Supplement 1a.xlsx

	A	B	C	D	E	F	G	H	I	J	K	L	M	N	O
1	PeakID	Direction	Gene	Transcript	Gene chromosome	Gene transcription start	Gene transcription end	Gene strand	Peak chromsome	Peak start	Peak end	Peak mid to TSS	Promoter classification	Peak differential methylation	Differential methylation p-value
2	540	Hypermethylated in glucose-treated	AXDND1\|AXDND1	NR_073544\|NM_144696	chr1\|chr1	179365971\|179365719	179554735\|179554735	+\|+	chr1	179365858	179366329	123\|375	HCP\|HCP	0.294	0.002
3	821	Hypermethylated in glucose-treated	ZHX2	NM_014943	chr8	122781661	122974515	+	chr8	122780376	122780630	-1158	HCP	0.288	0.001
4	766	Hypermethylated in glucose-treated	TTC1	NM_003314	chr5	160009099	160065545	+	chr5	160008970	160009463	117	ICP	0.283	0.001
5	817	Hypermethylated in glucose-treated	CTHRC1\|CTHRC1	NM_001256099\|NM_138455	chr8\|chr8	103372432\|103371514	103383004\|103383004	+\|+	chr8	103371195	103372431	-619\|299	ICP\|HCP	0.277	0.000
6	558	Hypermethylated in glucose-treated	DDX21\|DDX21	NM_004728\|NM_001256910	chr10\|chr10	68956122\|68956439	68985069\|68985069	+\|+	chr10	68955595	68955842	-404\|-721	ICP\|HCP	0.259	0.002
7	737	Hypermethylated in glucose-treated	HTN1	NM_002159	chr4	70050414	70058848	+	chr4	70049305	70049572	-976	ICP	0.255	0.001
8	589	Hypermethylated in glucose-treated	LLPH-AS1	NR_125724	chr12	66130750	66134449	+	chr12	66130546	66131002	24	HCP	0.251	0.006
9	592	Hypermethylated in glucose-treated	TXNRD1	NM_003330	chr12	104286681	104350307	+	chr12	104286888	104287142	334	LCP	0.248	0.002
10	577	Hypermethylated in glucose-treated	LOC100507283	NR_103862	chr11	124800427	124834487	+	chr11	124799142	124799607	-1053	HCP	0.239	0.001
11	772	Hypermethylated in glucose-treated	RUFY1	NM_025158	chr5	179550560	179610026	+	chr5	179549914	179550939	-134	HCP	0.231	0.001
12	811	Hypermethylated in glucose-treated	CLN8	NM_018941	chr8	1763703	1786570	+	chr8	1762410	1763134	-931	HCP	0.221	0.001
13	750	Hypermethylated in glucose-treated	SAP30	NM_003864	chr4	173370941	173377532	+	chr4	173369716	173370186	-990	HCP	0.213	0.001
14	515	Hypermethylated in glucose-treated	ZMYM4	NM_005095	chr1	35268966	35421944	+	chr1	35267891	35268569	-736	HCP	0.207	0.002
15	620	Hypermethylated in glucose-treated	AQP9	NM_020980	chr15	58138195	58185908	+	chr15	58137761	58138203	-213	LCP	0.207	0.003
16	562	Hypermethylated in glucose-treated	OR51B4	NM_033179	chr11	5301013	5301946	-	chr11	5302706	5303183	-1931	LCP	0.206	0.002
17	672	Hypermethylated in glucose-treated	TANK	NM_001199135	chr2	161160427	161236172	+	chr2	161159921	161160806	-63	HCP	0.206	0.003
18	586	Hypermethylated in glucose-treated	H3F3C	NM_001013699	chr12	31791184	31792241	-	chr12	31791742	31792208	-791	HCP	0.206	0.004
19	684	Hypermethylated in glucose-treated	MRPL44	NM_022915	chr2	223957403	223967714	+	chr2	223956623	223957874	-155	HCP	0.205	0.002
20	646	Hypermethylated in glucose-treated	DLGAP1-AS1	NR_024101	chr18	3594113	3597379	+	chr18	3592950	3593208	-1034	LCP	0.205	0.005
21	790	Hypermethylated in glucose-treated	ZC2HC1B	NM_001013623	chr6	143864435	143938346	+	chr6	143864101	143864875	53	LCP	0.204	0.001
22	671	Hypermethylated in glucose-treated	HNMT	NM_006895	chr2	137964237	138016364	+	chr2	137964291	137964553	185	LCP	0.203	0.004
23	752	Hypermethylated in glucose-treated	FAM149A	NM_001006655	chr4	186149172	186172663	+	chr4	186148424	186149234	-343	LCP	0.201	0.008
24	841	Hypermethylated in glucose-treated	BMX	NM_203281	chrX	15500776	15556529	+	chrX	15500287	15501184	-40	ICP	0.199	0.001
25	662	Hypermethylated in glucose-treated	PQLC3	NM_001282710	chr2	11155371	11178872	+	chr2	11154860	11155204	-339	HCP	0.194	0.004
26	778	Hypermethylated in glucose-treated	HIST1H3I	NM_003533	chr6	27871844	27872321	-	chr6	27871860	27872625	-398	ICP	0.193	0.001
27	685	Hypermethylated in glucose-treated	NYAP2	NM_020864	chr2	225400885	225654018	+	chr2	225399592	225400058	-1060	LCP	0.192	0.003
28	552	Hypermethylated in glucose-treated	OR2L1P	NR_002145	chr1	247990266	247991191	+	chr1	247989016	247989284	-1116	LCP	0.191	0.004
29	596	Hypermethylated in glucose-treated	FGF9	NM_002010	chr13	21671075	21704501	+	chr13	21671006	21671472	164	HCP	0.190	0.002
30	863	Hypermethylated in glucose-treated	PRY\|PRY2	NM_004676\|NM_001002758	chrY\|chrY	22490396\|22490396	22514637\|22514637	+\|+	chrY	22489148	22489822	-911\|-911	LCP\|LCP	0.189	0.000
31	612	Hypermethylated in glucose-treated	ZNF410	NM_001242927	chr14	73886614	73932288	+	chr14	73886257	73886927	-22	HCP	0.189	0.002
32	736	Hypermethylated in glucose-treated	SLAIN2	NM_020846	chr4	48341595	48426198	+	chr4	48340296	48340565	-1165	HCP	0.189	0.003
33	572	Hypermethylated in glucose-treated	OR5B17	NM_001005489	chr11	58358124	58359069	-	chr11	58359703	58360169	-1812	LCP	0.188	0.003
34	755	Hypermethylated in glucose-treated	BRIX1	NM_018321	chr5	34915714	34925682	+	chr5	34916102	34916349	512	HCP	0.188	0.010
35	628	Hypermethylated in glucose-treated	SGF29	NM_138414	chr16	28553927	28591790	+	chr16	28553983	28554360	245	ICP	0.188	0.008
36	818	Hypermethylated in glucose-treated	ENY2	NM_020189	chr8	109334322	109345960	+	chr8	109334366	109334849	286	HCP	0.187	0.002
37	665	Hypermethylated in glucose-treated	LOC339807	NR_034023	chr2	64607311	64616482	+	chr2	64607285	64607787	225	LCP	0.184	0.001
38	837	Hypermethylated in glucose-treated	PBX3\|PBX3	NM_001134778\|NM_006195	chr9\|chr9	125748198\|125747337	125967376\|125967376	+\|+	chr9	125747707	125748219	-235\|626	HCP\|HCP	0.183	0.003
39	781	Hypermethylated in glucose-treated	HCP5	NR_040662	chr6	31463179	31465809	+	chr6	31462665	31463549	-72	ICP	0.182	0.001
40	706	Hypermethylated in glucose-treated	RNU12	NR_029422	chr22	42615244	42615393	+	chr22	42615563	42615824	450	HCP	0.182	0.003
41	616	Hypermethylated in glucose-treated	NSMCE3	NM_138704	chr15	29268148	29269816	-	chr15	29269331	29270001	-1518	HCP	0.181	0.003
42	617	Hypermethylated in glucose-treated	CAPN3	NM_173089	chr15	42404778	42412317	+	chr15	42404356	42405061	-70	LCP	0.179	0.002
43	743	Hypermethylated in glucose-treated	SMARCAD1\|SMARCAD1\|SMARCAD1	NR_045644\|NM_001128430\|NM_020159	chr4\|chr4\|chr4	94208083\|94207607\|94207844	94291292\|94291292\|94291292	+\|+\|+	chr4	94207139	94208447	-290\|186\|-51	HCP\|ICP\|HCP	0.176	0.001
44	663	Hypermethylated in glucose-treated	AGBL5-AS1\|AGBL5	NR_046730\|NM_021831	chr2\|chr2	27049682\|27051622	27050264\|27070622	-\|+	chr2	27050323	27051012	-986\|-954	HCP\|HCP	0.173	0.004
45	703	Hypermethylated in glucose-treated	MTMR3	NM_153051	chr22	29883168	30030868	+	chr22	29883238	29883494	198	HCP	0.172	0.004
46	669	Hypermethylated in glucose-treated	USP39	NM_001256728	chr2	85612102	85649284	+	chr2	85611470	85612582	-76	HCP	0.172	0.001
47	815	Hypermethylated in glucose-treated	MIR7705	NR_106992	chr8	100702967	100703024	-	chr8	100702968	100703663	-349	ICP	0.169	0.004
48	631	Hypermethylated in glucose-treated	PSMD7	NM_002811	chr16	74296774	74306288	+	chr16	74296353	74297039	-78	HCP	0.168	0.001
49	584	Hypermethylated in glucose-treated	CREBL2	NM_001310	chr12	12611832	12645108	+	chr12	12611526	12612233	48	ICP	0.167	0.001
50	751	Hypermethylated in glucose-treated	LINC01098	NR_028342	chr4	177728756	177990750	+	chr4	177728634	177728965	44	ICP	0.165	0.008
51	576	Hypermethylated in glucose-treated	NCAM1	NM_000615	chr11	112961246	113278436	+	chr11	112960748	112961223	-260	ICP	0.163	0.003
52	655	Hypermethylated in glucose-treated	CASP14	NM_012114	chr19	15049479	15058292	+	chr19	15049014	15049806	-69	LCP	0.163	0.002
53	696	Hypermethylated in glucose-treated	GDAP1L1\|GDAP1L1	NM_001256738\|NM_001256740	chr20\|chr20	44247098\|44247257	44280917\|44280917	+\|+	chr20	44247298	44247538	320\|161	ICP\|ICP	0.162	0.003
54	832	Hypermethylated in glucose-treated	ANXA1	NM_000700	chr9	73151730	73170394	+	chr9	73151508	73152316	182	LCP	0.162	0.004
55	689	Hypermethylated in glucose-treated	AP5S1	NM_018347	chr20	3820523	3825307	+	chr20	3820483	3820956	197	HCP	0.161	0.003
56	729	Hypermethylated in glucose-treated	MBNL1	NM_207294	chr3	152299404	152465780	+	chr3	152298155	152298671	-991	LCP	0.160	0.002
57	679	Hypermethylated in glucose-treated	MFSD6	NM_017694	chr2	190408354	190502315	+	chr2	190407480	190407939	-644	HCP	0.159	0.004
58	667	Hypermethylated in glucose-treated	MPHOSPH10	NM_005791	chr2	71130313	71150102	+	chr2	71130339	71130797	255	HCP	0.159	0.001
59	709	Hypermethylated in glucose-treated	VHL	NM_198156	chr3	10141634	10153670	+	chr3	10141611	10142087	215	HCP	0.159	0.005
60	759	Hypermethylated in glucose-treated	MAP3K1	NM_005921	chr5	56815072	56896151	+	chr5	56814203	56814952	-494	HCP	0.158	0.003
61	768	Hypermethylated in glucose-treated	KCNIP1	NM_014592	chr5	170504035	170736632	+	chr5	170503788	170504120	-81	HCP	0.155	0.010
62	756	Hypermethylated in glucose-treated	SLC1A3	NM_001289940	chr5	36606354	36688334	+	chr5	36605055	36605312	-1170	ICP	0.155	0.003
63	659	Hypermethylated in glucose-treated	PTOV1	NM_017432	chr19	49851119	49860744	+	chr19	49850074	49850758	-703	HCP	0.155	0.005
64	812	Hypermethylated in glucose-treated	NEFM	NM_001105541	chr8	24914941	24919093	+	chr8	24914329	24915227	-163	HCP	0.154	0.008
65	726	Hypermethylated in glucose-treated	RNF13	NM_183381	chr3	149812687	149962138	+	chr3	149812270	149813006	-49	ICP	0.154	0.003
66	707	Hypermethylated in glucose-treated	TRNT1	NM_182916	chr3	3126915	3149022	+	chr3	3126266	3127261	-151	HCP	0.153	0.002
67	597	Hypermethylated in glucose-treated	PABPC3	NM_030979	chr13	25096137	25098566	+	chr13	25095866	25096608	100	HCP	0.153	0.009
68	770	Hypermethylated in glucose-treated	TMED9	NM_017510	chr5	177592211	177596098	+	chr5	177591569	177592535	-159	HCP	0.153	0.002
69	541	Hypermethylated in glucose-treated	C1orf53	NM_001024594	chr1	197902551	197907367	+	chr1	197901324	197902705	-537	HCP	0.152	0.000
70	573	Hypermethylated in glucose-treated	MS4A5	NM_023945	chr11	60429588	60447792	+	chr11	60429752	60429997	286	LCP	0.151	0.002
71	614	Hypermethylated in glucose-treated	APOPT1	NM_032374	chr14	103562956	103592173	+	chr14	103563104	103563645	418	HCP	0.151	0.003
72	521	Hypermethylated in glucose-treated	MIER1	NM_001077703	chr1	66924894	66988619	+	chr1	66923607	66924077	-1052	HCP	0.151	0.004
73	512	Hypermethylated in glucose-treated	HES5	NM_001010926	chr1	2528744	2530245	-	chr1	2529844	2531379	-1868	HCP	0.149	0.000
74	774	Hypermethylated in glucose-treated	FOXC1	NM_001453	chr6	1610445	1613894	+	chr6	1610457	1610712	139	HCP	0.148	0.003
75	527	Hypermethylated in glucose-treated	RPL5	NM_000969	chr1	92832036	92841924	+	chr1	92830968	92831685	-710	HCP	0.146	0.004
76	611	Hypermethylated in glucose-treated	SUSD6	NM_014734	chr14	69611592	69715144	+	chr14	69610302	69610780	-1051	HCP	0.144	0.002
77	851	Hypermethylated in glucose-treated	RNF128	NM_024539	chrX	106693837	106797016	+	chrX	106692538	106693017	-1059	LCP	0.143	0.003
78	697	Hypermethylated in glucose-treated	WFDC10A	NM_080753	chr20	45629745	45631192	+	chr20	45628446	45629310	-867	ICP	0.143	0.001
79	844	Hypermethylated in glucose-treated	AR	NM_001011645	chrX	67568840	67730619	+	chrX	67567583	67568049	-1024	LCP	0.142	0.002
80	822	Hypermethylated in glucose-treated	FAM91A1	NM_144963	chr8	123768438	123815450	+	chr8	123767342	123767842	-846	HCP	0.141	0.002
81	786	Hypermethylated in glucose-treated	FAM229B	NM_001033564	chr6	112087470	112102790	+	chr6	112087119	112087598	-112	HCP	0.139	0.001
82	627	Hypermethylated in glucose-treated	KDM8\|KDM8	NM_001145348\|NM_024773	chr16\|chr16	27203974\|27203485	27221768\|27221768	+\|+	chr16	27203570	27204456	39\|528	HCP\|ICP	0.139	0.001
83	787	Hypermethylated in glucose-treated	NCOA7	NM_001199622	chr6	125919223	125932030	+	chr6	125917934	125918441	-1035	LCP	0.138	0.001
84	546	Hypermethylated in glucose-treated	CENPF	NM_016343	chr1	214603188	214664571	+	chr1	214602591	214603522	-132	HCP	0.136	0.001
85	676	Hypermethylated in glucose-treated	MTX2	NM_006554	chr2	176269394	176338025	+	chr2	176268517	176269874	-198	HCP	0.136	0.001
86	548	Hypermethylated in glucose-treated	ZNF678	NM_178549	chr1	227563518	227662463	+	chr1	227563081	227563976	10	ICP	0.133	0.003
87	858	Hypermethylated in glucose-treated	ASMT	NM_004043	chrY	1595454	1643081	+	chrY	1594921	1595187	-400	ICP	0.132	0.005
88	649	Hypermethylated in glucose-treated	NEDD4L	NM_001144969	chr18	58149332	58401540	+	chr18	58148954	58149642	-34	LCP	0.130	0.005
89	571	Hypermethylated in glucose-treated	ZDHHC5	NM_015457	chr11	57668001	57701187	+	chr11	57666914	57668155	-467	HCP	0.130	0.003
90	641	Hypermethylated in glucose-treated	TMEM99\|TMEM99\|TMEM99	NM_001195387\|NM_001195386\|NM_145274	chr17\|chr17\|chr17	40819091\|40819184\|40819121	40836274\|40836274\|40836274	+\|+\|+	chr17	40817874	40818655	-827\|-920\|-857	HCP\|HCP\|HCP	0.129	0.002
91	678	Hypermethylated in glucose-treated	PMS1	NM_001128144	chr2	189784084	189877629	+	chr2	189783721	189785665	609	HCP	0.128	0.001
92	823	Hypermethylated in glucose-treated	FER1L6	NM_001039112	chr8	123851986	124120061	+	chr8	123851173	123851524	-638	LCP	0.127	0.004
93	833	Hypermethylated in glucose-treated	SPATA31D4	NM_001145197	chr9	81928427	81934998	+	chr9	81928306	81928564	8	LCP	0.127	0.004
94	618	Hypermethylated in glucose-treated	FGF7	NM_002009	chr15	49423177	49487326	+	chr15	49423376	49423641	331	LCP	0.126	0.003
95	777	Hypermethylated in glucose-treated	HIST1H4K	NM_003541	chr6	27831173	27831527	-	chr6	27831183	27831428	-133	ICP	0.124	0.003
96	647	Hypermethylated in glucose-treated	C18orf61	NR_049896	chr18	12200778	12224710	+	chr18	12199479	12200272	-902	LCP	0.122	0.001
97	724	Hypermethylated in glucose-treated	PAQR9-AS1	NR_125393	chr3	142964057	143001090	+	chr3	142962839	142964624	-325	HCP	0.122	0.001
98	859	Hypermethylated in glucose-treated	TTTY19	NR_001549	chrY	8704471	8705283	+	chrY	8703178	8704810	-477	LCP	0.122	0.001
99	710	Hypermethylated in glucose-treated	OXNAD1	NM_138381	chr3	16265159	16306087	+	chr3	16265607	16266086	687	HCP	0.121	0.002
100	864	Hypermethylated in glucose-treated	CDY1\|CDY1B	NM_004680\|NM_001003895	chrY\|chrY	25622116\|25622116	25624901\|25624901	+\|+	chrY	25621911	25622591	135\|135	ICP\|ICP	0.121	0.004