Date of Advance online publication

Efficacy and Safety of Acoramidis in Japanese Adults With Symptomatic Transthyretin Amyloid Cardiomyopathy

Jin Endo, Kenichi Tsujita, Chisato Izumi, Toshiyuki Yano, Hiroaki Kitaoka, Yoshiki Sekijima, Nobuhiro Tahara, Shunsuke Ishii, Takahiro Okumura, Toru Hashimoto, Mitsuhiro Fukata, Tohru Minamino, Aileen Raizner, Yi Chen, Yasushi Otsuka, Michele F. Mercuri, Masatoshi Minamisawa, Yukio Ando

https://doi.org/10.1253/circrep.CR-26-0013

Impact of Radiation Therapy on Diastolic Function and Cardiac Troponin I Levels in Cancer Patients Undergoing Contemporary Radiotherapy

Fumika Haga, Masayoshi Oikawa, Tetsuya Tani, Tetsuro Yokokawa, Shunsuke Miura, Tomofumi Misaka, Takashi Kaneshiro, Akiomi Yoshihisa, Takafumi Ishida, Yasuchika Takeishi

https://doi.org/10.1253/circrep.CR-26-0026

Research Letter

Incidence of Hypotension and Clinical Characteristics After the Introduction of Angiotensin Receptor-Neprilysin Inhibitors in Patients With Acute Decompensated Heart Failure ― Effects on Cardiac Rehabilitation ―

Kaori Ando, Kengo Obata, Soichiro Fuke, Ryota Matsuzawa, Akira Tamaki

https://doi.org/10.1253/circrep.CR-26-0016

Efficacy of Acoramidis in Adults With Transthyretin Amyloid Cardiomyopathy ― Propensity Score Comparison Between a Single-Arm Open-Label Phase 3 Trial in Japan and a Global Double-Blind Phase 3 Trial ―

Nobuhiro Tahara, Aileen Raizner, Yi Chen, Michele F. Mercuri, Masatoshi Minamisawa, on behalf of the Phase 3 Japan Study Investigators

https://doi.org/10.1253/circrep.CR-25-0304

Research Letter

Tooth Count and Prognosis in Older Patients With Heart Failure

Koji Matsuo, Kikka Kobayashi, Daiki Onoda, Kazuhiro Mibu, Seiji Tamiya

https://doi.org/10.1253/circrep.CR-26-0025

Daily Digital Device Use and eHealth Literacy Among Hospitalized Older Adults With Heart Failure ― A Multicenter Cohort Study ―

Shingo Koyama, Iwao Kojima, Yuki Kimura, Hiroaki Asada, Jinshiro Saito, Ryota Yokoyama, Takuma Kawashima, Satoru Yoshioka, Toshiaki Sakakibara, Keisuke Takada, Yosuke Sugita, Misa Miura, Satoshi Sakai

https://doi.org/10.1253/circrep.CR-25-0330

Acute Decompensated Heart Failure Complicated by Ischemic Stroke and Its Association With Hemoglobin Levels

Yusuke Yamazaki, Yasuyuki Shiraishi, Shun Kohsaka, Shogo Ikegami, Takashi Kohno, Yuji Nagatomo, Mitsunobu Kitamura, Munehisa Sakamoto, Michiru Nomoto, Toshiyuki Takahashi, Masatake Kobayashi, Satoshi Higuchi, Masaki Ieda, Tsutomu Yoshikawa, for the West Tokyo Heart Failure Registry Investigators

https://doi.org/10.1253/circrep.CR-26-0015

Impact of Low Vision on Wound Healing in Patients With Chronic Limb-Threatening Ischemia

Eiji Karashima, Keiichiro Kishikawa, Shioto Yasuda, Takeo Kaneko

https://doi.org/10.1253/circrep.CR-25-0327

Relationship of Depression With Incident Cardiovascular Disease in Individuals With Chronic Kidney Disease

Daiki Kuroyanagi, Hidehiro Kaneko, Yuta Suzuki, Akira Okada, Hiroyuki Morita, Norifumi Takeda, Katsuhito Fujiu, Kaoruko Komuro, Toshiyuki Ko, Ryunosuke Mitsuno, Takashin Nakayama, Tatsuhiko Azegami, Kaori Hayashi, Hideo Yasunaga, Norihiko Takeda, Akio Kawamura

https://doi.org/10.1253/circrep.CR-25-0262

Recurrence of Takotsubo Syndrome ― Incidence and Clinical Characteristics ―

Yuki Nishimura, Junya Komatsu, Hiroki Nakayama, Hiroki Sugane, Hayato Hosoda, Ryu-ichiro Imai, Yoko Nakaoka, Koji Nishida, Shinji Mito, Shu-ichi Seki, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Sho-ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi

https://doi.org/10.1253/circrep.CR-25-0211

Association Between Severe Aortic Stenosis and Amyloid Deposition in the Myocardium of Patients With Wild-Type Transthyretin Cardiac Amyloidosis

Kentaro Furukawa, Hiroaki Kawano, Ryohei Akashi, Chisa Eguchi, Tomohiro Honda, Tadatomo Fukushima, Yusuke Takenaka, Masamichi Eguchi, Tsuyoshi Yoshimuta, Takashi Kudo, Masahiro Nakashima, Mitsuharu Ueda, Satoshi Ikeda, Koji Maemura

https://doi.org/10.1253/circrep.CR-26-0014

Machine Learning Models Incorporating Nursing Care Needs to Predict 180-Day Prognosis in Patients With Heart Failure ― Validation With Discrimination and Calibration Analyses ―

Takuya Nishino, Katsuhito Kato, Shuhei Tara, Daisuke Hayashi, Tomohisa Seki, Toru Takiguchi, Yoshiaki Kubota, Takeshi Yamamoto, Mitsunori Maruyama, Eitaro Kodani, Nobuaki Kobayashi, Akihiro Shirakabe, Toshiaki Otsuka, Shoji Yokobori, Yukihiro Kondo, Kuniya Asai

https://doi.org/10.1253/circrep.CR-25-0337

Effect of Comprehensive Outpatient Cardiac Rehabilitation on All-Cause Mortality After Transcatheter Aortic Valve Implantation

Daichi Kobayashi, Masakazu Saitoh, Kentaro Hori, Shinya Tajima, Kotaro Takizawa, Junko Sakamoto, Atsuko Nakayama

https://doi.org/10.1253/circrep.CR-25-0341

Research Letter

Exploratory Evaluation of Multidisciplinary Collaboration in Developing a Community-Based Heart Failure Care System

Yuka Odate, Yuki Nakano, Mayumi Nagasaka, Yukiko Hirose, Misao Suzuki, Saori Fujii, Kumiko Toshinskiy, Naomi Yaguchi, Tsuyoshi Ono

https://doi.org/10.1253/circrep.CR-26-0012

Association Between Locomotive Syndrome and N-Terminal Pro B-Type Natriuretic Peptide Concentration in a Health Screening Cohort ― A Retrospective Cross-Sectional Study ―

Chiaki Mizuno, Hiroaki Hiraiwa, Shinya Yokoyama, Takanori Ito, Kazuki Sahara, Takashi Honda,
Taku Tanaka, Tetsuhito Kojima, Naoyoshi Kariya, Ryota Ito, Shingo Kazama, Toru Kondo, Ryota Morimoto, Hiroki Kawashima, Toyoaki Murohara

https://doi.org/10.1253/circrep.CR-25-0323

Relationship Between Post-Procedural Angiography-Derived Index of Microcirculatory Resistance and Periprocedural Myocardial Injury After Percutaneous Coronary Intervention

Tetsuya Matsuyama, Takayuki Okamura, Tatsuhiro Fujimura, Yosuke Miyazaki, Takeshi Suetomi, Hideaki Akase, Yuki Nakata, Keita Kaneyuki, Motoaki Sano

https://doi.org/10.1253/circrep.CR-26-0006

Refining the Cardiovascular?Kidney?Metabolic Staging System for Improved Risk Stratification of Chronic Kidney Disease Progression in Type 2 Diabetes

Tomohito Gohda, Nozomu Kamei, Marenao Tanaka, Masato Furuhashi, Tatsuya Sato, Mitsunobu Kubota, Michiyoshi Sanuki, Yasuhiko Tomino, Yusuke Suzuki, Maki Murakoshi

https://doi.org/10.1253/circrep.CR-25-0345

Impaired Atrial Natriuretic Peptide Secretion as a Marker of Advanced Atrial Fibrillation

Satoshi Oka, Koji Miyamoto, Chisa Asahina, Toshihiro Nakamura, Akinori Wakamiya, Nobuhiko Ueda, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Yuko Inoue, Takeshi Aiba, Kengo Kusano

https://doi.org/10.1253/circrep.CR-25-0340

Association Between Outpatient Cardiac Rehabilitation and Falls in Older Patients With Cardiovascular Disease ― A 1-Year Longitudinal Study ―

Kohei Shiota, Masakazu Saitoh, Kotaro Iwatsu, Tomoyuki Morisawa, Tetsuya Takahashi, Junya Nishimura, Masamichi Mochizuki, Eriko Kitahara, Toshiyuki Fujiwara, Miho Yokoyama, Tohru Minamino

https://doi.org/10.1253/circrep.CR-25-0267

Research Letter

Clinical Factors Associated With Positive 99 mTc-Pyrophosphate Scintigraphy Beyond Kumamoto Criteria in a Real-World Cohort

Rie Aoyama, Tatsuki Ugawa, Shinichi Okino, Shigeru Fukuzawa

https://doi.org/10.1253/circrep.CR-26-0005

Evaluation of Exercise Tolerance in Cancer Patients With Cardiovascular Complications ― A Japanese Single-Center Retrospective Study Using Cardiopulmonary Exercise Testing ―

Asaki Saijo, Hidetaka Itoh, Yuko Tanabe, Chinatsu Komiyama, Ayako Harima, Tetsuo Yamaguchi, Yasuhiro Tomita, Yuji Miura, Takahide Kodama

https://doi.org/10.1253/circrep.CR-25-0331

Clinical Impact of the ‘Delta-Aortic Valve Gradient’, the Reduction in the Mean Aortic Valve Pressure Gradient After Transcatheter Aortic Valve Implantation, on Left Ventricular Ejection Fraction Improvement and Long-Term Mortality in Patients With Severe Aortic Stenosis and Left Ventricular Dysfunction

Naoto Murakami, Kenichi Ishizu, Masaomi Hayashi, Shinichi Shirai

https://doi.org/10.1253/circrep.CR-25-0227

Effect of Mitochondrial Ca2+ Uptake on Arrhythmogenesis in Right Ventricular Hypertrophy in Rats and Mice

Haruka Sato, Kazunori Kumasaka, Yuka Someya, Yui Takahashi, Shiori Akazawa, Kao Takeda, Sana Koyama, Tsuyoshi Okumura, Masahito Miura

Targeting Nuclear Factor-κB1 With Andrographolide ― Novel Strategy to Inhibit Vascular Lesions and Aneurysm Formation in Abdominal Aortic Aneurysm ―

Ying Wen, Xing Fu, Zheng Chen, Jianxiang Wang, Yingying Liu, Yixian Ren, Zefeng Lin, Luhao Liu, Wai Ho Tang

Small Dense Low-Density Lipoprotein Cholesterol Predicts Long-Term Coronary Artery Disease Recurrence in Patients Without Metabolic Dyslipidemia

Shinji Koba, Yuya Yokota, Noriyuki Satoh, Yasuki Ito, Fumiyoshi Tsunoda, Koshiro Sakai, Yuya Nakamura, Makoto Shoji, Tsutomu Hirano, Toshiro Shinke

Bisoprolol vs. Carvedilol After Percutaneous Coronary Intervention in Acute Myocardial Infarction With Reduced Left Ventricular Ejection Fraction

Jun-Chang Jeong, Jong-Il Park, Kang-Un Choi, Jong-Ho Nam, Chan-Hee Lee, Jang-Won Son, Jong-Seon Park, Jang-Hoon Lee, Seung-Ho Hur, Kyeong-Ho Yun, Hyo-Soo Kim, Ju-Han Kim, Youngkeun Ahn, Myung-Ho Jeong, Ung Kim, on behalf of the KAMIR-V Registry Investigators

Optimizing Single-Lead Electrocardiogram Orientation Improves Detection of Left Ventricular Dysfunction

Hisaki Makimoto, Takayuki Okatani, Masafumi Sato, Shinnosuke Sawano, Satoshi Kodera, Kenji Harada, Kazunori Anno, Tomoyuki Kabutoya, Masashi Kamioka, Tomonori Watanabe, Hiroaki Watanabe, Takahiro Komori, Ayako Yokota, Yasushi Imai, Yukiyo Ogata, Takahide Kohro, Norihiko Takeda, Tetsuya Matoba, Ryozo Nagai, Kazuomi Kario

Research Letter

Association of Lipid Core Burden Index With Early Progression of Cardiac Allograft Vasculopathy in Patients After Heart Transplantation

Kenta Otsuka, Sakae Takenaka, Toshiyuki Nagai, Takuma Sato, Takao Konishi, Atsushi Tada, Takeshi Hamaya, Yuki Mori, Akinori Takahashi, Sou Sasaki, Kento Tamano, Toshifumi Tamura, Sho Kazui, Yutaro Yasui, Yuta Kobayashi, Taro Temma, Kiwamu Kamiya, Satoru Wakasa, Toshihisa Anzai

E2F5 Promotes Vascular Endothelial Cell Proliferation and Angiogenesis in Diabetic Lower Limb Ischemia via an Autophagy-Related Mechanism

Yuyan Zhan, Hongwei Shi, Xiaoying Miu, Xiaoping Peng, Jungang Nie, Dong Liu, Qiong Duan, Ting Kang

Research Letter

Association Between Ventricular?Arterial Coupling and C-Reactive Protein in Patients at Risk for Heart Failure

Yasuyoshi Takei, Hirofumi Tomiyama, Akira Yamashina, Yukihito Higashi, Kazuhiro Satomi

Research Letter

Prevalence and Clinical Characteristics of Patients With Heart Failure With Preserved Ejection Fraction Who Meet the Obesity-Related Eligibility Criteria for Subcutaneous Incretin Receptor Agonists in Japan ― Insights From the PARACLETE Study ―

Ken Nishikawa, Sho Suzuki, Masatoshi Minamisawa, Akane Yamakawa, Shinya Hiramitsu, Katsuya Onishi, Dai Yumino, Kenji Shiino, Tomoya Ueda, Atsuhiko Kawamoto, Masato Kasahara, Shungo Hikoso, Koichiro Kuwahara, Yoshihiko Saito

Contribution of Non-Sustained Ventricular Tachycardia to the Primary Prevention of Sudden Cardiac Death ― Validation of Current Japanese Circulation Society / Japanese Heart Rhythm Society Guideline Recommendations in the Nippon Storm Study ―

Ryobun Yasuoka, Masahiro Maruyama, Takashi Noda, Gaku Nakazawa, Takashi Nitta, Yoshifusa Aizawa, Tohru Ohe, Takashi Kurita, Nippon Storm Investigators

Research Letter

Time-Dependent Analysis of Blood Sampling to Detect Metabolic Ischemia ― Serial Coronary Artery?Coronary Sinus Lactate Analysis During Acetylcholine Provocation ―

Tsuyoshi Ito, Masashi Yokoi, Shuichi Kitada, Yu Kawada, Tatsuya Mizoguchi, Sayuri Yamabe, Atsushi Niwa, Toshihiko Goto, Yoshihiro Seo

Prognostic Impact of Quantitative Flow Ratio-Derived Physiology for Intermediate Non-Infarct-Related Artery in Acute Myocardial Infarction

Sho Nakao, Takayuki Ishihara, Takuya Tsujimura, Yosuke Hata, Masaya Kusuda, Wataru Ariyasu, Subaru Fujii, Toshiaki Mano

Vascular Biology and Vascular Medicine

Review Article

Association Between Chronic Inflammation and Cardiovascular Disease ― Focus on High-Sensitivity C-Reactive Protein ―

Tomoya Hara, Masataka Sata

Two Faces of Cardiovascular Actions of Testosterone Dependent on the Presence or Absence of Nitric Oxide Synthases in Mice

Shotaro Higa, Mayuko Sakanashi, Masato Tsutsui, Takashi Tasaki, Akihide Tanimoto, Yuji Taira, Hiroaki Shimokawa, Yukio Kuniyoshi, Kojiro Furukawa

Prognostic Value of the Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio for Cardiovascular Events in Statin-Treated Type 2 Diabetes With Diabetic Retinopathy Without Prior Cardiovascular Disease

Hiroka Nakashima, Shota Ikeda, Keisuke Shinohara, Sho Matsumoto, Daisuke Yoshida, Ryosuke Nakashima, Yoshiyasu Ono, Ryohei Miyamoto, Ayano Hara, Shouji Matsushima, Toru Hashimoto, Takeo Fujino, Kayo Misumi, Shunsuke Katsuki, Keimei Yoshida, Junji Kishimoto, Hiroshi Itoh, Issei Komuro, Hiroyuki Tsutsui, Kohtaro Abe

High Human Epididymis Protein 4 Levels Are Associated With Lower Systolic Function and Poor Prognosis in Heart Failure With Reduced Ejection Fraction

Yuki Okuno, Shinsuke Hanatani, Fumihiko Ogata, Shinpei Yamaguchi, Masahiro Yamamoto, Naoto Kuyama, Masanobu Ishii, Hiroki Usuku, Eiichiro Yamamoto, Seitaro Oda, Yasuhiro Izumiya, Hirofumi Soejima, Hiroaki Kawano, Toshinori Hirai, Kenichi Tsujita

Height- and Body Mass Index-Based Sarcopenia ― Prognostic and Functional Implications in Older Patients Hospitalized for Heart Failure ―

Yuta Ozaki, Yusuke Uemura, Shigefumi Honda, Toru Kondo, Shingo Kazama, Kenji Takemoto, Masato Watarai, Toyoaki Murohara

Tenascin-C and Fibrosis as Prognostic Predictors of　Peripartum Cardiomyopathy　― A Histopathological Study ―

Kisaki Amemiya, Junko Nakashima, Keiko Ohta-Ogo, Hatsue Ishibashi-Ueda, Manabu Matsumoto, Yoshihiko Ikeda, Yoshiaki Morita, Yasumasa Tsukamoto, Jun Yoshimatsu, Kinta Hatakeyama, Chizuko Aoki-Kamiya

Changes in Natriuretic Peptide Levels and Cardiac Structure in Patients Treated With Vericiguat ― VERIFY-HF Registry ―

Kenji Kanenawa, Kenji Ando, Takahito Nasu, Wataru Fujimoto, Nobuyuki Kagiyama, Yasuyuki Shiraishi, Shunsuke Ishii, Takeshi Ijichi, Gaku Nakazawa, Koshiro Kanaoka, Shingo Matsumoto, VERIFY-HF Investigators

Cathelicidin Links Visceral Fat Accumulation and Coronary Artery Disease

Motoki Taniguchi, Akira Taruya, Chie Kitahara, Shingo Ota, Takashi Kato, Yuki Desaki, Izumi Sasaki, Yosuke Katayama, Teruaki Wada, Masahiro Takahata, Keisuke Satogami, Yuichi Ozaki, Manabu Kashiwagi, Yasutsugu Shiono, Kentaro Honda, Takashi Yamano, Kazushi Takemoto, Akio Kuroi, Hironori Kitabata, Hiroaki Hemmi, Takaaki Matsuoka, Yoshiharu Nishimura, Atsushi Tanaka

Vascular Biology and Vascular Medicine

Diagnostic Ability of the Japanese Version of the High Bleeding Risk Criteria in Patients With Lower Extremity Peripheral Arterial Disease

Tadahiro Matsumoto, Yuichi Saito, Yuji Ohno, Kayo Yamamoto, Norikiyo Oka, Masayuki Takahara, Sakuramaru Suzuki, Raita Uchiyama, Masahiro Suzuki, Yo Iwata, Satoru Kobayashi, Yoshio Kobayashi

Assessment of and Factors Contributing to Adequate Endothelization After Drug-Eluting Stent Implantation

Masami Nishino, Yasuyuki Egami, Hiroaki Nohara, Shodai Kawanami, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano, Tatsuya Shiraki, Daisuke Nakamura, Isamu Mizote, Takayuki Ishihara, Toshiaki Mano, Takahisa Yamada, Naoki Itaya, Takaharu Nakayoshi, Takafumi Ueno, Daisaku Nakatani, Shungo Hikoso, Shinsuke Nanto, Yasushi Sakata

A Phase 2, Randomized, Clinical Trial of Inhaled Nitric Oxide for Acute Severe Right Heart Failure With Pulmonary Hypertension (PHiNO Study)

Takeshi Ogo, Jin Ueda, Akihiro Tsuji, Ryotaro Asano, Hiroya Hayashi, Ryo Takano, Shinya Fujisaki, Koko Asakura, Haruko Yamamoto

Impact of Genetic Testing Among Patients With Familial Hypercholesterolemia on Adverse Cardiovascular Events ― The Hokuriku-Plus Familial Hypercholesterolemia Registry Study ―

Hayato Tada, Yasuaki Takeji, Chiaki Goten, Hirofumi Okada, Shohei Yoshida, Masaya Shimojima, Akihiro Nomura, Mika Mori, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Noboru Fujino, Katsuhiko Nagase,Masa-aki Kawashiri, Masayuki Takamura, on behalf of the Hokuriku-plus Familial Hypercholesterolemia Registry Study Group

Apple Watch-Guided Anticoagulation After Atrial Fibrillation Ablation ― The Up to AF Trial ―

Akihiro Sunaga, Nobuaki Tanaka, Yasuyuki Egami, Hitoshi Minamiguchi, Masato Kawasaki, Takafumi Oka, Koichi Inoue, Masaharu Masuda, Miwa Miyoshi, Nobuhiko Makino, Yuko Hirao, Masamichi Yano, Takashi Kanda, Tetsuya Watanabe, Takayuki Sekihara, Tatsuhisa Ozaki, Daisaku Nakatani, Katsuki Okada, Hirota Kida, Yuki Matsuoka, Daisuke Sakamoto, Tomomi Yamada, Yohei Sotomi, Yasushi Sakata, on behalf of the OCVC-Arrhythmia Investigators

Review Article

Cardiovascular, Kidney, and Metabolic Network Medicine ― Past, Present, and Future Challenges and Directions ―

JCS 2026 Guideline on the Management of Infective Endocarditis

Chisato Izumi, Masao Daimon, Shuichiro Kaji, Akiko Masumoto, Kyomi Ashihara, Masashi Amano, Shiro Uemura, Hideki Ota, Takahiro Ohara, Kenji Okada, Takayuki Kawamura, Masahiko Goya, Masatoshi Koga, Jiro Sakamoto, Tetsu Sakamoto, Hiroshi Sasano, Masayuki Shiozawa, Taro Shimizu, Jun Takahashi, Kazuhiko Nakano, Ryota Nomura, Kazuki Hisatomi, Kenji Fukushima, Soichiro Henmi, Takashi Miura, Kotaro Mitsutake, Tomoyuki Miyamoto, Tomoaki Murakami, Hirotsugu Yamada, Ken-ichi Yanagida, Go Yamamoto, Daisuke Yoshioka, Yutaka Otsuji, Hiroaki Kitaoka, Toshimi Kimura, Akira Shiose, Satoshi Nakatani, on behalf of the Japanese Circulation Society Joint Working Group

JCS 2026 Guideline on Management of Large Vessel Vasculitis

Yoshikazu Nakaoka, Yoshiko Watanabe, Takahiko Sugihara, Kenji Nagasaka, Naoto Tamura, Hajime Yoshifuji, Nobuyuki Yajima, Fumika Aono, Takuya Hashimoto, Akihiro Ishizu, Tomohiro Iida, Tomonori Ishii, Takatoyo Kiko, Yasuhiro Maejima, Takako Miyamae, Yu Nakano, Toshihiro Nanki, Hiroaki Niiro, Hideki Ota, Noriko Okochi, Ken-ei Sada, Kunihiro Shigematsu, Haruhito A. Uchida, Yoshiyuki Abe, Chizuko Aoki-Kamiya, Yoh Arita, Takaya Handa, Ryosuke Hiwa, Manabu Honda, Ryuhei Ishihara, Jun Ishizaki, Shuichi Ito, Toru Iwahashi, Naomi Iwata, Keiichiro Kadoba, Yuji Kamiyama, Mai Kawazoe, Takashi Kida, Genki Kidoguchi, Daisuke Kobayashi, Kazuhiro Kobayashi, Atsushi Kurata, ... on behalf of the Japanese Circulation Society Joint Working Group

Research Letter

Baseline Prolonged QRS Duration May Predict In-Hospital Outcomes of Patients With Acute Myocarditis ― Multicenter Observational Study ―

Ayano Yoshida, Takuma Takada, Eiji Shibahashi, Takuro Abe, Kensuke Shimazaki, Takanori Kawamoto, Motoko Kametani, Natsuko Satomi, Kazuho Kamishima, Takashi Saito, Erina Tomari, Atsushi Honda, Atsushi Takagi, Kyomi Ashihara, Junichi Yamaguchi, Kentaro Jujo

https://doi.org/10.1253/circrep.CR-25-0306

Clinical Impact of Drug-Coated Balloon-Based Percutaneous Coronary Intervention in Coronary Artery Disease Patients With Chronic Heart Failure

Tetsuya Takahashi, Taiga Ishigaki, Wataru Katawaki, Taku Toshima, Yu Kumagai, Tamon Yamanaka, Masafumi Watanabe

https://doi.org/10.1253/circrep.CR-25-0320

Short-Term Outcomes of Intra-Aortic Balloon Pump vs. Microaxial Flow Pump for Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation

Saeko Iikura, Yuki Ikeda, Shohei Nakahara, Yuki Watanabe, Yosuke Haruki, Yu Takigami, Yuko Eda, Yuichiro Iida, Takeru Nabeta, Shunsuke Ishii, Junya Ako

https://doi.org/10.1253/circrep.CR-25-0283

Research Letter

Comparison of Landiolol and Verapamil for Postoperative Atrial Fibrillation ― A Prospective Randomized Study ―

Naoto Yabu, Tomoyuki Minami, Shota Yasuda, Yoshiyuki Kobayashi, Aya Saito

https://doi.org/10.1253/circrep.CR-25-0335

Preoperative Sarcopenia and Postoperative Activities of Daily Living Decline in Patients Undergoing Elective Cardiovascular Surgery

Tomohiro Kato, Yuta Ozaki, Shigefumi Honda, Yusuke Uemura, Kenji Takemoto, Masato Watarai, Toyoaki Murohara

https://doi.org/10.1253/circrep.CR-25-0299

Long-Term Efficacy of Drug-Coated Balloon Angioplasty vs. Drug-Eluting Stent for De Novo Large-Vessel Coronary Arteries

Mayuka Masuda, Hiroyuki Yamamoto, Shinsuke Nakano, Nobuyuki Takahashi, Taishi Miyata, Tomohiro Inoue, Tomofumi Takaya

https://doi.org/10.1253/circrep.CR-25-0322

Admission Renal Dysfunction Severity as a Prognostic Factor in Older Patients With Acute Heart Failure

Kazuya Kito, Masakazu Saitoh, Yuji Mori, Keita Fujiyama, Masahiro Toda, Kotaro Iwatsu, Tomoyuki Morisawa, Tetsuya Takahashi, Michitaka Kato

https://doi.org/10.1253/circrep.CR-25-0274

Review Article

Pulsed Field Ablation for Atrial Fibrillation in Japan ― Current Status and Future Perspectives ―

https://doi.org/10.1253/circrep.CR-25-0284

Left vs. Normal QRS Axis During Left Bundle Branch Block Induced by Transcatheter Aortic Valve Replacement ― 3-Year Outcomes ―

Kenichi Sasaki, Shingo Kuwata, Masaki Izumo, Yukio Sato, Takahiko Kai, Taishi Okuno, Tetsu Tanaka, Masahiro Sekiguchi, Yoshihiro J. Akashi

https://doi.org/10.1253/circrep.CR-25-0249

Impact of Plaque Morphology on Drug-Coated Balloon Treatment Outcomes for Coronary Calcified Lesions ― An Optical Coherence Tomography Analysis ―

Masahiro Koide, Kan Zen, Tomotsugu Seki, Kento Fukui, Kazuaki Takamatsu, Jun Shiraishi, Satoaki Matoba

https://doi.org/10.1253/circrep.CR-25-0219

Research Letter

Association Between Symptom Characteristics, Knowledge Sources, and Patient Interpretation of Acute Coronary Syndrome ― Insights From the Japanese Circulation Society Chest Pain Registry ―

Masato Uchida, Satoshi Yoshimura, Kanna Arimoto, Hirotoshi Nishikita, Yohei Fushimura, Hirokazu Yokoi, Takuya Taniguchi, Chika Nishiyama, Yasunori Ueda, Taku Iwami, on behalf of the Education and Implementation for Cardiac Emergency Committee of the Japanese Circulation Society

https://doi.org/10.1253/circrep.CR-25-0301

Research Letter

From Working to Retirement-Age ― How Sleep Duration Is Related to Atrial Fibrillation Using 1-Week Holter-Electrocardiogram With Accelerometry ―

Tadashi Hoshiyama, Kenichi Tsujita, Yuko Inoue, Masanobu Ishii, Koichiro Kumagai, Takahisa Noma, Kenzaburo Nakajima, Yoshihiro Kokubo, Masatoshi Koga, Naoki Mochizuki, Hisao Ogawa, Kengo Kusano

https://doi.org/10.1253/circrep.CR-25-0310

Association of Geographical Distance and Residential Population Density With Clinical Outcomes in Acute Decompensated Heart Failure ― Insights From the Kyoto Congestive Heart Failure (KCHF) Registry ―

Erika Yamamoto, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Yusuke Yoshikawa, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Ryusuke Nishikawa, Kazushige Kadota, Yutaka Furukawa, Kenji Ando, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura, Koh Ono, on behalf of the KCHF Study Investigators

https://doi.org/10.1253/circrep.CR-25-0316

Protocol Paper

Development and Internal Validation of Machine-Learning Models for Short-Term Prediction of Day-to-Day Home Blood Pressure Variability Using IoT-Based Environmental and Activity Data ― Protocol for the AURA-BPV Study ―

Yoko M. Nakao, Atsushi Takayama, Koji Kawakami

https://doi.org/10.1253/circrep.CR-25-0314

Sex-Based Differences in the Effect of Short Dual Antiplatelet Therapy Followed by Prasugrel Monotherapy in High-Bleeding-Risk Patients After Percutaneous Coronary Intervention

Norihiro Kogame, Yoshihisa Nakagawa, Ken Kozuma, Raisuke Iijima, Anna Tsutsui, Yoshitaka Murakami, Masayuki Fukuzawa, Satoru Abe, Go Kato, Masato Nakamura

https://doi.org/10.1253/circrep.CR-25-0298

Initial Outcomes After Trans-Right Subclavian Transcatheter Aortic Valve Implantation ― Analysis of Device Coaxiality ―

Ryusuke Hamada, Kyohei Onishi, Masakazu Yasuda, Kosuke Fujita, Naoko Soejima, Tatsuya Miyoshi, Koichiro Matsumura, Shinsuke Kotani, Atsunori Okamura, Yoshitaka Iwanaga, Genichi Sakaguchi, Gaku Nakazawa

https://doi.org/10.1253/circrep.CR-25-0243

Mid-Term Clinical Outcomes and Hemodynamic Performance of 19-mm Bioprostheses Following Aortic Valve Replacement ― A Single-Institution 10-Year Experience ―

Takayuki Gyoten, Yuta Kanazawa, Yu Kumagai, Takayuki Akatsu, Yuko Gatate, Takahide Arai, Shintaro Nakano, Akihiro Yoshitake

https://doi.org/10.1253/circrep.CR-25-0307

Impact of Preoperative Malnutrition and Sarcopenia on Clinical Outcomes After Transcatheter Aortic Valve Replacement

Kanna Nakamura, Tomohiko Taniguchi, Aoi Omori, Hirotoshi Nishi, Gakuto Bando, Makoto Idouji, Tsukasa Motoyoshi, Madoka Sano, Yuta Azumi, Ryosuke Murai, Junichi Ooka, Taiji Okada, Toshiaki Toyota, Yasuhiro Sasaki, Kitae Kim, Atsushi Kobori, Natsuhiko Ehara, Makoto Kinoshita, Yutaka Furukawa

https://doi.org/10.1253/circrep.CR-25-0281

Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on Infective Endocarditis Outcomes in Japan ― A Nationwide Observational Study ―

Takahiro Kuno, Yoshiaki Ohyama, Yoko Sumita, Koshiro Kanaoka, Yoshihiro Miyamoto, Hideki Ishii

https://doi.org/10.1253/circrep.CR-25-0232

Research Letter

Clinical Characteristics of Cardiovascular Disease Patients With Dynapenia and the Effects of Outpatient Physical Therapy

Keisuke Okano, Kouki Sano, Yo Mukai, Yusuke Seto, Ritsu Nisimura, Tetsuya Takahashi, Hideki Saito

https://doi.org/10.1253/circrep.CR-25-0305

Impact of Pre-Existing Cardiovascular and Metabolic Conditions on the Development of Heart Failure After Paclitaxel Therapy ― Real-World Study Based on a Nationwide Claims Database in Japan ―

Shiori Iwane, Masayuki Tanaka, Tomoyoshi Miyamoto, Kentaro Nishida, Shigeru Hasebe, Maho Kikuta, Toshikazu Tsuji

https://doi.org/10.1253/circrep.CR-25-0208

Risk Factors for Venous Thromboembolism in Advanced Non-Small Cell Lung Cancer ― A Nationwide Administrative Database Study ―

Tetsuya Kimura, Yugo Yamashita, Yasutaka Ihara, Megumi Mizutani, Ryota Kawai, Ayumi Shintani

https://doi.org/10.1253/circrep.CR-25-0167

Aspirin vs. Clopidogrel Monotherapy Beyond 1 Month After Percutaneous Coronary Intervention in Patients With Diabetes ― Prespecified Subgroup Analysis of the STOPDAPT-3 Trial ―

Kenji Kanenawa, Ko Yamamoto, Takenori Domei, Masahiro Natsuaki, Hirotoshi Watanabe, Takeshi Morimoto, Yuki Obayashi, Ryusuke Nishikawa, Tomoya Kimura, Kenji Ando, Satoru Suwa, Tsuyoshi Isawa, Hiroyuki Takenaka, Tetsuya Ishikawa, Minoru Yamada, Tetsuzo Wakatsuki, Yoichi Nozaki, Hideki Kitahara, Ryuichi Kato, Ryoma Kawai, Yohei Kobayashi, Mitsuru Ishii, Yoshitaka Goto, Koh Ono, Takeshi Kimura, on behalf of the STOPDAPT-3 Investigators

Monocyte Immunometabolic Axis Linking Type 2 Diabetes to Coronary Artery Disease Revealed by Multi-Omics Integration and Mendelian Randomization

Min Zhai, Feng Bai, Rui Yan, Min Liu

Prognostic Impact of COVID-19 on Patients With Acute Coronary Syndrome Undergoing Emergent Percutaneous Coronary Intervention ― Insights From the J-PCI Nationwide Registry ―

Yoshihisa Kanaji, Kyohei Yamaji, Ayako Kunimura, Eisuke Usui, Tatsuhiro Nagamine, Hiroki Ueno,
Mirei Setoguchi, Kodai Sayama, Hikaru Shimosato, Takahiro Watanabe, Takashi Mineo, Taishi Yonetsu, Yuichiro Mori, Shun Kohsaka, Hideki Ishii, Tetsuya Amano, Ken Kozuma, Tsunekazu Kakuta

Prognostic Value of Serum Lipoprotein(a) Levels in Japanese Patients With ST-Segment Elevation Myocardial Infarction

Keiko Nishiyama, Kensaku Nishihira, Michikazu Nakai, Kensho Baba, Makoto Takamatsu, Yasuhiro Honda, Keisuke Yamamoto, Shun Nishino, Kosuke Kadooka, Takeaki Kudo, Kenji Ogata, Toshiyuki Kimura, Nehiro Kuriyama, Yoshisato Shibata

Research Letter

Seven-Day Holter Monitoring Substantially Improves Detection of Low-Burden Atrial Fibrillation
― Results From a Large Japanese Multicenter Cohort ―

Yuko Inoue, Kota Nakatsuji, Koichiro Kumagai, Tadashi Hoshiyama, Kenichi Tsujita, Takahisa Noma, Yoshihiro Kokubo, Masatoshi Koga, Naoki Mochizuki, Hisao Ogawa, Kengo Kusano

Comparison of Atheroma Burden Changes Using Conventional vs. End-Diastolic Intravascular Ultrasound Segmentation ― Post Hoc Analysis of the PACMAN-AMI Study ―

Nathan Angelo Lecaros Yap, Christos V. Bourantas, Sylvain Losdat, Nathaniel Yu Jian Ng, Jonas H?ner, Ibrahim Halil Tanboga, Tatsuhiko Otsuka, Yasushi Ueki, Andreas Baumbach, Anthony Mathur, Ryota Kakizaki, Ernest Spitzer, Jouke Dijkstra, Thomas Engstr?m, David Spirk, Irene Lang, Konstantinos C. Koskinas, Lorenz R?ber

Linear and Nonlinear Associations Between Lipoprotein(a) and the Risks of Atherosclerotic Cardiovascular Disease

Hsin-Yin Hsu, Hsien-Yu Fan, Ming-Chieh Tsai, Chih-Jun Lai, Lee-Ching Hwang, Kuo-Liong Chien

Ischemic and Bleeding Events After Early Initiation of Direct Oral Anticoagulants for Acute Intracranial Hemorrhage With Non-Valvular Atrial Fibrillation ― A Multicenter Prospective Registry ―

Masatoshi Koga, Kazunori Toyoda, Yasuyuki Iguchi, Ryo Itabashi, Hiroharu Kataoka, Michikazu Nakai, Kanta Tanaka, Kaori Miwa, Rei Kondo, Tatemi Todaka, Naoto Kimura, Kunikazu Yoshimura, Shigeo Yamashiro, Takahiro Ogishima, Yuka Terasawa, Nobukazu Komoribayashi, Nobuyuki Sakai, Taketo Hatano, Shuji Arakawa, Kazutaka Sonoda, Joji Hagii, Teruyuki Hirano, Fumio Miyashita, Hiroyuki Ohnishi, Kazumi Kimura, Toshihiro Ueda, Keiko Maezono-Kandori, Yukako Yazawa, Masanori Kinosada, Tsuyoshi Izumo, Shouhei Noshiro, Hikaru Nagasawa, Kuniyasu Wada, Hiroshi Yamagami, Kenji Kamiyama, Yasushi Takagi, Yasuhiro Ito, Kumiko Sugio, Atsushi Takita, Tetsuya Kimura, Martin Unverdorben, Masafumi Ihara, Shigeru Fujimoto, Ashkan Shoamanesh

Review Article

Transcatheter Aortic Valve Replacement in Patients With Aortic Stenosis and Cardiogenic Shock

Hideki Kitahara, Kaoru Matsuura, Goro Matsumiya, Yoshio Kobayashi

https://doi.org/10.1253/circrep.CR-25-0286

Statement / Opinion

Significance of Prehospital 12-Lead Electrocardiogram Transmission ― Trial Utilizing an Established Smartphone Communication Application for Acute Stroke Management ―

Koji Yamaguchi, Yutaka Kawabata, Takayuki Ise, Masataka Sata

https://doi.org/10.1253/circrep.CR-25-0319

Statement / Opinion

Innovation in Atrial Fibrillation Treatment and the Paradox of Regional Disparity

Takahiro Kamihara, Shinji Kaneko, Takuya Omura, Atsuya Shimizu

https://doi.org/10.1253/circrep.CR-25-0248

Research Letter

Multiple Arterial Grafting in Hemodialysis Patients

Kohei Hachiro, Noriyuki Takashima, Kenichi Kamiya, Masahide Enomoto, Yasuo Kondo, Fumihiro Miyashita, Hodaka Wakisaka, Tomoaki Suzuki

https://doi.org/10.1253/circrep.CR-25-0302

Protocol Paper

Clinical Trial on the Usefulness of an Intensive Low-Density Lipoprotein Cholesterol Treatment and Familial Hypercholesterolemia Screening Clinical Pathway for Acute Coronary Syndrome: The Hokuriku-plus Acute Coronary Syndrome Registry Study ― Rationale and Study Design ―

Hayato Tada, Yasuaki Takeji, Chiaki Goten, Oto Inoue, Hirofumi Okada, Shohei Yoshida, Masaya Shimojima, Akihiro Nomura, Mika Mori, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Noboru Fujino, Tadashi Toyama, Sakae Miyagi, Katsuhiko Nagase, Eishiro Mizukoshi, Kenji Miwa, Taiji Yoshida, Toshinori Higashikata, Yoshihiro Noji, Mutsuko Takata, Kensuke Fujioka, Takuya Nakahashi, Kanichi Otowa, Yusuke Mukai, Isao Aburadani, Osamu Takatori, Keisuke Ohtani, Wataru Omi, Masayuki Takamura

https://doi.org/10.1253/circrep.CR-25-0289

Impact of Snowfall on Ambulance Response Times to Out-of-Hospital Cardiac Arrest ― Nationally-Representative Population-Based Registry Analysis, 2009?2019 ―

Hirokuni Wataki, Xerxes Tesoro Seposo, Athicha Uttajug, Toshihisa Anzai, Isao Yokota, Kayo Ueda, Naohiro Yonemoto, Yoshio Tahara, Tetsuya Matoba, Takanori Ikeda, Japanese Circulation Society with Resuscitation Science Study (JCS-ReSS) Investigators

https://doi.org/10.1253/circrep.CR-25-0129

Inspiratory Muscle Strength Is an Independent Predictor of Maximum Tongue Pressure in Patients Aged ?65 Years With Acute Heart Failure ― A Retrospective Observational Study ―

Junichi Yokota, Ren Takahashi, Yuuko Matsukawa, Keisuke Matsushima, Takeru Suzuki

https://doi.org/10.1253/circrep.CR-25-0172

Long-Term Outcomes of Primary Cardiac Tumors by Histological Subtype

Mikio Shiba, Masayuki Nishiyama, Yohei Sotomi, Yuichi Motoyama, Yasuhiro Ichibori, Masatoshi Hata, Yoshiharu Higuchi

https://doi.org/10.1253/circrep.CR-25-0234

Impact of Microvascular Spasm on Coronary Physiological Assessment ― Insights From Angiography-Derived Index of Microcirculatory Resistance ―

Hikaru Shimosato, Yoshihisa Kanaji, Eisuke Usui, Masahiro Hada, Tatsuhiro Nagamine, Hiroki Ueno, Mirei Setoguchi, Kodai Sayama, Takahiro Watanabe, Takashi Mineo, Tomoyo Sugiyama, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta

https://doi.org/10.1253/circrep.CR-25-0275

Association Between Reduction in Loop Diuretics and Heart Failure Rehospitalization After Transcatheter Aortic Valve Replacement

Koki Takegawa, Koshiro Kanaoka, Yoshitaka Iwanaga, Tetsuo Sasano, Yuichi Nishioka, Tomoya Myojin, Tatsuya Noda, Tomoaki Imamura, Yoshihiro Miyamoto

https://doi.org/10.1253/circrep.CR-25-0186

Pediatric Cardiology and Adult Congenital Heart Disease

Research Letter

Japanese Nationwide Survey of New Heart Failure Drug Prescriptions by Pediatric Cardiologists

Jun Muneuchi, Collaborators

https://doi.org/10.1253/circrep.CR-25-0282

Pancreatic Exocrine Function in Hospitalized Patients Following Acute Decompensated Heart Failure ― An Observational Cross-Sectional Study ―

Masaru Hiki, Takatoshi Kasai, Akihiro Sato, Sayaki Ishiwata, Shoichiro Yatsu, Jun Shitara, Hiroki Matsumoto, Megumi Shimizu, Azusa Murata, Takao Kato, Shoko Suda, Hiroyuki Daida

https://doi.org/10.1253/circrep.CR-25-0050

Absence of Post-Discharge Exercise Habits Predicts Functional Decline in Older Heart Failure Patients ― A 6-Month Follow-up Study ―

Tetsuya Ozawa, Tatsuro Inoue, Takashi Naruke, Ryuichi Sato, Naoshi Shimoda, Masaru Yuge

https://doi.org/10.1253/circrep.CR-25-0166

Outcomes of Thoracoscopic Left Atrial Appendage Occlusion With or Without Concomitant Thoracoscopic Ablation ― Multicenter Retrospective Registry of 567 Patients in Japan ―

Taisuke Nakayama, Hiroshi Ito, Shunsuke Sato, Seimei Kure, Gentaku Hama, Masakazu Aoki, Shinya Takahashi

https://doi.org/10.1253/circrep.CR-25-0276

Research Letter

Evaluation of the 1-Year Efficacy and Tolerability of Inclisiran in Coronary Artery Disease Patients

Shigeyasu Tsuda, Shinichiro Yamada, Akihiro Yoshida

https://doi.org/10.1253/circrep.CR-25-0279

Prevalence, Clinical Features, and Treatment Response of Chronic Thromboembolic Pulmonary Hypertension in Patients With Myeloproliferative Neoplasm

Miku Hirose, Yoshihisa Nakano, Shiro Adachi, Tomomi Sugiyama, Masahiro Yoshida, Toyoaki Murohara

https://doi.org/10.1253/circrep.CR-25-0254

Establishment of Ascertainment Methods for Cardiovascular Disease Onset in the Tohoku Medical Megabank Organization

Rieko Hatanaka, Naoki Nakaya, Sayuri Tokioka, Ippei Chiba, Taku Obara, Hirohito Metoki, Masahiro Kikuya, Kotaro Nochioka, Masatsugu Orui, Kai Susukita, Masato Takase, Ikumi Kanno, Mana Kogure, Kumi Nakaya, Mami Ishikuro, Satoshi Nagaie, Soichi Ogishima, Yohei Hamanaka, Eiichi N. Kodama, Nobuo Fuse, Shinichi Kuriyama, Atsuhi Hozawa

https://doi.org/10.1253/circrep.CR-25-0263

Research Letter

Utility of Near-Infrared Spectroscopy Intravascular Ultrasound in Predicting the Slow-Flow Phenomenon During Percutaneous Coronary Intervention in Patients With Stable Angina

Naoya Otaka, Kazuhiro Kamada, Daisuke Furukawa, Koshin Horimoto, Hidenori Matsusaka, Kunio Morishige

https://doi.org/10.1253/circrep.CR-25-0272

Clinical Determinants and Prognostic Significance of Circulating Angiopoietin-Like Protein 3 Levels in Patients With Chronic Coronary Syndrome

Hiroki Tanaka, Yunosuke Matsuura, Kinuko Yamamoto, Soichi Komaki, Masashi Yamaguchi, Kohei Moribayashi, Takeshi Ideguchi, Michikazu Nakai, Toshihiro Tsuruda, Koichi Kaikita

https://doi.org/10.1253/circrep.CR-25-0264