Affliations-Department-School

MiR-141-3p Suppresses Tumor Growth and Metastasis in Papillary Thyroid Cancer via Targeting Yin Yang 1

The Affiliated Jiangyin People’s Hospital, School of Medicine, Southeast University

Retracted 27 October 2021

Physcion 8‐O‐β‐Glucopyranoside Exerts Anti‐Tumor Activity Against Non‐Small Cell Lung Cancer by Targeting PPARγ

Department of Respiratory Medicine

Chrysophanol Suppresses Hypoxia‐Induced Epithelial‐Mesenchymal Transition in Colorectal Cancer Cells

The First Affiliated Hospital of Bengbu Medical College

Physcion Synergistically Enhances the Cytotoxicity of Sorafenib in Hepatocellular Carcinoma

Tianjin Medical University Cancer Institute and Hospital

Retracted 28 October 2021

Bufothionine Promotes Apoptosis via Triggering ER Stress and Synergizes with Temozolomide in Glioblastoma Multiforme Cells

The First People's Hospital of Jining

Retracted 28 October 2021

Furowanin A Exhibits Antiproliferative and Pro‐Apoptotic Activities by Targeting Sphingosine Kinase 1 in Osteosarcoma

Amentoflavone Promotes Apoptosis in Non‐Small‐Cell Lung Cancer by Modulating Cancerous Inhibitor of PP2A

Department of Thoracic and Cardiovascular Surgery

The First Affiliated Hospital of Nanjing Medical University

Alpinumisoflavone exhibits anticancer activities in glioblastoma multiforme by suppressing glycolysis

Jiangyin People’s Hospital Affiliated to Nantong University

Alpinumisoflavone Inhibits Tumor Growth and Metastasis in Papillary Thyroid Cancer via Upregulating miR‐141‐3p

Yifu Hospital Affiliated to Nanjing Medical University

Retracted 28 October 2021

Soyasapogenol B Attenuates Laryngeal Carcinoma Progression through Inducing Apoptotic and Autophagic Cell Death

Retracted 28 October 2021

Huaier extract suppresses non‐small cell lung cancer progression through activating NLRP3‐dependent pyroptosis

Department of Respiratory Medicine

Suzhou Science & Technology Town Hospital

Retracted 1 November 2021.

MiR‐93 blocks cell cycle progression and promotes apoptosis in uterine leiomyoma cells by targeting CCND1

Tangshan Gongren Hospital

Physcion 8-O-β-Glucopyranoside Inhibits Testicular Germ Cell Tumors through Regulating MicroRNA-199a

First Affiliated Hospital of Kunming Medical University

Retracted 27 October 2021

Alpinumisoflavone suppresses human Glioblastoma cell growth and induces cell cycle arrest through activating peroxisome proliferator‐activated receptor‐γ

Jiangyin People's Hospital

Euxanthone Represses the Proliferation, Migration, and Invasion of Glioblastoma Cells by modulating STAT3/SHP-1 signalling

Jining First People's Hospital

Retracted 28 October 2021

Long noncoding RNA TUG1 facilitates cell ovarian cancer progression through targeting MiR‐29b‐3p/MDM2 axis

Affiliated Hospital of Qingdao University

Retracted 28 October 2021

Resibufogenin inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation

The Affiliated Hospital of Yan'an University

Euxanthone Impairs the Metastatic Potential of Osteosarcoma by Reducing COX‐2 Expression

the First Affiliated Hospital of Bengbu Medical College

Retracted 28 October 2021

Alpinumisoflavone triggers GSDME ‐dependent pyroptosis in esophageal squamous cell carcinomas

Meizhou People's Hospital

Retracted 28 October 2021

Resibufogenin suppresses growth and metastasis through inducing caspase‐1‐dependent pyroptosis via ROS‐mediated NF‐κB suppression in non‐small cell lung cancer

The First Affiliated Hospital of Nanchang University

Retracted 18 January 2021.

Euxanthone inhibits glycolysis and triggers mitochondria-mediated apoptosis by targeting hexokinase 2 in epithelial ovarian cancer

Qingdao Hiser Hospital of Qingdao University

Autophagy induction by xanthoangelol exhibits anti‐metastatic activities in hepatocellular carcinoma

Department of Pharmacology, School of Pharmacy

Retracted 13 August 2025.

Chrysophanol exhibits inhibitory activities against colorectal cancer by targeting decorin

The First Affiliated Hospital of Bengbu Medical College

Retracted 26 November 2020.

Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-018-01607-w

The Affiliated Hospital of Qingdao University

Retracted 26 November 2020

Resibufogenin suppresses tumor growth and inhibits glycolysis in ovarian cancer by modulating PIM1

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-019-01687-2

Qingdao Hospital of Traditional Chinese Medicine

Retracted 26 November 2020.

Chrysophanol exhibits anti-cancer activities in lung cancer cell through regulating ROS/HIF-1a/VEGF signaling pathway

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-019-01746-8

Hospital Affiliated to Shandong University of Traditional Chinese Medicine

Retracted 28 November 2020.

Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-019-01778-0

The Affiliated Cancer Hospital of Zhengzhou University

Zhengzhou

LncRNA XIST inhibits ovarian cancer cell growth and metastasis via regulating miR-150-5p/PDCD4 signaling pathway

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-020-01808-2

Provincial Hospital Affiliated to Shandong University

Knock-down of LncRNA-XIST induced glioma cell death and inhibited tumorigenesis by regulating miR-137/SLC1A5 axis-mediated ROS production

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-020-01831-3

Jining First People's Hospital

Physcion 8-O-β-glucopyranoside mediates the NLRP3-associated pyroptosis and cell metastasis in the human osteosarcoma cells via ER stress activation

Naunyn-Schmiedeberg s Archives of Pharmacology

10.1007/s00210-020-01836-y

Wuxi Traditional Chinese Medicine Hospital, Nanjing University of Chinese Medicine

Retracted 13 September 2022.

Resibufogenin suppresses tumor growth and Warburg effect through regulating miR-143-3p/HK2 axis in breast cancer

10.1007/s11010-020-03692-z

Department of Breast and Thyroid Surgery

Provincial Hospital Affiliated To Shandong University

Retracted, 18 February 2022

Euxanthone Ameliorates Sevoflurane-Induced Neurotoxicity in Neonatal Mice

10.1007/s12031-019-01303-1

Shandong Provincial Hospital Affiliated to Shandong University

Physcion 8- O -β-glucopyranoside induces apoptosis, suppresses invasion and inhibits epithelial to mesenchymal transition of hepatocellular carcinoma HepG2 cells

10.1016/j.biopha.2016.06.045

Shandong Provincial Hospital Affiliated to Shandong University

Upregulation of miR-124 by physcion 8- O -β-glucopyranoside inhibits proliferation and invasion of malignant melanoma cells via repressing RLIP76

10.1016/j.biopha.2016.09.022

Icaritin induces mitochondrial apoptosis by up-regulating miR-124 in human oral squamous cell carcinoma cells

10.1016/j.biopha.2016.11.023

Department of Oral & Maxillofacial Surgery

The First Affiliated Hospital, Zhengzhou University

Zhengzhou

MiR-370 functions as oncogene in melanoma by direct targeting pyruvate dehydrogenase B

10.1016/j.biopha.2017.03.068

Qilu Hospital of Shandong University

Physcion 8-O-β-glucopyranoside suppresses tumor growth of Hepatocellular carcinoma by downregulating PIM1

10.1016/j.biopha.2017.05.110

Department of Breast and Thyroid Surgery

Shandong Provincial Hospital Affiliated to Shandong University

Physcion blocks cell cycle and induces apoptosis in human B cell precursor acute lymphoblastic leukemia cells by downregulating HOXA5

10.1016/j.biopha.2017.07.149

Affliated Hospital of Southwest Medical University

Alpinumisoflavone radiosensitizes esophageal squamous cell carcinoma through inducing apoptosis and cell cycle arrest

10.1016/j.biopha.2017.08.048

Qilu Hospital of Shandong University (Qingdao)

Physcion 8-O-β-glucopyranosideregulates cell cycle, apoptosis, and invasion in glioblastoma cells through modulating Skp2

10.1016/j.biopha.2017.09.017

Jining First People’s Hospital

Alpinumisoflavone protects against glucocorticoid-induced osteoporosis through suppressing the apoptosis of osteoblastic and osteocytic cells

10.1016/j.biopha.2017.11.136

Department of Human Morphology

Ningbo College of Health Science, No. 51 Xuefu Road, Ningbo, Zhejiang

Physcion induces apoptosis through triggering endoplasmic reticulum stress in hepatocellular carcinoma

10.1016/j.biopha.2018.01.148

The People’s Hospital of Wuhai

Activation of PPARγ mediates icaritin-induced cell cycle arrest and apoptosis in glioblastoma multiforme

10.1016/j.biopha.2018.02.006

Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγ

10.1016/j.biopha.2018.04.014

Department of Pharmacology, School of Pharmacy

Autophagy is a pro-survival mechanism in ovarian cancer against the apoptotic effects of euxanthone

10.1016/j.biopha.2018.04.090

The Affiliated Hospital of Qingdao University

Physcion 8-O-β-glucopyranoside inhibits clear-cell renal cell carcinoma bydownregulating hexokinase II and inhibiting glycolysis

10.1016/j.biopha.2018.05.013

Hospital Affiliated to Shandong University of Traditional Chinese Medicine

Amentoflavone suppresses hepatocellular carcinoma by repressing hexokinase 2 expression through inhibiting JAK2/STAT3 signaling

10.1016/j.biopha.2018.07.177

The second hospital of Hebei Medical University

Shijiazhuang

Physcion induces mitochondria-driven apoptosis in colorectal cancer cells via downregulating EMMPRIN

10.1016/j.ejphar.2015.07.008

Medical College of Qingdao University

Retracted 23 March 2024.

Amentoflavone suppresses tumor growth in ovarian cancer by modulating Skp2

Luoyang Central Hospital, Zhengzhou University

Retracted 23 March 2024.

Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway.

The First Affiliated Hospital of Xinxiang Medical University

Protective autophagy induced by physcion suppresses hepatocellular carcinoma cell metastasis by inactivating the JAK2/STAT3 Axis

Tianjin Medical University Cancer Institute and Hospital

National Clinical Research for Cancer

Alpinumisoflavone causes DNA damage in Colorectal Cancer Cells via blocking DNA repair mediated by RAD51

Puyang Oilfield General Hospital

Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer

The Affiliated Hospital of Qingdao University

Retracted 23 March 2024.

Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer

Gastrointestinal Surgery Department

The People's Hospital of Zhengzhou University

Zhengzhou

Cytoprotective effects of euxanthone against ox-LDL-induced endothelial cell injury is mediated via Nrf2

Physcion 8-O-β-glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer

the First Affiliated Hospital of Zhengzhou University

Zhengzhou

FL118 inhibits viability and induces apoptosis of colorectal cancer cells via inactivating the CIP2A/PP2A axis

Department of Pharmacology, School of Pharmacy

Retracted 23 March 2024.

Amentoflavone suppresses cell proliferation and induces cell death through triggering autophagy-dependent ferroptosis in human glioma

The Affiliated Qingdao Hiser Hospital of Qingdao University

Amentoflavone induces apoptosis and suppresses glycolysis in glioma cells by targeting miR-124-3p

10.1016/j.neulet.2018.08.032

The Affiliated Qingdao Hiser Hospital of Qingdao University

Retracted 2 December 2020.

Physcion 8-O-β-glucopyranoside suppresses the metastasis of breast cancer in vitro and in vivo by modulating DNMT1

10.1016/j.pharep.2016.09.012

Shandong Provincial Hospital Affiliated to Shandong University

Retracted 19 November 2020

Icariin induces apoptosis in acute promyelocytic leukemia by targeting PIM1

10.1016/j.pharep.2017.06.005

Qingdao University Affiliated Hospital

Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation

10.1016/j.pharep.2017.11.001

Qilu Hospital of Shandong University

Retracted 6 November 2020.

Physcion 8-O-β-glucopyranoside exhibits anti-leukemic activity through targeting sphingolipid rheostat

10.1016/j.pharep.2018.03.003

The First People's Hospital of Jining

Retracted 6 November 2020.

MiR-137 suppresses tumor growth and metastasis in clear cell renal cell carcinoma

10.1016/j.pharep.2018.04.006

The Affiliated Hospital of Qingdao University

Retracted 19 November 2020.

Identification of profilin 1 as the primary target for the anti-cancer activities of Furowanin A in colorectal cancer

10.1016/j.pharep.2019.05.007

The Affiliated Hospital of Qingdao University

Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2

Medical College of Qingdao University

Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression

Retracted 7 September 2021

Hispidulin mediates apoptosis in human renal cell carcinoma by inducing ceramide accumulation

Chongqing Normal University

Retracted 7 September 2021

Hispidulin induces ER stress-mediated apoptosis in human hepatocellular carcinoma cells in vitro and in vivo by activating AMPK signaling pathway

10.1038/s41401-018-0159-7

Department of Pharmacology, School of Pharmacy

Retracted due to manipulated figures", May 2020https://journals.lww.com/cardiovascularpharm/Citation/2020/05000/_Retracted__Physcion8_O___Glucopyranoside.15.aspx

Physcion 8-O-β-Glucopyranoside Alleviates Oxidized Low-Density Lipoprotein-Induced Human Umbilical Vein Endothelial Cell Injury by Inducing Autophagy Through AMPK/SIRT1 Signaling

10.1097/fjc.0000000000000680

the First Affiliated Hospital of Xinxiang Medical University

Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer

The Affiliated Hospital of Qingdao University

Endoplasmic reticulum stress triggers Xanthoangelol-induced protective autophagy via activation of JNK/c-Jun Axis in hepatocellular carcinoma

Journal of Experimental & Clinical Cancer Research

10.1186/s13046-018-1012-z

School of Pharmacy, Qingdao University

Euxanthone exhibits anti-proliferative and anti-invasive activities in hepatocellular carcinoma by inducing pyroptosis: preliminary results

European review for medical and pharmacological sciences

10.26355/eurrev_201812_16511

Physcion 8-O-β-glucopyranoside exhibits anti-growth and anti-metastatic activities in ovarian cancer by downregulating miR-25

European review for medical and pharmacological sciences

10.26355/eurrev_201906_18174

Luoyang Central Hospital Affiliated to Zhengzhou University

MicroRNA-29b promotes cell sensitivity to Temozolomide by targeting STAT3 in glioma

European review for medical and pharmacological sciences

10.26355/eurrev_202002_20370

Physcion 8-O-β-glucopyranoside prevents hypoxia-induced epithelial-mesenchymal transition in colorectal cancer HCT116 cells by modulating EMMPRIN

Maternal and child health hospital affiliated to Nanjing Medical University

Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells

Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer

The Affiliated Hospital of Qingdao University

PTTG promotes invasion in human breast cancer cell line by upregulating EMMPRIN via FAK/Akt/mTOR signaling

EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-β-glucopyranoside-induced apoptosis in osteosarcoma cells

Department of Orthopaedic Surgery

The First Affiliated Hospital of Soochow University

Upregulating miR-146a by physcion reverses multidrug resistance in human chronic myelogenous leukemia K562/ADM cells

Affiliated Hospital of Southwest Medical University

Alpinumisoflavone induces apoptosis in esophageal squamous cell carcinoma by modulating miR-370/PIM1 signaling

Physcion induces apoptosis in hepatocellular carcinoma by modulating miR-370

The People’s Hospital of Wuhai

miR-429 mediates tumor growth and metastasis in colorectal cancer

Erratum, 1 February 2019

Alpinumisoflavone suppresses tumour growth and metastasis of clear-cell renal cell carcinoma

Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine

Hispidulin suppresses tumor growth and metastasis in renal cell carcinoma by modulating ceramide-sphingosine 1-phosphate rheostat

Department of Pharmacology, School of Pharmacy