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1 | Guide to interpreting this cost-effectiveness analysis | |||||||||||||||||||||
2 | Sheet descriptions | |||||||||||||||||||||
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4 | Simple iron fortification CEA | This sheet contains a simplified version of the iron fortification CEA that is designed to be comparable to our CEAs of other programs. | ||||||||||||||||||||
5 | Iron fortification CEA | This sheet contains the primary calculations that result in final cost-effectiveness estimates for iron fortification programs. | ||||||||||||||||||||
6 | NI EV | This sheet contains calculations relating to external validity adjustments for the iron fortification program. | ||||||||||||||||||||
7 | Effect on iron intake | This sheet calculates the effect on iron fortification on iron intake | ||||||||||||||||||||
8 | NI Cost | This sheet contains budget and cost information from Nutrition International | ||||||||||||||||||||
9 | VOI | This sheet calculates the learning value of this grant | ||||||||||||||||||||
10 | Iron supplementation CEA | This sheet contains cost-effectiveness calculations for iron supplementation | ||||||||||||||||||||
11 | GBD 2021 estimates | This supplemental sheet contains disease burden and population datasets downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
12 | Iron fortification trials | This supplemental sheet contains information on the trials included in GiveWell's meta-analysis of the effects of iron fortification programs. | ||||||||||||||||||||
13 | Iron supplementation trials | This supplemental sheet contains information on the trials included in the Low et al. 2013 meta-analysis of the effects of iron supplementation programs. | ||||||||||||||||||||
14 | Work capacity supplemental calcs | This supplemental sheet contains additional calculations related to the physical work capacity effects of iron supplementation and fortification programs. | ||||||||||||||||||||
15 | Tetanye cluster adjustment | This sheet contains supplemental calculations for a cluster randomized controlled trial of an iron fortification program. | ||||||||||||||||||||
16 | GBD dietary iron deficiency | This sheet contains additional data downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
17 | Neonatal mortality supplemental | This sheet contains supplemental calculations for estimates of neonatal mortality reductions | ||||||||||||||||||||
18 | Source: GBD 2019 data on infectious disease burden | This supplemental sheet contains disease burden and population datasets downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
19 | NFHS-5 Anemia Data | This supplemental sheet contains population datasets from the National Family Health Survey (NFHS). | ||||||||||||||||||||
20 | GBD 2021 Prevalence Data | This supplemental sheet contains disease burden and population datasets downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
21 | GBD 2021 Anemia YLD Data | This supplemental sheet contains disease burden and population datasets downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
22 | GBD 2021 State-level data | This supplemental sheet contains disease burden and population datasets downloaded from the Institute of Health Metrics (IHME)'s Global Burden of Disease (GBD) project. | ||||||||||||||||||||
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24 | Terminology key | |||||||||||||||||||||
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26 | Terms used across GiveWell's CEAs | |||||||||||||||||||||
27 | Internal validity | Describes an adjustment we make to the treatment effect of an intervention to account for the possibility that the treatment effects found in studies may not represent the true effect the intervention had on the populations studied. | ||||||||||||||||||||
28 | External validity | Describes an adjustment we make to the treatment effect of an intervention to account for differences in the program implementation or populations treated in studies from the program implementation or populations treated by grantee programs. | ||||||||||||||||||||
29 | Leverage | Describes a situation where a grantee's spending on a program causes other organizations or governments to contribute more to the program than they otherwise would have. In most cases, accounting for leverage increases cost-effectiveness | ||||||||||||||||||||
30 | Funging | Describes a situation where a grantee's spending on a program causes other organizations or governments to contribute less to the program than they otherwise would have. In most cases, accounting for funging decreases cost-effectiveness. | ||||||||||||||||||||
31 | Counterfactual | In most cases, describes the state of the world that would exist if we did not provide funding to a grantee for a program. When discussing the "counterfactual value of other actors' spending," we are referring to how much benefit another organization's or government's spending would generate if it were spent on something other than the grantee program. | ||||||||||||||||||||
32 | Moral weights | To compare cost-effectiveness across different programs, we use ‘moral weights’ to quantify the benefits of different program impacts (e.g. increased income vs reduced deaths). We benchmark the value of each benefit to a value of 1, which we define as the value of doubling someone’s consumption for one year. | ||||||||||||||||||||
33 | Philanthropic actors | Non-governmental organizations (NGOs) providing funding to philanthropic programs. | ||||||||||||||||||||
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35 | Source labels | |||||||||||||||||||||
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37 | Source labels used in the CEA | |||||||||||||||||||||
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39 | input | A direct input taken from a source | ||||||||||||||||||||
40 | calc | A value calculated using other values in the same sheet | ||||||||||||||||||||
41 | supp | A value pulled from one of the sheets hosting supplemental information | ||||||||||||||||||||
42 | feed | A value pulled from an earlier section within the same sheet | ||||||||||||||||||||
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44 | GiveWell analyses informing this model | |||||||||||||||||||||
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46 | Analyses referenced across GiveWell's CEAs | |||||||||||||||||||||
47 | GW's moral weights and discount rate | |||||||||||||||||||||
48 | GW's analysis on estimating multiplier for benefits experienced by other household members | |||||||||||||||||||||
49 | GW's supplemental intervention-level adjustments | |||||||||||||||||||||
50 | GiveWell's CEA for GiveDirectly's unconditional cash transfers | |||||||||||||||||||||
51 | GW's analysis of the counterfactual value of other actors' spending | |||||||||||||||||||||
52 | GW's analysis of the counterfactual value of Global Fund spending | |||||||||||||||||||||
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