| A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | AA | AB | AC | AD | AE | AF | AG | AH | AI | AJ | AK | AL | AM | AN | AO | AP | AQ | AR | AS | AT | AU | AV | AW | AX | AY | AZ | BA | BB | BC | BD | BE | BF | BG | BH | BI | BJ | BK | BL | BM | BN | BO | BP | BQ | BR | BS | BT | BU | BV | BW | BX | BY | BZ | CA | CB | CC | CD | CE | CF | CG | CH | CI | CJ | CK | CL | CM | CN | CO | CP | CQ | CR | CS | CT | CU | CV | |
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1 | Anatomical Structures, Cell Types and Biomarkers Table for Lymph Node | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3 | Author Name(s): | Marda Jorgensen; Andrea J. Radtke; Natalie Rodriguez | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4 | Author ORCID(s): | 0000-0002-7250-3569; 0000-0003-4379-8967; 0000-0001-6870-0300 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5 | Reviewer(s): | Clive Wasserfall; Elaine Jaffe; Stefania Pittaluga; Robert Seifert; Ellen Quardokus | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
6 | Reviewer ORCID(s): | 0000-0002-3522-8932; 0000-0003-4632-0301; 0000-0001-7688-1439; 0000-0002-4404-8116; 0000-0001-7655-4833 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7 | General Publication(s): | https://doi.org/10.1080/01926230600867727; Anatomy, Lymph Nodes. Iulia Bujoreanu and Vikas Gupta. 2021. https://www.ncbi.nlm.nih.gov/books/NBK557717; Tumors of the Lymph Node and Spleen. L. Jeffrey Medeiros, Dennis P. O'Malley, Nancy P. Caraway, Francisco Vega,Kojo S.J. Elenitoba-Johnson and Megan S. Lim. AFIP Atlas ofTumor Pathology. Series 4. Fascicle 25. Silver Spring, Maryland: American Registry of Pathology; 2017. ISBN 978-1933477-38-1. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8 | Data DOI: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9 | Date: | revise for October 1, 2024 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10 | Version Number: | v1.5 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11 | AS/1 | AS/1/LABEL | AS/1/ID | AS/2 | AS/2/LABEL | AS/2/ID | AS/3 | AS/3/LABEL | AS/3/ID | AS/3/NOTES | AS/4 | AS/4/LABEL | AS/4/ID | AS/4/NOTES | AS/5 | AS/5/LABEL | AS/5/ID | CT/1 | CT/1/LABEL | CT/1/ID | CT/1/NOTES | All Protein Biomarkers from Antibody Based Assays IHC, FACS | Transcriptomics-With References | BGene/1 | BGene/1/LABEL | BGene/1/ID | BGene/2 | BGene/2/LABEL | BGene/2/ID | BGene/3 | BGene/3/LABEL | BGene/3/ID | BGene/4 | BGene/4/LABEL | BGene/4/ID | BGene/5 | BGene/5/LABEL | BGene/5/ID | BGene/6 | BGene/6/LABEL | BGene/6/ID | BGene/7 | BGene/7/LABEL | BGene/7/ID | BGene/8 | BGene/8/LABEL | BGene/8/ID | BGene/9 | BGene/9/LABEL | BGene/9/ID | BGene/10 | BGene/10/LABEL | BGene/10/ID | BGene/11 | BGene/11/LABEL | BGene/11/ID | BGene/12 | BGene/12/LABEL | BGene/12/ID | BGene/13 | BGene/13/LABEL | BGene/13/ID | BGene/14 | BGene/14/LABEL | BGene/14/ID | BGene/15 | BGene/15/LABEL | BGene/15/ID | BGene/16 | BGene/16/LABEL | BGene/16/ID | BGene/17 | BGene/17/LABEL | BGene/17/ID | BGene/18 | BGene/18/LABEL | BGene/18/ID | BGene/19 | BGene/19/LABEL | BGene/19/ID | BProtein/1 | BProtein/1/LABEL | BProtein/1/ID | BProtein/2 | BProtein/2/LABEL | BProtein/2/ID | BProtein/3 | BProtein/3/LABEL | BProtein/3/ID | BProtein/4 | BProtein/4/LABEL | BProtein/4/ID | BProtein/5 | BProtein/5/LABEL | BProtein/5/ID | BProtein/6 | BProtein/6/LABEL | BProtein/6/ID | BProtein/7 | BProtein/7/LABEL |
12 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Myofibroblast | myofibroblast cell | CL:0000186 | Collagen I+, Collagen III+, Elastin+, Desmin+/-, Smooth Muscle Actin+, Vimentin +/- | ACTA2, COL1A1, COL3A1 Predicted | ACTA2 | ACTA2 | HGNC:130 | COL1A1 | COL1A1 | HGNC: 2197 | COL3A1 | COL3A1 | HGNC: 2201 | Collagen I+ | COL1A1 | HGNC: 2197 | Collagen III+ | COL3A1 | HGNC: 2201 | Elastin+ | ELN | HGNC:3327 | Desmin+/- | DES | HGNC:2770 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin +/- | VIM | HGNC:12692 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
13 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Arteriole | arteriole of lymph node | UBERON:8410042 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD59+, CD105+, CD144+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD59+ | CD59 | HGNC:1689 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | |||||||||
14 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Venule | venule of lymph node | UBERON:8410041 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD59+, CD105+, CD144+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD59+ | CD59 | HGNC:1689 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | |||||||||
15 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Trabeculae | trabecula of lymph node | UBERON:0002195 | Myofibroblast | myofibroblast cell | CL:0000186 | Collagen I+, Collagen III+, Elastin+, Desmin+/-, Smooth Muscle Actin+, Vimentin +/- | ACTA2, COL1A1, COL3A1 Predicted | ACTA2 | ACTA2 | HGNC:130 | COL1A1 | COL1A1 | HGNC: 2197 | COL3A1 | COL3A1 | HGNC: 2201 | Collagen I+ | COL1A1 | HGNC: 2197 | Collagen III+ | COL3A1 | HGNC: 2201 | Elastin+ | ELN | HGNC:3327 | Desmin+/- | DES | HGNC:2770 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin +/- | VIM | HGNC:12692 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
16 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Trabeculae | trabecula of lymph node | UBERON:0002195 | Arteriole | arteriole of lymph node | UBERON:8410042 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD105+, CD144+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | HGNC:9459 | ||||||||
17 | lymph node | lymph node | UBERON:0000029 | Capsule | capsule of lymph node | UBERON:0002194 | Trabeculae | trabecula of lymph node | UBERON:0002195 | Venule | venule of lymph node | UBERON:8410041 | Pericyte | pericyte | CL:0000669 | PDGFRalpha+, PDGFRbeta+ | PDGFRalpha+, PDGFRbeta+ Xiang et al., 2020 | PDGFRalpha+ | PDGFRA | HGNC:8803 | PDGFRbeta+ | PDGFRB | HGNC:8804 | PDGFRalpha+ | PDGFRA | HGNC:8803 | PDGFRbeta+ | PDGFRB | HGNC:8804 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
18 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Afferent lymphatic vessel | afferent lymphatic vessel | UBERON:0010396 | Lymphatic Vessels | lymphatic vessel | UBERON:0001473 | Endothelial Cell of Lymphatic Vessel | endothelial cell of lymphatic vessel | CL:0002138 | ACKR4+, CAV1+, CD31+, CD45-, CD73+, Claudin11-, Lyve1-, MARCO-, MFAP4+, Podoplanin+, Prox-1+, TNFRSF9- | ACKR4, CAV1, NUDT4, NT5E Takeda et al., 2019; Xiang et al., 2020 | ACKR4 | ACKR4 | HGNC:1611 | CAV1 | CAV1 | HGNC:1527 | NUDT4 | NUDT4 | HGNC:8051 | NT5E | NT5E | HGNC:8021 | ACKR4+ | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC: 8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin11- | CLDN11 | HGNC:8514 | Lyve1- | LYVE1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
19 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Afferent lymphatic vessel | afferent lymphatic vessel | UBERON:0010396 | Lymphatic Vessels | lymphatic vessel | UBERON:0001473 | Smooth Muscle Cell | Lymphatic vessel smooth muscle cell | CL:0019017 | Smooth Muscle Actin+ | ACTA2 Predicted | ACTA2 | ACTA2 | HGNC:130 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
20 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Macrophage | lymph node subcapsular sinus macrophage | CL:0000887 | CD4+, CD11c+, CD14+, CD68+, CD163+, CD169+, CD206+, DC-SIGN+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, CD163, CD209, MRC1, SIGLEC1 | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD4+ | CD4 | HGNC:1678 | CD11c+ | ITGAX | HGNC:6152 | CD14+ | CD14 | HGNC:1628 | CD68+ | CD68 | HGNC:1693 | CD163+ | CD163 | HGNC:1631 | CD169+ | SIGLEC1 | HGNC:11127 | CD206+ | MRC1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
21 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Marginal Reticular Cell | lymph node marginal reticular cell | CL:0009103 l | Addied to CL | CD31-, CXCL13+, Desmin+, Podoplanin+, Smooth Muscle Actin+, Vimentin+ | CXCL13, ENPP2, TNFSF11 Predicted from mouse-Rodda et al., 2018 | CXCL13 | CXCL13 | HGNC:10639 | ENPP2 | ENPP2 | HGNC:3357 | TNFSF11 | TNFSF11 | HGNC:11926 | CD31- | PECAM1 | HGNC: 8823 | CXCL13+ | CXCL13 | HGNC:10639 | Desmin+ | DES | HGNC:2770 | Podoplanin+ | PDPN | HGNC:29602 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin+ | VIM | HGNC:12692 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
22 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Subcapsular sinus ceiling | subcapsular sinus ceiling | UBERON:8410071 | Added to UBERON | Lymphatic Endothelial Cell -Subcapsular Sinus Ceiling | lymphatic endothelial cell of subcapsular sinus ceiling | CL:0009107 | Addied to CL | ACKR4+, CAV1+, CD31+, CD45-, CD73+, Claudin11-, Lyve1-, MARCO-, MFAP4+, Podoplanin+, Prox-1+, TNFRSF9- | ACKR4, CAV1, NUDT4, NT5E Takeda et al., 2019; Xiang et al., 2020 | ACKR4 | ACKR4 | HGNC:1611 | CAV1 | CAV1 | HGNC:1527 | NUDT4 | NUDT4 | HGNC:8051 | NT5E | NT5E | HGNC:8021 | ACKR4+ | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin11- | CLDN11 | HGNC:8514 | Lyve1- | LYVE1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
23 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Subcapsular sinus floor | subcapsular sinus floor | UBERON:8410072 | Added to UBERON | Lymphatic Endothelial Cell-Subcapsular Sinus Floor | lymphatic endothelial cell of subcapsular sinus floor | CL:0009108 | Addied to CL | ACKR4-, CAV1-, CD9+, CD31+, CD45-, CD73+, Claudin 11-, ICAM1+, Lyve1-, MARCO-, MFAP4-, PDL1+, Podoplanin+, Prox-1+, TNFRSF9+ | CCL20, CXCL1, CXCL5, DARC, LYZ, MARCO, TNFRSF9,THY1 Takeda et al., 2019; Xiang et al., 2020 | CCL20 | CCL20 | HGNC:10619 | CXCL1 | CXCL1 | HGNC:4602 | CXCL5 | CXCL5 | HGNC:10642 | DARC | ACKR1 | HGNC:4035 | LYZ | LYZ | HGNC:6740 | MARCO | MARCO | HGNC:6895 | TNFRSF9 | TNFRSF9 | HGNC:11924 | THY1 | THY1 | HGNC:11801 | ACKR4- | ACKR4 | HGNC:1611 | CAV1- | CAV1 | HGNC:1527 | CD9+ | CD9 | HGNC:1709 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin 11- | CLDN11 | ||||||||||||||||||||||||||||||||||||||||
24 | lymph node | lymph node | UBERON:0000029 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Trabecular sinus | trabecular sinus of lymph node | UBERON:8410032 | Lymphatic Endothelial Cell-Trabeculae | lymphatic endothelial cell of trabecula | CL:0009109 | Addied to CL | ACKR4+, CAV1+, CD31+, CD45-, CD73+, Claudin 11-, Lyve-1+, MARCO-, MFAP4+, Podoplanin+, Prox-1+, TNFRSF9- | ACKR4, LYVE1, MFAP4, NT5E Takeda et al., 2019; Xiang et al., 2020 | ACKR4 | ACKR4 | HGNC:1611 | LYVE1 | LYVE1 | HGNC:14687 | MFAP4 | MFAP4 | HGNC:7035 | NT5E | NT5E | HGNC:8021 | ACKR4+ | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin 11- | CLDN11 | HGNC:8514 | Lyve-1+ | LYVE1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
25 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Venule | venule of lymph node | UBERON:8410041 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD105+, CD144+, Flt1+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD31+ | PECAM1 | HGNC:8823 | CD144+ | CDH5 | HGNC:1764 | Flt1+ | FLT1 | HGNC:3763 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | |||||||||
26 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Arteriole | arteriole of lymph node | UBERON:8410042 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD105+, CD144+, Flt1+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Flt1+ | FLT1 | HGNC:3763 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | |||||||||
27 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Primary Follicle | lymph node primary follicle | UBERON:0010395 | Follicular Dendritic Cell | follicular dendritic cell | CL:0000442 | CD21+, CD32+, CD35+, CXCL13+, HLA-DR+, ICAM-1, Podoplanin+, VCAM-1+ | CR2, CXCL13, FCGRB, MADCAM1, MFGE8, VCAM1 Predicted from mouse-Rodda et al., 2018 | CR2 | CR2 | HGNC:2336 | CXCL13 | CXCL13 | HGNC:10639 | FCGRB | FCGR1B | HGNC:3614 | MADCAM1 | MADCAM1 | HGNC:6765 | MFGE8 | MFGE8 | HGNC:7036 | VCAM1 | VCAM1 | HGNC:12663 | CD21+ | CR2 | HGNC:2336 | CD32+ | FCGR2B | HGNC:3618 | CD35+ | CR1 | HGNC:2334 | CXCL13+ | CXCL13 | HGNC:10639 | HLA-DR+ | CD74 | HGNC:1697 | ICAM-1 | ICAM1 | HGNC:5344 | Podoplanin+ | PDPN | ||||||||||||||||||||||||||||||||||||||||||||||||
28 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Primary Follicle | lymph node primary follicle | UBERON:0010395 | Naive B Cell | naive B cell | CL:0000788 | BCL2+, CD1c+, CD10-, CD20+, CD21+, CD23+, CD27-, CD38+, CD45RA+, HLA-DR+, IgD+, IgM+ | CD19, MS4A1, IGHD, FCER2, HLA-DRA, SELL James et al., 2020 | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | IGHD | IGHD | HGNC:5480 | FCER2 | FCER2 | HGNC:3612 | HLA-DRA | HLA-DRA | HGNC:4947 | SELL | SELL | HGNC:10720 | BCL2+ | BCL2 | HGNC:990 | CD1c+ | CD1C | HGNC:1636 | CD10- | MME | HGNC:7154 | CD20+ | MS4A1 | HGNC:7315 | CD21+ | CR2 | HGNC:2336 | CD23+ | FCER2 | HGNC:3612 | CD27- | CD27 | ||||||||||||||||||||||||||||||||||||||||||||||||
29 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Primary Follicle | lymph node primary follicle | UBERON:0010395 | Memory B Cell | memory B cell | CL:0000787 | CD19+, CD20+, CD27+, CD45RO+, CD79a+, HLA-DR+ | CD19, MS4A1, HLA-DRA James et al., 2020 | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | HLA-DRA | HLA-DRA | HGNC:4947 | CD19+ | CD19 | HGNC:1633 | CD20+ | MS4A1 | HGNC:7315 | CD27+ | CD27 | HGNC:11922 | CD45RO+ | PTPRC | HGNC:9666 | CD79a+ | CD79A | HGNC:1698 | HLA-DR+ | CD74 | HGNC:1697 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
30 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Primary Follicle | lymph node primary follicle | UBERON:0010395 | Macrophage | macrophage | CL:0000235 | CD11b+, CD68+, CD169+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, SIGLEC1 | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD11b+ | ITGAM | HGNC:6149 | CD68+ | CD68 | HGNC:1693 | CD169+ | SIGLEC1 | HGNC:11127 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
31 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | Follicular Dendritic Cell | follicular dendritic cell | CL:0000442 | CD21+, CD23+, CD32+, CD35+, CXCL13+, HLA-DR+, ICAM-1+, Podoplanin+, VCAM-1+ | CR2, CXCL13, FCER2A, FCGRB, MADCAM1, MFGE8, VCAM1 Predicted from mouse-Rodda et al., 2018 | CR2 | CR2 | HGNC:2336 | CXCL13 | CXCL13 | HGNC:10639 | FCER2A | FCER2 | HGNC:3612 | FCGRB | FCGR1B | HGNC:3614 | MADCAM1 | MADCAM1 | HGNC:6765 | MFGE8 | MFGE8 | HGNC:7036 | VCAM1 | VCAM1 | HGNC:12663 | CD21+ | CR2 | HGNC:2336 | CD23+ | FCER2 | HGNC:3612 | CD32+ | FCGR2B | HGNC:3618 | CD35+ | CR1 | HGNC:2334 | CXCL13+ | CXCL13 | HGNC:10639 | HLA-DR+ | CD74 | HGNC:1697 | ICAM-1+ | ICAM1 | |||||||||||||||||||||||||||||||||||||||
32 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | Centrocyte | centrocyte | CL:0009111 | Addied to CL | BCL2-, BCL6+, CD10+, CD20+, CD21+, CD27+, CD38+, CXCR5+, IgD-, Ki67+ | BCL6, CD19, CD83, Mki67, MS4A1 Victora et al., 2012; Milpeid et al., 2018 James et al., 2020 | BCL6 | BCL6 | HGNC:1001 | CD19 | CD19 | HGNC:1633 | CD83 | CD83 | HGNC:1703 | Mki67 | MKI67 | HGNC:7107 | MS4A1 | MS4A1 | HGNC:7315 | BCL2- | BCL2 | HGNC:990 | BCL6+ | BCL6 | HGNC:1001 | CD10+ | MME | HGNC:7154 | CD20+ | MS4A1 | HGNC:7315 | CD21+ | CR2 | HGNC:2336 | CD27+ | CD27 | HGNC:11922 | CD38+ | CD38 | ||||||||||||||||||||||||||||||||||||||||||||
33 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | T Follicular Helper Cell | T follicular helper cell | CL:0002038 | CD3+, CD4+, CD40L+, CD57+, CD69+, CXCR5+, ICOS+, PD-1+ | CD3, CD4, CXCR5, MAF, PDCD1 Locci et al., Immunity 2013 | CD3D | CD3D | HGNC:1673 | CD4 | CD4 | HGNC:1678 | CXCR5 | CXCR5 | HGNC:1060 | MAF | MAF | HGNC:6776 | PDCD1 | PDCD1 | HGNC:8760 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD40L+ | CD40LG | HGNC:11935 | CD57+ | B3GAT1 | HGNC:921 | CD69+ | CD69 | HGNC:1694 | CXCR5+ | CXCR5 | HGNC:1060 | ICOS+ | ICOS | |||||||||||||||||||||||||||||||||||||||||||||
34 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | T Follicular Regulatory Cell | T follicular regulatory cell | CL:0009113 | Addied to CL | CD3+, CD4+, CD25+, FOXP3+ | CD3, CD4, CXCR5, FOXP3, IL2RA Szabo et al., Nat Commun 2019 & Zemmour et al., Nat Immunol 2018 | CD3D | CD3D | HGNC:1673 | CD4 | CD4 | HGNC:1678 | CXCR5 | CXCR5 | HGNC:1060 | FOXP3 | FOXP3 | HGNC:6106 | IL2RA | IL2RA | HGNC:6008 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD25+ | IL2RA | HGNC:6008 | FOXP3+ | FOXP3 | HGNC:6106 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
35 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | Tingible Body Macrophage | lymph node tingible body macrophage | CL:0000888 | CD11b+, CD68+, CD169+, SPARC+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, SIGLEC1, SPARC | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD11b+ | ITGAM | HGNC:6149 | CD68+ | CD68 | HGNC:1693 | CD169+ | SIGLEC1 | HGNC:11127 | SPARC+ | SPARC | HGNC:11219 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
36 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Light Zone | lymph node germinal center light zone | UBERON:8410052 | Plasmablast | plasmablast | CL:0000980 | CD20-, CD27+, CD38++, CD79a+, CD138+, CXCR4+, IRF4+ | Plasmablast | CD38 | CD38 | HGNC:1667 | IRF4 | IRF4 | HGNC:6119 | PRDM1 | PRDM1 | HGNC:9346 | SDC1 | SDC1 | HGNC:10658 | CD20- | MS4A1 | HGNC:7315 | CD27+ | CD27 | HGNC:11922 | CD38++ | CD38 | HGNC:1667 | CD79a+ | CD79A | HGNC:1698 | CD138+ | SDC1 | HGNC:10658 | CXCR4+ | CXCR4 | HGNC:2561 | IRF4+ | IRF4 | ||||||||||||||||||||||||||||||||||||||||||||||||
37 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Dark Zone | lymph node germinal center dark zone | UBERON:8410053 | Centroblast | centroblast | CL:0009112 | Addied to CL | BCL2-, BCL6++, CD10+, CD19+, CD20+, CD27+, CD38+, CXCR4+, HLA-DR+, IgD-, Ki67++, LMO2+ | Centroblast | AICDA | AICDA | HGNC:13203 | BCL6 | BCL6 | HGNC:1001 | CD19 | CD19 | HGNC:1633 | CD27 | CD27 | HGNC:11922 | CXCR4 | CXCR4 | HGNC:2561 | Mki67 | MKI67 | HGNC:7107 | MS4A1 | MS4A1 | HGNC:7315 | BCL2- | BCL2 | HGNC:990 | BCL6++ | BCL6 | HGNC:1001 | CD10+ | MME | HGNC:7154 | CD19+ | CD19 | HGNC:1633 | CD20+ | MS4A1 | HGNC:7315 | CD27+ | CD27 | HGNC:11922 | CD38+ | CD38 | ||||||||||||||||||||||||||||||||||||||
38 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Dark Zone | lymph node germinal center dark zone | UBERON:8410053 | B Cell Zone Reticular Cell | B cell zone reticular cell | CL:0009104 | Addied to CL | CD31-, CXCL12+, Desmin+, Podoplanin+, Smooth Muscle Actin+, Vimentin+ | B Cell Zone Reticular Cell | CXCL12 | CXCL12 | HGNC:10672 | TNFSF11 | TNFSF11 | HGNC:11926 | CD31- | PECAM1 | HGNC:8823 | CXCL12+ | CXCL12 | HGNC:10672 | Desmin+ | DES | HGNC:2770 | Podoplanin+ | PDPN | HGNC:29602 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin+ | VIM | HGNC:12692 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
39 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Mantle Zone | lymph node germinal center mantle zone | UBERON:0010420 | Naive B Cell | naive B cell | CL:0000788 | BCL2+, CD1c+, CD10-, CD20+, CD21+, CD23+,CD38+, CD45RA+, HLA-DR+, IgD+, IgM+ | Naive B Cell | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | IGHD | IGHD | HGNC:5480 | FCER2 | FCER2 | HGNC:3612 | HLA-DRA | HLA-DRA | HGNC:4947 | SELL | SELL | HGNC:10720 | BCL2+ | BCL2 | HGNC:990 | CD1c+ | CD1C | HGNC:1636 | CD10- | MME | HGNC:7154 | CD20+ | MS4A1 | HGNC:7315 | CD21+ | CR2 | HGNC:2336 | CD23+ | FCER2 | HGNC:3612 | CD38+ | CD38 | ||||||||||||||||||||||||||||||||||||||||||
40 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Secondary Follicle | lymph node secondary follicle | UBERON:0010753 | Germinal Center | lymph node germinal center | UBERON:0009039 | Mantle Zone | lymph node germinal center mantle zone | UBERON:0010420 | Memory B Cell | memory B cell | CL:0000787 | CD19+, CD20+, CD45RO+, CD79a+, HLA-DR+ | Memory B Cell | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | HLA-DRA | HLA-DRA | HGNC:4947 | CD19+ | CD19 | HGNC:1633 | CD20+ | MS4A1 | HGNC:7315 | CD45RO+ | PTPRC | HGNC:9666 | CD79a+ | CD79A | HGNC:1698 | HLA-DR+ | CD74 | HGNC:1697 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
41 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Naive CD4+ T cell | naive thymus-derived CD4-positive, alpha-beta T cell | CL:0000895 | CCR7+, CD3+, CD4+, CD8-, CD28+, CD45RA+ | CD3D, CCR7, SELL Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CCR7 | CCR7 | HGNC:1608 | SELL | SELL | HGNC:10720 | CCR7+ | CCR7 | HGNC:1608 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD28+ | CD28 | HGNC:1653 | CD45RA+ | PTPRC | HGNC:9666 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
42 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Memory CD4+ T cell | CD4-positive, alpha-beta memory T cell | CL:0000897 | CD3+, CD4+, CD8-, CD45RA- | CD3D, CXCR6, ITGA1 Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CXCR6 | CXCR6 | HGNC:16647 | ITGA1 | ITGA1 | HGNC:6134 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD45RA- | PTPRC | HGNC:9666 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
43 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Th1 cell | T-helper 1 cell | CL:0000545 | CD3+, CD4+, CD8-, CCR4-, CCR6-, CXCR3+, T-bet+ | CD3D, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CCR4- | CCR4 | HGNC:1605 | CCR6- | CCR6 | HGNC:1607 | CXCR3+ | CXCR3 | HGNC:4540 | T-bet+ | TBX21 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
44 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Th2 cell | T-helper 2 cell | CL:0000546 | CD3+, CD4+, CD8-, CCR4+, CRTH2+, CXCR3-, GATA-3+ | CD3D, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CCR4+ | CCR4 | HGNC:1605 | CRTH2+ | PTGDR2 | HGNC:4502 | CXCR3- | CXCR3 | HGNC:4540 | GATA-3+ | GATA3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
45 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Th17 cell | T-helper 17 cell | CL:0000899 | CD3+, CD4+, CD8-, CD161+, CCR6+, RORC2+ | CD3D, CCR6, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | CCR6 | CCR6 | HGNC:1607 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD161+ | KLRB1 | HGNC:6373 | CCR6+ | CCR6 | HGNC:1607 | RORC2+ | RORC | HGNC:10260 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
46 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | T Regulatory Cell | regulatory T cell | CL:0000815 | CD3+, CD4+, CD25+, FOXP3+ | FOXP3, IL2RA, and CTLA4 Szabo et al., Nat Commun 2019 | FOXP3 | FOXP3 | HGNC:6106 | IL2RA | IL2RA | HGNC:6008 | CTLA4 | CTLA4 | HGNC:2505 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD25+ | IL2RA | HGNC:6008 | FOXP3+ | FOXP3 | HGNC:6106 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
47 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | T Cytotoxic Cell | cytotoxic T cell | CL:0000910 | CD3+, CD8+, Granzyme B+, Perforin+, TIA-1+ | CD3D, CD8A, GZMB, GZMK Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | GZMB | GZMB | HGNC:4709 | GZMK | GZMK | HGNC:4711 | CD3+ | CD3G | HGNC:1675 | CD8+ | CD8A | HGNC:1706 | Granzyme B+ | GZMB | HGNC:4709 | Perforin+ | PRF1 | HGNC:9360 | TIA-1+ | TIA1 | HGNC:11802 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
48 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Naive CD8+ T cell | naive thymus-derived CD8-positive, alpha-beta T cell | CL:0000900 | CCR7+, CD3+, CD4-, CD8+, CD28+, CD45RA+ | CD3D, CD8A, CCR7, SELL Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | CCR7 | CCR7 | HGNC:1608 | SELL | SELL | HGNC:10720 | CCR7+ | CCR7 | HGNC:1608 | CD3+ | CD3G | HGNC:1675 | CD4- | CD4 | HGNC:1678 | CD8+ | CD8A | HGNC:1706 | CD28+ | CD28 | HGNC:1653 | CD45RA+ | PTPRC | HGNC:9666 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
49 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Memory CD8+ T cell | CD8-positive, alpha-beta memory T cell | CL:0000909 | CD3+, CD4-, CD8+, CD45RA- | CD3D, CD8A, CXCR6, ITGA1 Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | CXCR6 | CXCR6 | HGNC:16647 | ITGA1 | ITGA1 | HGNC:6134 | CD3+ | CD3G | HGNC:1675 | CD4- | CD4 | HGNC:1678 | CD8+ | CD8A | HGNC:1706 | CD45RA- | PTPRC | HGNC:9666 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
50 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Natural Killer Cell | natural killer cell | CL:0000623 | CD3-, CD3e+, CD16-, CD56+, CD57-, CD94+, CD117+, CD127+, CD94+, KIR-, NKG2A+, NKG2D+ | ID2, KLRD1 James et al., 2020 | ID2 | ID2 | HGNC:5361 | KLRD1 | KLRD1 | HGNC:6378 | CD3- | CD3G | HGNC:1675 | CD3e+ | CD3E | HGNC:1674 | CD16- | FCGR3A | HGNC:3619 | CD56+ | NCAM1 | HGNC:7656 | CD57- | B3GAT1 | HGNC:11935 | CD94+ | KLRD1 | HGNC:6378 | CD117+ | KIT | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
51 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | T Cell Zone Reticular Cell | T cell zone reticular cell | CL:0009105 | Addied to CL | CCL19+, CCL21+, CD31-, Desmin+, Podoplanin+, Smooth Muscle Actin+, Vimentin+ | CCL19, CCL21, IL7 Predicted from mouse-Rodda et al., 2018 | CCL19 | CCL19 | HGNC:10617 | CCL21 | CCL12 | HGNC:10620 | IL7 | IL7 | HGNC:6023 | CCL19+ | CCL19 | HGNC:10617 | CCL21+ | CCL21 | HGNC:10620 | CD31- | PECAM1 | HGNC:8823 | Desmin+ | DES | HGNC:2770 | Podoplanin+ | PDPN | HGNC:29602 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin+ | VIM | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
52 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Dendritic Cell | dendritic cell | CL:0000451 | CD11c+, CD40+, CD80+, CD83+, CD86+, HLA-DR+, ICAM-1+ | ITGAX, CD40, CD83, HLA-DRA James et al., 2020-Not exhaustive | ITGAX | ITGAX | HGNC:6152 | CD40 | CD40 | HGNC:11919 | CD83 | CD83 | HGNC:1703 | HLA-DRA | HLA-DRA | HGNC:4947 | CD11c+ | ITGAX | HGNC:6152 | CD40+ | CD40 | HGNC:11919 | CD80+ | CD80 | HGNC:1700 | CD83+ | CD83 | HGNC:1703 | CD86+ | CD86 | HGNC:1705 | HLA-DR+ | CD74 | HGNC:1697 | ICAM-1+ | ICAM1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
53 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | T Follicular Regulatory Cell | T follicular regulatory cell | CL:0009113 | Addied to CL | CD3+, CD4+, CD25+, FOXP3+ | CD3, CD4, CXCR5, FOXP3, IL2RA Szabo et al., Nat Commun 2019 & Zemmour et al., Nat Immunol 2018 | CD3D | CD3D | HGNC:1673 | CD4 | CD4 | HGNC:1678 | CXCR5 | CXCR5 | HGNC:1060 | FOXP3 | FOXP3 | HGNC:6106 | IL2RA | IL2RA | HGNC:6008 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD25+ | IL2RA | HGNC:6008 | FOXP3+ | FOXP3 | HGNC:6106 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
54 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Interfollicular Cortex | lymph node interfollicular cortex | UBERON:8410067 | Conventional Dendritic Cell cDC2 | CD1c-positive myeloid dendritic cell | CL:0002399 | CD1c+, CD11c+, HLA-DR+, SIRPa+ | CD1C, CLEC10A, CD86 Villani et al., 2017 Science, James et al., 2020 | CD1C | CD1C | HGNC:1636 | CLEC10A | CLEC10A | HGNC:16916 | CD86 | CD86 | HGNC:1705 | CD1c+ | CD1C | HGNC:1636 | CD11c+ | ITGAX | HGNC:6152 | HLA-DR+ | CD74 | HGNC:1697 | SIRPa+ | SIRPA | HGNC:9662 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
55 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Sinus | lymph node paracortical sinus | UBERON:8410074 | Added to Uberon | Lymphatic Endothelial Cell | endothelial cell of lymphatic vessel | CL:0002138 | ACKR4-, CAV1+, CD31+, CD45-, CD73-, CD209+, Claudin 11-, ICAM1+, Lyve-1+, MARCO+, MFAP4-, PDL1+, Podoplanin+, Prox-1+, STAB2+, TNFRSF9+ | CD209, CLEC4G, CLEC4M, LYVE1, MARCO Takeda et al., 2019; Xiang et al., 2020 | CD209 | CD209 | HGNC:1641 | CLEC4G | CLEC4G | HGNC:24591 | CLEC4M | CLEC4M | HGNC:13523 | LYVE1 | LYVE1 | HGNC:14687 | MARCO | MARCO | HGNC:6895 | ACKR4- | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73- | NT5E | HGNC:8021 | CD209+ | CD209 | HGNC:1641 | Claudin 11- | CLDN11 | |||||||||||||||||||||||||||||||||||||||||||||||
56 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Sinus | lymph node paracortical sinus | UBERON:8410074 | Added to Uberon | T Cell Zone Reticular Cell | T cell zone reticular cell | CL:0009105 | Addied to CL | CCL19+, CCL21+, CD31-, Desmin+, Podoplanin+, Smooth Muscle Actin+, Vimentin+ | CCL19, CCL21, IL7 Predicted from mouse-Rodda et al., 2018 | CCL19 | CCL19 | HGNC:10617 | CCL21 | CCL21 | HGNC:10620 | IL7 | IL7 | HGNC:6023 | CCL19+ | CCL19 | HGNC:10617 | CCL21+ | CCL21 | HGNC:10620 | CD31- | PECAM1 | HGNC:8823 | Desmin+ | DES | HGNC:2770 | Podoplanin+ | PDPN | HGNC:29602 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin+ | VIM | ||||||||||||||||||||||||||||||||||||||||||||||||||||
57 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Sinus | lymph node paracortical sinus | UBERON:8410074 | Added to Uberon | Macrophage | macrophage | CL:0000235 | CD14+/-, CD68+, CD163+, CD169-, CD206+/-, CD209+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, CD163, CD209 | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD14+/- | CD14 | HGNC:1628 | CD68+ | CD68 | HGNC:1693 | CD163+ | CD163 | HGNC:1631 | CD169- | SIGLEC1 | HGNC:11127 | CD206+/- | MRC1 | HGNC:7228 | CD209+ | CD209 | HGNC:1641 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
58 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Arteriole | arteriole of lymph node | UBERON:8410042 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | ||||||||||||||||||||
59 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | capillaries of lymph node | lymphatic capillary | UBERON:0006842 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | ||||||||||||||||||||
60 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | High Endothelial Venule | high endothelial venule of lymph node | UBERON:8410038 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD123+, Collagen IV+, PNAd, Smooth Actin Muscle+ | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD123+ | IL3RA | HGNC:6012 | Collagen IV+ | COL4A2 | HGNC:2203 | PNAd | NTAN1 | HGNC:29909 | Smooth Actin Muscle+ | ACTA2 | HGNC:130 | |||||||||||
61 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Plasmacytoid Dendritic Cell | plasmacytoid dendritic cell, human | CL:0001058 | CD11c-, CD45RA+, CD123+, CD303+, TCF4+ | IL3RA, CLEC4C, GZMB, IGJ Discriminating for this subset; Villani et al., 2017 Science | IL3RA | IL3RA | HGNC:6012 | CLEC4C | CLEC4C | HGNC:13258 | GZMB | GZMB | HGNC:4709 | IGJ | JCHAIN | HGNC:5713 | CD11c- | ITGAX | HGNC:6152 | CD45RA+ | PTPRC | HGNC:9666 | CD123+ | IL3RA | HGNC:6012 | CD303+ | CLEC4C | HGNC:13258 | TCF4+ | TCF4 | HGNC:11634 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
62 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Conventional Dendritic Cell cDC1 | CD141-positive myeloid dendritic cell | CL:0002394 | CD11c+, CD13+, CD141++, HLA-DR+ | XCR1, CADM1, CLEC9A, BATF3, IDO1 James et al., 2020 | XCR1 | XCR1 | HGNC:1625 | CADM1 | CADM1 | HGNC:5951 | CLEC9A | CLEC9A | HGNC:26705 | BATF3 | BATF3 | HGNC:28915 | IDO1 | IDO1 | HGNC:6059 | CD11c+ | ITGAX | HGNC:6152 | CD13+ | ANPEP | HGNC:500 | CD141++ | THBD | HGNC:11784 | HLA-DR+ | CD74 | HGNC:1697 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
63 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Dendritic Cell | dendritic cell | CL:0000451 | CD40+, CD80+, CD83+, CD86+, ICAM-1+, HLA-DR+, S100+ | ITGAX, CD40, CD83, HLA-DRA Predicted from James et al., 2020 | ITGAX | ITGAX | HGNC:6152 | CD40 | CD40 | HGNC:11919 | CD83 | CD83 | HGNC:1703 | HLA-DRA | HLA-DRA | HGNC:4947 | CD40+ | CD40 | HGNC:11919 | CD80+ | CD80 | HGNC:1700 | CD83+ | CD83 | HGNC:1703 | CD86+ | CD86 | HGNC:1705 | ICAM-1+ | ICAM1 | HGNC:5344 | HLA-DR+ | CD74 | HGNC:1697 | S100+ | S100A12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
64 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Naive CD4+ T cell | naive thymus-derived CD4-positive, alpha-beta T cell | CL:0000895 | CCR7+, CD3+, CD4+, CD8-, CD28+, CD45RA+ | CD3D, CCR7, SELL Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CCR7 | CCR7 | HGNC:1608 | SELL | SELL | HGNC:10720 | CCR7+ | CCR7 | HGNC:1608 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD28+ | CD28 | HGNC:1653 | CD45RA+ | PTPRC | HGNC:9666 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
65 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Memory CD4+ T cell | CD4-positive, alpha-beta memory T cell | CL:0000897 | CD3+, CD4+, CD8-, CD45RA- | CD3D, CXCR6, ITGA1 Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CXCR6 | CXCR6 | HGNC:16647 | ITGA1 | ITGA1 | HGNC:6134 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD45RA- | PTPRC | HGNC:9666 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
66 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Th1 cell | T-helper 1 cell | CL:0000545 | CD3+, CD4+, CD8-, CCR4-, CCR6-, CXCR3+, T-bet+ | CD3D, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CCR4- | CCR4 | HGNC:1605 | CCR6- | CCR6 | HGNC:1607 | CXCR3+ | CXCR3 | HGNC:4540 | T-bet+ | TBX21 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
67 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Th2 cell | T-helper 2 cell | CL:0000546 | CD3+, CD4+, CD8-, CCR4+, CRTH2+, CXCR3-, GATA-3+ | CD3D, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CCR4+ | CCR4 | HGNC:1605 | CRTH2+ | PTGDR2 | HGNC:4502 | CXCR3- | CXCR3 | HGNC:4540 | GATA-3+ | GATA3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
68 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Th17 cell | T-helper 17 cell | CL:0000899 | CD3+, CD4+, CD8-, CD161+, CCR6+, RORC2+ | CD3D, CCR6, IL7R, ID2 James et al., 2020 | CD3D | CD3D | HGNC:1673 | CCR6 | CCR6 | HGNC:1607 | IL7R | IL7R | HGNC:6024 | ID2 | ID2 | HGNC:5361 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD8- | CD8A | HGNC:1706 | CD161+ | KLRB1 | HGNC:6373 | CCR6+ | CCR6 | HGNC:1607 | RORC2+ | RORC | HGNC:10260 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
69 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Gamma/Delta T cells | gamma-delta T cell | CL:0000798 | CD3+, TCRgamma/delta+ | CD3D, TRDC, ID2, KLRD1 James et al., 2020 | CD3D | CD3D | HGNC:1673 | TRDC | TRDC | HGNC:12253 | ID2 | ID2 | HGNC:5361 | KLRD1 | KLRD1 | HGNC:6378 | CD3+ | CD3G | HGNC:1675 | TCRgamma/delta+ | TRG | HGNC:12271 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
70 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | T Regulatory Cell | regulatory T cell | CL:0000815 | CD3+, CD4+, CD25+, FOXP3+ | FOXP3, IL2RA, and CTLA4 Szabo et al., Nat Commun 2019 | FOXP3 | FOXP3 | HGNC:6106 | IL2RA | IL2RA | HGNC:6008 | CTLA4 | CTLA4 | HGNC:2505 | CD3+ | CD3G | HGNC:1675 | CD4+ | CD4 | HGNC:1678 | CD25+ | IL2RA | HGNC:6008 | FOXP3+ | FOXP3 | HGNC:6106 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
71 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | T Cytotoxic Cell | cytotoxic T cell | CL:0000910 | CD3+, CD8+, Granzyme B+, Perforin+, TIA-1+ | CD3D, CD8A, GZMB, GZMK Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | GZMB | GZMB | HGNC:4709 | GZMK | GZMK | HGNC:4711 | CD3+ | CD3G | HGNC:1675 | CD8+ | CD8A | HGNC:1706 | Granzyme B+ | GZMB | HGNC: 4709 | Perforin+ | PRF1 | HGNC:9360 | TIA-1+ | TIA1 | HGNC:11802 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
72 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Naive CD8+ T cell | naive thymus-derived CD8-positive, alpha-beta T cell | CL:0000900 | CCR7+, CD3+, CD4-, CD8+, CD28+, CD45RA+ | CD3D, CD8A, CCR7, SELL Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | CCR7 | CCR7 | HGNC:1608 | SELL | SELL | HGNC:10720 | CCR7+ | CCR7 | HGNC:1608 | CD3+ | CD3G | HGNC:1675 | CD4- | CD4 | HGNC:1678 | CD8+ | CD8A | HGNC:1706 | CD28+ | CD28 | HGNC:1653 | CD45RA+ | PTPRC | HGNC:9666 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
73 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Memory CD8+ T cell | CD8-positive, alpha-beta memory T cell | CL:0000909 | CD3+, CD4-, CD8+, CD45RA- | CD3D, CD8A, CXCR6, ITGA1 Szabo et al., Nat Commun 2019; James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | CXCR6 | CXCR6 | HGNC:16647 | ITGA1 | ITGA1 | HGNC:6134 | CD3+ | CD3G | HGNC:1675 | CD4- | CD4 | HGNC:1678 | CD8+ | CD8A | HGNC:1706 | CD45RA- | PTPRC | HGNC:9666 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
74 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Natural Killer Cell | natural killer cell | CL:0000623 | CD3-, CD3e+, CD16-, CD56+, CD57-, CD94+, CD117+, CD127+, CD94+, KIR-, NKG2A+, NKG2D+ | ID2, KLRD1 James et al., 2020 | ID2 | ID2 | HGNC:5361 | KLRD1 | KLRD1 | HGNC:6378 | CD3- | CD3G | HGNC:1675 | CD3e+ | CD3E | HGNC:1674 | CD16- | FCGR3A | HGNC:3619 | CD56+ | NCAM1 | HGNC:7656 | CD57- | B3GAT1 | HGNC:11935 | CD94+ | KLRD1 | HGNC:6378 | CD117+ | KIT | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
75 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Mast Cell | mast cell | CL:0000097 | CD117+, Tryptase+ | KIT, MS4A2, TPSAB1, TPSB2 James et al., 2020 | KIT | KIT | HGNC:6342 | MS4A2 | MS4A2 | HGNC:7316 | TPSAB1 | TPSAB1 | HGNC:12019 | TPSB2 | TPSB2 | HGNC:14120 | CD117+ | KIT | HGNC:6342 | Tryptase+ | TPSAB1 | HGNC:12019 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
76 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Plasma Cell | plasma cell | CL:0000786 | CD20-, CD38++, CD79a+, CD138+, Ig+, IRF4+ | CD38, IRF4, PRDM1, SDC1 Milpeid et al., 2018 James et al., 2020 | CD38 | CD38 | HGNC:1667 | IRF4 | IRF4 | HGNC:6119 | PRDM1 | PRDM1 | HGNC:9346 | SDC1 | SDC1 | HGNC:10658 | CD20- | MS4A1 | HGNC:7315 | CD38++ | CD38 | HGNC:1667 | CD79a+ | CD79A | HGNC:1698 | CD138+ | SDC1 | HGNC:10658 | IRF4+ | IRF4 | HGNC:6119 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
77 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | Monocytoid B Cell | monocytoid B Cell | CL:0009114 | Addied to CL | AID+, CD19+, CD27-, IgM+ | Predicted: AICDA, CD19, IGHM | AICDA | AICDA | HGNC:13203 | CD19 | CD19 | HGNC:1633 | IGHM | IGHM | HGNC:5541 | AID | AICDA | HGNC:13203 | CD19+ | CD19 | HGNC:1633 | CD27- | CD27 | HGNC:11922 | IgM+ | FCAMR | HGNC:24692 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
78 | lymph node | lymph node | UBERON:0000029 | Cortex | cortex of lymph node | UBERON:0002006 | Paracortex | lymph node paracortex | UBERON:8410066 | Paracortical Cord | lymph node paracortical cord | UBERON:8410075 | Added to Uberon | B Cell | B cell | CL:0000236 | CD20+, CD79a+ | CD19, MS4A1, HLA-DRA James et al., 2020 | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | HLA-DRA | HLA-DRA | HGNC:4947 | CD20+ | MS4A1 | HGNC:7315 | CD79a+ | CD79A | HGNC:1698 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
79 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Sinus | lymph node medullary sinus | UBERON:0009744 | Macrophage | macrophage | CL:0000235 | CD11b+, CD68+, CD169+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, ITGAM, SIGLEC1 | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD11b+ | ITGAM | HGNC:6149 | CD68+ | CD68 | HGNC:1693 | CD169+ | SIGLEC1 | HGNC:11127 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
80 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Medullary Reticular Cell | medullary reticular cell | CL:0009106 | Addied to CL | CD31-, CXCL12+, Desmin+, Podoplanin+, Smooth Muscle Actin+, Vimentin+ | CXCL12,TNFSF11 Predicted from mouse-Rodda et al., 2018 | CXCL12 | CXCL12 | HGNC:10672 | TNFSF11 | TNFSF11 | HGNC:11926 | CD31- | PECAM1 | HGNC:8823 | CXCL12+ | CXCL12 | HGNC:10672 | Desmin+ | DES | HGNC:2770 | Podoplanin+ | PDPN | HGNC:29602 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | Vimentin+ | VIM | HGNC:12692 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
81 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | T Cell | T Cell | CL:0000084 | CD3+, CD4+/- or CD8+/- | CD3D, CD4 or CD8A James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD4 | CD4 | HGNC:1678 | CD3+ | CD3G | HGNC:1675 | CD4+/- or CD8+/- | CD4, CD8A | HGNC:1678, HGNC:1706 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
82 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | T Cell | T Cell | CL:0000084 | CD3+, CD4+/- or CD8+/- | CD3D, CD4 or CD8A James et al., 2020 | CD3D | CD3D | HGNC:1673 | CD8A | CD8A | HGNC:1706 | CD3+ | CD3G | HGNC:1675 | CD4+/- or CD8+/- | CD4, CD8A | HGNC:1678, HGNC:1706 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
83 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Sinus | lymph node medullary sinus | UBERON:0009744 | Lymphatic Endothelial Cell | endothelial cell of lymphatic vessel | CL:0002138 | ACKR4-, CAV1+, CD31+, CD45-, CD73-, CD209+, Claudin 11-, ICAM1+, Lyve-1+, MARCO+, MFAP4-, PDL1+, Podoplanin+, Prox-1+, STAB2+, TNFRSF9+ | CD209, CLEC4G, CLEC4M, LYVE1, MARCO Takeda et al., 2019 | CD209 | CD209 | HGNC:1641 | CLEC4G | CLEC4G | HGNC:24591 | CLEC4M | CLEC4M | HGNC:13523 | LYVE1 | LYVE1 | HGNC:14687 | MARCO | MARCO | HGNC:6895 | ACKR4- | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73- | NT5E | HGNC:8021 | CD209+ | CD209 | HGNC:1641 | Claudin 11- | CLDN11 | ||||||||||||||||||||||||||||||||||||||||||||||||
84 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Plasma Cell | plasma cell | CL:0000786 | CD20-, CD27+, CD38++, CD79a+, CD138+, Ig+, IRF4+ | CD38, IRF4, PRDM1, SDC1 Milpeid et al., 2018 James et al., 2020 | CD38 | CD38 | HGNC:1667 | IRF4 | IRF4 | HGNC:6119 | PRDM1 | PRDM1 | HGNC:9346 | SDC1 | SDC1 | HGNC:10658 | CD20- | MS4A1 | HGNC:7315 | CD27+ | CD27 | HGNC:11922 | CD38++ | CD38 | HGNC:1667 | CD79a+ | CD79A | HGNC:1698 | CD138+ | SDC1 | HGNC:10658 | IRF4+ | IRF4 | HGNC:6119 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
85 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | B Cell | B cell | CL:0000236 | CD19+, CD20+, CD79a+ | CD19, MS4A1, HLA-DRA James et al., 2020 | CD19 | CD19 | HGNC:1633 | MS4A1 | MS4A1 | HGNC:7315 | HLA-DRA | HLA-DRA | HGNC:4947 | CD19+ | CD19 | HGNC:1633 | CD20+ | MS4A1 | HGNC:7315 | CD79a+ | CD79A | HGNC:1698 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
86 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Mast Cell | mast cell | CL:0000097 | CD117+, Tryptase+ | KIT, TPSB2, TPSAB1, MS4A2 James et al., 2020 | KIT | KIT | HGNC:6342 | TPSB2 | TPSB2 | HGNC:14120 | TPSAB1 | TPSAB1 | HGNC:12019 | MS4A2 | MS4A2 | HGNC:7316 | CD117+ | KIT | HGNC:6342 | Tryptase+ | TPSAB1 | HGNC:12019 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
87 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Macrophage | macrophage | CL:0000235 | CD14+, CD68+, CD206+, DC-SIGN+, MARCO+ | CD4, CD14, HLA-DRA, ITGAX General macrophage signature from James et al., 2020; Predicted: CD68, CD209, MARCO, MRC1 | CD4 | CD4 | HGNC:1678 | CD14 | CD14 | HGNC:1628 | HLA-DRA | HLA-DRA | HGNC:4947 | ITGAX | ITGAX | HGNC:6152 | CD14+ | CD14 | HGNC:1628 | CD68+ | CD68 | HGNC:1693 | CD206+ | MRC1 | HGNC:7228 | DC-SIGN+ | CD209 | HGNC:1641 | MARCO+ | MARCO | HGNC:6895 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
88 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Plasmablast | plasmablast | CL:0000980 | CD20-, CD38++, CD79a+, CD138+, CXCR4+, IRF4+ | CD38, IRF4, PRDM1, SDC1 Milpeid et al., 2018 James et al., 2020 | CD38 | CD38 | HGNC:1667 | IRF4 | IRF4 | HGNC:6119 | PRDM1 | PRDM1 | HGNC:9346 | SDC1 | SDC1 | HGNC:10658 | CD20- | MS4A1 | HGNC:7315 | CD38++ | CD38 | HGNC:1667 | CD79a+ | CD79A | HGNC:1698 | CD138+ | SDC1 | HGNC:10658 | CXCR4+ | CXCR4 | HGNC:2561 | IRF4+ | IRF4 | HGNC:6119 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
89 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Medullary Cord | lymph node medullary cord | UBERON:0009745 | Dendritic Cell | dendritic cell | CL:0000451 | CD11c+, HLA-DR+, PD-L1+ | CD40, CD83, HLA-DRA James et al., 2020-Not exhaustive | CD40 | CD40 | HGNC:11919 | CD83 | CD83 | HGNC:1703 | HLA-DRA | HLA-DRA | HGNC:4947 | CD11c+ | ITGAX | HGNC:6152 | HLA-DR+ | CD74 | HGNC:1697 | PD-L1+ | CD274 | HGNC:17635 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
90 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Lymphatic Artery | lymph node artery | UBERON:8410034 | Arteriole | medullary arteriole of lymph node | UBERON:8410035 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD105+, CD144+, Podoplanin-, PROX-1-, | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | HGNC:9459 | |||||
91 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Hilar Vein | lymph node vein | UBERON:8410033 | Venule | medullary venule of lymph node | UBERON:8410036 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD105+, CD144+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Podoplanin- | PDPN | HGNC:29602 | PROX-1- | PROX1 | HGNC:9459 | |||||
92 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Medulla | medulla of lymph node | UBERON:0002007 | Pericyte | pericyte cell | CL:0000669 | PDGFRalpha+, PDGFRbeta+ | PDGFRalpha+, PDGFRbeta+ Xiang et al., 2020 | PDGFRalpha+ | PDGFRA | HGNC:8803 | PDGFRbeta+ | PDGFRB | HGNC:8804 | PDGFRalpha+ | PDGFRA | HGNC:8803 | PDGFRbeta+ | PDGFRB | HGNC:8804 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
93 | lymph node | lymph node | UBERON:0000029 | Medulla | medulla of lymph node | UBERON:0002007 | Subcapsular Sinus | subcapsular sinus of lymph node | UBERON:0005463 | Lymphatic Endothelial Cell of Medulla Ceiling | lymphatic endothelial cell of medulla ceiling | CL:0009110 | Addied to CL | ACKR4+, CAV1+, CD31+, CD45-, CD73+, Claudin 11-, Lyve-1+, MARCO-, MFAP4+, Podoplanin+, Prox-1+, TNFRSF9- | ACKR4, LYVE1, MFAP4, NT5E Takeda et al, 2019 | ACKR4 | ACKR4 | HGNC:1611 | LYVE1 | LYVE1 | HGNC:14687 | MFAP4 | MFAP4 | HGNC:7035 | NT5E | NT5E | HGNC:8021 | ACKR4+ | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin 11- | CLDN11 | HGNC:8514 | Lyve-1+ | LYVE1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
94 | lymph node | lymph node | UBERON:0000029 | Hilum | hilum of lymph node | UBERON:0035495 | Efferent Lymphatics | efferent lymphatic vessel | UBERON:0010397 | Lymphatic Endothelial Cell | endothelial cell of lymphatic vessel | CL:0002138 | ACKR4+, CAV1+, CD31+, CD45-, CD73+, Claudin 11-, Lyve-1-, MARCO-, MFAP4+, Podoplanin+, Prox-1+, ,TNFRsF9- | ACKR4, CAV1, NUDT4, NT5E Takeda et al., 2019; Xiang et al., 2020 | ACKR4 | ACKR4 | HGNC:1611 | CAV1 | CAV1 | HGNC:1527 | NUDT4 | NUDT4 | HGNC:8051 | NT5E | NT5E | HGNC:8021 | ACKR4+ | ACKR4 | HGNC:1611 | CAV1+ | CAV1 | HGNC:1527 | CD31+ | PECAM1 | HGNC:8823 | CD45- | PTPRC | HGNC:9666 | CD73+ | NT5E | HGNC:8021 | Claudin 11- | CLDN11 | HGNC:8514 | Lyve-1- | LYVE1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
95 | lymph node | lymph node | UBERON:0000029 | Hilum | hilum of lymph node | UBERON:0035495 | Efferent Lymphatics | efferent lymphatic vessel | UBERON:0010397 | Smooth Muscle Cell | lymphatic vessel smooth muscle cell | CL:0019017 | Smooth Muscle Actin+ | ACTA2 Predicted | ACTA2 | ACTA2 | HGNC:130 | Smooth Muscle Actin+ | ACTA2 | HGNC:130 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
96 | lymph node | lymph node | UBERON:0000029 | Hilum | hilum of lymph node | UBERON:0035495 | Sympathetic nerve | sympathetic nerve | UBERON:0034729 | Sympathetic Neuron | sympathetic neuron | CL:0011103 | CD56+, UCHL1+ | NCAM1, UCHL1 Predicted | NCAM1 | NCAM1 | HGNC:7656 | UCHL1 | UCHL1 | HGNC:12513 | CD56+ | NCAM1 | HGNC:7656 | UCHL1+ | UCHL1 | HGNC:12513 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
97 | lymph node | lymph node | UBERON:0000029 | Hilum | hilum of lymph node | UBERON:0035495 | Lymphatic Artery | lymph node artery | UBERON:8410034 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD59+, CD105+, CD144+, CX40+, ICAM1+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD59+ | CD59 | HGNC:1689 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | CX40+ | GJA5 | HGNC:4279 | ICAM1+ | ICAM1 | |||||||||
98 | lymph node | lymph node | UBERON:0000029 | Hilum | hilum of lymph node | UBERON:0035495 | Hilar Vein | lymph node vein | UBERON:8410033 | Blood Vessel Endothelial Cell | blood vessel endothelial cell | CL:0000071 | CD31+, CD34+, CD59+, CD105+, CD144+, Endomucin+, ICAM1+, Podoplanin-, PROX-1- | CAV1, CCL14, CD34, CD74, CD209, CD300LG, DARC, EMCN, ESAM, ICAM1, JAM2, HLA-DRA, HLA-DRB1, HLA-DPA1, HLA-DPB1, MARCO, PLVAP, PVRL2, SPARCL1, PECAM1 inferred general signature from Takeda 2020 | CAV1 | CAV1 | HGNC:1527 | CCL14 | CCL14 | HGNC:10612 | CD34 | CD34 | HGNC:1662 | CD74 | CD74 | HGNC:1697 | CD209 | CD209 | HGNC:1641 | CD300LG | CD300LG | HGNC:30455 | DARC | ACKR1 | HGNC:4035 | EMCN | EMCN | HGNC:16041 | ESAM | ESAM | HGNC:17474 | ICAM1 | ICAM1 | HGNC:5344 | JAM2 | JAM2 | HGNC:14686 | HLA-DRA | HLA-DRA | HGNC:4947 | HLA-DRB1 | HLA-DRB1 | HGNC:4948 | HLA-DPA1 | HLA-DPA1 | HGNC:4938 | HLA-DPB1 | HLA-DPB1 | HGNC:4940 | MARCO | MARCO | HGNC: 6895 | PLVAP | PLVAP | HGNC:13635 | PVRL2 | NECTIN2 | HGNC:9707 | SPARCL1 | SPARCL1 | HGNC:11220 | CD31+ | PECAM1 | HGNC:8823 | CD34+ | CD34 | HGNC:1662 | CD59+ | CD59 | HGNC:1689 | CD105+ | ENG, endoglin | HGNC:3349 | CD144+ | CDH5 | HGNC:1764 | Endomucin+ | EMCN | HGNC:16041 | ICAM1+ | ICAM1 | |||||||||
99 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
100 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||