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Personal WGS comparison table (30x WGS or greater, under $500):
V 2.8 – 3 Jan 2026
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formerlyDante LabsNebula Genomics
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CompanyDante OmicsDNA CompleteNucleus GenomicsSequencingtellmeGenYSEQ
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ProductWGtestPro, EliteWGS ^^Compreh ***UltraWGS , WGS+, ++
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gigabases90-90+, 300+90+90+~90~45. ~90, ~150
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Depth x30x-30x+, 100x+30x+30x+~30x~15x, ~30x, ~45x
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Length bp150150150150150100, 150
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Insert Size~300-400~300-400~350-400~325~200-400
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Price $$200 – 500$495, $995$499$399 ***$299$359, 399, 699
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LabIn-houseIn-house (was BGI)Boston, USAFTDNA, In-houseEurofinLatvia, In-house
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SequencerIllumina
Novaseq 6000		Ill Novaseq X,
MGI T7 / T10		Illumina Novaseq XMGI T7 v2.5,
Ill. Novaseq 6000		MGI T7 v2. 5
MGI T7 v2.5, DNB GS400
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SamplingSpit tube;
Tasso Blood		Wet SwabWet SwabWet SwabDry SwabDry Swab
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Turnaround **8-16+ weeks?12-14+ weeks6-8 weeks12-14 weeks4-6 weeks10+ weeks
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Based in ****ItalyNJ, USANYC, USACA, USASpainGermany
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Free Return ShipDHL worldwideUSA onlyUSA and ... Only ^^USA onlyUPS WorldwideNone
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FilesBAM, VCF,
FASTQ		CRAM, VCFCRAM, VCFs, RAW,
FASTQs		BAM, VCF, RAW,
FASTQ
FASTQ, gVCF pseudo
BAM, VCF, RAW, Y / MT Analysis
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Ref Model ^hs37d5hs38DHhs38DHhs38sEBI37h (GRCh37)hg38
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ReportsHealthHealth, Ancestry?HealthHealth, Ancestry
Health, Traits, Ancestry
Ancestry
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Recurring
Subscription		Optional;
$5-25/mth		$150 / year *$39/year$19, 39 or 129/mth *$20; free 1st yearn.a.
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Offerred2018-20242020-20252025-2020-2025-2020-
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Source:
https://facebook.com/groups/personalwgs
Randy Harr
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Key
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~
target is that number (RAW)
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+
guarantees that number and often delivers more (mapped)
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-
strives to reach that number but may or may not achieve it (RAW)
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RAWThe microarray RAW format files (e.g. 23andMe API or similar) with over 1 million values. Use DNA Kit Studio to make smaller.
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hs38sSequencing uses GCA_000001405.15_GRCh38_no_alt_plus_hs38d1_analysis_set.fna.gz with unique 22_KI270879v1_alt alt contig tacked on
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*Nebula no longer bills extra for a first year subscription and has a higher base price as a result.
Sequencing gives first 1 mth subscription free but $39/mth after billed yearly.
Both auto enroll and renew. So you must cancel to avoid further billing.
If Nebula cannot bill the first payment, you do not get your results when ready.
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**
Throughout 2023 and 2024, the delivery times have varied widely. Some over 12 months late and still counting
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***Regular is $399, Expedited / Advanced (6-8weeks) is $599, Professional Expedited (2-3 weeks) w/ 3 mth subscription is $999. Often bundle regular (comprehensive) with expedited for $399.
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****Roughly Aug 2023-Aug 2024 Dante USA orders were fulfilled by FamilyTreeDNA in Houston on their Illumina Novaseq 6000 sequencer. Roughly Spring 2024 onwards, Sequencing.com USA orders are fulfilled by FTDNA in Houston. Initially on an Illumina Novaseq 6000; now an MGI DNB T7. As of Spring 2024, Nebula has their own in-house MGI DNB T10 in a new NJ lab instead of sending to the BGI lab in China. YSEQ has their own DNB400 but also does bulk runs on a T7v2.5 in a lab nearby (was Latvia).
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^
For reference model codes, see https://bit.ly/34CO0vj
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^^
Currently, only from / to USA, Canada, Ireland, UK, Germany, Italy, India and Australia.
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Dante Labs
Dante Labs appears out of business as of Sep 2024. The staff has been laid off. The founders are trying to
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resurrect as Dante Omics and still taking orders online. Thousands of existing orders yet to be sequenced.
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Nebula Genomics
DNA Complete / Nebula stopped delivering for 6+ months. Some deliveries are less than 30 WGS results.
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New results are appearing consistently good now that they have a stable, outside vendor (Dec 2025)
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