Date of Advance online publication

Robotic Mitral Valve Repair in Patients With Thoracic Deformity

Satoru Tomita, Takashi Kakuta, Satoshi Kainuma, Naonori Kawamoto, Kota Suzuki, Yuki Tadokoro, Hironobu Sakurai, Tomoyuki Fujita, Satsuki Fukushima

https://doi.org/10.1253/circrep.CR-26-0003

Combination of Skin Adhesives and Vascular Closure Device for Complete Hemostasis After Catheter Ablation

Yasuyuki Takada, Junichi Kamoshida, Muryo Terasawa, Kazuhiro Satomi, Yoshinao Yazaki

https://doi.org/10.1253/circrep.CR-25-0288

Early In-Hospital Functional Status Predicts Recovery at Discharge in Older Patients Hospitalized for Acute Decompensated Heart Failure

Yoshiro Tsuruta, Shuichi Kitada, Yu Kawada, Tatsuya Mizoguchi, Masashi Yokoi, Sayuri Yamabe, Kento Mori, Tsuyoshi Ito, Toshihiko Goto, Yoshihiro Seo

https://doi.org/10.1253/circrep.CR-26-0059

Characteristics and Outcomes of Multisystemic Inflammation in Patients Clinically Diagnosed With Non-COVID-19-Related Fulminant Myocarditis

Tadatomo Fukushima, Hiroaki Kawano, Shuntaro Sato, Koshiro Kanaoka, Kenji Onoue, Yoshihiko Saito, Tetsufumi Motokawa, Tomohiro Honda, Ryohei Akashi, Satoshi Ikeda, Koji Maemura

https://doi.org/10.1253/circrep.CR-26-0068

Lard Intake Reduced Tetralinoleoyl Cardiolipin and Attenuated the Cardioprotective Effects of Exercise in Mice With Pressure Overload-Induced Heart Failure

Ayano Kitamura, Hirokazu Ohminami, Airi Oshima, Mina Matsubara, Tomoki Sato, Masaki Takikawa, Kohta Ohnishi, Masashi Masuda, Hisami Yamanaka-Okumura, Shinji Miura, Yutaka Taketani

https://doi.org/10.1253/circrep.CR-25-0297

Impact of Heart Disease and Multimorbidity on Oral Frailty in Japanese Community-Dwelling Older Adults

Nobuhide Ohashi, Akira Yoshizawa, Chiaki Matsubara, Yusuke Saigusa, Jun Aida, Haruka Tohara, Yumi Chiba

https://doi.org/10.1253/circrep.CR-26-0056

Reperfusion Therapy and Outcomes in High-Risk Pulmonary Embolism ― Multicenter Registry Study From the Tokyo Cardiovascular Care Unit Network ―

Takeshi Yamamoto, Hiroyuki Yamamoto, Toshihiro Nozato, Atsushi Mizuno, Nobuhiro Hara, Shinji Hisatake, Kuniya Asai, Shun Kohsaka, Morimasa Takayama

https://doi.org/10.1253/circrep.CR-26-0060

Research Letter

Prognostic Significance of Upstroke Time per Cardiac Cycle in Coronary Artery Disease Patients With Normal Ankle-Brachial Index

Joh Akama, Takeshi Shimizu, Yuuki Muto, Yu Sato, Takatoyo Kiko, Akihiko Sato, Tomofumi Misaka, Takashi Kaneshiro, Akiomi Yoshihisa, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi

https://doi.org/10.1253/circrep.CR-26-0057

Factors Associated With Below-the-Ankle Lesions and Their Impact on Clinical Outcomes Following Revascularization in Chronic Limb-Threatening Ischemia

Tsutomu Doita, Keisuke Miyake, Taro Yamasumi, Takashi Nakamura, Shigeru Miyagawa

https://doi.org/10.1253/circrep.CR-26-0063

Impact of Delayed Initiation of Cardiovascular Physical Therapy on Prolonged Hospital Length of Stay in Patients With Heart Failure

Chisaki Heiuchi, Kenichi Kasai, Katsuyoshi Hirose, Shiho Yabu, Tatsuya Kawasaki

https://doi.org/10.1253/circrep.CR-25-0239

Prognostic Utility of Pulmonary Arterial Elastance in Patients With ST-Segment Elevation Myocardial Infarction Classified as Killip Classes 3?4

Shotaro Kawai, Kensaku Nishihira, Toshiyuki Kimura, Makoto Takamatsu, Yasuhiro Honda, Keisuke Yamamoto, Kosuke Kadooka, Shun Nishino, Takeaki Kudo, Kenji Ogata, Nehiro Kuriyama, Mitsuru Ohishi, Yoshisato Shibata

https://doi.org/10.1253/circrep.CR-26-0053

Short- and Mid-Term Outcomes of Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation in Octogenarians

Yojiro Machii, Takashi Kakuta, Naonori Kawamoto, Kizuku Yamashita, Kota Suzuki, Ayumi Ikuta, Rieko Kutsuzawa, Yuki Tadokoro, Satsuki Fukushima

https://doi.org/10.1253/circrep.CR-25-0328

Research Letter

Practical Training of the Initial Response to Acute Myocardial Infarction Using a High-Performance Simulator Based on Kolb’s Experiential Learning Model

Tomonori Itoh, Tsubasa Matsumura, Masaru Gamasawa, Jun Aizawa

https://doi.org/10.1253/circrep.CR-26-0043

In-Hospital and Long-Term Clinical Outcomes in Patients With Acute Myocardial Infarction Categorized as SCAI Shock Stage B

Hisashi Sato, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Kei Yamamoto, Takunori Tsukui, Masashi Hatori, Taku Kasahara, Yusuke Watanabe, Shun Ishibashi, Masaru Seguchi, Hideo Fujita

https://doi.org/10.1253/circrep.CR-25-0270

Statement / Opinion

Task Shifting in Cardiac Ablations Compared With Percutaneous Coronary Interventions ― The Japanese Circulation Society Chugoku-Shikoku Regional Survey Subanalysis ―

Noriko Fukue, Takeshi Suetomi, Tomomi Matsuura, Mari Ishida, Makiko Taniyama, Natsuko Mukai-Yatagai, Takahiro Sakamoto, Tomoko Tamada, Shiro Uemura, Yukiko Nakano

https://doi.org/10.1253/circrep.CR-25-0329

Association of Weight Loss With Improvement in Metabolic Status Among People Eligible for the Specific Health Guidance Program

Masachika Nishikawa, Yuta Suzuki, Toshiyuki Ko, Hidehiro Kaneko, Akira Okada, Norifumi Takeda, Hiroyuki Morita, Katsuhito Fujiu, Tatsuhiko Azegami, Kaori Hayashi, Kaori Kitaoka, Katsuyuki Miura, Yuji Furui, Koichi Node, Hideo Yasunaga, Masaomi Nangaku, Norihiko Takeda

https://doi.org/10.1253/circrep.CR-25-0266

Research Letter

Three-Color SUVLV-Normalized SPECT/CT to Visualize Dynamic Pulmonary Perfusion in Chronic Thromboembolic Pulmonary Hypertension

Daiki Kishigami, Hiroto Shimokawahara, Kazunori Takahashi, Soichiro Kobashi, Hiromi Matsubara

https://doi.org/10.1253/circrep.CR-26-0041

Impact of Geographic Factors on Outpatient Cardiac Rehabilitation Adherence After Transcatheter Aortic Valve Implantation

Naonori Tashiro, Yusuke Matsumoto, Shouta Abe, Toshiki Kitajima, Yuya Yokota, Shinji Koba, Toshiro Shinke

https://doi.org/10.1253/circrep.CR-25-0290

Research Letter

Development of a Heart Failure Exacerbation Symptom Response System ― A Delphi Study ―

Motohiro Sano, Sho Okada, Yasuyuki Hirano, Tomoko Majima, Yoshio Kobayashi

https://doi.org/10.1253/circrep.CR-26-0021

Research Letter

Practical Septal Pacing for Atrioventricular Block ― A Simplified Septal Strategy With Stable Thresholds Compared With His Bundle Pacing ―

Shun Takeuchi, Rie Aoyama, Takashi Uchiyama, Tomohiko Hayashi, Shinichi Okino, Shigeru Fukuzawa

https://doi.org/10.1253/circrep.CR-26-0040

Protocol Paper

Inspiratory Muscle Training in Older Patients With Acute Heart Failure ― Design and Rationale of a Multi-Arm Parallel-Group Randomized Controlled Trial ―

Ren Takahashi, Junichi Yokota, Eiki Tsushima

https://doi.org/10.1253/circrep.CR-25-0313

Significance of Lipoprotein(a) in Coronary Artery Disease ― A Comparative Study of Patients Undergoing Percutaneous Coronary Intervention and Healthy Individuals ―

Tomoaki Okada, Kentaro Ejiri, Toru Miyoshi, Kosuke Seiyama, Jun Hasegawa, Masatomo Ozaki, Masahiro Sogo, Satoko Ugawa, Kazumasa Nosaka, Masayuki Doi

https://doi.org/10.1253/circrep.CR-26-0027

Prevalence and Prognostic Impact of Physical Dysfunction, Cachexia, and Dysphagia in Older Patients With Heart Failure

Koji Matsuo, Kazuhiro Mibu, Daiki Onoda, Kikka Kobayashi, Hiroaki Tatsuki, Seiji Tamiya

https://doi.org/10.1253/circrep.CR-26-0008

Estimated Plasma Volume and Heart Failure-Related Events in Hospitalized Patients With Stage A?D Heart Failure

Yoichiro Otaki, Tetsu Watanabe, Rin Kitagawa, Sakyo Urasawa, Daisuke Kinoshita, Masahiro Wanezaki, Shigehiko Kato, Harutoshi Tamura, Takanori Arimoto, Masafumi Watanabe

Prognostic Value of Right Ventricular Septal Longitudinal Strain in Intermediate-Risk Pulmonary Embolism

Ayumi Eguchi, Shunsuke Eguchi, Yoshiyuki Orihara, Michael Pfeiffer, Brandon Peterson, Mohammed Ruzieh, John Boehmer, John Gorcsan III, Ryan Wilson

Characterizing Manifestations of Optical Coherence Tomography in Pulmonary Arterial Lesions

Jielong Lin, Jiawei Long, Wenliang Guo, Xiaofeng Wu, Xinye Xia, Meiyan Chen, Dongda Zhou, Cheng Hong

Complete Low-Voltage Area Ablation in Persistent Atrial Fibrillation ― Post Hoc Subanalysis of the SUPPRESS-AF Trial ―

Yasuharu Matsunaga-Lee, Yasuyuki Egami, Masaru Abe, Hiroaki Nohara, Shodai Kawanami, Koji Yasumoto, Naotaka Okamoto, Masamichi Yano, Masami Nishino, Masaharu Masuda, Akihiro Sunaga, Nobuaki Tanaka, Tetsuya Watanabe, Hitoshi Minamiguchi, Takafumi Oka, Tomoko Minamisaka, Takashi Kanda, Masato Okada, Masato Kawasaki, Yasuhiro Matsuda, Koji Tanaka, Nobuhiko Makino, Hirota Kida, Shungo Hikoso, Tomoharu Dohi, Koichi Inoue, Yohei Sotomi, Yasushi Sakata

Interhospital Image Sharing for Cardiovascular Emergencies ― Results of a Nationwide Survey on Current Adoption―

Nobuyoshi Azuma, Hitoshi Yokoyama, Mitsuaki Isobe, Yasushi Sakata, Shigeki Kushimoto, Naoto Morimura, Takashi Hasegawa, Kenichi Tsujita, Yoshikatsu Saiki, Noboru Motomura, Yoshihiro Morino, Shungo Hikoso, Katsuki Okada, Hitoshi Ogino, Shinji Miyamoto, Hiroyuki Kamiya, Kazuhiro Sase, Hiroshi Ohtsu, Noriyasu Morikage, Kimihiro Komori, Yuichi Ueda

Pediatric Cardiology and Adult Congenital Heart Disease

Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) Reflects Global Pathophysiology and Predicts All-Cause Morbidity and Mortality in Patients With Fontan Circulation

Hideo Ohuchi, Aki Mori, Yoshihito Morimoto, Yoshiaki Kato, Kazuto Fujimoto, Toru Iwasa, Isao Shiraishi, Kenichi Kurosaki, Michikazu Nakai

Sinus Rhythm Maintenance After Pulsed-Field Ablation Is Associated With Improved Right Ventricular?Pulmonary Artery Coupling Without Significant Increase in Pulmonary Artery Pressure

Akio Chikata, Takeshi Kato, Shuhei Fujita, Kazuo Usuda, Michiro Maruyama, Kan-ichi Otowa, Takashi Kusayama, Kenshi Hayashi, Masayuki Takamura

Prediction of Atrial Fibrillation Using Artificial Intelligence-Enhanced Electrocardiography ― Does Left Atrial Size Matter? ―

Naomi Hirota, Shinya Suzuki, Jun Motogi, Tsuneo Takayanagi, Takuya Umemoto, Hiroshi Nakai, Takuto Arita, Naoharu Yagi, Mikio Kishi, Hiroto Kano, Shunsuke Matsuno, Yuko Kato, Takayuki Otsuka, Junji Yajima, Tokuhisa Uejima, Yuji Oikawa, Takeshi Yamashita

Prognostic Value of Mid-Range QRS Duration in Patients With Heart Failure With Reduced Ejection Fraction

Shota Saito, Taro Temma, Toshiyuki Nagai, Motoki Nakao, Isao Yokota, Atsushi Tada, Taro Koya, Suguru Ishizaka, Yoshifumi Mizuguchi, Fusako George, Yoshiya Kato, Yuki Takahashi, Shogo Imagawa, Ko Motoi, Yusuke Tokuda, Junichi Matsumoto, Masashige Takahashi, Hiroshi Okamoto,
Masaharu Machida, Takahiko Saito, Toshihiro Shimizu, Toshihisa Anzai, on behalf of the ELMSTAT-HF Investigators

Distinct Metabolomic and Clinical Phenotypes of Depression in Heart Failure ― Pilot Exploratory Analysis ―

Yoshiharu Kinugasa, Hiroko Kamitani-Noguchi, Kensuke Nakamura, Masayuki Hirai, Midori Manba, Natsuko Ishiga, Takeshi Sota, Natsuko Nakayama, Tomoki Ota, Masahiko Kato, Kazuhiro Yamamoto

Efficacy and Safety of Acoramidis in Japanese Adults With Symptomatic Transthyretin Amyloid Cardiomyopathy

Jin Endo, Kenichi Tsujita, Chisato Izumi, Toshiyuki Yano, Hiroaki Kitaoka, Yoshiki Sekijima, Nobuhiro Tahara, Shunsuke Ishii, Takahiro Okumura, Toru Hashimoto, Mitsuhiro Fukata, Tohru Minamino, Aileen Raizner, Yi Chen, Yasushi Otsuka, Michele F. Mercuri, Masatoshi Minamisawa, Yukio Ando

https://doi.org/10.1253/circrep.CR-26-0013

Impact of Radiation Therapy on Diastolic Function and Cardiac Troponin I Levels in Cancer Patients Undergoing Contemporary Radiotherapy

Fumika Haga, Masayoshi Oikawa, Tetsuya Tani, Tetsuro Yokokawa, Shunsuke Miura, Tomofumi Misaka, Takashi Kaneshiro, Akiomi Yoshihisa, Takafumi Ishida, Yasuchika Takeishi

https://doi.org/10.1253/circrep.CR-26-0026

Research Letter

Incidence of Hypotension and Clinical Characteristics After the Introduction of Angiotensin Receptor-Neprilysin Inhibitors in Patients With Acute Decompensated Heart Failure ― Effects on Cardiac Rehabilitation ―

Kaori Ando, Kengo Obata, Soichiro Fuke, Ryota Matsuzawa, Akira Tamaki

https://doi.org/10.1253/circrep.CR-26-0016

Efficacy of Acoramidis in Adults With Transthyretin Amyloid Cardiomyopathy ― Propensity Score Comparison Between a Single-Arm Open-Label Phase 3 Trial in Japan and a Global Double-Blind Phase 3 Trial ―

Nobuhiro Tahara, Aileen Raizner, Yi Chen, Michele F. Mercuri, Masatoshi Minamisawa, on behalf of the Phase 3 Japan Study Investigators

https://doi.org/10.1253/circrep.CR-25-0304

Research Letter

Tooth Count and Prognosis in Older Patients With Heart Failure

Koji Matsuo, Kikka Kobayashi, Daiki Onoda, Kazuhiro Mibu, Seiji Tamiya

https://doi.org/10.1253/circrep.CR-26-0025

Daily Digital Device Use and eHealth Literacy Among Hospitalized Older Adults With Heart Failure ― A Multicenter Cohort Study ―

Shingo Koyama, Iwao Kojima, Yuki Kimura, Hiroaki Asada, Jinshiro Saito, Ryota Yokoyama, Takuma Kawashima, Satoru Yoshioka, Toshiaki Sakakibara, Keisuke Takada, Yosuke Sugita, Misa Miura, Satoshi Sakai

https://doi.org/10.1253/circrep.CR-25-0330

Acute Decompensated Heart Failure Complicated by Ischemic Stroke and Its Association With Hemoglobin Levels

Yusuke Yamazaki, Yasuyuki Shiraishi, Shun Kohsaka, Shogo Ikegami, Takashi Kohno, Yuji Nagatomo, Mitsunobu Kitamura, Munehisa Sakamoto, Michiru Nomoto, Toshiyuki Takahashi, Masatake Kobayashi, Satoshi Higuchi, Masaki Ieda, Tsutomu Yoshikawa, for the West Tokyo Heart Failure Registry Investigators

https://doi.org/10.1253/circrep.CR-26-0015

Impact of Low Vision on Wound Healing in Patients With Chronic Limb-Threatening Ischemia

Eiji Karashima, Keiichiro Kishikawa, Shioto Yasuda, Takeo Kaneko

https://doi.org/10.1253/circrep.CR-25-0327

Relationship of Depression With Incident Cardiovascular Disease in Individuals With Chronic Kidney Disease

Daiki Kuroyanagi, Hidehiro Kaneko, Yuta Suzuki, Akira Okada, Hiroyuki Morita, Norifumi Takeda, Katsuhito Fujiu, Kaoruko Komuro, Toshiyuki Ko, Ryunosuke Mitsuno, Takashin Nakayama, Tatsuhiko Azegami, Kaori Hayashi, Hideo Yasunaga, Norihiko Takeda, Akio Kawamura

https://doi.org/10.1253/circrep.CR-25-0262

Recurrence of Takotsubo Syndrome ― Incidence and Clinical Characteristics ―

Yuki Nishimura, Junya Komatsu, Hiroki Nakayama, Hiroki Sugane, Hayato Hosoda, Ryu-ichiro Imai, Yoko Nakaoka, Koji Nishida, Shinji Mito, Shu-ichi Seki, Toru Kubo, Naohito Yamasaki, Hiroaki Kitaoka, Sho-ichi Kubokawa, Kazuya Kawai, Naohisa Hamashige, Yoshinori Doi

https://doi.org/10.1253/circrep.CR-25-0211

Association Between Severe Aortic Stenosis and Amyloid Deposition in the Myocardium of Patients With Wild-Type Transthyretin Cardiac Amyloidosis

Kentaro Furukawa, Hiroaki Kawano, Ryohei Akashi, Chisa Eguchi, Tomohiro Honda, Tadatomo Fukushima, Yusuke Takenaka, Masamichi Eguchi, Tsuyoshi Yoshimuta, Takashi Kudo, Masahiro Nakashima, Mitsuharu Ueda, Satoshi Ikeda, Koji Maemura

https://doi.org/10.1253/circrep.CR-26-0014

Machine Learning Models Incorporating Nursing Care Needs to Predict 180-Day Prognosis in Patients With Heart Failure ― Validation With Discrimination and Calibration Analyses ―

Takuya Nishino, Katsuhito Kato, Shuhei Tara, Daisuke Hayashi, Tomohisa Seki, Toru Takiguchi, Yoshiaki Kubota, Takeshi Yamamoto, Mitsunori Maruyama, Eitaro Kodani, Nobuaki Kobayashi, Akihiro Shirakabe, Toshiaki Otsuka, Shoji Yokobori, Yukihiro Kondo, Kuniya Asai

https://doi.org/10.1253/circrep.CR-25-0337

Effect of Comprehensive Outpatient Cardiac Rehabilitation on All-Cause Mortality After Transcatheter Aortic Valve Implantation

Daichi Kobayashi, Masakazu Saitoh, Kentaro Hori, Shinya Tajima, Kotaro Takizawa, Junko Sakamoto, Atsuko Nakayama

https://doi.org/10.1253/circrep.CR-25-0341

Research Letter

Exploratory Evaluation of Multidisciplinary Collaboration in Developing a Community-Based Heart Failure Care System

Yuka Odate, Yuki Nakano, Mayumi Nagasaka, Yukiko Hirose, Misao Suzuki, Saori Fujii, Kumiko Toshinskiy, Naomi Yaguchi, Tsuyoshi Ono

https://doi.org/10.1253/circrep.CR-26-0012

Association Between Locomotive Syndrome and N-Terminal Pro B-Type Natriuretic Peptide Concentration in a Health Screening Cohort ― A Retrospective Cross-Sectional Study ―

Chiaki Mizuno, Hiroaki Hiraiwa, Shinya Yokoyama, Takanori Ito, Kazuki Sahara, Takashi Honda,
Taku Tanaka, Tetsuhito Kojima, Naoyoshi Kariya, Ryota Ito, Shingo Kazama, Toru Kondo, Ryota Morimoto, Hiroki Kawashima, Toyoaki Murohara

https://doi.org/10.1253/circrep.CR-25-0323

Relationship Between Post-Procedural Angiography-Derived Index of Microcirculatory Resistance and Periprocedural Myocardial Injury After Percutaneous Coronary Intervention

Tetsuya Matsuyama, Takayuki Okamura, Tatsuhiro Fujimura, Yosuke Miyazaki, Takeshi Suetomi, Hideaki Akase, Yuki Nakata, Keita Kaneyuki, Motoaki Sano

https://doi.org/10.1253/circrep.CR-26-0006

Refining the Cardiovascular?Kidney?Metabolic Staging System for Improved Risk Stratification of Chronic Kidney Disease Progression in Type 2 Diabetes

Tomohito Gohda, Nozomu Kamei, Marenao Tanaka, Masato Furuhashi, Tatsuya Sato, Mitsunobu Kubota, Michiyoshi Sanuki, Yasuhiko Tomino, Yusuke Suzuki, Maki Murakoshi

https://doi.org/10.1253/circrep.CR-25-0345

Impaired Atrial Natriuretic Peptide Secretion as a Marker of Advanced Atrial Fibrillation

Satoshi Oka, Koji Miyamoto, Chisa Asahina, Toshihiro Nakamura, Akinori Wakamiya, Nobuhiko Ueda, Kenzaburo Nakajima, Tsukasa Kamakura, Mitsuru Wada, Kohei Ishibashi, Yuko Inoue, Takeshi Aiba, Kengo Kusano

https://doi.org/10.1253/circrep.CR-25-0340

Association Between Outpatient Cardiac Rehabilitation and Falls in Older Patients With Cardiovascular Disease ― A 1-Year Longitudinal Study ―

Kohei Shiota, Masakazu Saitoh, Kotaro Iwatsu, Tomoyuki Morisawa, Tetsuya Takahashi, Junya Nishimura, Masamichi Mochizuki, Eriko Kitahara, Toshiyuki Fujiwara, Miho Yokoyama, Tohru Minamino

https://doi.org/10.1253/circrep.CR-25-0267

Research Letter

Clinical Factors Associated With Positive 99 mTc-Pyrophosphate Scintigraphy Beyond Kumamoto Criteria in a Real-World Cohort

Rie Aoyama, Tatsuki Ugawa, Shinichi Okino, Shigeru Fukuzawa

https://doi.org/10.1253/circrep.CR-26-0005

Evaluation of Exercise Tolerance in Cancer Patients With Cardiovascular Complications ― A Japanese Single-Center Retrospective Study Using Cardiopulmonary Exercise Testing ―

Asaki Saijo, Hidetaka Itoh, Yuko Tanabe, Chinatsu Komiyama, Ayako Harima, Tetsuo Yamaguchi, Yasuhiro Tomita, Yuji Miura, Takahide Kodama

https://doi.org/10.1253/circrep.CR-25-0331

Clinical Impact of the ‘Delta-Aortic Valve Gradient’, the Reduction in the Mean Aortic Valve Pressure Gradient After Transcatheter Aortic Valve Implantation, on Left Ventricular Ejection Fraction Improvement and Long-Term Mortality in Patients With Severe Aortic Stenosis and Left Ventricular Dysfunction

Naoto Murakami, Kenichi Ishizu, Masaomi Hayashi, Shinichi Shirai

https://doi.org/10.1253/circrep.CR-25-0227

Effect of Mitochondrial Ca2+ Uptake on Arrhythmogenesis in Right Ventricular Hypertrophy in Rats and Mice

Haruka Sato, Kazunori Kumasaka, Yuka Someya, Yui Takahashi, Shiori Akazawa, Kao Takeda, Sana Koyama, Tsuyoshi Okumura, Masahito Miura

Targeting Nuclear Factor-κB1 With Andrographolide ― Novel Strategy to Inhibit Vascular Lesions and Aneurysm Formation in Abdominal Aortic Aneurysm ―

Ying Wen, Xing Fu, Zheng Chen, Jianxiang Wang, Yingying Liu, Yixian Ren, Zefeng Lin, Luhao Liu, Wai Ho Tang

Small Dense Low-Density Lipoprotein Cholesterol Predicts Long-Term Coronary Artery Disease Recurrence in Patients Without Metabolic Dyslipidemia

Shinji Koba, Yuya Yokota, Noriyuki Satoh, Yasuki Ito, Fumiyoshi Tsunoda, Koshiro Sakai, Yuya Nakamura, Makoto Shoji, Tsutomu Hirano, Toshiro Shinke

Bisoprolol vs. Carvedilol After Percutaneous Coronary Intervention in Acute Myocardial Infarction With Reduced Left Ventricular Ejection Fraction

Jun-Chang Jeong, Jong-Il Park, Kang-Un Choi, Jong-Ho Nam, Chan-Hee Lee, Jang-Won Son, Jong-Seon Park, Jang-Hoon Lee, Seung-Ho Hur, Kyeong-Ho Yun, Hyo-Soo Kim, Ju-Han Kim, Youngkeun Ahn, Myung-Ho Jeong, Ung Kim, on behalf of the KAMIR-V Registry Investigators

Optimizing Single-Lead Electrocardiogram Orientation Improves Detection of Left Ventricular Dysfunction

Hisaki Makimoto, Takayuki Okatani, Masafumi Sato, Shinnosuke Sawano, Satoshi Kodera, Kenji Harada, Kazunori Anno, Tomoyuki Kabutoya, Masashi Kamioka, Tomonori Watanabe, Hiroaki Watanabe, Takahiro Komori, Ayako Yokota, Yasushi Imai, Yukiyo Ogata, Takahide Kohro, Norihiko Takeda, Tetsuya Matoba, Ryozo Nagai, Kazuomi Kario

Research Letter

Association of Lipid Core Burden Index With Early Progression of Cardiac Allograft Vasculopathy in Patients After Heart Transplantation

Kenta Otsuka, Sakae Takenaka, Toshiyuki Nagai, Takuma Sato, Takao Konishi, Atsushi Tada, Takeshi Hamaya, Yuki Mori, Akinori Takahashi, Sou Sasaki, Kento Tamano, Toshifumi Tamura, Sho Kazui, Yutaro Yasui, Yuta Kobayashi, Taro Temma, Kiwamu Kamiya, Satoru Wakasa, Toshihisa Anzai

E2F5 Promotes Vascular Endothelial Cell Proliferation and Angiogenesis in Diabetic Lower Limb Ischemia via an Autophagy-Related Mechanism

Yuyan Zhan, Hongwei Shi, Xiaoying Miu, Xiaoping Peng, Jungang Nie, Dong Liu, Qiong Duan, Ting Kang

Research Letter

Association Between Ventricular?Arterial Coupling and C-Reactive Protein in Patients at Risk for Heart Failure

Yasuyoshi Takei, Hirofumi Tomiyama, Akira Yamashina, Yukihito Higashi, Kazuhiro Satomi

Research Letter

Prevalence and Clinical Characteristics of Patients With Heart Failure With Preserved Ejection Fraction Who Meet the Obesity-Related Eligibility Criteria for Subcutaneous Incretin Receptor Agonists in Japan ― Insights From the PARACLETE Study ―

Ken Nishikawa, Sho Suzuki, Masatoshi Minamisawa, Akane Yamakawa, Shinya Hiramitsu, Katsuya Onishi, Dai Yumino, Kenji Shiino, Tomoya Ueda, Atsuhiko Kawamoto, Masato Kasahara, Shungo Hikoso, Koichiro Kuwahara, Yoshihiko Saito

Contribution of Non-Sustained Ventricular Tachycardia to the Primary Prevention of Sudden Cardiac Death ― Validation of Current Japanese Circulation Society / Japanese Heart Rhythm Society Guideline Recommendations in the Nippon Storm Study ―

Ryobun Yasuoka, Masahiro Maruyama, Takashi Noda, Gaku Nakazawa, Takashi Nitta, Yoshifusa Aizawa, Tohru Ohe, Takashi Kurita, Nippon Storm Investigators

Research Letter

Time-Dependent Analysis of Blood Sampling to Detect Metabolic Ischemia ― Serial Coronary Artery?Coronary Sinus Lactate Analysis During Acetylcholine Provocation ―

Tsuyoshi Ito, Masashi Yokoi, Shuichi Kitada, Yu Kawada, Tatsuya Mizoguchi, Sayuri Yamabe, Atsushi Niwa, Toshihiko Goto, Yoshihiro Seo

Prognostic Impact of Quantitative Flow Ratio-Derived Physiology for Intermediate Non-Infarct-Related Artery in Acute Myocardial Infarction

Sho Nakao, Takayuki Ishihara, Takuya Tsujimura, Yosuke Hata, Masaya Kusuda, Wataru Ariyasu, Subaru Fujii, Toshiaki Mano

Vascular Biology and Vascular Medicine

Review Article

Association Between Chronic Inflammation and Cardiovascular Disease ― Focus on High-Sensitivity C-Reactive Protein ―

Tomoya Hara, Masataka Sata

Two Faces of Cardiovascular Actions of Testosterone Dependent on the Presence or Absence of Nitric Oxide Synthases in Mice

Shotaro Higa, Mayuko Sakanashi, Masato Tsutsui, Takashi Tasaki, Akihide Tanimoto, Yuji Taira, Hiroaki Shimokawa, Yukio Kuniyoshi, Kojiro Furukawa

Prognostic Value of the Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio for Cardiovascular Events in Statin-Treated Type 2 Diabetes With Diabetic Retinopathy Without Prior Cardiovascular Disease

Hiroka Nakashima, Shota Ikeda, Keisuke Shinohara, Sho Matsumoto, Daisuke Yoshida, Ryosuke Nakashima, Yoshiyasu Ono, Ryohei Miyamoto, Ayano Hara, Shouji Matsushima, Toru Hashimoto, Takeo Fujino, Kayo Misumi, Shunsuke Katsuki, Keimei Yoshida, Junji Kishimoto, Hiroshi Itoh, Issei Komuro, Hiroyuki Tsutsui, Kohtaro Abe

High Human Epididymis Protein 4 Levels Are Associated With Lower Systolic Function and Poor Prognosis in Heart Failure With Reduced Ejection Fraction

Yuki Okuno, Shinsuke Hanatani, Fumihiko Ogata, Shinpei Yamaguchi, Masahiro Yamamoto, Naoto Kuyama, Masanobu Ishii, Hiroki Usuku, Eiichiro Yamamoto, Seitaro Oda, Yasuhiro Izumiya, Hirofumi Soejima, Hiroaki Kawano, Toshinori Hirai, Kenichi Tsujita

Height- and Body Mass Index-Based Sarcopenia ― Prognostic and Functional Implications in Older Patients Hospitalized for Heart Failure ―

Yuta Ozaki, Yusuke Uemura, Shigefumi Honda, Toru Kondo, Shingo Kazama, Kenji Takemoto, Masato Watarai, Toyoaki Murohara

Tenascin-C and Fibrosis as Prognostic Predictors of　Peripartum Cardiomyopathy　― A Histopathological Study ―

Kisaki Amemiya, Junko Nakashima, Keiko Ohta-Ogo, Hatsue Ishibashi-Ueda, Manabu Matsumoto, Yoshihiko Ikeda, Yoshiaki Morita, Yasumasa Tsukamoto, Jun Yoshimatsu, Kinta Hatakeyama, Chizuko Aoki-Kamiya

Changes in Natriuretic Peptide Levels and Cardiac Structure in Patients Treated With Vericiguat ― VERIFY-HF Registry ―

Kenji Kanenawa, Kenji Ando, Takahito Nasu, Wataru Fujimoto, Nobuyuki Kagiyama, Yasuyuki Shiraishi, Shunsuke Ishii, Takeshi Ijichi, Gaku Nakazawa, Koshiro Kanaoka, Shingo Matsumoto, VERIFY-HF Investigators

Cathelicidin Links Visceral Fat Accumulation and Coronary Artery Disease

Motoki Taniguchi, Akira Taruya, Chie Kitahara, Shingo Ota, Takashi Kato, Yuki Desaki, Izumi Sasaki, Yosuke Katayama, Teruaki Wada, Masahiro Takahata, Keisuke Satogami, Yuichi Ozaki, Manabu Kashiwagi, Yasutsugu Shiono, Kentaro Honda, Takashi Yamano, Kazushi Takemoto, Akio Kuroi, Hironori Kitabata, Hiroaki Hemmi, Takaaki Matsuoka, Yoshiharu Nishimura, Atsushi Tanaka

Vascular Biology and Vascular Medicine

Diagnostic Ability of the Japanese Version of the High Bleeding Risk Criteria in Patients With Lower Extremity Peripheral Arterial Disease

Tadahiro Matsumoto, Yuichi Saito, Yuji Ohno, Kayo Yamamoto, Norikiyo Oka, Masayuki Takahara, Sakuramaru Suzuki, Raita Uchiyama, Masahiro Suzuki, Yo Iwata, Satoru Kobayashi, Yoshio Kobayashi

Assessment of and Factors Contributing to Adequate Endothelization After Drug-Eluting Stent Implantation

Masami Nishino, Yasuyuki Egami, Hiroaki Nohara, Shodai Kawanami, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano, Tatsuya Shiraki, Daisuke Nakamura, Isamu Mizote, Takayuki Ishihara, Toshiaki Mano, Takahisa Yamada, Naoki Itaya, Takaharu Nakayoshi, Takafumi Ueno, Daisaku Nakatani, Shungo Hikoso, Shinsuke Nanto, Yasushi Sakata

A Phase 2, Randomized, Clinical Trial of Inhaled Nitric Oxide for Acute Severe Right Heart Failure With Pulmonary Hypertension (PHiNO Study)

Takeshi Ogo, Jin Ueda, Akihiro Tsuji, Ryotaro Asano, Hiroya Hayashi, Ryo Takano, Shinya Fujisaki, Koko Asakura, Haruko Yamamoto

Impact of Genetic Testing Among Patients With Familial Hypercholesterolemia on Adverse Cardiovascular Events ― The Hokuriku-Plus Familial Hypercholesterolemia Registry Study ―

Hayato Tada, Yasuaki Takeji, Chiaki Goten, Hirofumi Okada, Shohei Yoshida, Masaya Shimojima, Akihiro Nomura, Mika Mori, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Noboru Fujino, Katsuhiko Nagase,Masa-aki Kawashiri, Masayuki Takamura, on behalf of the Hokuriku-plus Familial Hypercholesterolemia Registry Study Group

Apple Watch-Guided Anticoagulation After Atrial Fibrillation Ablation ― The Up to AF Trial ―

Akihiro Sunaga, Nobuaki Tanaka, Yasuyuki Egami, Hitoshi Minamiguchi, Masato Kawasaki, Takafumi Oka, Koichi Inoue, Masaharu Masuda, Miwa Miyoshi, Nobuhiko Makino, Yuko Hirao, Masamichi Yano, Takashi Kanda, Tetsuya Watanabe, Takayuki Sekihara, Tatsuhisa Ozaki, Daisaku Nakatani, Katsuki Okada, Hirota Kida, Yuki Matsuoka, Daisuke Sakamoto, Tomomi Yamada, Yohei Sotomi, Yasushi Sakata, on behalf of the OCVC-Arrhythmia Investigators

Review Article

Cardiovascular, Kidney, and Metabolic Network Medicine ― Past, Present, and Future Challenges and Directions ―

JCS 2026 Guideline on the Management of Infective Endocarditis

Chisato Izumi, Masao Daimon, Shuichiro Kaji, Akiko Masumoto, Kyomi Ashihara, Masashi Amano, Shiro Uemura, Hideki Ota, Takahiro Ohara, Kenji Okada, Takayuki Kawamura, Masahiko Goya, Masatoshi Koga, Jiro Sakamoto, Tetsu Sakamoto, Hiroshi Sasano, Masayuki Shiozawa, Taro Shimizu, Jun Takahashi, Kazuhiko Nakano, Ryota Nomura, Kazuki Hisatomi, Kenji Fukushima, Soichiro Henmi, Takashi Miura, Kotaro Mitsutake, Tomoyuki Miyamoto, Tomoaki Murakami, Hirotsugu Yamada, Ken-ichi Yanagida, Go Yamamoto, Daisuke Yoshioka, Yutaka Otsuji, Hiroaki Kitaoka, Toshimi Kimura, Akira Shiose, Satoshi Nakatani, on behalf of the Japanese Circulation Society Joint Working Group

JCS 2026 Guideline on Management of Large Vessel Vasculitis

Yoshikazu Nakaoka, Yoshiko Watanabe, Takahiko Sugihara, Kenji Nagasaka, Naoto Tamura, Hajime Yoshifuji, Nobuyuki Yajima, Fumika Aono, Takuya Hashimoto, Akihiro Ishizu, Tomohiro Iida, Tomonori Ishii, Takatoyo Kiko, Yasuhiro Maejima, Takako Miyamae, Yu Nakano, Toshihiro Nanki, Hiroaki Niiro, Hideki Ota, Noriko Okochi, Ken-ei Sada, Kunihiro Shigematsu, Haruhito A. Uchida, Yoshiyuki Abe, Chizuko Aoki-Kamiya, Yoh Arita, Takaya Handa, Ryosuke Hiwa, Manabu Honda, Ryuhei Ishihara, Jun Ishizaki, Shuichi Ito, Toru Iwahashi, Naomi Iwata, Keiichiro Kadoba, Yuji Kamiyama, Mai Kawazoe, Takashi Kida, Genki Kidoguchi, Daisuke Kobayashi, Kazuhiro Kobayashi, Atsushi Kurata, ... on behalf of the Japanese Circulation Society Joint Working Group

Research Letter

Baseline Prolonged QRS Duration May Predict In-Hospital Outcomes of Patients With Acute Myocarditis ― Multicenter Observational Study ―

Ayano Yoshida, Takuma Takada, Eiji Shibahashi, Takuro Abe, Kensuke Shimazaki, Takanori Kawamoto, Motoko Kametani, Natsuko Satomi, Kazuho Kamishima, Takashi Saito, Erina Tomari, Atsushi Honda, Atsushi Takagi, Kyomi Ashihara, Junichi Yamaguchi, Kentaro Jujo

https://doi.org/10.1253/circrep.CR-25-0306

Clinical Impact of Drug-Coated Balloon-Based Percutaneous Coronary Intervention in Coronary Artery Disease Patients With Chronic Heart Failure

Tetsuya Takahashi, Taiga Ishigaki, Wataru Katawaki, Taku Toshima, Yu Kumagai, Tamon Yamanaka, Masafumi Watanabe

https://doi.org/10.1253/circrep.CR-25-0320

Short-Term Outcomes of Intra-Aortic Balloon Pump vs. Microaxial Flow Pump for Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation

Saeko Iikura, Yuki Ikeda, Shohei Nakahara, Yuki Watanabe, Yosuke Haruki, Yu Takigami, Yuko Eda, Yuichiro Iida, Takeru Nabeta, Shunsuke Ishii, Junya Ako

https://doi.org/10.1253/circrep.CR-25-0283

Research Letter

Comparison of Landiolol and Verapamil for Postoperative Atrial Fibrillation ― A Prospective Randomized Study ―

Naoto Yabu, Tomoyuki Minami, Shota Yasuda, Yoshiyuki Kobayashi, Aya Saito

https://doi.org/10.1253/circrep.CR-25-0335

Preoperative Sarcopenia and Postoperative Activities of Daily Living Decline in Patients Undergoing Elective Cardiovascular Surgery

Tomohiro Kato, Yuta Ozaki, Shigefumi Honda, Yusuke Uemura, Kenji Takemoto, Masato Watarai, Toyoaki Murohara

https://doi.org/10.1253/circrep.CR-25-0299

Long-Term Efficacy of Drug-Coated Balloon Angioplasty vs. Drug-Eluting Stent for De Novo Large-Vessel Coronary Arteries

Mayuka Masuda, Hiroyuki Yamamoto, Shinsuke Nakano, Nobuyuki Takahashi, Taishi Miyata, Tomohiro Inoue, Tomofumi Takaya

https://doi.org/10.1253/circrep.CR-25-0322

Admission Renal Dysfunction Severity as a Prognostic Factor in Older Patients With Acute Heart Failure

Kazuya Kito, Masakazu Saitoh, Yuji Mori, Keita Fujiyama, Masahiro Toda, Kotaro Iwatsu, Tomoyuki Morisawa, Tetsuya Takahashi, Michitaka Kato

https://doi.org/10.1253/circrep.CR-25-0274

Review Article

Pulsed Field Ablation for Atrial Fibrillation in Japan ― Current Status and Future Perspectives ―

https://doi.org/10.1253/circrep.CR-25-0284

Left vs. Normal QRS Axis During Left Bundle Branch Block Induced by Transcatheter Aortic Valve Replacement ― 3-Year Outcomes ―

Kenichi Sasaki, Shingo Kuwata, Masaki Izumo, Yukio Sato, Takahiko Kai, Taishi Okuno, Tetsu Tanaka, Masahiro Sekiguchi, Yoshihiro J. Akashi

https://doi.org/10.1253/circrep.CR-25-0249

Impact of Plaque Morphology on Drug-Coated Balloon Treatment Outcomes for Coronary Calcified Lesions ― An Optical Coherence Tomography Analysis ―

Masahiro Koide, Kan Zen, Tomotsugu Seki, Kento Fukui, Kazuaki Takamatsu, Jun Shiraishi, Satoaki Matoba

https://doi.org/10.1253/circrep.CR-25-0219

Research Letter

Association Between Symptom Characteristics, Knowledge Sources, and Patient Interpretation of Acute Coronary Syndrome ― Insights From the Japanese Circulation Society Chest Pain Registry ―

Masato Uchida, Satoshi Yoshimura, Kanna Arimoto, Hirotoshi Nishikita, Yohei Fushimura, Hirokazu Yokoi, Takuya Taniguchi, Chika Nishiyama, Yasunori Ueda, Taku Iwami, on behalf of the Education and Implementation for Cardiac Emergency Committee of the Japanese Circulation Society

https://doi.org/10.1253/circrep.CR-25-0301

Research Letter

From Working to Retirement-Age ― How Sleep Duration Is Related to Atrial Fibrillation Using 1-Week Holter-Electrocardiogram With Accelerometry ―

Tadashi Hoshiyama, Kenichi Tsujita, Yuko Inoue, Masanobu Ishii, Koichiro Kumagai, Takahisa Noma, Kenzaburo Nakajima, Yoshihiro Kokubo, Masatoshi Koga, Naoki Mochizuki, Hisao Ogawa, Kengo Kusano

https://doi.org/10.1253/circrep.CR-25-0310

Association of Geographical Distance and Residential Population Density With Clinical Outcomes in Acute Decompensated Heart Failure ― Insights From the Kyoto Congestive Heart Failure (KCHF) Registry ―

Erika Yamamoto, Takao Kato, Takeshi Morimoto, Hidenori Yaku, Yasutaka Inuzuka, Yodo Tamaki, Neiko Ozasa, Yusuke Yoshikawa, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Kazuya Nagao, Ryusuke Nishikawa, Kazushige Kadota, Yutaka Furukawa, Kenji Ando, Yukihito Sato, Koichiro Kuwahara, Takeshi Kimura, Koh Ono, on behalf of the KCHF Study Investigators

https://doi.org/10.1253/circrep.CR-25-0316

Protocol Paper

Development and Internal Validation of Machine-Learning Models for Short-Term Prediction of Day-to-Day Home Blood Pressure Variability Using IoT-Based Environmental and Activity Data ― Protocol for the AURA-BPV Study ―

Yoko M. Nakao, Atsushi Takayama, Koji Kawakami

https://doi.org/10.1253/circrep.CR-25-0314

Sex-Based Differences in the Effect of Short Dual Antiplatelet Therapy Followed by Prasugrel Monotherapy in High-Bleeding-Risk Patients After Percutaneous Coronary Intervention

Norihiro Kogame, Yoshihisa Nakagawa, Ken Kozuma, Raisuke Iijima, Anna Tsutsui, Yoshitaka Murakami, Masayuki Fukuzawa, Satoru Abe, Go Kato, Masato Nakamura

https://doi.org/10.1253/circrep.CR-25-0298

Initial Outcomes After Trans-Right Subclavian Transcatheter Aortic Valve Implantation ― Analysis of Device Coaxiality ―

Ryusuke Hamada, Kyohei Onishi, Masakazu Yasuda, Kosuke Fujita, Naoko Soejima, Tatsuya Miyoshi, Koichiro Matsumura, Shinsuke Kotani, Atsunori Okamura, Yoshitaka Iwanaga, Genichi Sakaguchi, Gaku Nakazawa

https://doi.org/10.1253/circrep.CR-25-0243