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Neglected goal (alphabetical order within priority levels)
Level of cause investigation
Link
Relevant framework
DALY burden per year (where applicable, generally drawn from GBD)
Funding level (NIH)
Comments on funding level
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Alzheimer's disease
Internal investigation in progress, some grantmaking
Not available
Prioritized due to Good Ventures interest
2.88E+079.29E+08
3
Animal product alternatives
Pre-2016 internal investigation and associated public write-up, internal investigation, one investment
https://www.openphilanthropy.org/research/cause-reports/animal-product-alternatives
Animal welfareN/ANot sure
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Chronic obstructive pulmonary disease (COPD)
Basic background knowledge
Not available
General human empowerment
6.34E+079.70E+07
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Chronic pain
Basic background knowledge
Not available
General human empowerment
8.65E+074.10E+08
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Emergency global food production scale-up (in preparation for potential agriculture-stifling GCRs such as nuclear winter)
Basic background knowledge
Not availableGCRsN/A
Not sure, believe low
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Malaria
Two series of conversations with informal scientific advisors, gene drive grants
http://files.givewell.org/files/conversations/Micah%20Manary%208-28%20and%209-30-14%20(public).pdf
Global health and development
5.62E+071.83E+08
BMGF and UK government also account for a substantial portion of funding
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Mechanisms of aging
Public write-up, some grantmaking
https://www.openphilanthropy.org/research/cause-reports/scientific-research/mechanisms-aging
General human empowerment
Not on GBD, very large
3.15E+09
Includes all funding tagged as "aging"
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Mental health
Basic background knowledge
Not available
General human empowerment
7.85E+072.45E+09
Includes all mental health from NIH
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Obesity
Internal investigation
Not available
General human empowerment
Not on GBD, large
9.65E+08
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Science relevant to biosecurity and pandemic preparedness
Internal investigation, some grantmaking
Not availableGCRsN/ANot sure
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Tuberculosis
Pre-2016 internal investigation
Not available
Global health and development
4.35E+072.90E+08
BMGF also accounts for a substantial portion of funding
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DALY burden for chronic pain only includes lower back and neck pain. DALY burden for mental health only includes depression.
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All numbers from:
All numbers from:
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http://ghdx.healthdata.org/gbd-results-tool
https://report.nih.gov/categorical_spending.aspx
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