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CONFERENCE PROGRAM

ECR DAY

MONDAY

16TH

Sponsor arrival and access setup

09:00 - 12:00

11:30 - 12:30

Registration and lunch

Arrival, poster setup and lunch

12:30 - 12:40

Welcome address

12:40 - 13:00

Christopher Stewart

Newcastle University - The academic path

17:30 - 19:00

ECR Networking drinks

Northern Stage

14:20 - 15:00

Coffee break

Caitlin Richardson

Martina Miotto

Ramarketing - The industry path

CellRev - Spinning out from university

Stacey Wagstaff

AI and research integrity

Christina Lord

13:00 - 14:00

14:00 - 14:20

15:10 - 15:30

15:30 - 17:00

The early researcher burnout

15:00 - 15:10

Midlands Innovation EV network

We need your invaluable help! Scan for something cool.

Chair: Charlotte Lawson

Chair: Hannah Jackson

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Welcome address

09:50 - 10:00

10:00 - 10:40

Plenary talk: An Hendrix

10:40 - 11:40

Selected talks

11:40 - 12:00

Coffee break

Lunch break

Sponsor talks: Beckman Coulter | Particle Metrix

12:30 - 13:00

13:00 - 14:00

09:40

Registration

12:00 - 12:30

Selected talks

10:40 - 10:55 Ms Fatma Busra Isik (University of Nottingham)- Plasma small extracellular vesicles enriched for microglial origin as biomarkers for dementia with Lewy bodies

10:55 - 11:10 Mr Meir Kestecher (Semmelweis University/HCEMM)- Reduced circulating CD63+ extracellular vesicle levels associate with atherosclerosis in hypercholesterolaemic mice and humans

11:10 - 11:25 Dr Rahul Mahida (University of Birmingham) - Extracellular vesicles mediate macrophage metabolic dysfunction in fibrotic and inflammatory lung diseases.

11:25 - 11:40 Miss Katie Spencer (University of Birmingham)- Pulmonary extracellular vesicles drive alveolar macrophage dysfunction in Acute Respiratory Distress Syndrome

12:00 - 12:15 Ms Morganne Wilbourne (University of Oxford)- Characterizing the contribution of miRNA cargo from syncytiotrophoblast-derived extracellular vesicles to the pathogenesis of pre-eclampsia

12:15 - 12:30 Dr Maurizio Renna (University of Naples)- The HSPB1-p62/SQSTM1 functional complex regulates the EVs-mediated unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein

FORUM

TUE 17TH

MORNING

UKEV2024

SPONSORS

Chair: Oksana Kehoe and Rahul Sanwlani

Chair: Naveed Akbar

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FORUM

TUE 17TH

AFTERNOON

19:00 - 21:00

Dinner at Newcastle Civic Centre

15:10 - 15:40

Coffee break

Lightning talks

15:40 - 16:40

16:40 - 17:10

14:00 - 14:40

Plenary talk: Kenneth Witwer

Sponsor talks: Cytek | Exodus Bio | Cellarcus Biosciences

14:40 - 15:10

Selected talks

17:10 - 18:30

Poster session and drinks

21:00 - onwards

After dinner drinks at Pleased to Meet You

15:40 - 15:55 Dr Saskia Bakker (University of Warwick)- Cryo-TEM as a characterisation method for extracellular vesicles in dairy products

15:55 - 16:10 Professor Nicholas Turner (University of Sheffield)- Monitoring the electroactive cargo of extracellular vesicles can differentiate various cancer cell lines

16:10 - 16:25 Miss Lucinda Cruddas (UCL)- Do small extracellular vesicles (sEVs) have a role in chronic diabetic foot ulcers?

16:25 - 16:40 Dr Yağmur Yıldızhan (University of Cambridge)- The molecular basis of exosome tethering

Ms Himadri Devvanshi - Unveiling the potential of placental-enriched small extracellular vesicles as modulators of immune homeostasis in spontaneous preterm birth

Ms Alice Hodge - Symptomatic Menopausal Women Not Responding to Hormone Replacement Therapy May Increase their Bone and Cardiovascular Risk: A Pilot Study Investigating Extracellular Vesicle Protein Cargo

Miss Charlotte Boyd - Exposure of Extracellular Vesicles to Hyperglycaemic Conditions Alters Surface Characteristics and Cellular Uptake

Miss Mimma Maggio - Multi-Targeted Bone Regeneration: The Role of Bone-Derived Matrix Vesicles

Miss Krishalle Richmond - Impact of downstream bioprocessing on identity and immunomodulatory potency of Mesenchymal stromal cells derived extracellular vesicles

Dr Elizabeth Dellar - Optimising immunocapture of extracellular vesicles from cerebrospinal fluid for biomarker discovery in neurodegenerative diseases

Dr Abigail Byford - Maternal Extracellular Vesicles Promote Fetal Overgrowth in Pregnancies Complicated by Gestational Diabetes

Miss Georgina Thompson - Small Extracellular Vesicles Released by Cardiac Fibroblasts from Hypertrophic Cardiomyopathy Patients Alter Calcium Transients and Contribute to Hypertrophy of Human Cardiomyocytes

Miss Jessica Willis - Selective attenuation of extracellular vesicle secretion from prostate cancer cells

Dr Rahul Sanwlani - ALK5 inhibitor SD-208 exhibits antifibrotic activity by reverting myofibroblasts to fibroblasts in hypertrophic cardiomyopathy and inhibits small extracellular vesicle secretion

Chair: Andrew Devitt

Chair: Tim Williams and Demi Pritchard

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09:20 - 10:00

Plenary talk: Lorraine O’Driscoll

10:00 - 10:30

Selected talks

11:00 - 11:20

Coffee break

Lunch break

AGM

12:55 - 13:45

12:00 - 12:30

14:15 - 14:40

09:00 - 09:20

Coffee

11:20 - 12:00

Plenary talk: Rossella Crescitelli

13:45 - 14:15

Panel: Future directions for EV research in the UK and beyond

Sponsor talks: IZON | ONI | NanoFCM

10:30 - 11:00

Selected talks

14:40 - 15:00

Awards and closing remarks

Lightning talks

12:30 - 12:55

FORUM

WED

18TH

10:00 - 10:15 Dr Emily Clarke (University of Liverpool)- Interleukin 1B priming induces an anti-inflammatory mesenchymal stem cell phenotype and extracellular vesicle response: Implications for NIK-dependent mechanisms and equine musculoskeletal therapies

10:15 - 10:30 Dr Soraya Williams (Loughborough University)- Comparative Profiling of Mesenchymal Stem Cell Extracellular Vesicles for Application in Regenerative Dermatology

12:00 - 12:15 Professor Tim Williams (University of Cambridge)- Investigating the abundance of antimicrobial proteins in subtypes of human urinary extracellular vesicles

12:15 - 12:30 Miss Noelia Pelegrina-Hidalgo (University of Edinburgh)- Visualising Parkinson's disease at the nanoscale

Dr Ritu Raj - Extracellular Vesicles as Key Cellular Messengers: Integrating Inflammation and Tissue Repair Processes

Miss Mimma Maggio - Extracellular vesicles from mesenchymal-derived bone cells regulate osteoclastogenesis

Miss Emily Moss - Isolation and characterisation of breast cancer patient-derived stromal extracellular vesicles

Dr Joshua Price - Intercellular Signalling in Obesity: Adipose-Derived EV miRNA communicate with skeletal muscle

Ms Claire Catherine Staton - Novel class of Non-Vesicular Extracellular Particle (NVEP) identified while analyzing EV subpopulations

Dr Demi Pritchard - Utilising extracellular vesicle glycoproteins for early detection of patients with clinically significant prostate cancer

Ms Natalie Jiraskova - Circulating extracellular vesicles in the pregnant ewe and fetus during late gestation

Miss Hannah Beattie - Does the expression of CD63 in extracellular vesicles present in serum alter between different thyroid pathologies?

Dr Mathieu Y. Brunet - Development of Melt Electrowritten Fibrous Scaffolds with Controlled Release of Osteocyte-derived Extracellular Vesicles for Bone Repair

Chair: Nick Peake

Chair: Jason Webber and Rachel Butler