A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | |
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1 | Parameter name | Unit | Source | Notes | ||||||||||||||||||||||
2 | Disease and demographic parameters | Assumptions and limitations | ||||||||||||||||||||||||
3 | Disability weight for diarrheoa | 0.188 | weight | GBD weights | ||||||||||||||||||||||
4 | Percent of < 5YO suffer diarrhoea per year | 3.90% | % | https://vizhub.healthdata.org/gbd-results/ | * Does not include additional benefits from increasing rates of attending ANC appointments/ births in health facilities. | |||||||||||||||||||||
5 | Percent of children with diarrhoea seek out treatment in absence of intervention | 63% | % | DHS | * Does not include long term benefits, so may underestimate total benefit | |||||||||||||||||||||
6 | Mortality rate diarrheoa <5 YO | 0.06 | rate | https://vizhub.healthdata.org/gbd-results/ | Used death and prevlance numbers for diarrhoeal diseases in Burkina Faso <5 YO. Note this is for diarrheal diseases specifically, not any occurence of diarrhoea | |||||||||||||||||||||
7 | Disability weight for lower respiratory infection | 0.051 | weight | GBD weights | ||||||||||||||||||||||
8 | Percent of < 5YO who suffer lower respiratory infection per year | 0.23% | % | DHS Graph 8 (note it's in French). Divided by two since it is 15% in the 2 years prior to interview | ||||||||||||||||||||||
9 | Percent of children with lower respiratory infection who seek out treatment in absence of intervention | 80% | % | DHS | ||||||||||||||||||||||
10 | Mortality rate lower respiratory infections < 5YO | 0.2 | rate | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7122747/#:~:text=7.4.,-5%20Case%20Fatality&text=Case%20fatality%20ratios%20for%20acute,%E2%80%93142%5D%20in%20developing%20countries. | The GBD estimates place a higher number of deaths than overall prevlance, in burkina faso? I therefore used paper instead, this is in 7.4.5. ('in developing countries'). | |||||||||||||||||||||
11 | Percent of <5YO who have malaria | 35.65% | % | https://vizhub.healthdata.org/gbd-results/ | ||||||||||||||||||||||
12 | Percent of children with malaria that seek out treatment in absence of intervention | 75% | % | https://dhsprogram.com/pubs/pdf/PR139/PR139.pdf graph 8 (in french) | Not sure about this estimate, I used the percent of children with fever whose parents seek out treatment | |||||||||||||||||||||
13 | Disability weight for malaria | 0.051 | weight | GBD weights | Weight for moderate malaria | |||||||||||||||||||||
14 | Mortality rate malaria <5 YO | 0.0118 | rate | https://vizhub.healthdata.org/gbd-results/ | Used death and prevlance numbers for malaria in Burkina Faso <5 YO | |||||||||||||||||||||
15 | Lifespan Burkina Faso | 62 | years | https://data.worldbank.org/indicator/SP.DYN.LE00.IN?locations=BF | ||||||||||||||||||||||
16 | Infant mortality rate in Burkina Faso | 5.30% | % | https://data.worldbank.org/indicator/SP.DYN.IMRT.IN?locations=BF | ||||||||||||||||||||||
17 | Total fertility rate for women in Burkina Faso | 5 | No. children | https://data.worldbank.org/indicator/SP.DYN.TFRT.IN?locations=BF | ||||||||||||||||||||||
18 | ||||||||||||||||||||||||||
19 | Intervention parameters | |||||||||||||||||||||||||
20 | Total number of people reached per year | 2400000 | No | page 2 | ||||||||||||||||||||||
21 | Number of <5YO reached per year | 480000 | No | page 2 | ||||||||||||||||||||||
22 | % increase in consultations for malaria | 42.60% | % | This is the difference between the control and intervention arms, averaged across 3 years. 'Analysis of health facility consultation data' section | I assume a campaign would not last >3 years | |||||||||||||||||||||
23 | % increase in consultations for lower resp infections | 25% | % | This is the difference between the control and intervention arms, averaged across 3 years. 'Analysis of health facility consultation data' section | I assume a campaign would not last >3 years | |||||||||||||||||||||
24 | % increase in consultations for diarrheoa | 80% | % | This is the difference between the control and intervention arms, averaged across 3 years. 'Analysis of health facility consultation data' section | I assume a campaign would not last >3 years | |||||||||||||||||||||
25 | Generalisability discount for RCT | 0.55 | proportion | I am discounting because 1). other regions might not be so amenable to this kind of intervention (rural, cheap radio access, people who lvie within easy walking district of a clinic) and 2). the RCT used a saturation+ design, with high coverage of the radio program. A real situation would likely not achieve as high a coverage. 3). surveyors were not blinded 4). perhaps the most ill kids (who stand to benefit most from treatment) would have recieved clinic treatment anyway- i.e. many the increase in consultations is for kids who are mildly ill | ||||||||||||||||||||||
26 | ||||||||||||||||||||||||||
27 | Reduction in DALYs due to treatment: diarrhoea | 50% | % | Subjective estimate | Couldn't find data. I am assuming that available treatment is not perfect, doesn't always work, isn't always available etc | |||||||||||||||||||||
28 | Reduction in DALYs due to treatment: malaria | 50% | % | Subjective estimate | Assuming that available treatment is not perfect, doesn't always work, isn't always available etc | |||||||||||||||||||||
29 | Reduction in DALYs due to treatment: lower respiratiory infections | 50% | % | Subjective estimate | Assuming that available treatment is not perfect, doesn't always work, isn't always available etc | |||||||||||||||||||||
30 | Reduction in death to to treatment: malaria | 70% | % | Subjective estimate | I think that treatment will be more successful in avoiding death (relative to reducing DALYs) | |||||||||||||||||||||
31 | Reduction in death due to treatment: diarrhoea | 70% | % | Subjective estimate | I think that treatment will be more successful in avoiding death (relative to reducing DALYs) | |||||||||||||||||||||
32 | Reduction in death due to treatment: lower respiratory infections | 70% | % | Subjective estimate | I think that treatment will be more successful in avoiding death (relative to reducing DALYs) | |||||||||||||||||||||
33 | ||||||||||||||||||||||||||
34 | Costs | Unit | Source | Notes | ||||||||||||||||||||||
35 | Recurring costs | |||||||||||||||||||||||||
36 | Airtime | 71216 | $ | Supplementary material Table G | ||||||||||||||||||||||
37 | Rent and utilities | 109946 | $ | Supplementary material Table G | ||||||||||||||||||||||
38 | Supplies | 255790 | $ | Supplementary material Table G | ||||||||||||||||||||||
39 | Travel | 242231 | $ | Supplementary material Table G | ||||||||||||||||||||||
40 | Personnel | 1429020 | $ | Supplementary material Table G | ||||||||||||||||||||||
41 | ||||||||||||||||||||||||||
42 | Capital costs | |||||||||||||||||||||||||
43 | Radio station equipment | 21209 | $ | Supplementary material Table G | ||||||||||||||||||||||
44 | NGO office/ media production equipment | 59231 | $ | Supplementary material Table G | ||||||||||||||||||||||
45 | Vehicles | 16438 | $ | Supplementary material Table G | ||||||||||||||||||||||
46 | ||||||||||||||||||||||||||
47 | Calculations | |||||||||||||||||||||||||
48 | Illness/ death stemming from diarrhoea | |||||||||||||||||||||||||
49 | Number of children who get diarrheoa per year | 18720 | No | |||||||||||||||||||||||
50 | Number children suffering from diarrhoea who get treatment, WO intervention | 11793.6 | No | |||||||||||||||||||||||
51 | Number children who newly seek out treatment | 9434.88 | No | |||||||||||||||||||||||
52 | DALYs averted, by treating more diarrhoea cases | 887 | No | disability weight of diarrhoea x number who newly get treatment x reduction in DALYs from getting treated | ||||||||||||||||||||||
53 | Number of child diarrhoea deaths averted | 396.26496 | No | mortality rate of diarrhoea x reduction in death from getting treatment x number of children newly treated | ||||||||||||||||||||||
54 | ||||||||||||||||||||||||||
55 | Illness/ death stremming from lower respiratory infections | |||||||||||||||||||||||||
56 | Number of children who get lower respiratory infections per yr | 1104 | No | |||||||||||||||||||||||
57 | Number of children suffering from resp infections who get treatment, W/O intervention | 883.2 | No | |||||||||||||||||||||||
58 | Number of children who newly seek out treatment | 220.8 | No | |||||||||||||||||||||||
59 | DALYs averted, by treating more resp infections | 5.6304 | No | |||||||||||||||||||||||
60 | Number of child resp infections deaths averted | 30.912 | No | |||||||||||||||||||||||
61 | ||||||||||||||||||||||||||
62 | Illness/ death stemming from malaria | |||||||||||||||||||||||||
63 | Number of children who get malaria per year | 171120 | No | |||||||||||||||||||||||
64 | Number of children suffering from malaria who get treatment, W/O intervention | 128340 | No | |||||||||||||||||||||||
65 | Number children who newly seek out treatment | 54672.84 | No | |||||||||||||||||||||||
66 | DALYs averted, by treating more malaria cases | 1394.15742 | No | |||||||||||||||||||||||
67 | Number of child malaria deaths averted | 451.5976584 | No | |||||||||||||||||||||||
68 | ||||||||||||||||||||||||||
69 | Cost effectiveness | |||||||||||||||||||||||||
70 | Total DALYs averted from preventing illness (not inc those from averting deaths), with generalisability discount | 1028.999943 | No | Doesn't include DALYs from averting childhood deaths | ||||||||||||||||||||||
71 | Total number of childhood deaths averted, with generalisability discount | 395.4485783 | No | |||||||||||||||||||||||
72 | Number of DALYs from averting childhood death, inc discount | 27800.86869 | DALY equivalents | Using DALY/ lives saved conversion | ||||||||||||||||||||||
73 | Total no. WELLBY-equivalents, inc discount | 96239.36711 | WELLBY equivalents | Using 1 DALY = 3.6 WELLBY conversion | ||||||||||||||||||||||
74 | Total costs | 3381381 | $ | Table 1, total costs (annual costs, average over study period column) | ||||||||||||||||||||||
75 | Total recurring costs | 2108203 | $ | |||||||||||||||||||||||
76 | $/ WELLBY (capital plus recurring costs) | 35.1351126 | $/WELLBY | |||||||||||||||||||||||
77 | $/DALY (capital plus recurring costs) | 121.6286094 | $/DALY | |||||||||||||||||||||||
78 | GD multiples | 4.667695302 | GDX | $164 per WELLBY for GD | ||||||||||||||||||||||
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