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「麻布大学における研究活動上の不正行為に関する調査結果について（概要）」表よりPEACE作成　2025.3.8更新
List of Papers by Associate Professor Shinobu Wakui of Azabu University Identified as Involving Misconduct
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麻布大調査No.年
Year		撤回等
Retraction		論文タイトル
Tittle		ジャーナル名
Journal 		巻
Volulme		号
Number		認定された不正
Certified Misconduct		使われた動物
Kind of animals		犠牲動物数※
Number of animals used		NIH・PHSガイドライン表記DOI・URL本文有料論文の入手著者一覧備考
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第一次調査
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ー2021ーIn-Utero and Lactational 3,3',4,4',5-Pentachlorobiphenyl Exposure Dose-dependently Increase N-butyl-4-(hydroxybutyl) Nitrosamine Rats Urinary Bladder CarcinomaThe Journal of Toxicological Sciencesーー捏造
改ざん
不適切なオーサーシップ		ラット不明不明ーーー不明出版前、リジェクト済み
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第二次調査
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12017懸念表明In Utero Exposure to Di(n-butyl)phthalate Induces Morphological and Biochemical Changes in Rats PostpubertyToxicologic Pathology454改ざんラット440匹以上あり
https://doi.org/10.1177/0192623317709091
OPENYuya Okayama, Shin Wakui, Michael F. Wempe, Mitsuru Sugiyama, Masaya Motohashi, Tomoko Mutou, Hiroyuki Takahashi, Eisuke Kume, and Hiroshi Ikegami
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22017撤回済
2024.8.6		Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinomaMicroscopy663捏造
不適切なオーサーシップ		ラット24匹ありhttps://doi.org/10.1093/jmicro/dfx008OPENEisuke Kume, Tomoko Mutou, Norio Kansaku, Hitoyuki Takahashi, Michael F. Wempe, Masahiro Ikegami, Yoshikatsu Kanai, Hitoshi Endou, Shin Wakui
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32016Three-Dimensional Study of the Terminal Portion in Sprague-Dawley Rat Ejaculatory DuctsAnatomia, Histologia, Embryologia 454不適切なオーサーシップラット有料にて
未確認		有料にて未確認https://doi.org/10.1111/ahe.12196有料×M. Motohashi, T. Inomata, H. Takahashi, N. Ichihara, N. Kansaku, M. Ikegami, M. Asari, T. Mutou, S. Wakui
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42016撤回済
2023.6.6		In utero-exposed di(n-butyl) phthalate induce dose dependent, age-related changes of morphology and testosterone-biosynthesis enzymes/associated proteins of Leydig cell mitochondria in ratsThe Journal of Toxicological Sciences412捏造　改ざん
自己盗用
不適切なオーサーシップ		ラット220匹以上ありhttps://doi.org/10.2131/jts.41.195OPENMasaya Motohashi, Michael F. Wempe, Tomoko Mutou, Yuya Okayama, Norio Kansaku, Hiroyuki Takahashi, Masahiro Ikegami, Masao Asari, Shin WakuiPubPeer
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7 2016Male rats exposed in utero to di(n-butyl) phthalate: Age-related changes in Leydig cell smooth endoplasmic reticulum and testicular testosterone-biosynthesis enzymes/proteinsReproductive Toxicology59捏造
改ざん
不適切なオーサーシップ		ラット有料にて
未確認		有料にて未確認
https://doi.org/10.1016/j.reprotox.2015.12.001
有料×Masaya Motohashia Michael F. Wempe Tomoko Mutou Hiroyuki Takahashi Norio Kansaku Masahiro Ikegami Tomo Inomata Masao Asari Shin Wakui
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8 2015Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-
(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis bioassay		Journal of Applied Toxicology352捏造ラット有料にて
未確認		有料にて未確認https://doi.org/10.1002/jat.3021有料×Shin Wakui, Tomoko Mutou, Hiroyuki Takahashi, Masahiro Ikegami, Hideki Wanibuchi, Shoji Fukushima
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9 2015懸念表明Adenocarcinoma of the Ampullary Glands of the Ductus Deferens in a Sprague-Dawley RatToxicologic Pathology434捏造
不適切なオーサーシップ		ラット1ありhttps://doi.org/10.1177/0192623314554266OPENMasaya Motohashi, Shin Wakui, Hiroyuki Takahashi, Ayaka Yoshida, Tomoko Mutou, Masahiro Ikegami, Masao Asari, and Tomo Inomata
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10 2015Three-dimensional reconstruction of deferent ducts papillae in urogenital duct system of the male ratProstate756不適切なオーサーシップラット有料にて
未確認		有料にて未確認https://doi.org/10.1002/pros.22948有料×Shin Wakui, Masaya Motohashi, Tomo Inomata, Nobutsume Ichihara, Tomoko Mutou, Hiroyuki Takahashi, Masahiro Ikegami, Masao Asari
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12 2014懸念表明Effects of in utero exposure to di(n-butyl) phthalate for estrogen receptors α, β, and androgen receptor of Leydig cell on ratsToxicologic Pathology425捏造
改ざん
不適切なオーサーシップ		ラット110匹以上あり
https://doi.org/10.1177/0192623313502879
OPENShin Wakui, Masaru Shirai, Masaya Motohashi, Tomoko Mutou, Noriko Oyama, Michael F. Wempe, Hiroyuki Takahashi, Tomoo Inomata, Masahiro Ikegami, Hitoshi Endou, and Masao Asari
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13 2013撤回済
2023.10.7		Nuclear Morphometric Analysis of Leydig Cells of Male Pubertal Rats Exposed In Utero to Di(n-butyl) PhthalateJournal of Toxicologic Pathology264捏造
不適切なオーサーシップ		ラット110匹以上ありhttps://doi.org/10.1293/tox.2013-0031OPENShin Wakui, Masaya Motohashi, Takemi Satoh, Masaru Shirai, Tomoko Mutou, Hiroyuki Takahashi, Michael F. Wempe, Hitoshi Endou, Tomoo Inomata, Masao Asari
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14 2013懸念表明Male Sprague-Dawley rats exposed to in utero di(n-butyl) phthalate: Dose dependent and age-related morphological changes in leydig cell smooth endoplasmic reticulumToxicologic Pathology417捏造
改ざん
不適切なオーサーシップ		ラット180匹以上あり
https://doi.org/10.1177/0192623312474725
OPENMasaru Shirai, Shin Wakui, Michael F. Wempe, Tomoko Mutou, Noriko Oyama, Masaya Motohashi, Hiroyuki Takahashi, Norio Kansaku, Masao Asari, Hiroshi Hano, and Hitoshi Endou
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15 2013懸念表明Atypical Leydig Cell Hyperplasia in Adult Rats with Low T and High LH Induced by Prenatal Di(n-butyl) Phthalate ExposureToxicologic Pathology413捏造
不適切なオーサーシップ		ラット46匹以上あり
https://doi.org/10.1177/0192623312457272
OPENShin Wakui, Hiroyuki Takahashi, Tomoko Mutou, Masaru Shirai, Promsuk Jutabha, Naohiko Anzai, Michael F. Wempe, Norio Kansaku, Hiroshi Hano, Tomo Inomata, and Hitoshi Endou
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16 2012Sertoli cells proliferate in adult rats with prenatal exposure to 3,3 ',4,4 ',5-pentachlorobiphenylArchives of Toxicology86捏造ラット90匹以上あり
https://doi.org/10.1007/s00204-011-0736-8
有料〇Shin Wakui, Tomoko Muto, Yoshihiko Suzuki, Hiroyuki Takahashi & Hiroshi Hano
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17 2011Sex-Associated Difference in Estrogen Receptor β Expression in N-Methyl-N′-Nitro-N-Nitrosoguanidine-Induced Gastric Cancers in RatsComparative Medicine615捏造ラット72匹ありhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193063/OPENShin Wakui, Masaya Motohashi, Tomoko Muto, Hiroyuki Takahashi, Hiroshi Hano, Promsuk Jutabha, Naohiko Anzai, Michael F Wempe, Hitoshi Endou6
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23 2006Localization of Ang-1, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesisLaboratory Investigation86捏造ラット40匹あり
https://www.laboratoryinvestigation.org/article/S0023-6837(22)01769-X/fulltext
OPENShin Wakui, Kiyofumi Yokoo, Tomoko Muto, Yoshihiko Suzuki, Hiroyuki Takahashi, Masakuni Furusato, Hiroshi Hano, Hitoshi Endou & Yoshikatsu Kanai
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24 2006Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP1A1 1B1 and AhR by 7,12-dimethylbenz[a]anthraceneToxicology and Applied Pharmacology2103捏造ラット405匹以上ありhttps://doi.org/10.1016/j.taap.2005.04.022有料〇Shin Wakui, Kiyofumi Yokoo, Hiroyuki Takahashi, Tomoko Muto, Yoshihiko Suzuki, Yoshikatsu Kana,i Hiroshi Hano, Masakuni Furusato ,Hitoshi Endou
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27 2002Mammary gland differentiation in female rats after prenatal exposure to 3,3',4,4',5-pentachlorobiphenylToxicology1772-3不適切なオーサーシップラット276匹以上あり
https://doi.org/10.1016/S0300-483X(02)00224-X
有料〇Tomoko Muto, Shin Wakui, Noboru Imano, Kenji Nakaaki, Hiroyuki Takahashi ,Hiroshi Hano, Masakuni Furusato, Toshio Masaoka
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28 2022懸念表明In Utero Exposure to 3,3',4,4', 5-Pentachlorobiphenyl Dose-Dependently Induces N-butyl-4-(hydroxybutyl) Nitrosamine in Rats With Urinary Bladder CarcinomaToxicologic Pathology503改ざんラット有料にて
未確認		有料にて未確認
https://doi.org/10.1177/01926233211064180
有料×Shin Wakui, Hiroyuki Takahashi, and Tomoko Muto第一次調査の論文と同一の実験
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29 2022Prenatal exposure to di(n-butyl) phthalate delays the spermatogenic cycle in rats: Investigation using a BrdU-injection methodReproductive Toxicology109捏造
不適切なオーサーシップ		ラット有料にて
未確認		有料にて未確認
https://doi.org/10.1016/j.reprotox.2022.01.003
有料×Shin Wakui, Daisuke Sato, Yuya Okayama, Norio Kansaku, Tomoko Muto
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30 2017撤回済
2023.6.6		Quantitative morphometric analysis of vimentin filaments in Sertoli cells of rats after in utero DBP exposureFundamental Toxicological Sciences42捏造ラット176匹以上ありhttps://doi.org/10.2131/fts.4.85OPENEisuke Kume, Yuya Okayama, Mituru Sugiyama, Hiroyuki Takahashi, Tomoko Muto, Michael F. Wempe, Hiroshi Ikegami, Shin Wakui
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31 2017In vitro thermoreversible gel disc quantitative assay of rat angiogenesis.Alternatives to Animal Testing and Experimentation162捏造ラット6匹ありhttps://doi.org/10.11232/aatex.16.59OPENShin Wakui, Tomoko Muto, Naohiko Anzai, Hiroyuki Takahashi, Promsuk Jutabha, Akihiko Sakata, Michael F. Wempe, Hiroshi Hano, Hitoshi Endou
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※Materials and methodsからの推定。産子のうち間引かれた数が不明なものなどを「以上」とした
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