org/articles/view/78558#sd
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4/28/2015H. FernandezRichard-Cournand Library (PH9E101)Leptin Mediates the Increase in Blood Pressure Associated with Obesity Cell Press, Volume 159, Issue 6, 4 December 2014, Pages 1404–1416
http://www.sciencedirect.com/science/article/pii/S0092867414014305
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4/21/2015R. RegunathanRichard-Cournand Library (PH9E101)Krüppel-like factor 6 regulates mitochondrial function in the kidney
Journal of Clinical Investigation. March 2015http://www.jci.org/articles/view/77084
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4/14/2015K. KirylukRichard-Cournand Library (PH9E101)Identification of a large set of rare complete human knockouts
Nature Genetics (2015) doi:10.1038/ng.3243http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3243.html
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4/7/2015R. BabeyevRichard-Cournand Library (PH9E101)Preserved Na/HCO3 cotransporter sensitivity to insulin may promote hypertension in metabolic syndromeKidney International (2015) 87, 535–542http://www.nature.com/ki/journal/v87/n3/full/ki2014351a.html
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3/31/2015S. VidiRichard-Cournand Library (PH9E101)
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3/24/2015R. AvasareRichard-Cournand Library (PH9E101)Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation
The Journal of Clinical Investigationhttp://www.jci.org/articles/view/76327
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3/17/2015P. Canetta Richard-Cournand Library (PH9E101)Immunoglobulin isotypes in immune-complex kidney diseaseNature 517, 501–504 (22 January 2015) doi:10.1038/nature13868
Received 28 April 2011 Accepted 16 September 2014 Published online 02 November 2014 Corrected online 21 January 2015
http://www.nature.com/nature/journal/v517/n7535/full/nature13868.html
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3/10/2015N. JainRichard-Cournand Library (PH9E101)CXCL5 Drives Neutrophil Recruitment in
TH17-Mediated GN
CXCL5 Drives Neutrophil Recruitment in Th17-Mediated GN
JASN 16:55-66, 2015
http://jasn.asnjournals.org/content/early/2014/06/04/ASN.2013101061.short
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3/3/2015F. LinRichard-Cournand Library (PH9E101)Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
Cell Stem Cell, Volume 14, Issue 1, 2 January 2014, Pages 53–67

http://ac.els-cdn.com/S1934590913005018/1-s2.0-S1934590913005018-main.pdf?_tid=6d2c21c8-c0df-11e4-81b5-00000aacb35e&acdnat=1425302837_1c73bd83e0ae3768a981bc10850c78f2
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2/24/2015S. CampbellRichard-Cournand Library (PH9E101)Dendritic Cells in Lupus Are Not Required for Activation of T and B Cells but Promote Their Expansion, Resulting in Tissue DamageImmunity. Volume 33, Issue 6, p967–978, 14 December 2010 http://www.cell.com/immunity/abstract/S1074-7613(10)00455-3
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2/10/2015Ali GharaviRichard-Cournand Library (PH9E101)Statin treatment rescues FGFR3 skeletal dysplasia phenotypes. Nature. 2014 Sep 25;513(7519):507-11. doi: 10.1038/nature13775. Epub 2014 Sep 17.www.nature.com/doifinder/10.1038/nature13775
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2/3/2015Faculty meeting Richard-Cournand Library (PH9E101)Review faculty compensation plan--
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1/27/2015J. CrewRichard-Cournand Library (PH9E101)
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1/13/2015G. Dube Richard-Cournand Library (PH9E101)Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosisjci.org Volume 125 Number 1 January 2015http://www.jci.org/articles/view/76902
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1/6/2015G AppelRichard-Cournand Library (PH9E101)Thrombospondin Type-1 Domain-Containing 7A in Idiopathic Membranous Nephropathyn engl j med 371;24 nejm.org december 11, 2014http://www.nejm.org/doi/pdf/10.1056/NEJMoa1409354
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12/16/2014R MagistroniRichard-Cournand Library (PH9E101)Improving Mutation Screening in Familial Hematuric Nephropathies through Next Generation SequencingJASN December 2014 25: 2740-2751http://jasn.asnjournals.org/content/25/12/2740
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12/9/2014J RadhakrishnanRichard-Cournand Library (PH9E101)Inhibition of the mTORC pathway in the antiphospholipid syndromeN Engl J Med. 2014 Jul 24;371(4):303-12.http://www.nejm.org/doi/full/10.1056/NEJMoa1312890
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11/25/2014J BaraschRichard-Cournand Library (PH9E101)Identification of erythroferrone as an erythroid regulator of iron metabolismNature GeneticsNature Genetics, Volume:46, Pages:678–684. Year published: (2014)DOI: doi:10.1038/ng.2996
http://www.nature.com/ng/journal/v46/n7/full/ng.2996.html
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10/28/2014R SampognaRichard-Cournand Library (PH9E101)Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex-http://www.cell.com/cell/abstract/S0092-8674(14)00722-3
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10/21/2014N SteersRichard-Cournand Library (PH9E101)IL-17 Regulates Systemic Fungal Immunity by Controlling the Functional Competence of NK Cells-http://www.sciencedirect.com/science/article/pii/S1074761313005529
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10/14/2014A ValeriRichard-Cournand Library (PH9E101)The role of the HIF pathway in AKI-http://www.jci.org/articles/view/69073
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10/7/2014S MohanRichard-Cournand Library (PH9E101)Immunosuppressive Effects of Erythropoietin on Human Alloreactive T Cells-http://jasn.asnjournals.org/content/25/9/2003.full
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9/30/2014W AhnRichard-Cournand Library (PH9E101)Functional Role of Glucose Metabolism, Osmotic Stress, and Sodium-Glucose Cotransporter Isoform-Mediated Transport on Na+/H+ Exchanger Isoform 3 Activity in the Renal Proximal Tubule-http://jasn.asnjournals.org/content/25/9/2028.abstract
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9/23/2014S Sanna-CerchiRichard-Cournand Library (PH9E101)Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.-http://www.nature.com/ng/journal/vaop/ncurrent/pdf/ng.3066.pdf
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9/16/2014S PrakashRichard-Cournand Library (PH9E101)The oral-facial-digital syndrome gene C2CD3 encodes a
positive regulator of centriole elongation.
-http://www.nature.com/ng/journal/v46/n8/pdf/ng.3031.pdf
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9/9/2014Q. Al-AwqatiRichard-Cournand Library (PH9E101)Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes-http://www.pnas.org/content/111/22/8287
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7/22/2014J. CrewRichard-Cournand Library (PH9E101)Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosisJ Clin Invest. 2014;124(4):1608–1621. doi:10.1172/JCI71195http://www.jci.org.ezproxy.cul.columbia.edu/articles/view/71195
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6/17/2014Rupali AvasareRichard-Cournand Library (PH9E101)Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormonesdoi:10.1038/nature13297www.nature.com/doifinder/10.1038/nature13297
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6/10/2014Jamie HirschRichard-Cournand Library (PH9E101)Delayed Administration of a Single Dose of Lithium Promotes Recovery from AKIJ Am Soc Nephrol 25: 488–500, 2014-
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6/3/2014Eugene EssandohRichard-Cournand Library (PH9E101)Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis–associated glomerular injuryJ Clin Invest.  doi:10.1172/JCI67846. http://www.jci.org/articles/view/67846
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4/8/2014Yelena DrexlerRichard-Cournand Library (PH9E101)Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndromeNature Medicine doi:10.1038/nm.3396http://www.ncbi.nlm.nih.gov/pubmed/24317117
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4/1/2014Jai Radhakrishnan Richard-Cournand Library (PH9E101)Clinical Nephrology 2014
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3/25/2014Eric SiddallRichard-Cournand Library (PH9E101)Regulation of bone remodeling by vasopressin explains the bone loss in hyponatremiaPNAS 2013; 110 (46): 18644-18649http://www.pnas.org.ezproxy.cul.columbia.edu/content/110/46/18644.full.pdf+html
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3/18/2014Meghan SiseRichard-Cournand Library (PH9E101)A Pegylated Leptin Antagonist Ameliorates CKD-Associated Cachexia in Micedoi: 10.1681/ASN.2013040432 http://jasn.asnjournals.org/content/25/1/119.short?rss=1
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3/11/2014Thomas NickolasRichard-Cournand Library (PH9E101)CKD-Induced Wingless/Integration1 Inhibitors and Phosphorus Cause the CKD-Mineral and Bone Disorder doi: 10.1681/ASN.2013080818 http://jasn.asnjournals.org/content/early/2014/02/26/ASN.2013080818.full
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