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GroupStartDateEndDateProgressDuration (in seconds)FinishedRecordedDateQ1.2Q2.2Q2.3Q2.4Q2.5Q2.6#1_1Q2.6#1_2Q2.6#1_3Q2.6#1_4Q2.6#1_5Q2.6#1_6Q2.6#1_7Q2.6#1_8Q2.6#1_9Q2.7Q2.8Q2.9Q2.10Q2.11Q2.12Q2.13Q2.14_1Q2.15Q2.15CQ2.15NQ2.16Q2.17Q2.18Q2.18CQ2.19Q2.19CQ2.19NQ2.20Q2.20CQ2.21Q2.21CQ2.21NQ2.22Q2.22CQ2.23Q2.23CQ2.23NQ2.24Q2.24CQ2.25Q2.25CQ2.25NQ2.26Q2.26CQ2.27Q2.27CQ2.27NQ2.28Q2.29_1Q2.29_2Q2.30_1Q2.30_1NQ2.30_2Q2.30_2NQ2.31Q2.32Q2.33Q3.1_1Q3.1_2Q3.1_3Q3.1_4Q3.1_5Q3.2Q3.3Q3.4Q3.5Q3.6Q3.7Q3.8Q3.9Q3.10Q4.1_1Q4.1_1NQ4.1_2Q4.1_2NQ4.2Q4.3Q4.4Q4.5Q4.6_1Q4.6_2Q4.6_3Q4.6_4Q4.6_5Q4.6_6Q4.6_7Q4.6_8Q4.6_9
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GroupStart DateEnd DateProgressDuration (in seconds)FinishedRecorded DatePlease print out COVID-19 HCT Group Consent Form if you would like a copy of it for your files.



If you do not wish to take part in the research, close this website address. If you wish take part in the research, follow the directions below:



I acknowledge that I am 18 years of age or older and have read and understand the information. I agree to take part in the research, with the knowledge that I am free to withdraw my participation without penalty.



Click on the "I Agree" button to confirm your agreement to take part in the research.		I consent to being contacted by 1Day Sooner for follow-up studies related to this surveyIn what way did you first hear about the idea of a COVID-19 infection study?What was your first reaction to the idea of a COVID-19 infection study?When did you decide you wanted to enroll in a COVID-19 infection study? I.e. Is it a decision you made immediately or did you take some time to think about it?Please indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I want to help others and potentially save livesPlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I feel helpless and this is a way to do something positivePlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I was curious about COVID-19Please indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I wanted to be part of a clinical trialPlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I wanted to contribute to the progress of medicinePlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I wanted to find out more about my own healthPlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I wanted to receive financial reimbursement for participatingPlease indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I wanted to be guaranteed access to critical care should I be infected with COVID-19Please indicate how important the following factors are in your decision to volunteer for a contr... - The following factor was important to me when considering my decision to volunteer for a controlled COVID-19 infection study - I am likely to be infected with COVID-19 anywayAre there any other factors that influenced your decision to volunteer for a controlled COVID-19 infection study?What are the three most important factors in your decision to participate? Please select three optionsPlease indicate the extent to which you agree with the following statement: COVID-19 is of similar severity as influenza (the flu)What do you think are the main risks and burdens of being in a controlled COVID-19 infection study?Which of these risks and burdens concern you the most?Which of these risks and burdens concern you the least?What do you think are the main benefits of being in a controlled COVID-19 infection study?How risky do you think a COVID-19 challenge study is overall, on a scale of 1 to 10? This refers to the risk to your own health from participating — not a risk to others, and not including how likely you are to be infected with COVID-19 outside of a trial. - Level of personal riskWhat is your perception of the risk of developing conditions during a COVID-19 challenge trial that are severe enough to require critical care such as a ventilator?Q2.15 CategoriesQ2.15 Risk per 100KHow much care do you predict you would receive from the researchers if you were to become sick?How much care do you think you have the right to receive from the researchers if you were to become sick?How would you rate your risk of dying should you become infected with COVID-19 during the course of a challenge trial, if you were to participate?Q2.18 CategoriesWhat is your perception of your risk of dying should you become infected with COVID-19 during a challenge trial, if you were to participate?Q2.19 CategoriesQ2.19 Risk per 100KCompared to your expected risk in participating in a COVID-19 challenge trial, to what extent would you be willing to accept greater risk as a participant if you believed the benefits to society would be significant?Q2.20 CategoriesWhat is the highest risk of death that you would accept to participate in a COVID-19 challenge trial if you believed such a trial was likely to confer significant benefits to society?Q2.21 CategoriesQ2.21 Risk per 100KHow would you rate your risk of becoming infected with COVID-19 during the course of your everyday life in the next six months?Q2.22 CategoriesWhat is your perception of your risk of becoming infected with COVID-19 during the course of your everyday life in the next six months?Q2.23 CategoriesQ2.23 Risk per 100KHow would you describe your risk of not being put on a ventilator or receiving other scarce treatments (such as dialysis machines) that you need to survive in your current living area because of the COVID-19 surge in demand for health services?Q2.24 CategoriesWhat is your perception of your risk of not being put on a ventilator or receiving other scarce treatments (such as dialysis machines) that you need to survive in your current living area because of the COVID-19 surge in demand for health services?Q2.25 CategoriesQ2.25 Risk per 100KHow would you rate your risk of dying from COVID-19 during the course of your everyday life in the next six months?Q2.26 CategoriesWhat is your perception of your risk of dying from COVID-19 during the course of your everyday life in the next six months?Q2.27 CategoriesQ2.27 Risk per 100KHow many people do you think will have been infected with COVID-19 worldwide, before 2021?How many people do you think will die as a result of COVID-19 before 2021? - As a direct resultHow many people do you think will die as a result of COVID-19 before 2021? - As an indirect result This might include people who die of conditions that clinicians must neglect in order to prioritize COVID-19, halted economic development, ensuing famine, etc.Your participation in human challenge trials... - How likely do you think it is that your participation in a COVID-19 human challenge trial leads to accelerated vaccine development?Q2.30_1 CategoriesYour participation in human challenge trials... - How likely do you think it is that your participation in a COVID-19 human challenge trial leads to saving people’s lives?Q2.30_2 CategoriesDid you talk to anyone about whether you should join a potential human challenge study?If yes, who did you talk to?What did they think about it?Please indicate whether you believe the following statements are true or false. This section does not require any additional outside research, and is simply designed to capture your current understanding of how a human challenge trial may work. - Participants in a human challenge trial would be exposed to the novel coronavirus (COVID-19)Please indicate whether you believe the following statements are true or false. This section does not require any additional outside research, and is simply designed to capture your current understanding of how a human challenge trial may work. - Participants in a human challenge trial will be isolated from their household and general public in a specialized health facilityPlease indicate whether you believe the following statements are true or false. This section does not require any additional outside research, and is simply designed to capture your current understanding of how a human challenge trial may work. - Participants in a human challenge trial might infect their family members with COVID-19Please indicate whether you believe the following statements are true or false. This section does not require any additional outside research, and is simply designed to capture your current understanding of how a human challenge trial may work. - Participants are eligible for a human challenge trial if they have already tested positive for COVID-19Please indicate whether you believe the following statements are true or false. This section does not require any additional outside research, and is simply designed to capture your current understanding of how a human challenge trial may work. - All participants will receive the candidate COVID-19 vaccineHave you ever participated in research studies before?Since you have participated in research studies before, please tell us more about that experience. What was the purpose of the study?How were your prior experiences with research studies?How would a human challenge study be different from previous studies you have participated in?Have you ever donated blood before?Have you ever donated a significant amount of money to charity?Are you a registered bone marrow donor?Are you a registered deceased organ donor?Have you ever been a living kidney or liver donor?Future COVID-19 human challenge studies - If a COVID-19 human challenge trial moves forward and you are asked to participate, what is the likelihood you agree to participate?Q4.1_1 CategoriesFuture COVID-19 human challenge studies - If an effective treatment for COVID-19 is discovered, and a COVID-19 human challenge trial moves forward, what is the likelihood you agree to participate?Q4.1_2 CategoriesIf a COVID-19 human challenge trial moves forward and you are asked to participate, what would make you NOT want to enroll in such a study?How likely do you think it is that some people participating in the study might not tell the researchers things that could disqualify them from participating? For example, not fully revealing drug or alcohol consumption, or personal history that may exclude them from participating otherwise.How do you think other people would perceive your enrollment in a COVID-19 challenge trial?Where others (e.g., your parents or colleagues) may be upset about your enrollment, what would be helpful, if anything, for us or the trial team to do to pre-empt or address these reactions? For example, providing you with information about the study to share with others?Please indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - Partner/SpousePlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - ParentPlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - ChildPlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - SiblingPlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - Close friendPlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - Work colleaguePlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - HousematePlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - Remote friendPlease indicate whether any of your personal connections have been infected with COVID-19. A severe case is defined here as requiring hospitalization or admission to an intensive care unit (ICU). - Extended family
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Volunteer6/10/20 11:006/10/20 11:13100760True6/10/20 11:13I AgreeYesthrough scientists on twitterit's necessary for humanityfor humanityStrongly agreeStrongly agreeStrongly disagreeStrongly disagreeStrongly agreeStrongly disagreeStrongly disagreeNeither agree nor disagreeSomewhat agreenoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeunsure outcomedeathinfection as most will probably get itmore quickly advancing science31 in 500 (0.2%)6200A lotA great deal4 - There is a moderate risk to me41 in 100 (1%)81000331 in 1,000 (0.1%)5100551 in 100 (1%)81000221 in 1,000 (0.1%)5100221 in 1,000 (0.1%)5100Between 5 million and 20 million infections 62282945171327Fairly likely6Fairly likely6NoTrueTrueFalseFalseTrueNeverNeverPrefer not to sayNoYesNoFairly likely6Fairly likely6can't think of anythingSomewhat likelyNeutralexplain risks and benefitsN/AN/AN/AN/AN/AN/AN/ASevereN/A
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Volunteer6/10/20 11:016/10/20 11:181001020True6/10/20 11:18I AgreeYesI can't remember, but I believe it was through news media.I thought it is a great way to speed up vaccine research, since I believe informed consent trumps the ethical issues associated with voluntary endangerment of someone's health. Immediately.Somewhat agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeSomewhat agreeSomewhat agreeSomewhat disagreeStrongly agreeNeither agree nor disagreeGetting a vaccine sooner as a result. I wanted to contribute to the progress of medicine,I wanted to be guaranteed access to critical care should I be infected with COVID-19,Another factor I identified aboveSomewhat disagreeBoth the risks of an experimental vaccine and the risk of potentially contracting a severe form of COVID-19. Insofar as burdens, avoiding people I love for fear of exposing them to COVID.Contracting COVID-19. Vaccine side effects.Helping the advancement of vaccine research and a guarantee of availability of effective care.75 in 100 (5%)95000A lotA great deal331 in 1,000 (0.1%)5100331 in 100 (1%)810004 - There is a moderate risk to me433 in 100 (33%)1233000331 in 100 (1%)81000221 in 10,000 (0.01%)310Between 20 million and 50 million infections 24478704484148Somewhat likely5Somewhat likely5YesMy partner.He thought it was a reasonable decision to make in light of my assessment of the risks, but not one he would make himself due to having an underlying health condition.TrueTrueTrueFalseTrueMore than onceRisks of alcohol consumption (in multiple studies). PositiveThere are non-trivial risks to me that are immediate, as opposed to incidental, as a result of my participation. NeverYes, I have on occasionNoNoNoSlightly likely5Extremely likely7The risk of contracting a severe form of COVID-19. Somewhat likelySomewhat positivelyGuaranteeing access to the best available treatment if I am to get sick. N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:006/10/20 11:211001271True6/10/20 11:21I AgreeYesMarginal Revolution (Prof. Cowen's blog)I thought it might be a good ideaImmediatelyStrongly agreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeStrongly agreeSomewhat agreeSomewhat agreeSomewhat agreeStrongly agreeI want to help others and potentially save lives,I wanted to find out more about my own health,I am likely to be infected with COVID-19 anywayStrongly disagreeDeathNoneDeathHelping out31 in 5,000 (0.02%)420None at allA little331 in 1,000 (0.1%)51007 - I would accept a seriously greater level of risk71 in 100 (1%)810004 - There is a moderate risk to me41 in 100 (1%)810001 - There is no risk to me11 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 5 million and 20 million infections 654181809944Neither likely nor unlikely4Neither likely nor unlikely4NoTrueTrueTrueTrueFalseNeverOnceNo, I have notUnsure/I don’t knowYesNoExtremely likely7Extremely likely7Logistical problems, like not being able to find appropiate lodging/transportation means Somewhat likelyNeutralproviding me with information about the study to share with othersN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:066/10/20 11:21100924True6/10/20 11:21I AgreeYesI heard about this on Facebook and Instagram I thought it was great and a good way to get money.I don’t have preexisting conditions. If I can live in a quarantine facility after being exposed in order to protect my parents it would be great Neither agree nor disagreeSomewhat disagreeSomewhat agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeI want to get the vaccine for free if possible because I have to pay 40 bucks for a flu shot and it’s pricey. I was curious about COVID-19,I wanted to be part of a clinical trial,I wanted to receive financial reimbursement for participatingDisagreeI feel one risk is infecting my parents but this will be mitigated by housing volunteers in a quarantine building.Infecting my parents because they’re 70 years old Nothing I can get the jab for free31 in 500 (0.2%)6200A littleA little1 - There is no risk to me11 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk45 in 100 (5%)950005550 in 100 (50%)13500001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me11 in 10,000 (0.01%)310More than 250 million infections34033133681393Somewhat likely5Neither likely nor unlikely4YesI talked to my friend They thought it was a good idea TrueTrueTrueFalseFalseMore than onceI took psychological surveys in college and I also went into a cat scanner to get a brain scan. PositiveI will be in a quarantine center instead of sitting in the psych department for an hour OnceNo, I have notNoUnsure/I don’t knowNoExtremely likely7Fairly likely6If I have to live with my mom during the test NeutralSomewhat negativelyTelling my mom she’s not at risk from me taking the test because she’s 70 years old N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:036/10/20 11:231001191True6/10/20 11:23I AgreeYesI heard about it online via social media.I am very interested in participating.Immediately Neither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeNoI wanted to be part of a clinical trial,I wanted to find out more about my own health,I wanted to receive financial reimbursement for participatingNeither agree nor disagreeThe symptoms of COVID NoneNoneFinancial reimbursement51 in 100,000 (0.001%)11A great dealA great deal4 - There is a moderate risk to me41 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk71 in 100,000 (0.001%)114 - There is a moderate risk to me41 in 50,000 (0.002%)224 - There is a moderate risk to me41 in 100,000 (0.001%)114 - There is a moderate risk to me4Less than 0.001%00Between 2 million and 5 million infections2000020000Neither likely nor unlikely4Neither likely nor unlikely4NoTrueTrueTrueTrueTrueMore than onceVeterans research studies at NIHExtremely positiveWould be differentMore than onceNo, I have notUnsure/I don’t knowYesNoExtremely likely7Extremely likely7I would enroll.NeutralNeutralInformationN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:036/10/20 11:231001224True6/10/20 11:23I AgreeYesAn article I found online.I was interested, and I thought about how low-risk I was, and I would like to do it.
I took a few minutes to think about it.Strongly agreeStrongly agreeStrongly disagreeNeither agree nor disagreeSomewhat agreeSomewhat disagreeSomewhat disagreeNeither agree nor disagreeSomewhat disagreeI am healthy and have a strong body; I am in a low-risk group and I feel I am a good, low-risk-of-death candidate for a study like this.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,Another factor I identified aboveSomewhat disagreeThe time away from home, work, and loved ones. There is also the risk of complications, physical suffering, and death.Being away from work and loved ones.Risk of suffering.Guaranteed access to care310 in 100 (10%)1010000A lotA lot221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk45 in 100 (5%)950002220 in 100 (20%)11200004 - There is a moderate risk to me450 in 100 (50%)13500001 - There is no risk to me11 in 250 (0.4%)7400Between 100 million and 250 million infections51659389253728Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseOnceOnline surveysNeither positive nor negativeIn-personMore than onceYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7The risk of losing my home/being financially unsupported if I take the leave of absence from work.NeutralNeutralProviding information about the study is a good idea. N/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:006/10/20 11:241001420True6/10/20 11:24I AgreeYesI heard about it from an online news articleIf such an experiment can save lives by accelerating the production of a vaccine, it should be carried out.Immediately on hearing the idea.Strongly agreeStrongly disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat disagreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayStrongly disagreeThe medical risk from being infected. Side effects from the vaccine. Psychological harms from being isolated.Dying from infectionIsolation: I'm already isolatedSaving lives31 in 500 (0.2%)6200A great dealA great deal221 in 10,000 (0.01%)3107 - I would accept a seriously greater level of risk75 in 100 (5%)950004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 10,000 (0.01%)310221 in 50,000 (0.002%)22Between 100 million and 250 million infections30591771057017Somewhat unlikely3Extremely unlikely1YesMy familyThey think it's a good ideaTrueTrueFalseFalseFalseMore than onceStandard behavioral economics studiesNeither positive nor negativeIt was not medical, and did not involve risk.NeverNo, I have notYesYesNoExtremely likely7Slightly likely5I would not participate if I am unable to reach the test siteExtremely unlikelyFairly positivelyDiscuss the project openly in national media N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:076/10/20 11:241001000True6/10/20 11:24I AgreeYesThe news - I heard about it on the radio. Cautious optimism - it sounded like it could be a good idea and helpful for the effort. I took some time, but it was pretty quick - once I saw a link to sign up I jumped on it. Strongly agreeSomewhat agreeStrongly disagreeNeither agree nor disagreeSomewhat agreeSomewhat disagreeStrongly disagreeStrongly disagreeStrongly disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeLoss of income, possible negative health effects Loss of incomeNegative health effects Being able to help41 in 1,000 (0.1%)5100A moderate amountA great deal4 - There is a moderate risk to me41 in 1,000 (0.1%)5100551 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 100 (1%)81000221 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 20 million and 50 million infections 26074077289383Somewhat unlikely3Somewhat unlikely3NoFalseTrueFalseFalseFalseNeverMore than onceYes, I have on occasionUnsure/I don’t knowYesNoFairly likely6Fairly likely6Perceived riskiness of trial - do the operators seem trustworthy? Somewhat likelySomewhat positivelyN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:016/10/20 11:241001413True6/10/20 11:24I AgreeYesOura ring emails for the Stanford studyHappy to help, thought it was a great ideaimmediatelyStrongly agreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeSomewhat disagreeNeither agree nor disagreeNeither agree nor disagreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to find out more about my own healthDisagreeSchedule disruption, isolationisolationN/AHelping others21 in 100 (1%)81000A littleNone at all1 - There is no risk to me11 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk41 in 100 (1%)810002210 in 100 (10%)1010000221 in 10,000 (0.01%)3101 - There is no risk to me11 in 10,000 (0.01%)310Between 20 million and 50 million infections 40364775683122Somewhat likely5Somewhat likely5YesWifeThought it was a good ideaTrueFalseTrueFalseFalseOnceJust a few psychological studies in college, nothing like thisSomewhat positiveThis one has medical effects, vs psychological ones which don'tMore than onceYes, I donate annuallyUnsure/I don’t knowYesNoFairly likely6Fairly likely6Just timeline and if I'd be able to still work some (remotely) — making sure it doesn't disrupt my other obligations too muchSomewhat unlikelyFairly positivelyDon't think anyone would be too upsetN/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:076/10/20 11:251001072True6/10/20 11:25I AgreeYesIt was posted by a friend online Science is good. Vaccines are good. Immediately Strongly agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeStrongly agreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeNeither agree nor disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeProbably slightly less than getting it outside of a study. I am not terribly concerned. Although I know there are anecdotal cases of people with "no underlying disorders" getting really sick, I feel like my health status makes me a good candidate and I am not terribly concerned about my own safety. I am, however, concerned about others. n/a Helping find a vaccine quickly 51 in 500 (0.2%)6200A moderate amountA moderate amount221 in 50,000 (0.002%)224 - I would accept a moderately greater level of risk41 in 10,000 (0.01%)3104 - There is a moderate risk to me41 in 1,000 (0.1%)5100221 in 100,000 (0.001%)1122Less than 0.001%00More than 250 million infections81085848153088Fairly likely6Fairly likely6NoTrueTrueTrueTrueFalseNeverOften Yes, I donate annuallyYesYesNoFairly likely6Fairly likely6Can't thing of anything. I guess if the trial risks bursting into flames I might rethink it. Fairly likelyVery positivelyThat the trial would speed up vaccine development N/AN/AN/AN/AN/AN/AN/ASevereN/A
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Volunteer6/10/20 11:026/10/20 11:251001372True6/10/20 11:25I AgreeYesI came across it on Twitter and Marginal Revolution (a blog)It seems like a sensible thing to do, given the circumstances.Shortly after hearing about itStrongly agreeSomewhat agreeSomewhat disagreeSomewhat disagreeNeither agree nor disagreeNeither agree nor disagreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeMeaningful way to contribute to societyI want to help others and potentially save lives,I am likely to be infected with COVID-19 anyway,Another factor I identified aboveDisagree1. Impact on my family (I'm the father of two children)
2. Potential short- or long-term health consequences
3. Financial impact		Impact on my familyFinancial impactBringing a vaccine to market sooner than traditional methods71 in 500 (0.2%)6200A lotA moderate amount331 in 1,000 (0.1%)5100331 in 100 (1%)810004 - There is a moderate risk to me420 in 100 (20%)1120000331 in 10,000 (0.01%)310221 in 10,000 (0.01%)310Between 100 million and 250 million infections40409591735312Extremely likely7Fairly likely6NoTrueTrueFalseFalseFalseOnceSome child behavioral psychology study when I was growing upNeither positive nor negativeMuch higher level of riskNeverYes, I donate annuallyNoNoNoFairly likely6Extremely likely7Family concernsSomewhat likelySomewhat positivelyUnsureN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:006/10/20 11:261001569True6/10/20 11:26I AgreeYesI first heard about the human challenge trial from a news article.This sounds like a good potential idea to expedite the production of a COVID-19 vaccine; I am in the desired age group and in very good health, and would be able to participate.Took a few days to think about itStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeSomewhat disagreeNeither agree nor disagreeSomewhat disagreeStrongly disagreeEliminating the possibility of contracting covid through other means and spreading it to higher-risk family membersI feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicine,Another factor I identified aboveSomewhat agreeDeath; permanent respiratory damage; side effects from vaccinePermanent respiratory damage, because I am a runnerDeath (for my age and level of health)Contributing to science, helping researcher's efforts pay off; intrinsically interested in the research process since I am a graduate student researcher in the social sciences31 in 100 (1%)81000A great dealA great deal221 in 10,000 (0.01%)310221 in 100 (1%)810003320 in 100 (20%)11200001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me11 in 100,000 (0.001%)11Between 20 million and 50 million infections 1022455899933Somewhat likely5Somewhat likely5Yespartner, parentsDidn't have a strong opinion one way or anotherTrueTrueFalseFalseFalseVery Oftennumerous studies examining a variety of psychological constructsExtremely positivebiological study; being injected with a vaccine/virus; never participated in a clinical trial beforeOften Yes, I have on occasionUnsure/I don’t knowYesNoSlightly likely5Slightly unlikely3concern about the safety of the vaccine; risk of permanent organ damage as a result of getting covidSomewhat likelySomewhat positivelyproviding information about the study, working with participants to ensure it does not impact work/degree progressN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:016/10/20 11:261001520True6/10/20 11:26I AgreeYesI don't recall exactly, I think I saw it in a friend's post in social mediaI think it is great, taking into account the heavy tool we are paying in terms of human lives and economy damagesIt was a quick decision for meStrongly agreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeSomewhat agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeNoI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeBeing particularly sensitive to the effect of the virus, my inmune system not being able to cope with the infectionDyingBeing sick for a few daysQuicker reaction if things go wrong and my health deteriorarse seriously510 in 100 (10%)1010000A lotA lot221 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)5100331 in 100 (1%)81000221 in 10,000 (0.01%)310221 in 100,000 (0.001%)11Between 5 million and 20 million infections 500618810000000Somewhat likely5Somewhat likely5NoTrueFalseFalseFalseFalseNeverVery OftenYes, I donate annuallyYesYesNoFairly likely6Fairly likely6I cannot think of anything right nowSomewhat likelyFairly positivelyInfo and expectations on timing and risksN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:026/10/20 11:271001508True6/10/20 11:27I AgreeYesDont remember exactly- probably ctv newsJust want to do my part to get society back to normalImmediatelyStrongly agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeStrongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeNoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywaySomewhat agreeRisk to my familyNot much, i believe myself and my family have likely already been infected NoneImproving science around Covid-19 and getting societ back to normal21 in 250 (0.4%)7400None at allA moderate amount1 - There is no risk to me11 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 100 (1%)810005550 in 100 (50%)1350000221 in 100 (1%)810001 - There is no risk to me1Less than 0.001%00Between 100 million and 250 million infections13895481015227Fairly likely6Extremely likely7YesWifeSupportive of helping societyFalseFalseTrueTrueFalseNeverMore than onceYes, I donate annuallyYesYesNoFairly likely6Extremely likely7Family changing mind; or necessity to self isolate during trial; or if work disagreesExtremely likelyFairly positivelyInformation on requirements to shareN/AN/AN/AN/AN/AMildN/AN/AMild
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Volunteer6/10/20 11:016/10/20 11:281001638True6/10/20 11:28I AgreeYesOnline article, I believe by Yahoo.I was curious, but not concerned.Immediately.Strongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeI own a business that has been greatly impacted by COVID-19, and can't get back to doing business right until a vaccine is ready.I want to help others and potentially save lives,I was curious about COVID-19,I wanted to contribute to the progress of medicineDisagreeFinding out that I have a previously unknown condition that would be problematic if I were infected with COVID-19.
Spreading it to others if proper precautions weren't taken.		Finding out about the problematic condition.Spreading it. If I were to do this, I could easily self-isolate and get through it.Being able to speed up development of a vaccine. 41 in 100 (1%)81000A lotA lot221 in 1,000 (0.1%)5100555 in 100 (5%)950004 - There is a moderate risk to me410 in 100 (10%)10100002210 in 100 (10%)1010000221 in 1,000 (0.1%)5100Between 5 million and 20 million infections 18933414112358Somewhat likely5Somewhat likely5YesA number of friends.They understood. Some thought it was just a little crazy. But nobody thought it was ridiculous.TrueTrueFalseFalseFalseOnceIt was a sleep study when I was in my 20s.Somewhat positiveThere was no risk of illness or death from the sleep study.NeverYes, I donate annuallyYesYesNoExtremely likely7Extremely likely7Extreme inconvenience in isolating myself. I need to be able to keep working with my company online. Somewhat likelySomewhat positivelyMaking clear what attention and care a participant gets during the trial.N/AN/AN/AN/AMildN/AN/ASevereN/A
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Volunteer6/10/20 11:026/10/20 11:291001612True6/10/20 11:29I AgreeYesThrough a Google search on vaccines related to COVID and reference to this organization.That I wanted to be a part of this solution.ImmediatelyStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly agreeStrongly agreeStrongly disagreeNeither agree nor disagreeStrongly disagreeStrongly agreeNoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayNeither agree nor disagreeI could get sick, which could result in death, but the information would be collected in a manner which could save multiples of lives more than my own.DeathDeathThat information can be extracted that can result in saving peoples lives.21 in 1,000 (0.1%)5100A lotA moderate amount331 in 50,000 (0.002%)226610 in 100 (10%)1010000221 in 1,000 (0.1%)5100221 in 50,000 (0.002%)221 - There is no risk to me1Less than 0.001%00Between 50 million and 100 million infections40298215990179Somewhat likely5Extremely likely7YesPartnerConcerned, but understandingTrueTrueTrueFalseFalseNeverOften No, I have notYesYesNoExtremely likely7Extremely likely7If it would cost my employment statusSomewhat likelyFairly positivelyNoN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:046/10/20 11:291001521True6/10/20 11:29I AgreeYesI saw this as a link on Reddit.comIt’s amazing and I was immediately inImmediately decidedStrongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeSomewhat agreeStrongly disagreeStrongly disagreeStrongly agreeTo help lead to a vaccine, hopefully faster than any other trials wouldI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayStrongly agreeI do not believe covid is risky to me, in fact I would like to be infected and have it over with. Biggest risk to me would be if I had to live somewhere else during the trial, since I have a 7yr old daughter I care for. NoneNoneHelping get to an approved vaccine for the general population faster than would otherwise be possible 11 in 50,000 (0.002%)22A moderate amountA moderate amount1 - There is no risk to me11 in 100,000 (0.001%)114 - I would accept a moderately greater level of risk41 in 100,000 (0.001%)117 - The risk to me is extremely high7Almost certainly (95% or greater)16950001 - There is no risk to me110 in 100 (10%)10100001 - There is no risk to me1Less than 0.001%00Between 20 million and 50 million infections 20218882169086Extremely likely7Fairly likely6YesFamilyThey did not love the idea TrueFalseTrueFalseTrueNeverMore than oncePrefer not to sayNoYesNoExtremely likely7Extremely likely7Having to live away from my home Fairly unlikelySomewhat negativelyIf everyone receives the vaccine before becoming infected with covid MildN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:056/10/20 11:291001420True6/10/20 11:29I AgreeYesMarc Lipstitch interview. I have been following him pretty closely and I liked his take on this idea. Mostly I took his words and did my own research on the topic, talked to my husband who is a Doctor, and felt like this was a really solid idea. Positive. I believe people should be allowed to make calculated risks that benefit others. We do this in many other areas of life, but their is such a complicated and ugly history with medicine that we have completely moved away from this model. Pretty immediately. I listened to the podcast and liked the idea, did my own research, and talked to my husband. It's not the right call for everyone, but I think it is the right call for me. Strongly agreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeI'm a PhD scientists. I support GOOD science. I can read the data and see that I am very low risk for developing serious complications due to COVID. But I could use science and aid science in making a difference. That matters. I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveStrongly disagreeI think you need to make sure people really understand that they are consenting to unknown risks. We still really do not understand this virus. So the idea of consent in a situation like this is complicated. I feel the most ethically comfortable with consenting highly educated people, who are particularly educated regarding consent, research, and risk. The ability to ethically conduct this type of research when we don't really know the risk. What does this mean for the idea of consent? It's ethically tricky. I'm comfortable with my personal ability to make that assessment, but I get worried about others ability to fully make that consent. Potential effects of COVID, I'm seriously not worried about myself and COVID. Faster development of a vaccine and the potential to develop a vaccine even if we continue to attempt to radically control exposure in this country. 21 in 500 (0.2%)6200A moderate amountNone at all221 in 10,000 (0.01%)310555 in 100 (5%)950004 - There is a moderate risk to me410 in 100 (10%)10100001 - There is no risk to me11 in 50,000 (0.002%)22221 in 100,000 (0.001%)11Between 5 million and 20 million infections 603473210000000Extremely likely7Extremely likely7YesHusbandNot in favor. He thinks the history of challenge trials in medicine is too ugly and complicated to open this again. TrueTrueFalseFalseFalseVery OftenI'm a psych researcher. This is what I do all day every day. Extremely positiveThis is medical and the risks are FAR greater than what I deal with. Very OftenYes, I have on occasionYesYesNoFairly likely6Fairly likely6I'm currently pregnant. I need to have given birth and figured out if I can breastfeed or not. If I can (couldn't with my first) this would delay my ability to participate until I am done breastfeeding. NeutralNeutralI think I would not share this information with anyone else but my spouse. I really don't think it's any of their business. I'm not doing it for them. N/AN/AN/AMildN/AN/AN/ASevereN/A
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Volunteer6/10/20 11:026/10/20 11:291001641True6/10/20 11:29I AgreeYesRead facebook ad looking for people willing to volunteer I would be interested in participating immediately Strongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeStrongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeTime away from familynoneminehelping others533 in 100 (33.3%)1233000A great dealA lot5533 in 100 (33.3%)12330004 - I would accept a moderately greater level of risk410 in 100 (10%)10100004 - There is a moderate risk to me41 in 100 (1%)810006633 in 100 (33%)12330004 - There is a moderate risk to me41 in 100 (1%)81000More than 250 million infections73997775063678Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseNeverOften No, I have notNoYesNoExtremely likely7Extremely likely7an extreme desire for me not to from my familyNeutralSomewhat positivelyProviding information MildN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:026/10/20 11:291001645True6/10/20 11:29I AgreeYesSaw on twitter. Seems logical. We need a vaccine to get the world back on track and this seems to be the fastest way to get there.Immediately Strongly agreeSomewhat disagreeSomewhat disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat agreeBroader economic benefits- open economy, less uncertainty.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayNeither agree nor disagreeTime commitment and isolation seems high. Potential long term health risks unforeseen at this time.Long term health risksIsolation.Feeling of having helped in some way11 in 250 (0.4%)7400A lotA moderate amount1 - There is no risk to me11 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk710 in 100 (10%)10100007 - The risk to me is extremely high775 in 100 (75%)14750001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me1Less than 0.001%00Between 20 million and 50 million infections 5125751005150Fairly likely6Somewhat likely5NoTrueTrueFalseFalseFalseNeverMore than onceYes, I have on occasionYesYesNoExtremely likely7Slightly likely5Extensive travel to test siteExtremely likelySomewhat positivelyRisk statistics specifically for my age and health groupN/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:016/10/20 11:301001698True6/10/20 11:30I AgreeYesYouTube saw it on a news feed and sounded reasonable and very scientific.the needs of one is out weighed by the needs of many
makes sense
get a vaccine to market quicker and have us get on with life
about a month agoStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeSomewhat agreeSomewhat disagreeStrongly agreeSomewhat agreeI own a restaurant and want to get back to normal as much as possibleI feel helpless and this is a way to do something positive,I wanted to be guaranteed access to critical care should I be infected with COVID-19,I am likely to be infected with COVID-19 anywayDisagreethe main risk is death, but also flu like symptoms deathflu like symptomsyou are being constantly observed31 in 100 (1%)81000A moderate amountA moderate amount221 in 100 (1%)81000665 in 100 (5%)950005550 in 100 (50%)1350000221 in 5,000 (0.02%)420221 in 250 (0.4%)7400Between 20 million and 50 million infections 20583264196897Extremely likely7Extremely likely7YesmateagreedTrueTrueFalseFalseFalseNeverOften Yes, I donate annuallyNoYesNoExtremely likely7Extremely likely7locationNeutralFairly positivelynot tell themN/AN/AN/AN/AMildMildMildSevereN/A
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Volunteer6/10/20 11:026/10/20 11:301001667True6/10/20 11:30I AgreeYesOnline on the 1 day sooner article in a newspaperGood idea, thought it needs doing.Fairly quicklyStrongly agreeSomewhat agreeNeither agree nor disagreeStrongly agreeStrongly agreeSomewhat disagreeSomewhat disagreeStrongly disagreeNeither agree nor disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeAge- I’m 48. This whilst risk of death small if vaccine doesn’t work, still there.
Vaccine not working and making matters worse.
AgeVaccine not working Demonstrate effectiveness and shave weeks/ months off stage 3 testing.31 in 250 (0.4%)7400A great dealA great deal221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)51004 - There is a moderate risk to me433 in 100 (33%)12330004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 10,000 (0.01%)310Between 20 million and 50 million infections 20793653029841Neither likely nor unlikely4Neither likely nor unlikely4YesOnline, wife.Good idea- get on with it.TrueTrueFalseFalseTrueNeverNeverYes, I have on occasionNoYesNoFairly likely6Fairly likely6Fairly unlikelySomewhat positivelyNoneN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:116/10/20 11:311001188True6/10/20 11:31I AgreeYesThrough a news article onlineI’d like to help out so it was positive. I am also pretty healthy and very active so i feel I would be a good candidate and if this can help others who may not be as healthy or active I’d like to assist. I thought about it but eventually decided it’s better for someone that is younger and healthier than someone older and not as healthy. Strongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly disagreeNeither agree nor disagreeStrongly agreeNot necessarily, more than anything else I really would like to help prevent others from infection and further health complications. I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I am likely to be infected with COVID-19 anywayDisagreeIt might be a little scary but I’d rather it be a controlled environment. The chances of me getting it regardless are probably as high as anyone else’s so if it’s likely to happen then it may as well be monitored and controlled. There are also possibly long term effects that we don’t know about and that is unnerving. Long term impactsThe actual infectionThe fact that it is a controlled exposure vs. uncontrolled environmental exposure.81 in 5,000 (0.02%)420None at allNone at all221 in 50,000 (0.002%)224 - I would accept a moderately greater level of risk41 in 10,000 (0.01%)310551 in 10,000 (0.01%)310331 in 5,000 (0.02%)420221 in 50,000 (0.002%)22Between 5 million and 20 million infections 23256475656027Fairly likely6Fairly likely6I'd prefer not to sayTrueTrueTrueFalseFalseNeverOnceYes, I have on occasionNoNoNoExtremely likely7Extremely likely7Nothing i can think of at this timeExtremely unlikelyNeutralN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:066/10/20 11:311001500True6/10/20 11:31I AgreeYesToday Explained Podcast EpisodeEagerness to participate Immediately. Enrolled right away after listening to the podcast.Strongly agreeSomewhat agreeSomewhat disagreeStrongly disagreeNeither agree nor disagreeSomewhat disagreeStrongly disagreeSomewhat disagreeSomewhat disagreeI am young and as healthy as someone my age could be, so if not me, who? I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreePotential for death from COVID, for getting very sick from COVID, for experiencing long term consequences of having the disease (lung, respiratory, heart issues). Or risks of getting sick and having consequences from the vaccine. Also the burden of being isolated away from my loved ones and partner for weeks. Death, Long term health consequences. Getting sick without death. Altruism and having done something to help in this time. 41 in 100 (1%)81000A lotA lot221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk45 in 100 (5%)950004 - There is a moderate risk to me433 in 100 (33%)12330001 - There is no risk to me11 in 100,000 (0.001%)11221 in 1,000 (0.1%)5100More than 250 million infections60057756039153Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseNeverOften Yes, I donate annuallyNoYesNoFairly likely6Slightly likely5Opposition from my parents and partner, fearSomewhat unlikelySomewhat positivelyRecognition that it is for a good cause. Information. Education on my risk as a healthy 20 something. N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:096/10/20 11:311001287True6/10/20 11:31I AgreeYesOn reddit, in the COVID-19 subredditI knew beforehand of the low risk that young adults face when infected with COVID-19, so I thought it would be a good action if I could help the people who are more vulnerableImmediatelyStrongly agreeSomewhat agreeSomewhat agreeSomewhat agreeStrongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeSomewhat disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I was curious about COVID-19Somewhat agreeBeing away from family and friends, cause you're going to have to be in an isolated facility for the duration of the study. Also, there's a minimal risk of developing serious symptoms due to the infection.Being away from family and friends.The risk of serious illness.Were I to develop serious symptoms, I'd have access to good medical care11 in 10,000 (0.01%)310A lotA lot1 - There is no risk to me11 in 100,000 (0.001%)114 - I would accept a moderately greater level of risk41 in 10,000 (0.01%)3104 - There is a moderate risk to me420 in 100 (20%)11200001 - There is no risk to me11 in 10,000 (0.01%)3101 - There is no risk to me1Less than 0.001%00Between 100 million and 250 million infections8516672730617Fairly likely6Extremely likely7NoTrueTrueFalseFalseFalseNeverNeverYes, I have on occasionNoYesNoFairly likely6Extremely likely7If the isolated facility is more than 100km from my hometownFairly unlikelyFairly positivelyDetails about the study and its risksN/AN/AN/AN/AMildN/AN/AMildN/A
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Volunteer6/10/20 11:046/10/20 11:311001630True6/10/20 11:31I AgreeYesI heard about it through a piece on NPR.I wanted to participate so that we can find a vaccine.Immediately upon hearing about it. I was hoping that I would be able to participate in something that would help bring about a vaccine.Strongly agreeNeither agree nor disagreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat disagreeNeither agree nor disagreeMy children are adults, I have a home based business and can work from anywhere. I'm in a good position to volunteer as it will cause as minimal disruption to my life compared to most others.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreeThe main burden is I may become severely ill with Covid-19 which could potentially lead to my death or long term health conditions. I may have difficulty working during the testing period. I have type A blood, so I realize that I may be more vulnerable to the virus.I worry about how my family will feel in the event of my death, but they understand why I want to volunteer.My ability to work during the testing period.The creation of a large scale vaccine program so that the vulnerable in our population will be protected.55 in 100 (5%)95000A lotA lot4 - There is a moderate risk to me41 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk410 in 100 (10%)10100003320 in 100 (20%)11200004 - There is a moderate risk to me41 in 100 (1%)81000331 in 100 (1%)81000Between 50 million and 100 million infections520669131260Extremely likely7Extremely likely7YesMy husbandHe wanted to participate also, but we decided that it was better for only one of us to participate.TrueTrueFalseFalseFalseMore than onceOne was a psychological study when I was in college, one was a medical study in the past 5 years.Somewhat positiveThere would be risk to my health in this study.More than onceYes, I have on occasionYesYesNoFairly likely6Fairly likely6If I were ill at the time, if someone in my family was ill or if it meant that I would not be available when my daughter has her baby.Somewhat likelySomewhat negativelyThe medical care I will receive, the actual risks of infection, severe complications and death.N/AN/AN/AN/AN/AFatalN/AN/AN/A
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Volunteer6/10/20 11:096/10/20 11:311001341True6/10/20 11:31I AgreeYesI saw it on the internet in a news article.I thought it was a great idea to help our society deal with the virus.I wanted to enroll immediately, time is precious.Strongly agreeSomewhat agreeSomewhat agreeSomewhat agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeThe longer we wait, the more people die and our economy suffers.I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineDisagreeIt depends on where the study is located. How long will have to be quarantined for?I suppose the potential to be severely ill or possibility of death.Having side effects from the vaccine.To quickly get a vaccine out to the public.31 in 100,000 (0.001%)11A great dealA great deal221 in 10,000 (0.01%)310331 in 50,000 (0.002%)22221 in 10,000 (0.01%)3104 - There is a moderate risk to me41 in 1,000 (0.1%)510022Less than 0.001%00More than 250 million infections40520991245223Somewhat likely5Fairly likely6YesI spoke to my boss.We work in an immunology lab. She thought it was an interesting idea but has ethical issues about such a study.TrueTrueFalseFalseTrueNeverMore than onceNo, I have notNoYesNoFairly likely6Fairly likely6I see no reason not to participate if selected.Somewhat unlikelySomewhat positivelyI think to be as transparent as possible about the study and any health issues that could arise.N/AN/AN/AN/AMildN/AN/AN/AFatal
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Volunteer6/10/20 11:066/10/20 11:321001524True6/10/20 11:32I AgreeYesCNN.
I heard about this on the news station CNN. Just trying to get the character count up so I can move on with the survey.		I want to make sure my daughter lives in world where a Vaccine against this infection exists ASAP.The day I heard about it.Strongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeAs a Pastor I believe that the world will one day be free of illness under the reign of God. As a Christian I know it is my duty to begin cultivating that reality in the present moment.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeI am hoping my employer sees the benefits for both our Church and the world. While I'd be out of work for a couple of months, it would be demonstration that the Church cares about the health of it's neighbor's.I would need to know my life insurance would still cover my family if I died as result of this will-full risk. I also am aware of the potential for permanent lung damage.Dying.A vaccine sooner.533 in 100 (33.3%)1233000A great dealA great deal331 in 100 (1%)810004 - I would accept a moderately greater level of risk430 in 100 (33.3%)1233000221 in 100 (1%)810001 - There is no risk to me11 in 1,000 (0.1%)5100221 in 5,000 (0.02%)420Between 5 million and 20 million infections 82087184715162Fairly likely6Somewhat likely5I'd prefer not to sayTrueTrueTrueFalseFalseNeverNeverYes, I have on occasionUnsure/I don’t knowYesNoFairly likely6Fairly likely6My life insurance wouldn't give money to my family as a result of my death. My employer would not allow me to take the time off. I.e. I have to choose between employment and this trial.NeutralFairly negativelyI think a brochure or explanation. Or something to incentivize or encourage employers to keep their folks on even if they have to go away for a time.N/AN/AN/AN/AN/AN/AN/AFatalN/A
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Volunteer6/10/20 11:016/10/20 11:321001836True6/10/20 11:32I AgreeYesI think it was a twitter account from the Rationalist crowd, but I'm not sure.Good idea, I hope it gets done and speeds vaccine developmentImmediatelyStrongly agreeStrongly disagreeNeither agree nor disagreeSomewhat agreeStrongly agreeSomewhat disagreeSomewhat agreeStrongly disagreeStrongly disagreeI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineDisagreeRisk of long-term complications, risk of death, need to spend time not working,Risk of long-term complicationsneed to spend time not workingHelp progress of medicine51 in 100 (1%)81000A great dealA great deal221 in 1,000 (0.1%)51007 - I would accept a seriously greater level of risk75 in 100 (5%)950003310 in 100 (10%)1010000221 in 1,000 (0.1%)5100221 in 1,000 (0.1%)5100Between 100 million and 250 million infections1456853922210Fairly likely6Fairly likely6NoTrueTrueFalseFalseTrueMore than onceSeveral psychological experiments, including PET/MRI/...Somewhat positiveI would be infected with a diseaseMore than onceYes, I donate annuallyYesYesNoFairly likely6Fairly likely6Fairly likelySomewhat positivelyProvide me with information about the study, be prestigious (?)N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:076/10/20 11:321001475True6/10/20 11:32I AgreeYesNewspaper article that talked about the trials and had a link.Extremely excited about the idea of developing a vaccine.Made the decision immediately Strongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeSomewhat agreeSomewhat disagreeStrongly disagreeNeither agree nor disagreeNeither agree nor disagreeI work in health careI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to be guaranteed access to critical care should I be infected with COVID-19Strongly disagreeTime restraints because of work schedule.Time availability NaHelping others, speedy vaccine.61 in 500 (0.2%)6200A moderate amountA lot331 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 100 (1%)810004 - There is a moderate risk to me410 in 100 (10%)1010000331 in 100 (1%)81000331 in 100 (1%)81000Between 5 million and 20 million infections 5033042496355Fairly likely6Extremely likely7NoTrueFalseFalseFalseFalseOnceIt was a medication trial about ten yeara ago.PositiveThe other one was a 2 week in house trial of a prescription NeverYes, I have on occasionNoNoNoFairly likely6Fairly likely6Having to take unpaid time off work.Somewhat likelyFairly positivelyFactual, peer reviewed scientific information N/AN/AN/AN/AN/AN/AN/ASevereN/A
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Volunteer6/10/20 11:046/10/20 11:321001688True6/10/20 11:32I AgreeYesNews article online? Dont remember specificallyVery positive it seemed self evident that exposing people to covid wiuld be the fastest route to effective treatmentImmediatelyStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeThe unknown of a new pathogen.... while i am generally very healthy and believe i am at low risk for the more serious form of the illness, that is impossible to predict with certainty, so some personal risk is inherent Really nothing seriously concerns meSee above... i am not concerned although i understand there is inherent riskFaster results... waiting for “chance” infection means it is difficult to gather enough data31 in 1,000 (0.1%)5100A lotA lot221 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)5100221 in 1,000 (0.1%)51001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me11 in 50,000 (0.002%)22Between 20 million and 50 million infections 14791291011317Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseNeverVery OftenYes, I have on occasionNoYesNoExtremely likely7Extremely likely7Should i develop a serious respiratory or cardiac condition between now and thenFairly unlikelySomewhat positivelyN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:036/10/20 11:321001746True6/10/20 11:32I AgreeYesInternet advertisement about the studyA little scary, but I want to help others and this seemed like the best way to do so.After a day of thinking it overStrongly agreeSomewhat agreeSomewhat disagreeSomewhat disagreeStrongly agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeSomewhat disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeSince it is a novel virus, we cannot be sure how my immune system will respond. Although I am a relatively healthy 39-year-old female, I have read reports of healthy individuals not faring well with Covid-19. Being away for the trial would also be a bit of a burden. not faring wellBeing away from homeHelping the scientific community better understand Covid-19 in order to best help others.61 in 500 (0.2%)6200A lotA great deal4 - There is a moderate risk to me41 in 50,000 (0.002%)225510 in 100 (10%)10100005533 in 100 (33%)1233000221 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 5 million and 20 million infections 38250847797057Fairly likely6Fairly likely6Yesfamilymixed responsesTrueTrueFalseFalseTrueMore than onceTo understand the brain activity of those with anxiety compared with a control groupSomewhat positiveBeing away from my home for a period of time.More than onceYes, I donate annuallyUnsure/I don’t knowYesNoFairly likely6Fairly likely6If any of my loved ones needed my help at home.Somewhat unlikelySomewhat positivelyProving me with the information about the study to share with others.N/AN/AN/AN/AN/AN/AN/AN/AFatal
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Volunteer6/10/20 11:096/10/20 11:331001465True6/10/20 11:33I AgreeYesEmail I think through seeing something in Fitbit.Intrigued by the possibility of helping find a vaccine.Immediately Strongly agreeSomewhat agreeSomewhat agreeNeither agree nor disagreeStrongly agreeStrongly agreeSomewhat disagreeNeither agree nor disagreeSomewhat disagreeI hope this ends up helping everybody I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to find out more about my own healthDisagreePotential infection of my body with Covid 19.Infection is a risk. Minimally asymptomatic, maximally death.Asymptomatic or mild symptoms.To help find a usable vaccine.710 in 100 (10%)1010000A great dealA lot4 - There is a moderate risk to me41 in 100 (1%)81000665 in 100 (5%)95000331 in 1,000 (0.1%)5100221 in 100 (1%)81000221 in 10,000 (0.01%)310Between 50 million and 100 million infections20866741197897Somewhat likely5Somewhat likely5NoTrueFalseFalseFalseFalseNeverMore than onceYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7If it interferes with school or work so much that I need to quit either.Somewhat likelySomewhat negativelyJust by providing as many details as possible about the study.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:016/10/20 11:341001988True6/10/20 11:34I AgreeYesSocial media linking to article on challenge study.Overwhelmingly positive. Within 15 minutes of reading article.Somewhat agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat agreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeI live alone and am in a low risk group (22 years old with no preexisting conditions)I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreePrimary risk of infection from COVID-19 which could result in death or long term consequences (even for a low-risk participant).

Secondary risk that the treatment/ vaccine being used presents unforeseen health complications.		Primary risk of infectionSecondary risk of treatments Allowing the more rapid development of treatment or vaccine.31 in 1,000 (0.1%)5100A lotNone at all221 in 10,000 (0.01%)3107 - I would accept a seriously greater level of risk71 in 1,000 (0.1%)5100331 in 100 (1%)810001 - There is no risk to me11 in 100,000 (0.001%)11221 in 100,000 (0.001%)11Between 20 million and 50 million infections 50802466094Somewhat unlikely3Somewhat unlikely3NoTrueTrueFalseFalseFalseOnceStudying human speech processing Neither positive nor negativeThis would directly involve my health. The previous study simpmy asked me to listen to and interpret audio.More than onceNo, I have notYesYesNoExtremely likely7Extremely likely7If i was forbidden by my employer (an unlikely event)Somewhat likelyFairly positivelyMaterials that contextualize the risks would help with nervous family.N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:026/10/20 11:351001983True6/10/20 11:35I AgreeYesI heard about the thoughts of various studies through news outlets such as CNN.COMI believe that voluntary human studies using willing and informed participants is absolutely vital to timely vaccination creation and production.The instant I heard about it I knew I wanted to join.Strongly agreeSomewhat disagreeStrongly disagreeNeither agree nor disagreeSomewhat agreeStrongly disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeI feel it is important for me to help in any way I can to save lives and end the pandemic.I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeWell, death. I know that there is a chance I could die. I could also have lingering lung damage as well as other lingering health impacts. I understand and am willing to risk it.
A burden could be the isolation in a research facility, but that is a small sacrifice for the potential good.		I worry that I could have long-term health impacts as a result of the effects of the virus.The isolation would be great for me, to be honest. It would give me time to catch up on some reading.Being a data point in a study that could help create a vaccine and increase general medical knowledge.75 in 100 (5%)95000A great dealA great deal4 - There is a moderate risk to me41 in 100 (1%)810007 - I would accept a seriously greater level of risk730 in 100 (33.3%)12330004 - There is a moderate risk to me450 in 100 (50%)1350000221 in 100 (1%)81000221 in 100 (1%)81000Between 20 million and 50 million infections 27043532180848Extremely likely7Extremely likely7NoTrueTrueTrueFalseFalseNeverMore than onceYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7If I had to suffer severe financial hardship like losing my house, I would have to decline.Somewhat likelySomewhat positivelyI would provide them information on the study and assure them that I am informed and willing.N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:026/10/20 11:351001989True6/10/20 11:35I AgreeYesI saw a news article online.I was intrigued at the idea of being able to contribute to medical science and society.pretty much immediatelyStrongly agreeSomewhat disagreeSomewhat agreeSomewhat agreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat disagreenoI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineDisagreerisk of getting covid and dying, risk of having an adverse reaction to the vaccineadverse vaccine reactiondying of covidcontribution to society51 in 1,000 (0.1%)5100A moderate amountA moderate amount221 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 100 (1%)81000331 in 10,000 (0.01%)310221 in 100,000 (0.001%)1122Less than 0.001%00Between 2 million and 5 million infections31044014158049Somewhat likely5Somewhat likely5NoTrueFalseTrueFalseFalseNeverVery OftenYes, I have on occasionYesYesNoExtremely likely7Extremely likely7if I have already contracted the virus or if I become sick for some other reason.Somewhat likelySomewhat positivelyInformation might help but no one could influence me not to.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:186/10/20 11:361001038True6/10/20 11:36I AgreeYesI read a few news articles.As a young, healthy adult with no pre-existing conditions, reaction was positive.immediatelyStrongly agreeSomewhat agreeNeither agree nor disagreeStrongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayAgreeTime. Obviously there are risks of side effects from vaccine and getting sick with Covid.That the trial would take a lot of time. Covid. As a young healthy adult with no pre-existing conditions, the risk seems tolerable.Get the world back to normal as soon as possible.31 in 5,000 (0.02%)420A great dealA great deal221 in 50,000 (0.002%)224 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)51004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 10,000 (0.01%)310221 in 50,000 (0.002%)22Between 50 million and 100 million infections150140610000000Somewhat likely5Somewhat likely5NoTrueTrueTrueFalseFalseNeverOften Yes, I donate annuallyNoYesNoSlightly likely5Neither likely nor unlikely4Isolation from family. The less time the better.NeutralFairly positivelyAn accurate assessment of risk based on current data.N/AN/AN/AN/AN/AMildN/AMildMild
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Volunteer6/10/20 11:076/10/20 11:361001706True6/10/20 11:36I AgreeYesI learned about it via redditI think it makes the most moral and economic sense. The reality is that vaccine development, despite what is heralded in the press, will take a long time, and even longer still if we try to test with naturally occurring infection at a time when we are actively trying to *reduce* the number of infections. I have virtually no risk factors, as a young, healthy, and active female; ergo, it makes sense to me that I could put myself at a low risk in order to better society.Relatively quickly.Strongly agreeSomewhat agreeStrongly agreeSomewhat agreeStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeNo; my primary considerations are getting society moving forward with as little damage as possible.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeThere are no guarantees. Technically, I am not very likely to get seriously ill, given my age and general health. However, that isn't a sure thing.

Moreover, since we've been racing through clinical trials, we don't have a good sense of the long-term impact of any treatment we supply to those who get sick.		Getting seriously ill and dying, as unlikely as that might be.Long-term effectsHelping society move faster past this31 in 500 (0.2%)6200A moderate amountA moderate amount221 in 1,000 (0.1%)5100555 in 100 (5%)950003310 in 100 (10%)1010000221 in 10,000 (0.01%)3101 - There is no risk to me11 in 1,000 (0.1%)5100Between 20 million and 50 million infections 3024013754314Somewhat likely5Somewhat likely5YesI discussed with my parents, one of whom works in pharmaceuticals.They were neither supportive nor disapproving.TrueTrueTrueFalseFalseNeverMore than onceYes, I have on occasionNoYesNoExtremely likely7Extremely likely7If the burden was unreasonable (e.g., having to go to a facility for 4 months or something)NeutralNeutralI suppose information about the precautions taken and study design would be helpful.N/AN/AN/AN/AN/ASevereN/AN/AN/A
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Volunteer6/10/20 11:036/10/20 11:361001994True6/10/20 11:36I AgreeYesI read about this in a news articleI would like to help and contribute to societyImmediatelyStrongly agreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I was curious about COVID-19Somewhat agreeIt is possible that a vaccine could cause side effects having a bigger impact on my life than COVID 19 potentially would. Being exposed to covid 19 could, of course, cause health problems.Unwanted side effects/unintended consequencesHealth problems caused.by exposure to covid 19Feeling as though Im contributing to the greater good71 in 50,000 (0.002%)22A lotA lot221 in 100,000 (0.001%)116620 in 100 (20%)11200005550 in 100 (50%)1350000221 in 10,000 (0.01%)31022Less than 0.001%00Between 100 million and 250 million infections53019682435372Somewhat likely5Fairly likely6NoTrueFalseTrueTrueFalseNeverOften Yes, I donate annuallyNoYesNoFairly likely6Fairly likely6Details emerge that Im currently not aware ofExtremely likelyNeutralThis is not a concern to me. N/AN/AN/AN/AMildMildN/AN/AN/A
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Volunteer6/10/20 11:106/10/20 11:371001595True6/10/20 11:37I AgreeYesI saw it reported on CNN and there was a link to sign up. That it is a good idea and anyone who is low risk should think seriously about volunteering. Almost immediately after reading about itStrongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat agreeStrongly agreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywaySomewhat agreeThe isolation and figuring out how to take several weeks away from work.Being away from home for an extended period of time. Making it work with my job.Being closely monitored and able to receive medical attention right away41 in 100 (1%)81000A littleA lot221 in 100 (1%)81000555 in 100 (5%)950005533 in 100 (33%)12330002210 in 100 (10%)1010000221 in 100 (1%)81000Between 50 million and 100 million infections50100002024911Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseMore than oncePsychology studies at college that we were required to complete for credit. Neither positive nor negativeMuch more intense and longer lasting. OnceYes, I have on occasionNoYesNoFairly likely6Fairly likely6If it lasted for several months rather than several weeks. Fairly likelyFairly positivelyMy family isn't upset at the idea, but information on mitigation efforts and access to health care if things go wrong will make people feel better about their loved ones participating. N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:096/10/20 11:371001659True6/10/20 11:37I AgreeYesI saw this in the news, I believe.At first I was a bit unsure about volunteering to test possible vaccines, but my health is good and figured the risk outweighed the potential benefits to society at large.I thought about it for several days.Strongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeStrongly disagreeSomewhat disagreeStrongly disagreeMy age and where I am in my life. I've raised my kids, and retired but have a satisfying life. It would be nice to give back.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeI suppose it could end up killing me, but I'm confident that since I'm quite healthy I'd be okay (assuming reasonable medical care).I'm not really looking forward to dying - I guess if I became a burden to others that would be worse.Could I get reasonable medical care if I find myself infected.It would contribute to the availability of a vaccine for the population.520 in 100 (20%)1120000None at allA lot4 - There is a moderate risk to me420 in 100 (20%)11200004 - I would accept a moderately greater level of risk430 in 100 (33.3%)1233000221 in 100 (1%)810005520 in 100 (20%)1120000221 in 100 (1%)81000Between 20 million and 50 million infections 30385045032277Extremely likely7Extremely likely7NoTrueFalseFalseFalseFalseNeverOften Yes, I donate annuallyNoYesNoFairly likely6Fairly likely6If the risks identified to me were higher than I had thought they would be.NeutralNeutralAny information about the study made available ahead of time would be great. (all pros and cons).N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:096/10/20 11:371001666True6/10/20 11:37I AgreeYesI was googling current vaccine trials in progress for covid our of curiosity when I came across this website. It’s a very good idea and neededImmediatelyStrongly agreeNeither agree nor disagreeSomewhat disagreeNeither agree nor disagreeStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeMy friends friend died at age 32 of covid, it was devastating, I want to be part of the cure and / or vaccination for this disease. I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeBecoming infected, and needing extreme medical intervention.Needing extreme medical intervention Becoming infected Providing research that can be studied, helping understand a novel disease, and possibly being part of the cure / vaccination. 220 in 100 (20%)1120000A littleA lot221 in 100 (1%)81000661 in 100 (1%)810003310 in 100 (10%)10100003320 in 100 (20%)1120000221 in 100 (1%)81000Between 100 million and 250 million infections27658206673333Extremely likely7Extremely likely7NoTrueFalseTrueFalseFalseNeverMore than onceYes, I have on occasionYesYesNoExtremely likely7Extremely likely7Nothing at this time NeutralSomewhat positivelyProvide detailed information and potential results N/AN/AN/AN/AMildMildN/AMildN/A
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Volunteer6/10/20 11:136/10/20 11:381001463True6/10/20 11:38I AgreeYesI believe I heard about it on an interview with National Public Radio. However, I was interested in participating in a Covid-19 vaccine study with Kaiser back in March.I lost two friends to covid-19 and I have loved ones who I am concerned about with this disease. I suppose I felt helpless being stuck in my house and felt like I want to make a difference. The decision was immediate for me. I want to help the research progress.Strongly agreeStrongly agreeSomewhat agreeStrongly agreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly agreeNeither agree nor disagreeI am a healthy woman in her later 30s so I felt like I would hopefully be at a lower risk.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeI realize that there is the risk of getting COVID-19 and having complications from the disease. We do not know much and there is the possibility of death or serious future health impacts.

Having to spend time undergoing the study.

Having to get a vaccine that does not work.

I am concerned about dying or future health impacts.Having to spend time undergoing the study.Finding a vaccine that works and that can save lives.633 in 100 (33.3%)1233000A littleA lot221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk410 in 100 (10%)10100006650 in 100 (50%)1350000221 in 5,000 (0.02%)420221 in 1,000 (0.1%)5100More than 250 million infections81064749810648Fairly likely6Fairly likely6NoTrueFalseTrueFalseFalseNeverNeverYes, I donate annuallyYesYesNoExtremely likely7Extremely likely7I don't think there would be much to dissuade me. I suppose there could be something I wouldn't anticipate like if my child did not want me to participate or my spouse.Somewhat likelyNeutralI think list the precautions that the study would take and maybe some guaranteed medical care?N/AN/AN/AN/AN/AN/AN/AFatalN/A
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Volunteer6/10/20 11:026/10/20 11:381002131True6/10/20 11:38I AgreeYesFacebook, I think either an advertisement or video or somethingSounded like a way to help out people since I feel like I'd have less of a chance of dying than most demographicsImmediately within 1 hour of hearing about itStrongly agreeSomewhat disagreeSomewhat agreeSomewhat agreeSomewhat agreeSomewhat agreeSomewhat agreeSomewhat agreeStrongly disagreeI can work from home as a software engineer so I'd be less impacted than most peopleI want to help others and potentially save lives,I wanted to receive financial reimbursement for participating,I wanted to be guaranteed access to critical care should I be infected with COVID-19AgreeDying
Complications/extended confinement
Not being able to go outside, socialize, visit stores/shop, have the type of food I want available, less privacy		Death, extended confinement/less privacyNot being able to go outsideHelping people41 in 1,000 (0.1%)5100A great dealA great deal221 in 10,000 (0.01%)310551 in 100 (1%)810002210 in 100 (10%)1010000331 in 10,000 (0.01%)31022Less than 0.001%00Between 100 million and 250 million infections60570091022455Somewhat likely5Somewhat likely5YesParentsBad ideaTrueTrueFalseTrueFalseMore than onceAnxiety disorder studySomewhat positiveInfected with a disease instead of just studying my pre existing conditionNeverNo, I have notYesYesNoSlightly unlikely3Slightly unlikely3Significant burden to my everday lifeSomewhat unlikelySomewhat negativelyShort image highlighting why it isn't too risky and the chance of dying is lowN/AN/AN/AN/AN/AMildN/AMildN/A
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Volunteer6/10/20 11:076/10/20 11:381001858True6/10/20 11:38I AgreeYesKept waiting and searching the internet for one to volunteer inIf we can help save lives sooner than later, let’s do it ImmediatelyStrongly agreeStrongly disagreeNeither agree nor disagreeSomewhat agreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat disagreeI don’t have children, so if more people like me helped, it can save lives sooner and not take away a parent from their childI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreeRisk of death first and foremost, then potentially becoming ill.Death, but I’m not “concerned” with itBecoming illSaving lives sooner and children not losing parents or vice versa51 in 100 (1%)81000A great dealA great deal1 - There is no risk to me11 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk75 in 100 (5%)95000221 in 50,000 (0.002%)221 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me11 in 100,000 (0.001%)11Between 2 million and 5 million infections353148120000Fairly likely6Fairly likely6YesMom, best friendConcerned, but very supportiveTrueTrueFalseFalseFalseNeverOften Yes, I donate annuallyNoYesNoExtremely likely7Extremely likely7If doctors and researchers weren’t confident in the studySomewhat likelyFairly positivelyNot only could this save millions of lives, but if the worse happened to me, it was trying to save others and being I don’t have kids, I would rather I participate than parents who could be potentially taken from their childrenN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:066/10/20 11:391001959True6/10/20 11:39I AgreeYesIt was a news24 article about the possibility of human trails to generate a vaccine.I thought I need to be part of this to potentially help other people.I made it immediately Strongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat agreeThere might be negative impacts from the vaccine on my body. The isolation could have an affect on my mental well being. The monitoring of such a study might be an intrusive experience.The intrusive nature of a study. I am a private person.The impact of isolation on my mental well being.Main benefit is to be part of something bigger than my own person health.51 in 100,000 (0.001%)11A moderate amountA great deal1 - There is no risk to me11 in 50,000 (0.002%)22331 in 10,000 (0.01%)3104 - There is a moderate risk to me410 in 100 (10%)10100004 - There is a moderate risk to me41 in 10,000 (0.01%)3101 - There is no risk to me11 in 100,000 (0.001%)11Between 5 million and 20 million infections 36116221992448Somewhat likely5Fairly likely6NoTrueTrueFalseFalseTrueNeverVery OftenYes, I donate annuallyYesUnsure/I don’t knowNoFairly likely6Fairly likely6My family begs me not tooExtremely likelyFairly negativelyInformation regarding the study would helpN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:026/10/20 11:391002198True6/10/20 11:39I AgreeYesI can't remember exactly how I heard about it, but I know I read about it online.I remember thinking it sounded difficult but important.I knew pretty much right away. Somewhat agreeSomewhat disagreeNeither agree nor disagreeStrongly disagreeStrongly agreeNeither agree nor disagreeSomewhat disagreeStrongly disagreeSomewhat disagreeI am young, healthy, and female, and I know that those are factors that might make me less likely to die or become seriously ill of COVID-19, so I thought that if people are needed to participate in studies, people like me should offer to do so.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreeHaving to be away from work and family and be isolated for the study, the risk of serious illness or problems with the vaccineProbably taking time away from workRisk of problems with the vaccine itself/vaccine reactionsHelping to speed the development of a vaccine, possibly getting vaccinated against it (if the vaccine turns out to be safe and effective)75 in 100 (5%)95000A littleA little221 in 1,000 (0.1%)51006610 in 100 (10%)10100003310 in 100 (10%)1010000221 in 1,000 (0.1%)5100221 in 250 (0.4%)7400Between 20 million and 50 million infections 21895651399621Neither likely nor unlikely4Neither likely nor unlikely4NoTrueTrueTrueFalseFalseOnceIt dealt with risk factors for gambling addiction. I was chosen at random from my class to participate when I was in college.Neither positive nor negativeThere was no risk to me in the previous study I participated in.More than onceNo, I have notYesYesNoFairly likely6Fairly likely6It could be hard for me to leave work. I can't lose my job for it. Fairly likelyNeutralI think more information on the study could be helpful, but I can't think of anything that I believe would significantly reduce their upset. N/AN/AN/AMildN/AN/AN/ASevereN/A
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Volunteer6/10/20 11:206/10/20 11:391001116True6/10/20 11:39I AgreeYesvia a news story on CNN.comsounded like a worthwhile causeimmediatelyStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat disagreeSomewhat agreeSomewhat disagreeNeither agree nor disagreeSomewhat disagreeStrongly disagreenoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayDisagreehow my body's immunity will reactnonenoneto help others41 in 500 (0.2%)6200A lotA lot221 in 100,000 (0.001%)11551 in 10,000 (0.01%)3105533 in 100 (33%)1233000221 in 100,000 (0.001%)11221 in 100,000 (0.001%)11Between 20 million and 50 million infections 62018088195580Fairly likely6Fairly likely6NoTrueFalseTrueFalseFalseNeverMore than onceYes, I have on occasionYesYesNoExtremely likely7Extremely likely7financial damage to meNeutralSomewhat positivelyfocus on the benefit to societyN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:116/10/20 11:391001672True6/10/20 11:39I AgreeYesOn a podcast, specifically the WeedsIt is an ethical necessity to perform such a study, provided that reasonable safeguards can be put in placeI immediately knew that I wanted to. Then I took time to reflect and discuss with family before arriving on a final decision.Strongly agreeSomewhat disagreeSomewhat agreeStrongly disagreeStrongly agreeSomewhat agreeSomewhat disagreeStrongly agreeSomewhat disagreeA strong sense of patriotism. I have never served in the military or a public service sector. I see this as an opportunity to serve my country and world. I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to be guaranteed access to critical care should I be infected with COVID-19Strongly disagreeRisk of short term illness, longer term/chronic lung damage, or deathDeath, long-term harmShort term illnessSaving lives directly via reducing COVID deaths while also reducing deaths of despair by opening society sooner.75 in 100 (5%)95000A great dealA great deal221 in 1,000 (0.1%)5100661 in 100 (1%)810004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 10,000 (0.01%)310221 in 50,000 (0.002%)22Between 50 million and 100 million infections236569410000000Fairly likely6Extremely likely7YesPartner, sibling, parentsThey were apprehensive but supportiveTrueTrueFalseFalseFalseOften Psychology and cognitionPositiveThere would be risk to my safetyMore than onceYes, I donate annuallyNoYesNoExtremely likely7Slightly unlikely3If the vaccine had not already been successful in phase ii trialsFairly likelyFairly positivelyProvide information about the medical treatment that will be received by participants that become illN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:116/10/20 11:401001715True6/10/20 11:40I AgreeYesonline article connected to the petitionprovocative but may be needed future approach to more quickly combat pandemic infectionsI am a cell & molecular biologist by training - I understand the need and risks associated with such a study. And my own risk profile.Strongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeSupport advancing science and population healthI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreemedical risks - however given my demographics and lifestyle, I am low-risk based on current evidence
one concern would be the persistence of the symptoms as there seems to be some duration in certain individuals
Unknown long-term risks (ie manifestation and/or increased risk at older age)		longterm potential risk from infection as part of natural disease pathologyacute medical risks of the infection (early infection phase)constant monitoring in case of AE and dramatic change in health41 in 1,000 (0.1%)5100A great dealA great deal1 - There is no risk to me11 in 10,000 (0.01%)310551 in 100 (1%)810004 - There is a moderate risk to me41 in 100 (1%)810001 - There is no risk to me11 in 5,000 (0.02%)4201 - There is no risk to me11 in 10,000 (0.01%)310Between 5 million and 20 million infections 19469424130067Somewhat likely5Somewhat likely5YespartnerconcernedTrueTrueFalseFalseFalseNeverOften Yes, I donate annuallyYesYesNoFairly likely6Slightly likely5access to dedicated study-related medical care supervision and supportSomewhat likelySomewhat negativelyFamily - concernsN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:086/10/20 11:401001965True6/10/20 11:40I AgreeYesI saw it online somewhere, but I don't remember the details any more.I like the idea of any study.I decided immediately that it would be interesting.Strongly disagreeStrongly disagreeSomewhat disagreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly agreeStrongly disagreeSomewhat disagreeNoI wanted to be part of a clinical trial,I wanted to contribute to the progress of medicine,I wanted to receive financial reimbursement for participatingSomewhat agreeThe main risk is developing a severe case of viral infection, and the main burden is having to be isolated for a period of time during the study.The confinement for two weeks in a facility is more concerning to me than the possibility of falling ill.I really am not concerned at all about contracting COVID-19.I have nothing better to do with my time as a person who is not currently employed, and there will be a financial compensation of some sort, however small.21 in 1,000 (0.1%)5100A great dealA great deal3310 in 100 (10%)10100004 - I would accept a moderately greater level of risk430 in 100 (33.3%)1233000221 in 1,000 (0.1%)5100221 in 100,000 (0.001%)1122Less than 0.001%00Between 2 million and 5 million infections10012741413855Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseNeverMore than onceNo, I have notNoNoNoNeither likely nor unlikely4Neither likely nor unlikely4I don't want to participate if there is no monetary compensation.Somewhat likelySomewhat negativelyI don't think you could do anything to change the opinion of others, and you shouldn't need to. I am an adult and don't need anyone's approval or permission.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:126/10/20 11:411001744True6/10/20 11:41I AgreeYesI found it linked from a Reddit postI've always wondered why it was so hard for people to be able to do human trials on people who are willing to help. I'm willing to help.Thought about it for a short minuteStrongly agreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeStrongly agreeSomewhat disagreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeNoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayDisagreeThe unknown would definitely be the worst thing. Whether it will work, if it won't, will it end up being worse? Thoughts like that would be frustrating, but regardless of the outcome, it's information that can be used. Being confined for a long period of time, plus there's the possibility of getting really sick from the virus.The unknownBeing confined for a long period.Gathered information to help the general public.31 in 100 (1%)81000A littleA lot221 in 1,000 (0.1%)51005530 in 100 (33.3%)12330004 - There is a moderate risk to me41 in 100 (1%)810003320 in 100 (20%)1120000221 in 10,000 (0.01%)310Between 20 million and 50 million infections 15014063328103Fairly likely6Fairly likely6NoTrueTrueFalseTrueFalseNeverMore than onceNo, I have notUnsure/I don’t knowYesNoFairly likely6Extremely likely7School, but that's unlikely to cause problems.Somewhat likelyFairly negativelyInformation about what's going on and why. I feel most people would accept risk for the greater good.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:156/10/20 11:411001540True6/10/20 11:41I AgreeYesI did an internet search to see how I could help.I’m willing to do anything to end this as soon as possible.A decision I made immediately.Strongly agreeSomewhat agreeStrongly disagreeSomewhat agreeSomewhat agreeSomewhat disagreeSomewhat agreeSomewhat disagreeNeither agree nor disagreeIt has ruined the economy. Kids need to be back in school. I want to help get us back to normal.I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to receive financial reimbursement for participatingAgreeSeclusion and boredom. BoredomDyingHelping get the world back to normal.11 in 100,000 (0.001%)11A great dealA great deal1 - There is no risk to me11 in 100,000 (0.001%)11551 in 10,000 (0.01%)310551 in 1,000 (0.1%)51001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me1Less than 0.001%00Between 20 million and 50 million infections 20218883111150Neither likely nor unlikely4Somewhat unlikely3YesFamily and friendsIndifferentTrueTrueFalseTrueFalseNeverNeverNo, I have notNoYesNoFairly likely6Fairly likely6Fairly likelySomewhat positivelyInformation is always good.N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:066/10/20 11:411002098True6/10/20 11:41I AgreeYesNews article about the concept and some risks involved that was published several weeks ago on CNN.I was surprised that such a study existed.It took some time to think about, after reading further about the potential hazards that come with such a study, I figured that the potential benefits outweigh the costs.Strongly agreeStrongly agreeSomewhat agreeStrongly agreeStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeStrongly agreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat disagreePotential to spread the virus to healthcare workers, the possibility of a worse infection due to the experimental vaccine, and the time needed to complete such a study.Possibility of an exacerbated infection.The time necessary to conduct the study.Potentially speeding up the timeline for a working vaccine.510 in 100 (10%)1010000A littleA moderate amount221 in 100 (1%)810007 - I would accept a seriously greater level of risk720 in 100 (20%)11200003350 in 100 (50%)13500002210 in 100 (10%)1010000225 in 100 (5%)95000Between 50 million and 100 million infections10798231963009Somewhat likely5Fairly likely6NoTrueTrueTrueFalseFalseNeverNeverYes, I have on occasionUnsure/I don’t knowYesNoFairly likely6Extremely likely7Depends on the particulars of the study, such as the effectiveness of the vaccine.Somewhat likelySomewhat negativelyProviding info about the study, ensuring their safety from infection.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:186/10/20 11:421001406True6/10/20 11:42I AgreeYesAtlantic Monthly article spring 2020Great idea! Why the character minimum?ImmediatelyStrongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat agreeNeither agree nor disagreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to be guaranteed access to critical care should I be infected with COVID-19DisagreeRisk of death or permanent disability. Loss of income.Death or disability.Social ostracization.Feeling good about making a contribution.71 in 100 (1%)81000A lotA great deal5520 in 100 (20%)11200005530 in 100 (33.3%)1233000221 in 50,000 (0.002%)225550 in 100 (50%)1350000221 in 100,000 (0.001%)11Between 20 million and 50 million infections 21251563071920Somewhat likely5Somewhat likely5NoTrueTrueFalseTrueTrueNeverVery OftenYes, I donate annuallyNoYesNoFairly likely6Extremely likely7Concern about competence and standardsSomewhat likelySomewhat positivelyGuaranteeing as good care as possible
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Volunteer6/10/20 11:036/10/20 11:421002351True6/10/20 11:42I AgreeYesReading an online articleIntrigued. Curious. Interested. Motivated. Two months ago after reading articles about other volunteersStrongly agreeStrongly disagreeSomewhat agreeStrongly agreeStrongly agreeStrongly disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeI am a trained PhD business researcherI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeComplications with existing conditions (hypertension, high cholesterol) that are currently being treated by my PCP

Contracting severe respiratory difficulties

Ongoing post-exposure conditions (prolonged illness, chronic fatigue, immunological complications, etc)		Chronic fatigue and auto-immune complicationsComplications with existing conditionsIncreased clinical and trial data for scientific research; wider demographic base of research participants85 in 100 (5%)95000A lotA lot4 - There is a moderate risk to me41 in 1,000 (0.1%)5100551 in 100 (1%)810002220 in 100 (20%)11200004 - There is a moderate risk to me41 in 100 (1%)81000221 in 10,000 (0.01%)310Between 20 million and 50 million infections 503640210000000Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseOnceTesting skin moisture changes of the penis head (thereby preventing HIV infection) in adult males after being circumcised PositiveThere was no inherent danger in the circumcision researchOnceYes, I donate annuallyNoYesNoSlightly likely5Fairly likely6Inadequate safeguards preventing me infecting family members and friendsFairly likelySomewhat negativelyProviding study info and probabilities of illness/complicationsN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:176/10/20 11:431001513True6/10/20 11:43I AgreeYesTweets by Matt Yglesias, a reporter at Vox who also signed up for 1 Day SoonerI liked the idea, as that kind of study should hasten the vaccine effortsI made the decision almost immediatelyStrongly agreeStrongly disagreeNeither agree nor disagreeStrongly agreeStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat disagreeNoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreeThe relatively small risk of severe covid-19 complications, as well as the relatively small risk of severe vaccine complicationsCovid-19 complicationsVaccine complicationsAdvancing science and potentially being protected from later infections21 in 100 (1%)81000A great dealA great deal221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk41 in 100 (1%)810004 - There is a moderate risk to me410 in 100 (10%)1010000221 in 100 (1%)810001 - There is no risk to me11 in 100,000 (0.001%)11Between 20 million and 50 million infections 21234581015538Fairly likely6Fairly likely6YesParents and close friendsParents were alarmed, close friends were intriguedTrueTrueFalseFalseFalseMore than onceLinguistics studies using EKGs for assorted thingsPositiveA human challenge study would involve some small risk of deathNeverYes, I have on occasionNoNoNoFairly likely6Extremely likely7My parents properly freaking out might impact my decisionNeutralSomewhat positivelyDetailed information about the level of care I would receive upon developing complications from the diseaseN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:076/10/20 11:431002160True6/10/20 11:43I AgreeYesFox News and through various news articles, and other expert opinions, pros and cons, concerning challenge trials. Great way to assist mankind beat COVID-19 pandemicI made it immediately. I have 3 biology degrees, 20 years biomedical research experience, 10 publications, and 35 years participating in many other human clinical research studiesSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeSomewhat agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreerisks are minimali am not keen on getting sickfinancial renumerationadvance science81 in 100 (1%)81000A moderate amountA little551 in 100 (1%)81000551 in 100 (1%)810004 - There is a moderate risk to me41 in 100 (1%)810004 - There is a moderate risk to me41 in 100 (1%)81000331 in 250 (0.4%)7400Between 20 million and 50 million infections 22559851215547Extremely likely7Extremely likely7Yesmy wifeshe did not commentTrueTrueFalseFalseFalseVery Oftenblood volume studies, vaccine studies, blood products separations studies Extremely positiveit is more dangerous..yet greater reward to expedite the development of COVID-19 treatmentsVery OftenYes, I have on occasionYesYesNoExtremely likely7Extremely likely7if an effective COVID-19 vaccine is already being deployedNeutralSomewhat positivelyproviding statistical risk assessmentSevereFatal
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Volunteer6/10/20 11:026/10/20 11:441002502True6/10/20 11:44I AgreeYesThe idea generally speaking I heard of over a CNN featured article. First hearing about this specific study/work was due to a friend’s posting about it on LinkedIn.I hope it can be done well, ethically, and with vigor to resolve this crisis.I took some time to consider what would be needed and whether I could contribute most effectively to the goals of the study.Strongly agreeSomewhat disagreeSomewhat disagreeNeither agree nor disagreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat disagreeI don’t really know; but I can definitely say that the pain in my local community (Harlem/NYC) is something I can’t stand and want to ensure something can be done to provide some hope to this situation.I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeInfection/reinfection that could lead to lung/organ damage; non-zero chance of death; infection of others; another round of isolation/quarantineInfection of others; non-zero risk of death (in that order)Another round of isolation/quarantineExpanding our knowledge of transmission modes; expanding knowledge of infection behavior; other factors we simply don’t know yet; increasing speed to a vaccine45 in 100 (5%)95000A lotA lot221 in 100 (1%)810006620 in 100 (20%)11200003310 in 100 (10%)10100004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 250 (0.4%)7400Between 5 million and 20 million infections 7559881727493Somewhat likely5Fairly likely6I'd prefer not to sayTrueTrueTrueTrueFalseMore than onceAll of them were social psychology studies or cognitive studies.PositiveInfection of a real virus/disease; potential for personal harm.More than onceYes, I donate annuallyUnsure/I don’t knowYesNoFairly likely6Slightly likely5Personal life burdens; family emergencies; my own personal baseline health levelSomewhat likelySomewhat negativelyI’m really not sure; I assume a lot of information about risk and how risk is mitigated would help. I have a family of worrywortsMildN/AN/AN/AMildN/AN/AN/AFatal
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Volunteer6/10/20 11:026/10/20 11:441002496True6/10/20 11:44I AgreeYesI forget. Maybe the news or maybe Google searchesSeems like a good way to get a vaccine developed soonerI thought about it for a little whileStrongly agreeSomewhat disagreeSomewhat disagreeNeither agree nor disagreeNeither agree nor disagreeSomewhat disagreeStrongly disagreeSomewhat disagreeStrongly disagreeTo help get the world back to normal soonerI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveAgreeDeath or severe illness
Test protocols		DeathTest protocolsSocietal benefits21 in 500 (0.2%)6200A great dealA great deal221 in 10,000 (0.01%)310331 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 100 (1%)81000221 in 50,000 (0.002%)22221 in 100,000 (0.001%)11Between 50 million and 100 million infections21993291310404Extremely likely7Extremely likely7NoTrueTrueFalseFalseFalseOnceNutrition researchNeither positive nor negativePotentially dangerousNeverYes, I donate annuallyNoNoNoFairly likely6Fairly likely6I don't know enough about the details to know what I don't knowSomewhat unlikelyFairly positivelyMomN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:006/10/20 11:441002610True6/10/20 11:44I AgreeYesI started thinking about the idea of a challenge study in March when initial predictions of 1-2 years for a vaccine were promulgated. A friend in the pharma industry helped me think through some of the issues. I then saw an article about 1 Day Sooner and signed upI thought that it would significantly accelerate vaccine development and that would be a great benefit for the world. In times of crisis, firefighters rush into burning buildings to save children and our grandfathers stormed the beaches at Normandy. These are dangerous but necessary. I feel the same about getting a vaccine on an accelerated timetable.Strongly agreeSomewhat agreeStrongly disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeSomewhat disagreeStrongly disagreeStrongly disagreeI do not believe I have a high risk of mortality from the disease.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat disagreeThe primary risk is the high probability of getting sick. My expectation is that the most likely outcome would be to spend 2-3 weeks in misery followed by a month or two of recovery. The next most likely outcome is to either get the placebo virus, have the vaccine work or be relatively asymptomatic. I believe there is well less than a 1% mortality risk.
The second burden would be being isolated and getting poked and prodded by doctors for a few weeks/months. 		getting sickbeing poked and prodded by doctorsNone to me other than knowing I helped many people avoid getting sick or passing away as well as helping the economy recover and allow people to start doing the things they enjoy sooner.41 in 500 (0.2%)6200A moderate amountA moderate amount221 in 1,000 (0.1%)5100551 in 100 (1%)810003310 in 100 (10%)1010000221 in 10,000 (0.01%)310221 in 5,000 (0.02%)420Between 20 million and 50 million infections 16573442013772Fairly likely6Fairly likely6YesWife, a pharma exec and posted on Facebookpeople generally seemed to think this made sense when I explained my reasoning. My wife was less thrilledTrueTrueTrueFalseFalseMore than onceI have filled out surveys like this. never a clinical trialNeither positive nor negativeThis one has a high probability of getting sickMore than onceYes, I donate annuallyUnsure/I don’t knowYesNoExtremely likely7Fairly unlikely2If there is an effective therapeutic, then there is not really a need for a challenge trialSomewhat unlikelySomewhat positivelyAccurately explain the risks for a healthy adult my age w/o co-morbiditiesN/AN/AN/AN/AMildN/AN/ASevereN/A
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Volunteer6/10/20 11:026/10/20 11:441002508True6/10/20 11:44I AgreeYesI was browsing online forums and stumbled across a thread about the study. The person that started the thread is another participant. After researching the study and looking up videos about it, I decided to apply. When I first heard about it, I was very intrigued about the whole process. As a college student working towards a BSN, I think the study can only help make strides in developing a stable vaccine. I took time to way all the options before applying. Strongly agreeStrongly disagreeSomewhat agreeSomewhat disagreeSomewhat agreeSomewhat disagreeStrongly disagreeStrongly disagreeStrongly disagreeThe idea that a study can speed up time for a vaccine to be developed so that fewer people have to endure this infection. I want to help others and potentially save lives,I was curious about COVID-19,I wanted to contribute to the progress of medicineDisagreeSince the study is in a controlled and monitored area, there shouldn’t be many risks, but I understand that there are still risks involved. I believe that the main burden for anyone is being infected and not knowing the outcome. It will then become a day to day situation in which you will have to trust in the healthcare associates. Not knowing the outcome is the only risk or concern for the trial. While it is also my greatest concern, not knowing the outcome is also the least of my concern. I signed up so that an advancement could be made. A controlled infection study will have the benefit of being monitored more closely without interruptions from other sources. 710 in 100 (10%)1010000A great dealA moderate amount4 - There is a moderate risk to me41 in 100 (1%)81000661 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 10,000 (0.01%)310331 in 50,000 (0.002%)22331 in 1,000 (0.1%)5100Between 5 million and 20 million infections 21849741524921Somewhat likely5Neither likely nor unlikely4YesParents They were nervous until I fully explained the study. I have full support as it is my decision. TrueTrueFalseTrueFalseNeverOften Yes, I have on occasionNoYesNoFairly likely6Fairly likely6I do not believe anything would stop be from participating in the study. I understand the risks involved. Somewhat likelyNeutralI think more information is always helpful since this is an unknown trial in terms of what might or might not happen. Information takes away the fear of what might happen. N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:056/10/20 11:441002340True6/10/20 11:44I AgreeYesI think I heard about it on an NPR News episodethat i could potentially helpIt took some time, and i'm still not 100% committed.Strongly agreeSomewhat agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeStrongly agreeStrongly agreeSomewhat agreeDue to my own health (very good!) and the poor health of those that I love drove me to help. if I can help them, it seems worth it.I want to help others and potentially save lives,I wanted to be guaranteed access to critical care should I be infected with COVID-19,I am likely to be infected with COVID-19 anywayStrongly agreeThe biggest risk is that I do not know how my body will respond to COVID. I've heard news reports of very healthy people like myself becoming very sick. That is scary for me.

I also don't know how this will impact my full time job.		dying or becoming permanently impacted by COVID.if i have a milder case, i'm least concerned about my resilience in handling it. immediate health care61 in 500 (0.2%)6200A lotA lot331 in 10,000 (0.01%)310551 in 100 (1%)81000331 in 1,000 (0.1%)5100221 in 10,000 (0.01%)3101 - There is no risk to me11 in 100,000 (0.001%)11Between 20 million and 50 million infections 2000424932330Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseMore than onceI did an Multiple Sclerosis study as a healthy control candidate. they took blood and performed an MRI of my brain. I've also done a few psychological research studies.PositiveI've never been purposely infected with anything before.Very OftenYes, I donate annuallyYesYesNoSlightly likely5Slightly likely5If my family is very upset about it or if it significantly impacts my work.Somewhat likelySomewhat negativelyany information you can provide that guarantee some protection would be helpful for me to explain to my family.N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:156/10/20 11:441001786True6/10/20 11:44I AgreeNoFrom a radio advertisement.I thought it was a good idea. I have since reconsidered.As soon as I heardStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat disagreeSomewhat agreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat disagreeNoI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeGetting seriously ill, and privacyconcerns about getting seriously ill and dying.N/AHelping others833 in 100 (33.3%)1233000A littleA great deal5510 in 100 (10%)10100001 - I would not accept any additional risk11 in 100,000 (0.001%)114 - There is a moderate risk to me433 in 100 (33%)12330004 - There is a moderate risk to me420 in 100 (20%)1120000335 in 100 (5%)95000Between 50 million and 100 million infections41189297750045Fairly likely6Fairly likely6YesTo members of my family.They thought it was too risky, particularly for someone my age.TrueTrueTrueFalseFalseNeverMore than onceNo, I have notNoYesNoFairly unlikely2Fairly unlikely2Risk of getting seriously ill and/or being intubated.NeutralSomewhat negativelyQuantify a low risk of getting sick.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:166/10/20 11:441001698True6/10/20 11:44I AgreeYesWatching the news and via social mediaThat it is very important and I may be a perfect candidate to helpAlmost immediatley after I researched the validity of the siteStrongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeI am young, healthy, and I live aloneI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveNeither agree nor disagreeBeing infected with anything always brings risks of health issues that may otherwise not have happened and the burden of following infection study protocol which may be more restrictive than normal life Neither concern me that muchNeither concern me that muchThe ability to potentially be part of important research that can save lives220 in 100 (20%)1120000A moderate amountA moderate amount221 in 100 (1%)81000665 in 100 (5%)950003310 in 100 (10%)1010000221 in 100 (1%)81000221 in 10,000 (0.01%)310Between 20 million and 50 million infections 2001132506920Somewhat likely5Fairly likely6NoTrueFalseFalseTrueFalseNeverVery OftenYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7I would research the methods being used and if they are not ethicallys afe I may not participateFairly unlikelyFairly positivelyproviding you with information about the study to share with others that shows it is scientifically as safe as possibleN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:166/10/20 11:451001732True6/10/20 11:45I AgreeYesNews list serve called The SkimmI like the idea of action versus inaction. I wanted to take part. More or less immediately Strongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeI am single and live away from family. I have no dependents or husband. I have less to lose than someone else. I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat disagreeIsolation from my normal life, prolonged weakness physically. Isolation from friends and loved ones Physical weakness/death - does not feel likely to meHelp a vaccine happen sooner! Contribute to society71 in 100 (1%)81000A great dealA great deal221 in 1,000 (0.1%)5100331 in 1,000 (0.1%)51004 - There is a moderate risk to me410 in 100 (10%)1010000221 in 1,000 (0.1%)5100221 in 10,000 (0.01%)310Between 20 million and 50 million infections 36410622021888Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseMore than oncePsychology StudiesPositivePhysically infected with a virus Often Yes, I have on occasionUnsure/I don’t knowYesNoFairly unlikely2Fairly unlikely2Loss of job Somewhat likelySomewhat positivelyProvide information, market the study as humanitarian N/AN/AN/AN/AMildN/AN/AMildN/A
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Volunteer6/10/20 11:216/10/20 11:451001441True6/10/20 11:45I AgreeYesI think I saw an article online while I was at work.I thought that it sounded interesting and like something that I would totally do.ImmediatelyStrongly agreeStrongly agreeSomewhat agreeSomewhat agreeStrongly agreeSomewhat disagreeSomewhat agreeSomewhat agreeNeither agree nor disagreeIt gives me some certainty with my future with the virus, which kind of helps to soothe my anxietyI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveStrongly disagreeI mean I think that there could be a lot of complications that are not very predictable. Death being the worst, isolation and anxiety being the most likely.Isolation and anxiety honestlySerious side effects, though I know they are possibleHelping to move medicine and the process of vaccination forward85 in 100 (5%)95000A lotA lot551 in 10,000 (0.01%)310551 in 100 (1%)810004 - There is a moderate risk to me433 in 100 (33%)1233000331 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 10,000 (0.01%)310More than 250 million infections79691273417802Somewhat likely5Somewhat likely5NoTrueTrueFalseFalseFalseNeverVery OftenYes, I have on occasionYesYesNoExtremely likely7Extremely likely7Significant events in my life that came up, new health concernsSomewhat likelySomewhat negativelyPRoviding information would be greatN/AN/AN/AN/AN/AMildN/AN/AMild
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Volunteer6/10/20 11:106/10/20 11:451002088True6/10/20 11:45I AgreeYesI read about it in an online article. I'm not sure of the source, perhaps CNN.I thought it was a very good idea because we need to develop a vaccine as soon as possible so we can save lives, and also give the overall population a sense of security to resume their normal lives.I initially made the decision immediately, but then thought about it some more. Within a day I was committted.Strongly agreeStrongly agreeSomewhat agreeStrongly disagreeStrongly agreeStrongly disagreeStrongly disagreeSomewhat agreeNeither agree nor disagreeI want our world to have a vaccine as soon as possible.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveStrongly disagreeBeing away from your home for several weeks and out of your normal routine. Not seeing friends and family. Then if I receive the placebo I will get COVID-19 and will become sick. While I am a very healthy individual, there is always a chance I could get COVID-19 severely and die. I have a great deal of confidence that I will be well cared for by those conducting the study, however. If I do contract COVID-19 I do wonder if there are any long-lasting health effects. And of course there's also the possibility that the vaccine that we're testing doesn't work and it will take longer to develop a vaccine. That would be very disappointing.The possibility of death.Getting sick with the disease to a mild degree.The opportunity to help get a vaccine sooner.720 in 100 (20%)1120000A great dealA great deal221 in 100 (1%)810004 - I would accept a moderately greater level of risk420 in 100 (20%)1120000221 in 100 (1%)810002210 in 100 (10%)10100001 - There is no risk to me11 in 100,000 (0.001%)11Between 5 million and 20 million infections 715971020000Extremely likely7Extremely likely7YesFamily and friends.Thought it was interesting, but none of them would be willing to do it.TrueTrueFalseFalseFalseNeverOften Yes, I have on occasionNoYesNoFairly likely6Fairly likely6Work concerns.NeutralSomewhat negativelyPerhaps a video explaining it that I could show people.N/AN/AN/AN/AN/AMildN/AN/AMild
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Volunteer6/10/20 11:326/10/20 11:46100843True6/10/20 11:46I AgreeYesI saw an ad on the internet.I was interested because I wanted to be able to help.I thought I wanted to participate immediately.Strongly agreeSomewhat agreeStrongly agreeNeither agree nor disagreeSomewhat agreeStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeI have compassion for those suffering.I want to help others and potentially save lives,I was curious about COVID-19,I wanted to contribute to the progress of medicineStrongly disagreeThe fact that I do not know how my body will react to COVID-19 and that it could be detrimental to my own health. It would also be a burden if I am unable to help.Long-term effects from COVID-19The time involved in the studyHelping to find a way to treat COVID-19 in an effective manner.31 in 5,000 (0.02%)420A moderate amountA moderate amount221 in 50,000 (0.002%)22551 in 100 (1%)810005510 in 100 (10%)10100001 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me1Less than 0.001%00Between 5 million and 20 million infections 10102122567848Somewhat likely5Fairly likely6NoTrueTrueFalseTrueFalseNeverMore than onceNo, I have notNoYesNoFairly likely6Fairly likely6Exposure to a more infectious strain of the diseaseExtremely likelyFairly negativelyShare how much this could help the entire global populationN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:036/10/20 11:471002646True6/10/20 11:47I AgreeYesI saw people talking about it on Twitter. I think it was a tweet from Robert Wiblin.It sounded like a good idea, and important for efforts to fight the virus.I took a day or two to think about it.Strongly agreeSomewhat agreeStrongly disagreeNeither agree nor disagreeStrongly agreeSomewhat disagreeStrongly disagreeSomewhat disagreeStrongly disagreeI was unemployed, so I didn't have other important commitments or projects that the COVID-19 study would interfere with. I'm young (24) and have no underlying conditions, so I believe I would be low risk of death from the trial.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagree-Risk of unpleasant illness, lung damage, death, or other effects of contracting COVID-19.
-Risk of side effects from the experimental vaccine.
-Unpleasantness and inconvenience of being in isolation for several weeks during the study.		Risk of death or lasting injury from being infected.Unpleasantness and inconvenience of being in isolationThe gratification of knowing that I am contributing to the project of developing a lifesaving vaccine.410 in 100 (10%)1010000A great dealA lot331 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk45 in 100 (5%)950006633 in 100 (33%)1233000221 in 1,000 (0.1%)5100221 in 5,000 (0.02%)420Between 50 million and 100 million infections510089510089Extremely unlikely1Extremely unlikely1YesMy motherShe thought it seemed like a good thing to volunteer for.TrueTrueFalseFalseFalseMore than onceVarious psychology and behavioral economics studies.Extremely positiveI anticipate it would pose much greater risks, be much more unpleasant, involve a much greater time commitment, and be more emotionally rewarding.NeverYes, I have on occasionNoYesNoFairly likely6Neither likely nor unlikely4If the informal cost/benefit analysis changes - for instance, if I'm busy with some other project that I don't want to postpone, if I come to believe the risks are much greater than I currently do, or if a highly effective treatment is discovered such that vaccine development becomes less urgent.Fairly unlikelyVery positivelyProvide information to share, especially information about the care I would be given if I develop severe symptoms.N/AN/AN/AN/ASevereN/AN/AMildN/A
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Volunteer6/10/20 11:126/10/20 11:471002116True6/10/20 11:47I AgreeYesI heard about it via newspapers and media generallyThat it is important that those who can, try their best to find a way to cure the worlds population from this virus. Even though a human trial might have its cons, the pros are so much more important and my hope is to be a small part on the path of developing a life-saving vaccine. I made the decision immediately after I read about this trial.Strongly agreeSomewhat agreeNeither agree nor disagreeStrongly agreeStrongly agreeNeither agree nor disagreeStrongly disagreeSomewhat disagreeStrongly disagreeNot anything other than the fact that I want to help in any way I can. So i thought why not try to be a part of this trial that will be som important for all of us in the future.I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeMaybe the thought of never knowing for sure that it will be okay. even though it is under a controlled environment, you can never be a hundred percent sure. But it is not a big scare for me, because I know that it, most likely, will be fine.Having som form of complication. Even though the risks for that happening are minimalDying, being scared, having pain.The feeling of having been part in an important study that could save many lives.11 in 1,000 (0.1%)5100A great dealA great deal1 - There is no risk to me11 in 100,000 (0.001%)114 - I would accept a moderately greater level of risk41 in 100 (1%)81000221 in 5,000 (0.02%)420221 in 1,000 (0.1%)51001 - There is no risk to me1Less than 0.001%00Between 2 million and 5 million infections353779576299Fairly likely6Extremely likely7YesMy parentsThey where okay with it, even though parents always will be scared for their children if they become sick. But it is for a good cause, so I have their supportTrueTrueFalseFalseFalseNeverNeverYes, I donate annuallyNoYesNoFairly likely6Fairly likely6If it has a big impact on me not being able to work for a long periode of time (more than 2months)Somewhat unlikelyFairly positivelyEnough information about the environment the study would take place in, the procedures etc.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:106/10/20 11:471002264True6/10/20 11:47I AgreeYesRead an article online while I was doing research on the pandemic.I felt it might be the quickest way to finding a vaccine for it.I thought about it for about 15 minutes and felt it would be something I would be able to do.Strongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeStrongly disagreeThere's not much I can do right now to help the healthcare system in any other way. Since I have been made redundant from my old position and am not currently employed, I felt I could dedicate my time trying to assist in the search for a vaccine.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineNeither agree nor disagreeSince we are still learning details about how it affects people, I could be part of the population that has an unfavorable outcome during the study. Based on the positive tests for infections versus fatalities, I don't feel the risk of death is high enough to keep me from wanting to help.Possible permanent organ damage if the reports are true about negative long term affects.Becoming ill with symptoms that don't require hospitalization.Being monitored and getting necessary medical care during the study.55 in 100 (5%)95000A moderate amountA moderate amount221 in 100 (1%)810005510 in 100 (10%)1010000221 in 1,000 (0.1%)5100221 in 10,000 (0.01%)3101 - There is no risk to me1Less than 0.001%00Between 5 million and 20 million infections 476674632612Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseNeverMore than onceYes, I have on occasionNoYesNoExtremely likely7Fairly likely6If I had to quit a job to do it. Currently I'm unemployed and willing to participate.Somewhat unlikelySomewhat negativelyMy family would be concerned and potentially be upset.N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:026/10/20 11:481002730True6/10/20 11:48I AgreeYesSomeone I followed on Twitter tweeted about it.I wanted to learn more to see if it was something I could realistically participate in or contribute to.I read through the material on the 1 day sooner website and after roughly 15 minutes of thinking it over, I signed up.Strongly agreeSomewhat agreeSomewhat agreeSomewhat disagreeSomewhat disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeN\AI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I was curious about COVID-19Strongly disagreeMy main concern is the risk of long term health effects of contracting the virus. We don't know if having Covid could permanently damage my lungs or if lingering effects could cause me health issues later in life. I also risk enduring significant pain and discomfort while I recover.My long term health.Pain and discomfortIt could save a lot of lives.41 in 1,000 (0.1%)5100A lotA lot221 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk410 in 100 (10%)10100003320 in 100 (20%)1120000221 in 10,000 (0.01%)3101 - There is no risk to me1Less than 0.001%00Between 50 million and 100 million infections50708006453533Neither likely nor unlikely4Neither likely nor unlikely4NoTrueTrueFalseFalseFalseNeverMore than onceYes, I donate annuallyNoYesNoFairly likely6Slightly likely5If the timing conflicts with my personal or professional life in a way that I cannot work around. Fairly likelyFairly positivelyThe more information I can provide about the possible risks and possible benefits to society, the better. I want them to see why I have concluded it is worthwhile and worth the risk.N/AN/AN/AN/AN/AN/AN/AMildMild
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Volunteer6/10/20 11:136/10/20 11:481002104True6/10/20 11:48I AgreeYesI saw a story about it on the internet and did a search.I wanted to be involved since I'm in good health.I made the decision immediately.Strongly agreeSomewhat disagreeNeither agree nor disagreeStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeStrongly disagreeNoneI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeThere is a risk of adverse affects.None - I'm not particularly concerned at all.NoneHelping the advancement of medicine.21 in 1,000 (0.1%)5100A great dealA moderate amount221 in 50,000 (0.002%)22331 in 100 (1%)810003310 in 100 (10%)1010000221 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 20 million and 50 million infections 866518498951Somewhat likely5Fairly likely6NoTrueFalseTrueFalseFalseNeverOften Yes, I have on occasionYesYesNoExtremely likely7Extremely likely7If there was a HIGH probability that I would catch Covid-19 and have serious health issues as a result of the study.NeutralVery positivelyJust what you said -- provide information about the study to share. That being said, I have little family, and it's my decision.N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:066/10/20 11:481002556True6/10/20 11:48I AgreeYesNIH Website and subsequent call for volunteersI’m an oncology nurse so my first reaction was “makes sense” then “can I participate?”Immediately Strongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeMy belief in nursing & medical research in advancing the effectiveness in healthcare I want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to contribute to the progress of medicineStrongly disagreeSevere risk is becoming infected and symptomatic and requiring inpatient medical care-oxygen>ICU>intubation; minor risk is becoming infected and symptomatic but only requiring stay-at-home remediesRequiring hospitalization Minor symptomsHighly educated healthcare team providing individualized care and resources650 in 100 (50%)1350000A moderate amountA moderate amount4 - There is a moderate risk to me41 in 100 (1%)810005520 in 100 (20%)1120000221 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 1,000 (0.1%)5100221 in 1,000 (0.1%)5100Between 5 million and 20 million infections 405321510000000Neither likely nor unlikely4Somewhat likely5YesDaughterSupportiveTrueTrueFalseTrueFalseNeverMore than oncePrefer not to sayNoYesNoExtremely likely7Extremely likely7Can’t think of anything that would make me not participate Somewhat likelyNeutralProviding info to share with others N/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:016/10/20 11:481002852True6/10/20 11:48I AgreeYesA news article sent to me by my motherA desire to be part of itImmediately, but I had been thinking about how to become infected in order to have antibodies so that I could safely interact with my elderly mother following a quarantine period.Strongly disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeSomewhat disagreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeStrongly disagreeObtain immunity so that I can no longer spread the disease to friends and family.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,Another factor I identified aboveDisagreeTime, physical discomfort, quarantine, childcare during quarantine, risk of complications or death.DeathPhysical discomfortImmunity11 in 500 (0.2%)6200A moderate amountA moderate amount221 in 1,000 (0.1%)5100331 in 100 (1%)810005533 in 100 (33%)1233000221 in 50,000 (0.002%)22221 in 100,000 (0.001%)11Between 100 million and 250 million infections396596810000000Somewhat unlikely3Somewhat unlikely3YesMy mother and a coworkerGrudging acceptanceTrueFalseFalseFalseTrueNeverNeverNo, I have notNoNoNoExtremely likely7Extremely likely7My mother's health, if it deterioratesSomewhat likelyFairly positivelyProvide info on how long infection could last and about efficacy of antibodiesN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:166/10/20 11:491001928True6/10/20 11:49I AgreeYesIn a news article online about responses to COVID-19It is necessary in order to move forwardimmediatelyStrongly agreeStrongly agreeSomewhat agreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeThinking that participants of all ages are needed.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I was curious about COVID-19DisagreeThis is a serious disease that needs more study. It isn't known how any given individual will respondThere is a risk with any Covid infection right now. I might have a more serious caseI'm not comfortable hiding away from riskImmediate response to any complications65 in 100 (5%)95000A great dealA great deal221 in 100 (1%)810007 - I would accept a seriously greater level of risk75 in 100 (5%)95000221 in 100 (1%)81000221 in 1,000 (0.1%)5100221 in 250 (0.4%)7400Between 100 million and 250 million infections60013172069464Fairly likely6Extremely likely7YesMy best friendThey had reservations but accepted my decisionTrueTrueFalseFalseFalseNeverMore than onceNo, I have notNoNoNoFairly likely6Fairly likely6If there were a family crisis or if I developed a different serious health issueFairly unlikelySomewhat negativelyThink my grown children would be upset with my choice. More information might helpN/AMildMild
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Volunteer6/10/20 11:126/10/20 11:491002205True6/10/20 11:49I AgreeYesI have been trying to learn what I can about treatment and vaccine development. Although the timeline for vaccine development has been accelerated, I know that one of the delays is that after the vaccine enters the human trial phase, the common practice is to wait to see if any of the subjects naturally contracts the virus. I read in a newspaper article about the ethical barriers to a challenge trial.it was a necessary step to speed the time to the development of a vaccineI had heard about the ethical barriers to a challenge trial about a week before hearing about the 1 Day Sooner list. I enrolled right awayStrongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeSomewhat agreeStrongly disagreeStrongly disagreeSomewhat disagreenoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeThe largest risk is that the vaccine is ineffective and my immune system is weaker than I think and the impact of the virus is severe. The largest burden is the potential to have to spend 2 weeks in isolation. The risk of isolationThe severity of the virus on my systemThe search for a vaccine proceeds more quickly - especially as incidence in some countries is declining quickly making natural infection less likely51 in 1,000 (0.1%)5100A lotA lot221 in 10,000 (0.01%)310331 in 1,000 (0.1%)51004 - There is a moderate risk to me41 in 100 (1%)81000221 in 100,000 (0.001%)1122Less than 0.001%00Between 5 million and 20 million infections 80062282036049Fairly likely6Fairly likely6Yesmy husbandHe also signed up with 1 Day SoonerTrueTrueFalseFalseTrueMore than oncePrior studies were observational in nature - both health and psychologySomewhat positiveI have never participated in a study that would affect my health or put me at riskOnceYes, I have on occasionNoYesNoFairly likely6Fairly likely6I would be less likely to participate if I had to travel to another location and then stay there for a significant period of timeFairly unlikelySomewhat positivelyproviding information about risks and the procedure would be importantN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:006/10/20 11:501003002True6/10/20 11:50I AgreeYesTelevision news story highlighting volunteers for the study.I thought it was a good way for non-medical workers to contribute to the fight against Covid.1 day after hearing about it in April. I just made sure that it would be feasible to continue working from home.Strongly disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat disagreeStrongly agreeSomewhat agreeSomewhat agreeI have friends no one can visit because of preexisting conditions. If we can speed the Vaccine up we can help them get back to their lives quicker.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveDisagreeSmall risk of death due to the disease.

Lasting health problems such as damage to lungs or kidneys from being put on life support.

Loss of income from extended illness

Potential to spread the infection to family		DeathLoss of incomePotential to find a Vaccine21 in 100 (1%)81000A great dealA great deal331 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk41 in 100 (1%)81000331 in 100 (1%)810004 - There is a moderate risk to me41 in 100 (1%)81000221 in 50,000 (0.002%)22Between 20 million and 50 million infections 39004922528939Extremely likely7Extremely likely7Yesmy fatherThey didn't have much of an opinionTrueTrueTrueFalseFalseMore than onceeffects of KT tape on knee strength performancePositivemuch greater risk+hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhohpVery OftenYes, I have on occasionNoYesNoExtremely likely7Extremely likely7Already existing vaccineSomewhat likelySomewhat positivelyN/AN/AN/AN/AMildMildN/AMildMild
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Volunteer6/10/20 11:176/10/20 11:501001978True6/10/20 11:50I AgreeYesTwitter than going to the 1daysooner websiteSounds like a way I could helpLess than an hour after hearing about it. Strongly agreeStrongly agreeSomewhat agreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat disagreeStrongly disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat disagreeSerious pneumonia, requiring hospitalization. Infecting othersInfecting otherspneumonialikely Immunity either from the vacine or virus. 75 in 100 (5%)95000A great dealA great deal221 in 100 (1%)81000551 in 100 (1%)81000221 in 1,000 (0.1%)51001 - There is no risk to me11 in 1,000 (0.1%)51001 - There is no risk to me11 in 100,000 (0.001%)11Between 50 million and 100 million infections26457301143724Somewhat likely5Somewhat likely5YesMy spouseNervous, but understanding.TrueTrueTrueFalseFalseNeverOften Yes, I have on occasionYesYesNoFairly likely6Fairly likely6Discovery of personal health issue raising my risk. Somewhat unlikelySomewhat positivelyproviding you with information N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:016/10/20 11:501002947True6/10/20 11:50I AgreeYesI read about it online, and it sounded like a good way to face this thing head on, rather than cowering at home and waiting for someone else to do it.That it seems necessary and might speed up the process of getting a vaccine out to people.I didn't actually enroll in any study yet. Just submitted my info as a potential volunteer.Strongly agreeSomewhat agreeStrongly disagreeStrongly disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeSomewhat agreeNeither agree nor disagreeI live alone, so it's less likely I'd infect others if I were to become infected. Also, I could probably take time/leave from my job if needed. And, I'm tired of us all living in fear--some bold steps are needed.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,Another factor I identified aboveStrongly disagreeBeing in the control/placebo group and catching COVID-19 with serious symptoms that cannot be treated effectively. Being in the treatment group and the vaccine doesn't work and I catch infection with serious symptoms when there is little in the way of effective treatment. Alternatively, having an unexpected reaction to the vaccine such that it makes one MORE susceptible to the virus (or to other illnesses) than if you hadn't had the vaccine. Having to be careful around others while I'm in the trial so as to not infect someone else if the vaccine doesn't work for me.Catching COVID-19 with serious symptoms requiring hospitalization.Having to be careful around others while in the trial.Going ahead and being exposed to the virus in a controlled way rather than being fearful of catching it casually. Helping speed up the process of getting a vaccine to others who are more vulnerable.610 in 100 (10%)1010000A great dealA great deal221 in 100 (1%)81000225 in 100 (5%)950005533 in 100 (33%)12330004 - There is a moderate risk to me420 in 100 (20%)1120000221 in 250 (0.4%)7400Between 5 million and 20 million infections 49765851378884Fairly likely6Fairly likely6NoTrueTrueTrueFalseFalseMore than onceSocial science study on attitudes, focus groups, etc.PositiveI haven't participated in a health-related study beforeNeverYes, I donate annuallyNoYesNoFairly likely6Extremely likely7Family concerns, lack of support from my workplace (although I think they would be), cold feet if the risks are a lot different (worse) than I think right now.Somewhat unlikelyNeutralYes, providing information to share with them, as well as the medical precautions being taken.N/AN/AN/AN/AN/AMildN/AMildN/A
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Volunteer6/10/20 11:096/10/20 11:501002498True6/10/20 11:50I AgreeYesOnline in a news report but I don't remember where or from what website. Might have been via Apple News.I recognized its clinical importance and that there is a need for a vaccine sooner or later as many individuals are suffering from not only the disease but from economic hardships related to how society has needed to scale back normal activity related to the need to stop the spread of the disease in the absence of a vaccine.Not long after I read about the initiative. I recognized its importance and that my individual circumstances would lend itself to volunteering for the endeavor.Strongly agreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeI'm a registered nurse who has worked in health car and in particular hospice - I don't have fear of the disease or contracting the disease related to my healthcare experience and own physical health.I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveSomewhat disagreeRisks: Adverse side-effects of the vaccine. The vaccine not working and having a difficult to manage respiratory case of COVID as opposed to a mild case.
Although it is not a factor for me, I feel it may be a burden for individuals to have to be isolated in a clinical study center.		The vaccine not working and having a difficult to manage case of COVIDIsolation at a clinical centerKnowing that you've possibly contributed to the welfare of others.51 in 10,000 (0.01%)310A great dealA great deal221 in 50,000 (0.002%)224 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)5100221 in 50,000 (0.002%)221 - There is no risk to me11 in 100,000 (0.001%)111 - There is no risk to me1Less than 0.001%00Between 5 million and 20 million infections 14234382303371Fairly likely6Somewhat likely5NoTrueTrueFalseFalseTrueNeverOnceYes, I have on occasionNoNoNoFairly likely6Fairly likely6I'm not sure and my decision to take part would be based on the particulars of the study.NeutralSomewhat negativelySharing any information that is okay to share would help.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:026/10/20 11:511002910True6/10/20 11:51I AgreeYesThe radio, I think? Maybe NPR. Sign me up. It says I need to have at least 25 characters in this answer so, here you go. It was an immediate decision. I am concerned about a rushed vaccine process and a government approval process under the current president, but if anyone needs to test it, it should be someone like me who is relatively young, healthy, still has a job and health insurance, no kids, etc. Strongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeI would be influenced by who is running it. I was hoping it would be something out of the Medical College of Wisconsin because I trust them, as opposed to a private pharmaceutical group. I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeDeath. Time commitment. Infecting others. Long term health problems from unknown complications or side effects. Death. Time. Helping others81 in 500 (0.2%)6200A great dealA great deal221 in 1,000 (0.1%)5100665 in 100 (5%)95000221 in 50,000 (0.002%)22221 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 20 million and 50 million infections 30162284943170Fairly likely6Fairly likely6NoTrueTrueFalseFalseFalseNeverVery OftenYes, I donate annuallyYesYesNoFairly likely6Fairly likely6Who is running it, evidence of what sort of safety measures have been taken before moving to human trials. Dr. recommendation. Somewhat likelySomewhat positivelyYes, lots of information. Maybe a meeting with the Dr.s and anyone from the family who wishes to speak with them. This is my biggest concern for participation is how my family would feel about it. N/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:046/10/20 11:511002810True6/10/20 11:51I AgreeYesCNN. I watched a report about the efforts upcoming and some underway. Curiosity on how I can help. First reaction was yes. Then thought about it and spoke to my family. Ultimately decided it was the right thing to do. Strongly agreeSomewhat disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeStrongly disagreeStrongly disagreeStrongly disagreeFelt consistent and right in my heart. I want to help others and potentially save lives,I wanted to contribute to the progress of medicine,Another factor I identified aboveStrongly disagreeIsolation and unable to work and provide. That we never find a effective vaccine. Impact financially on my loved ones. I guess it would be that my trial does not prove effective. I believe even in failure things can be learned. Education85 in 100 (5%)95000A moderate amountA moderate amount4 - There is a moderate risk to me41 in 10,000 (0.01%)3107 - I would accept a seriously greater level of risk730 in 100 (33.3%)12330004 - There is a moderate risk to me433 in 100 (33%)1233000331 in 1,000 (0.1%)510022Less than 0.001%00Between 5 million and 20 million infections 1049683864868Fairly likely6Fairly likely6YesMy familyThey were scared but understood this to something I would likely do. TrueTrueTrueTrueFalseNeverOnceYes, I donate annuallyYesYesNoExtremely likely7Extremely likely7Not sureFairly likelyNeutralFamily, friends, and employer. I agree that documentation for a clear understanding that I could provide to them and the motives. N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:186/10/20 11:511001972True6/10/20 11:51I AgreeYesNature Journal "https://www.nature.com/"I thought it was a good idea. The idea of speeding up vaccine trials makes the most sense in the present situation I feel.Immediately, I don't have any of the known risk factors that complicate the disease.Strongly agreeStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat agreeNot that I can think of, I think the biggest influence is I didn't want to be helpless. I wanted to do something meaningful to help people during this time. Just staying at home, while it does flatten the curve, doesn't seem to help much. People are still scared, people are still dying. I'm not in the group that is at risk, I think I can help.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat agreeI believe the main risks and burdens for me, a healthy 25 year old Caucasian female, would be that I might come down with flu symptoms for a week or two and I would have to be quarantined while infected which would be inconvenient but doable. The worst case scenario I feel was that I overestimated my immune strength and I get very sick or I suppose while the risk is very very small I could still die. Honestly though, if that is what happens than it likely would have happened if I got exposed to the disease outside the laboratory so is it additional risk? I'm not so sure.Well death would suck.Coming down with flu like symptoms is a yearly thing so while it's not great it's doable.I would be an active member in helping eradicate this disease. That'd be pretty satisfying. 21 in 1,000 (0.1%)5100A moderate amountA moderate amount221 in 100,000 (0.001%)11665 in 100 (5%)950006650 in 100 (50%)13500002220 in 100 (20%)11200001 - There is no risk to me11 in 10,000 (0.01%)310More than 250 million infections30385048396071Fairly likely6Extremely likely7YesMy boyfriend and my sisterThey thought it was a good idea and wanted to sign up tooTrueTrueFalseFalseFalseMore than oncePsychology related research, ranging from prevalence rates of sexual assault on campus and PTSD measurements to insomina research.PositiveI think it would be more involved and intensive. You'd need to control for a lot of factors and a human challenge study would be watched closely by IRB and the media, if something went wrong or the results were questionable it would be disastrous not just for the current study but for future studies like it. It is imperative that this is done right.OnceYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7I am joining the military this summer, there is a chance they might stop me from joining the study.Fairly unlikelySomewhat positivelyI think pamphlets explaining the study, previous animal trials and what will be done if something goes wrong. They might also want someway to contact me while I'm in the study say via email or something.N/AN/AN/AN/AN/AN/AN/AN/ASevere
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Volunteer6/10/20 11:296/10/20 11:511001350True6/10/20 11:51I AgreeYesI heard about it on Twitter from rationalist community accounts.I wanted to help with vaccines being brought to market sooner.Almost immediatelyStrongly agreeSomewhat disagreeStrongly disagreeStrongly disagreeSomewhat agreeSomewhat disagreeStrongly disagreeStrongly disagreeNeither agree nor disagreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywayDisagreeContracting COVID-19; subsequent health problems from the virus, such as lung scarring; dangers from untested vaccine components. Long term health consequences from contracting the virus, such as lung damage.Vaccine component related dangers.Helping to advance a vaccine earlier than otherwise possible.51 in 1,000 (0.1%)5100A moderate amountA moderate amount221 in 50,000 (0.002%)227 - I would accept a seriously greater level of risk71 in 100 (1%)810005510 in 100 (10%)1010000221 in 10,000 (0.01%)310221 in 100,000 (0.001%)11Between 20 million and 50 million infections 25595544007545Fairly likely6Fairly likely6NoTrueTrueTrueTrueFalseMore than onceVarious psychological and behavioral studies.Neither positive nor negativeI have never done a study that involved receiving a vaccine or medical treatment.More than onceYes, I donate annuallyYesYesNoFairly likely6Fairly likely6If it involved significant time away from work.Somewhat likelySomewhat negativelyExplain the relevant risks and rewards in clear terms.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:096/10/20 11:521002599True6/10/20 11:52I AgreeYesFstoppers.com YouTube videoGreat idea to help precipitate the process to save lives. Took a few weeks to think about it Strongly agreeStrongly agreeStrongly agreeStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat disagreeSomewhat agreeSomewhat disagreeJust want to help in a positive way I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeThe risk of a very long recovery is a concern of mine. I’ve seen stories of recoveries that took months. The unknown time element. Getting sick. I understand that risk. Being a reliable subject to provide good data. 61 in 5,000 (0.02%)420A littleA little331 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk71 in 100 (1%)81000331 in 50,000 (0.002%)22331 in 100,000 (0.001%)1122Less than 0.001%00Between 5 million and 20 million infections 80275529057935Somewhat likely5Somewhat likely5YesMy wife and sons. Hesitant but supportive. TrueFalseFalseFalseFalseNeverVery OftenYes, I donate annuallyUnsure/I don’t knowYesNoExtremely likely7Extremely likely7NeutralSomewhat positivelyTell your story and share progress N/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:286/10/20 11:531001511True6/10/20 11:53I AgreeYesi read a news report onlineseems like a good idea. Human testing appears to be a reasonable method of speeding up our response to the trial. immediatelySomewhat agreeSomewhat agreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeSomewhat agreeStrongly disagreeSomewhat agreeSomewhat disagreeI would like early access to the vaccine itselfI want to help others and potentially save lives,I wanted to be part of a clinical trial,I wanted to be guaranteed access to critical care should I be infected with COVID-19DisagreeIsolation from friends and family, death or serious long term illness from the virus, deathisolationclosely watched medical care, potential early access to vaccine61 in 500 (0.2%)6200A lotA great deal331 in 10,000 (0.01%)3104 - I would accept a moderately greater level of risk41 in 1,000 (0.1%)5100221 in 5,000 (0.02%)4201 - There is no risk to me11 in 100,000 (0.001%)1122Less than 0.001%00Between 5 million and 20 million infections 76497992303371Fairly likely6Fairly likely6Yesmy parentsit was unclearTrueTrueFalseFalseFalseNeverNeverYes, I have on occasionNoYesNoSlightly likely5Extremely likely7scheduling, family objectionsSomewhat likelySomewhat negativelyprovide concrete analysis of the risks, particularly in relation to the statistical risks of everyday activities. N/AN/AN/AN/AN/AN/AN/AN/AMild
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Volunteer6/10/20 11:206/10/20 11:531001989True6/10/20 11:53I AgreeYesOn the internet, I clicked a link and read about it. It needs to be done. There is too much misinformation, inaccurate statements and people need to see some well put together results and actions.I had been thinking about the need for some time and I responded same day after reading about the studyStrongly agreeStrongly disagreeNeither agree nor disagreeSomewhat agreeStrongly agreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeSomewhat agreeNoI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I am likely to be infected with COVID-19 anywaySomewhat agreeHaving some condition that I am not aware of , and perhaps no one is aware of, that makes me more susceptible to a more significant and serious bout of the disease.
As a result , dying. 		not being aware of a condition that makes this more serious for me dyingExcelllent healthcare personnel are monitoring your conditions620 in 100 (20%)1120000A great dealA great deal221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk410 in 100 (10%)10100006690 in 100 (90%)15900004 - There is a moderate risk to me450 in 100 (50%)1350000221 in 1,000 (0.1%)5100Between 20 million and 50 million infections 46869879654710Extremely likely7Extremely likely7YesSpouse, colleagues , friends They are concerned it is risky, and they see the importance. TrueFalseFalseFalseFalseNeverVery OftenYes, I donate annuallyNoYesNoExtremely likely7Extremely likely7If it brought risk to my family or friends Fairly unlikelyFairly positivelyInformation of the study and the ability to access me by vid or web or have regular communication N/AN/AN/AN/AMildN/AN/ASevereN/A
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Volunteer6/10/20 11:276/10/20 11:531001608True6/10/20 11:53I AgreeYesIn a news article in the Montreal GazetteI was excited. I had just seen a documentary on epidemics and I was desperate to help.Immediately.Strongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeSomewhat disagreeSomewhat disagreeSomewhat disagreeSomewhat disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineSomewhat disagreeThere is a risk that I may become severely ill or even die. It may affect my health for the rest of my life. I would have to be away from my partner to protect her from getting the illness.DeathGetting COVIDContributing to society 91 in 250 (0.4%)7400A lotA great deal221 in 10,000 (0.01%)3107 - I would accept a seriously greater level of risk71 in 1,000 (0.1%)51004 - There is a moderate risk to me420 in 100 (20%)1120000331 in 100,000 (0.001%)111 - There is no risk to me1Less than 0.001%00More than 250 million infections537963010000000Fairly likely6Somewhat likely5YesMy partnerShe was upset I signed upTrueTrueTrueFalseFalseMore than onceBrain scans and music researchPositiveThere would be risk to meNeverNo, I have notUnsure/I don’t knowYesNoSlightly unlikely3Slightly unlikely3My partners disapprovalFairly likelySomewhat positivelyPerhaps more details about the risks for them and how long I would be awayN/AN/AN/AN/AN/AMildN/AN/AN/A
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Volunteer6/10/20 11:226/10/20 11:541001960True6/10/20 11:54I AgreeYesI heard about it through an article online.I thought that it was a good idea, as the risk to younger people is lower, and that this could shave months off of the vaccine development time. I made the decision immediacy, with the caveat that I hadn't officially signed up for anything. I was just expressing interest.Strongly agreeStrongly agreeSomewhat agreeSomewhat agreeStrongly agreeSomewhat disagreeSomewhat agreeStrongly agreeStrongly disagreeI want this pandemic to be over as soon as possible, so the world can resume normal life, and I can visit my friends.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,Another factor I identified aboveDisagreeI would think that the main risks would be for an overreaction of the immune system to a vaccine, and of course there is always a chance that I could develop severe symptom, or even multisystem inflammatory syndrome, which could be life threatening.MIS, and being severely ill for a long period of time.My body overreacting to the vaccine.Getting top of the line care if I did develop Covid-19 or related symptoms. 41 in 500 (0.2%)6200A great dealA great deal221 in 1,000 (0.1%)51004 - I would accept a moderately greater level of risk41 in 100 (1%)810004 - There is a moderate risk to me410 in 100 (10%)10100001 - There is no risk to me11 in 100,000 (0.001%)11221 in 10,000 (0.01%)310Between 20 million and 50 million infections 911072521228Neither likely nor unlikely4Fairly likely6YesMy parents and RabbiThey were and still are very concerned with me knowingly exposing myself to Covid-19TrueTrueFalseFalseFalseNeverNeverNo, I have notUnsure/I don’t knowPrefer not to sayNoNeither likely nor unlikely4Fairly unlikely2Concerns regarding both my health, and the inability to be around my family and friends for an extended period of time.Extremely likelySomewhat negativelyInformation showing how I would be in all likelihood safe from adverse affects. N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:256/10/20 11:541001781True6/10/20 11:54I AgreeYesA news article talking about why we should rethink challenge trialsCuriosity of its efficacy versus risksI made it immediately after researching the benefit versus risk breakdown Strongly agreeStrongly agreeSomewhat disagreeNeither agree nor disagreeSomewhat agreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly disagreeAs a Christian I believe that it is important to act to help people, and if I can help do something practical to help others, I mustI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreePotential unknown side effects of a vaccine, potential to become infected with CovidPotential for infectionPotential side effectsHelping a vaccine develop as quickly and effectively as possible61 in 100 (1%)81000A great dealA great deal221 in 1,000 (0.1%)51007 - I would accept a seriously greater level of risk730 in 100 (33.3%)12330003320 in 100 (20%)1120000221 in 1,000 (0.1%)5100221 in 5,000 (0.02%)420Between 20 million and 50 million infections 38070546012455Fairly likely6Fairly likely6YesMy parentsThey thought it was riskyTrueTrueFalseFalseFalseMore than onceTo study something about human psychologyNeither positive nor negativeIt would involve more invasive and physical demandsOnceYes, I donate annuallyYesYesNoFairly likely6Fairly likely6Questions about the legitimacy of those running the study, or being unable to set aside the proper time commitmentSomewhat likelySomewhat negativelyBreakdown of the need for the study, the legitimacy of it and those running it, and information about vaccine efficacy, safety and importanceN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:266/10/20 11:541001684True6/10/20 11:54I AgreeYesI don't remember. I'd assume I saw it somewhere online or in an email.My first reaction was interest. There has been so much information about Covid-19 but its cconstantly changing because little is actually known about the virus and it's spread.Immediate interestStrongly agreeSomewhat disagreeSomewhat agreeSomewhat agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeI think that studies of this type are important.I want to help others and potentially save lives,I was curious about COVID-19,I wanted to contribute to the progress of medicineSomewhat disagreeThe main risk is that you are exposed to a virus and the vaccine does not work. There is the possibility of becoming very sick. The burden is being exposed to a virus and not having contact with familyObviously I don't want to get sick.I'd be foolish not to be concerned but there are no guarantees that I wouldn't get the virus anyway.The ability to contribute to research that may help me and others be safer.51 in 5,000 (0.02%)420A lotA great deal221 in 10,000 (0.01%)310221 in 1,000 (0.1%)51004 - There is a moderate risk to me450 in 100 (50%)1350000331 in 1,000 (0.1%)5100221 in 100,000 (0.001%)11Between 100 million and 250 million infections23917902853827Fairly likely6Somewhat likely5NoTrueTrueTrueTrueFalseNeverNeverYes, I donate annuallyNoYesNoFairly likely6Fairly likely6After reading all information to the study if I learn of unconsidered factors I may choose not to participateSomewhat likelyNeutralProviding information and being transparent on all outcomes related tobtrialN/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:326/10/20 11:551001357True6/10/20 11:55I AgreeYesArticle shared by a family friendIt was necessary and seemed like a good ideaImmediately - it is needed to get a vaccineStrongly agreeStrongly agreeNeither agree nor disagreeSomewhat agreeStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeSomewhat agreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeGetting very sick, or permanent lasting effects/disability or deathDisabilityGetting sickBeing taken care of and monitored by professionals81 in 1,000 (0.1%)5100A great dealA great deal221 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk71 in 1,000 (0.1%)51003310 in 100 (10%)101000066Greater than 90%169500022Less than 0.001%00Between 5 million and 20 million infections 20026346023594Extremely likely7Extremely likely7YesFamily friend Thought it was an interesting ideaTrueTrueTrueFalseFalseMore than onceEconomics and psychology studies in collegePositiveMedical, I would be physically affectedOften Yes, I donate annuallyYesYesNoExtremely likely7Extremely likely7If it required enough time investment that I couldn’t continue working and may lose my incomeSomewhat likelySomewhat negativelyStatistics of the expected risks and what would happen If I did get sickN/AN/AN/AN/AN/AFatalN/AN/AN/A
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Volunteer6/10/20 11:306/10/20 11:551001512True6/10/20 11:55I AgreeYesFacebook and other social mediaI support anything that can ethically speed up vaccine or treatment development for Covid-19.ImmediatelyStrongly agreeNeither agree nor disagreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeSomewhat disagreeNeither agree nor disagreeStrongly disagreeSomewhat disagreeI want to help others and potentially save lives,I wanted to contribute to the progress of medicine,I wanted to receive financial reimbursement for participatingStrongly disagreeHospitalization or death.DeathHospitalizationIt would be ethically conducted with strict candidate selection.420 in 100 (20%)1120000A lotA lot221 in 100 (1%)810005510 in 100 (10%)10100003333 in 100 (33%)1233000331 in 100,000 (0.001%)11221 in 100 (1%)81000More than 250 million infections41746212403616Fairly likely6Fairly likely6YesFriends and familyThere were mixed reactions with most wanting more specifics and details.TrueTrueFalseFalseFalseNeverNeverNo, I have notNoYesNoFairly likely6Neither likely nor unlikely4If it would negate my life insurance policyFairly unlikelySomewhat positivelySpecific information and detailsN/AN/AN/AN/AN/AN/AN/AMildN/A
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Volunteer6/10/20 11:036/10/20 11:551003141True6/10/20 11:55I AgreeYesI saw a news story on CNN about the Human Challenge Trial.I immediately wanted to sign up for the Human Challenge Trial. After the CNN story, I googled the Human Challenge Trial and found their website, where I submitted my contact information.Strongly agreeStrongly agreeNeither agree nor disagreeNeither agree nor disagreeStrongly agreeNeither agree nor disagreeStrongly disagreeSomewhat agreeNeither agree nor disagreeI want to do my part to help find an effective vaccine. Also, I am a non-white woman in my 40s, a demographic that may not be well-represented in the Human Challenge trials.I want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeThere are the obvious risks of illness, lasting effects of the illness, and death caused by the vaccine or by the COVID-19 infection. There may be negative effects of the vaccine that may not appear until decades later, such as cancer or shorter lifespan. Also, there may be a risk of unintentionally infecting my husband or others. I would definitely self-quarantine and avoid contact with other people during the clinical trial. But, my husband may catch the infection from me, and he could possibly spread it to others.I am most concerned about spreading the virus to my husband and other people, and I am very concerned about long-lasting health issues that make me a burden on my loved ones who may need to care for me and pay for care.I am least concerned about getting infected with the virus, as I consider myself relatively healthy, and I will have better access to healthcare than other people who are not participating in the clinical trial.I will be doing my part to bring about an effective vaccine for the rest of the world. Even if I die, my death will help scientists find another effective vaccine.51 in 50,000 (0.002%)22A littleA moderate amount221 in 100,000 (0.001%)117 - I would accept a seriously greater level of risk71 in 100 (1%)810003310 in 100 (10%)1010000221 in 100 (1%)81000221 in 10,000 (0.01%)310Between 5 million and 20 million infections 710580120246Fairly likely6Fairly likely6Yesmy husband, who completely supports my participation in a Human Challenge trialHe strongly supports my participation in a Human Challenge trial. He would sign up himself, but he is our breadwinner and our source of health insurance, so we cannot risk illness or death for him.TrueFalseTrueFalseFalseNeverNeverYes, I have on occasionNoYesNoExtremely likely7Extremely likely7I cannot think of a reason why I would not enroll.Somewhat likelyFairly positivelyProviding me with information about whether I risk infecting other people by participating in the clinical trial.N/AN/AN/AN/AN/AN/AN/AN/AN/A
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Volunteer6/10/20 11:356/10/20 11:571001269True6/10/20 11:57I AgreeYesFrom an online science news aggregator, RealClearScienceWhatever it takes to get a vaccine out sooner. I believe I’m low-risk so happy to help.ImmediatelyStrongly agreeStrongly disagreeStrongly disagreeStrongly disagreeStrongly agreeStrongly disagreeStrongly disagreeSomewhat agreeSomewhat disagreeNoI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineDisagreeBeing away from family, possibly having serious case of covidBeing away from familySerious complicationsHelping others61 in 500 (0.2%)6200A lotA lot221 in 1,000 (0.1%)5100551 in 1,000 (0.1%)51006620 in 100 (20%)1120000221 in 5,000 (0.02%)420221 in 10,000 (0.01%)310Between 50 million and 100 million infections30140001517000Fairly likely6Fairly likely6YesMy wifeSome reservations but supportiveTrueTrueFalseFalseFalseNeverMore than onceYes, I donate annuallyYesYesNoExtremely likely7Extremely likely7NothingFairly likelySomewhat positivelyInfo on the actual risks. Up to date data especially. Also, would want to know treatment options in case I got serious infection.N/AN/AN/AN/AN/AN/AN/AMildMild
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Volunteer6/10/20 11:136/10/20 11:571002647True6/10/20 11:57I AgreeYesI googled "volunteer COVID vaccine" Positive. I believe this is what is needed to hyper speed up the process of making sure we attain herd immunity from an otherwise highly contagious virus. I took some time to think about it. I have three children, after all. But I also have great faith in our scientists working on COVID vaccines. Strongly agreeSomewhat agreeNeither agree nor disagreeNeither agree nor disagreeSomewhat agreeNeither agree nor disagreeStrongly disagreeNeither agree nor disagreeSomewhat disagreeI want to help others and potentially save lives,I feel helpless and this is a way to do something positive,I wanted to contribute to the progress of medicineStrongly disagreeI believe the main risks are that there's always a chance the infection could become deadly.

Another burden would be having to be in a controlled setting for two weeks, but I am willing to handle that burden.		Working with people I don't know personally, in a vulnerable situation, at least initially. Being poked and prodded. I went through a year worth of infertility treatments and three pregnancies so I am used to that. :]Having a team of experts look out for my health while hoping to better scientific research. 51 in 1,000 (0.1%)5100A great dealA lot221 in 50,000 (0.002%)22551 in 10,000 (0.01%)3104 - There is a moderate risk to me41 in 100 (1%)81000221 in 100,000 (0.001%)1122Less than 0.001%00Between 2 million and 5 million infections59456256669621Somewhat likely5Somewhat likely5YesSpouse.They reminded me that it requires being put into isolation and extends further than simply getting a vaccine and being exposed to the virus. Basically, that the tip of the iceberg is just the tip. Below the surface it's a much bigger deal.TrueTrueFalseFalseFalseOnceI am currently working with the NIH, an online study called NIMH COVID-19 about the effects on one's mental health during a pandemic over the course of six months. PositiveThe one I do now is answering questions online. This one would be substantially more "hands on" for lack of a better phrase. More than onceYes, I have on occasionUnsure/I don’t knowYesNoFairly likely6Extremely likely7Extended amount of time away from family, beyond, say two weeks. Somewhat unlikelyNeutralSharing information, definitely. Also: previous studies that went exceptionally well. Basically, a relatively awesome resume. N/AN/AN/AN/AMildN/AN/AMildN/A