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Colorectal CancerCancer or Adv Lesion
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FIT testCologuardFIT testCologuard
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Sensitivity73.8%92.3%27.7%46.4%
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Specificity93.4%84.4%94.9%86.6%
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Prevalence0.65%0.65%8.23%8.23%
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Positive Predictive Value (PPV)6.9%3.7%32.6%23.6%
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Number Needed to Screen (NNS)208.1166.543.826.2
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Cost of Test$16$509$16$509
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Cost of Followup (Colonoscopy)$800$800$800$800
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Cost to Test FIT NNS$3,330$105,925$701$22,300
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True Positives in FIT NNS1.01.31.01.7
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False Positives in FIT NNS13.632.32.15.4
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Cost of Followup (Colonoscopy)$11,667$26,667$2,456$5,119
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Screening $ / Positive Patient$14,996$106,073$3,157$16,408
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vs. FIT test7.15.2
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