From CAD Creation to Post-processing: Stenosed Carotid Artery: Hemodynamics with Ansys Discovery & Ansys Fluent Softwares
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Learning Objectives
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Intended Learning Outcomes | |
Knowledge and Understanding | Analyze and interpret hemodynamic results to understand their clinical significance in vascular disease Understand Mesh Quality and its acceptable ranges Locate poor mesh elements |
Skills and Abilities | Know how to create an anatomically accurate straight stenosed vessel Apply Local Sizing in the mesh on areas of interest Set up and Solve non-Newtonian blood flow simulations |
Values and Attitudes | Appreciate the importance of simulation accuracy when modeling physiological flows Develop critical thinking when interpreting CFD results in a biomedical context |
Further reading/information
Ansys software mentioned |
|
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This tutorial guides you through the complete workflow of creating, simulating, and analyzing blood flow through a stenosed blood vessel using Ansys Software. Starting with geometry creation in Ansys Discovery software, you'll progress through meshing with boundary layer refinement, setting up a physiologically accurate non-Newtonian blood flow simulation in Ansys Fluent software, and performing post-processing analysis of critical hemodynamic parameters.
The tutorial emphasizes practical aspects of biomedical CFD modeling, including implementation of Boundary Conditions, configuring non-Newtonian blood rheology models, and interpreting clinically relevant flow parameters through Post-processing such as wall shear stress distributions and recirculation zones. Special attention is given to the step-by-step CAD creation and Mesh Quality in the stenotic region to accurately capture flow separation, recirculation, adverse pressures and more, that occur in atherosclerotic vessels.
Through step-by-step instructions and detailed explanations, you'll develop a deep understanding of both the technical simulation workflow and the physiological significance of your results, bridging the gap between computational methods and biomedical applications.
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/ About
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Notes: This section provides additional context to support educators in teaching this material.
Content: Follow the step-by-step process outlined in the slides, using the screenshots from Ansys Discovery & Fluent software for guidance.
/ How To Use This Tutorial
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Section 2 – CFD Simulation with the Ansys Fluent software
Meshing:
Solver:
Section 1 – CAD Creation with the Ansys Discovery tool
Main Features:
/ Overview
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Section 1 – CAD Creation with Ansys Discovery Software
Main Features:
Sketching, Pull, Move, Blend, Named Selections and Exporting.
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Section 1.1 – Dimensions
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Parameter | Typical Values, Dimensions |
Artery length | ~50 - 100 mm |
Normal diameter | 6 - 8mm |
Stenosed diameter | 50% narrowing (3 mm) |
Stenosis length | 3 - 10 mm |
45 mm
45 mm
10 mm
Length = 100 mm
Give it a try and create the body yourself using these dimensions
Note: Make sure you create your Named Selections! Page 18 – 23
Step 0 consist of defining the desired model dimensions based on typical Carotid Artery size ranges.
Note: ‘Bold’ Parameters are the ones used for the tutorial
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Start a Sketch by clicking in the ‘Design’ tab, the ‘Sketch’ button
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Note: If Sketch is already selected, the plane Z will be the default plane. To change this, press the key ‘D’ and follow the steps:
D
Click the x-axis during plane selection for sketching
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CAD
Section 1.2 – Sketching
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In the ‘Design’ tab, Click the ‘Circle’
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Click at the origin of the x-axis to start the sketching in the selected plane. Type 6 mm and press ‘Enter’
Leave ‘Sketch’ by pressing:
D
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5
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Section 1.2 – Sketching
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Select the Tab ‘Measure’ and Click on ‘Measure’
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Click on the Circle’s edge you just sketched. Check ‘Circle Diameter’ is equal to 6mm
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Section 1.3 – Measure Tool (Bonus)
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Click and Copy the ‘Circle’ pressing:
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Paste the ‘Circle’ in the same position pressing:
Select ‘Move’ by pressing:
And drag in the x-direction by ‘press and dragging’ the ‘blue arrow’
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10
Ctrl
C
Ctrl
V
M
When the dimension box appears, type 45 mm and press ‘Enter’
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Section 1.4 – Move Tool
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Section 1.4 – Move Tool
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Click ‘Select’ in the ‘Design’ Tab and Repeat Steps 8-10 in the new surface that was moved
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When the dimension box appears, type 5 mm (Mid Stenosis) and press ‘Enter’
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Click ‘Select’ in the ‘Design’ Tab and Repeat Steps 8-10 in the new surface that was moved
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When the dimension box appears, type 10 mm (Mid Stenosis) and press ‘Enter’
Note: for consistency, the Second Circle is the one copied and pasted
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Section 1.4 – Move Tool
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Click ‘Select’ in the ‘Design’ Tab and Repeat Steps 8-10 in the new surface that was moved
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When the dimension box appears, type 55 mm
Note: for consistency, the Second Circle is the one copied and pasted
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Section 1.4 – Move Tool
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Click ‘Pull’ in the ‘Design’ Tab
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Click the edge of the last Circle (3rd from left to right)
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Click the arrow normal to the edge and type -1.5 mm (To achieve a diameter of 3 mm, since the value given is pull on Radius)
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Note: You can check the measure is correct (3 mm of diameter) by using the ‘Measure’ tab
Section 1.5 – Pull Tool
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In ‘Pull’, Click the first ‘Circle’
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Press the ‘Up to’ Box (Shown in red)
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Click the Second Circle of 6 mm
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Section 1.5 – Pull Tool
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Click ‘Blend’ in the ‘Design’ Tab
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Click the Second Circle of 6 mm, Third Circle of 3 mm and Fourth Circle of 6 mm holding:
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Click the ‘Complete blending’ Green Check
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Ctrl
a
b
c
Section 1.6 – Blend Tool
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Repeat Steps 21-23 but from Firth to Fourth Circle (In that order)
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Section 1.7 – Pull Tool 2
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Click Select in the ‘Design’ Tab
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Open ‘Named Selection’
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Click the First Circle, Add a new Named Selection (Red Circle) and Change the name to ‘inlet’
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‘inlet’
Velocity Inlet
Section 1.8 – Named Selections
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Repeat Step 30 for the following surface:
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‘wall.1’
Pre-stenotic wall
Section 1.8 – Named Selections
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Repeat Step 30 for the following surface:
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‘wall.2’
Post-stenotic wall
Section 1.8 – Named Selections
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Repeat Step 30 for the following surface:
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‘stenosis’
Stenosis’ wall
Section 1.8 – Named Selections
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Repeat Step 30 for the following surface:
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‘outlet’
Pressure Outlet
Section 1.8 – Named Selections
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Make sure your Named Selections look like this:
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If Yes, save your CAD model in your desired folder
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Congratulations, your CAD model is completed!
End
Section 1.8 – Named Selections
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Section 2 – CFD Simulation with Ansys Fluent Software
Meshing:
Solver:
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Make sure ‘Meshing’ is selected
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Toggle Double Precision
Meshing Processes → 2 or more
Solver Processes → 2 or more
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Press ‘Start’!
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a
b
c
Mesh
Section 2.0 – Launching Ansys Fluent Software
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Successful Launch
Section 2.0 – Launching Ansys Fluent Software
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Reasoning: These areas experience complex flow behaviors – high-velocity jets, recirculation zones, and potential turbulence. Boost convergence stability 15-20 Cells per gap ensures sufficient detail capturing. Since 20 cells in a gap of 3 mm and 6 mm will produce elements of approximately 0.15 mm and 0.30 mm, respectively. Why not 50? Mesh count scales approximately n³ in 3D, increasing total cell count by approximately (50/20) ³ = 15.6 times!
Reasoning: We want accurate near-wall flow modeling.
Section 2.1 – Mesh Specifications
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Select Watertight Geometry
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Import the Geometry:
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Section 2.2 – Mesh
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Successful CAD import
Section 2.3 – Mesh Generation
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Add local Sizing at the Throat ‘stenosis’
Change Size Control Type to ‘Proximity’,
And Cells Per Gap to ’20’
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Click ‘Add local Sizing’ and make sure it displays at the workflow tree as shown below
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Set Local sizing to ‘yes’ and follow the steps:
b
a
c
d
Section 2.3 – Mesh Generation
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Add local Sizing at the post-stenotic region ‘wall.2’
Change Size Control Type to ‘Proximity’,
And Cells Per Gap to ’20’
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Click ‘Add local Sizing’ and make sure it displays at the workflow tree as shown below
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b
a
c
d
Section 2.3 – Mesh Generation
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Generate the Surface Mesh using default values, by clicking ‘Generate the Surface Mesh
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Check Surface Mesh Quality in the Console: Maximum Skewness: 0.47 (Good)
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Section 2.3 – Mesh Generation
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Successful Surface Mesh Generation
Section 2.3 – Mesh Generation
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Describe the geometry:
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a
b
c
Section 2.3 – Mesh Generation
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Update Boundaries:
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Section 2.3 – Mesh Generation
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Update Region:
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Section 2.3 – Mesh Generation
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Add Boundary Layers:
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a
b
Section 2.3 – Mesh Generation
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Generate the Volume Mesh:
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End
Section 2.3 – Mesh Generation
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Successful Volume Mesh Generation
Section 2.4 – Volume Mesh
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Local Sizing Results using Polyhedral Mesh Elements (Default Value)
@ Stenosis ‘Throat’
Local Sizing ‘Proximity’
@ Inlet & wall.1
No Local Sizing
@ Outlet & wall.2
Local Sizing ‘Proximity
Section 2.4 – Volume Mesh
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The mesh consists of a network of cells and nodes of various shapes and sizes. These cells serve as discrete control volumes where the governing Partial Differential Equations (PDEs) are solved to approximate the flow solution.
Meshing often presents a trade-off between accuracy and computational cost. A finer mesh provides more accurate results but requires more computational resources.
So, how can we make sure our mesh will provide accurate result while maintaining computational low. Keeping both time of simulation and mesh elements low?
Evaluating Aspect Ratio, Skewness and Orthogonality of the mesh elements, a conclusion can be made regarding the mesh capabilities to produces accurate results.
To expand further, a description of these parameters is provided, including their acceptable ranges and methods for obtaining these values within the Ansys Fluent software.
For more learning on Watertight Geometry workflow in Ansys Fluent Software
Section 2.5 – Mesh Quality Check
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Aspect Ratio: Aspect ratio in mesh quality refers to the ratio of the longest edge to the shortest edge of a mesh element.
Skewness: Skewness in mesh quality refers to the deviation of a mesh element from an ideal shape. For example, in a 2D mesh, an ideal shape might be an equilateral triangle or a square.
Orthogonality: Orthogonality in mesh quality refers to the measure of how perpendicular the mesh elements are to each other.
Skewness of 0.00
Skewness near 1.00
Skewness of 0.50
Aspect Ratio of 1.00
Aspect Ratio >> 1
A
B
A = B
A >> B
A
B
Orthogonality of 1.00
Centroid to Centroid
‘ ’
Vector Perpendicular to shared cell face aligns with Centroid to Centroid line
Section 2.5 – Mesh Quality Check
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Orthogonality | Range |
Excellent | 0.95 - 1.00 |
Very Good | 0.70 - 0.95 |
Good | 0.20 - 0.70 |
Poor | 0.10 - 0.20 |
Very Poor | 0.00 - 0.10 |
Skewness | Range |
Excellent | 0.00 - 0.25 |
Very Good | 0.25 - 0.50 |
Good | 0.50 - 0.80 |
Poor | 0.80 - 0.95 |
Very Poor | 0.95 - 1.00 |
Aspect Ratio | Range |
Excellent | 1 - 3 |
Very Good | 3 - 5 |
Good | 5 - 10 |
Acceptable | 10 - 20 |
Very Poor | > 20 |
Aspect Ratio: Aspect ratio in mesh quality refers to the ratio of the longest edge to the shortest edge of a mesh element.
Skewness: Skewness in mesh quality refers to the deviation of a mesh element from an ideal shape. For example, in a 2D mesh, an ideal shape might be an equilateral triangle or a square.
Orthogonality: Orthogonality in mesh quality refers to the measure of how perpendicular the mesh elements are to each other.
Section 2.5 – Mesh Quality Check
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Having established the criteria for a high-quality mesh, it is crucial to evaluate whether our mesh will accurately represent the underlying physics of the problem.
A thorough evaluation extends beyond simply examining quality metrics shown in the ‘console’.
So, in this section, you'll master the diagnostic tools in the Ansys Fluent tool that reveal the true quality of your mesh. We'll show you how to identify problematic elements and visualize exactly where they're located, empowering you to make informed decisions about mesh refinement. By learning these inspection techniques, you'll develop the critical skills to spot potential issues before they affect your simulation results and take precise corrective action only where necessary.
Since ‘Meshing’ is an art in itself, we recommend enrolling in the ‘Watertight Geometry Meshing in Ansys Fluent’ course for a deeper understanding of Ansys meshing tools.
Section 2.5 – Mesh Quality Check
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As the first step, let's gather all mesh quality values for both the surface and volume mesh.
Surface mesh is usually inspected by looking at ‘skewness’. Previously, we collected this value from the console as 0.47.
The Surface Mesh will affect the Volume mesh as this elements propagate into the volume mesh. Meaning abrupt size transitions or highly skewed elements will generate low quality 3D mesh elements. Directly impacting the initial boundary of your volume mesh.
A perfect orthogonality means the angle between the line connecting cell centers and the face normal vector are parallel and therefore the reason we want to check for good skewness in the surface mesh.
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
There are two built in tools to collect data from the mesh quality and they can be found in the ribbon at the ‘Mesh’ sections:
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Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
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Let's collect the ‘console’ data by clicking the arrow within ‘Check’ and click on ‘Perform Diagnostic Summary’
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Check and Collect Mesh Quality Metrics from the ‘console’ on ‘Volume Diagnostics’
a
b
Check
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
From the values provided, we conclude:
Output
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
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Now, let's collect the ‘window’ data by clicking the arrow within ‘Quality’ and click on ‘Diagnostic Tools’
In comparison to previous tools, in this one we have the authority to pick which metric is displayed within the ‘window’.
Default measure is ‘Orthogonal’
Even though ‘Orthogonal’ quality has been proved to be ‘Good’ before let’s inspect where the ‘Minimum’ values are located
b
a
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
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Close ‘Diagnostic Tool’, and in this case click on ‘Evaluate Volume Quality’
b
a
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
Output
This tool will provide: Maximum, Average and Minimum (poorest) Orthogonality.
For this case, the ‘console’ provides a list of 2 values: (0.61035289, 0.66035289). This are the elements with the poorest ‘Orthogonality’ in the mesh, and they are displayed in the window as Shown.
From this we conclude:
Section 2.5 – Mesh Quality Check
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Now, we need to collect the Volume Mesh Quality metrics by following these steps.
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Let’s go back to ‘Diagnostic tool’ and set the Measure as ‘Aspect Ratio’ for inspection and click ‘Draw’
b
a
d
c
e
‘window’ Output
‘console’ Output
End
Section 2.5 – Mesh Quality Check
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Test: Find the location of mesh elements ranging
AR = (10-11.6343)
Hint: ‘Display’ → ‘Grid’ → ‘Select Quality’ → Metric?
Now, we need to collect the Volume Mesh Quality metrics by following these steps.
The ‘Histogram’ tool will provide:
A Quality (Aspect Ratio) vs Cell Numbers
From this graph we can see that a low number of elements exceed the 10 Aspect Ratio Mark. Which is ‘good’.
From the ‘console’ Output we can see that our mesh elements average an Aspect Ratio of 5.0759569 as we wanted
From this we conclude:
‘window’ Output
‘console’ Output
Section 2.5 – Mesh Quality Check
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After checking our Mesh, and confirm we are ready to continue. We switch to the Solver by following the steps bellow
At the ribbon in section ‘Solution’, Click ‘Switch to Solution’
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CFD
Confirm the Switch by Clicking ‘Yes’
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Section 2.6 – Switch to Solver
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Successful Solver Launch
Section 2.6 – Switch to Solver
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A Transient Simulation will be used in this case since we will be studying the pulsatile nature of blood flow driven by cardiac cycles.
Boundary conditions are mathematical constraints applied at the of the computational domain to define how the flow behaves at these boundaries. Boundaries which we previously gave names (‘wall.1’, ‘wall.2’, ‘stenosis’, ‘inlet’ and ‘outlet’)
Section 2.7 – Boundary Conditions Specifications
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Section 2.8 – Viscous Model & Fluid Properties
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→ Laminar flow (since Re < 2300 for pipe flow)
Since flow continuity applies, velocity increases as the cross-sectional area decreases:
→ Laminar flow (since Re < 2300 for pipe flow)
Thus, the Carreau Model fits accordingly!
Section 2.9 – Flow Regime Verification
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The Carreau Model is only available for laminar flow simulations in the Ansys Fluent tool, and this is because the model was developed specifically to capture the non-Newtonian, shear-thinning behavior of blood under low-to-moderate shear rates characteristics of laminar flow (Bodnar, Sequeira & Prosi, 2011). Whereas for turbulent flows, the dominant energy dissipation mechanism shift from viscous effects to eddy formation and dissipation, where non-Newtonian effects become less significant as high shear rates cause blood to behave more like a Newtonian fluid. But why?
a
Section 2.10 – Viscous Model & Fluid Properties 2
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Rouleaux Formation–to–Streamlining of Red Blood Cells
From Low–to–High Shear Rates
Velocity
-
+
Blood
Flow
High
Viscosity
Low
Viscosity
Rouleaux
Structure
Breakdown of Rouleaux
Streamlining
Section 2.10 – Viscous Model & Fluid Properties 2
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In the ‘General’ Task Page. Set the ‘Time’ to ‘Transient’
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Set the Viscous Model to Laminar by going on the ‘Setup’ tree and Click ‘Models’, ‘Viscous’, and ‘Laminar’ → ‘Ok’
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a
b
c
Section 2.11 – Time & Viscous Model
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Set the Material Properties by going on the ‘Setup’ tree and Click ‘Materials’, ‘Fluid ’, ‘air’ and follow the steps:
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b
c
d
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f
g
Section 2.12 – Fluid Properties
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Set the Boundary Conditions by going on the ‘Setup’ tree and Click ‘Boundary Conditions’: Inlet(‘inlet’)
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At the ‘Velocity Inlet’, Click the arrow at ‘Velocity Magnitude’ and select ‘expression and Click ‘f (x)’
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a
b
Section 2.13 – Boundary Conditions
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Copy and paste the function given within the yellow window as shown below. Refresh and Check the values are correct by setting a Min and Max, You can start with 0 [s] and 2 [s].
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IF(mod({t},0.8[s])<=0.218[s], 0.5[m/s]*sin(4*PI*(mod({t},0.8[s])/1[s]+0.0160236)), 0.1[m/s])
Copy and Paste
a
b
c
Expression written by:
Chiyu Jiang, Cornell University
A
Modifications:
Cardiac Cycle Duration: 0.5 s → 0.8 s
UDF → Expression
Section 2.13 – Boundary Conditions
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IF(mod({t},0.8[s])<=0.218[s], 0.5[m/s]*sin(4*PI*(mod({t},0.8[s])/1[s]+0.0160236)), 0.1[m/s])
Cardiac Cycle Definition: Total cycle duration: 0.8 seconds (75 BPM)
Flow Velocity Components: During systole: Sinusoidal waveform with 0.5 m/s peak velocity
Mathematical Structure
Section 2.14 – Velocity Inlet Expression Explained
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Set the Boundary Conditions by going on the ‘Setup’ tree and Click ‘Boundary Conditions’: Outlet(‘outlet’)
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a
b
Section 2.15 – Boundary Conditions 2
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Set the Boundary Conditions by going on the ‘Setup’ tree and Click ‘Boundary Conditions’: Wall(‘wall.1’, ‘stenosis’ and ‘wall.2’)
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c
Check both ‘wall.1’ and ‘wall.2’ for ‘No Slip’ Shear Condition
a
b
Section 2.15 – Boundary Conditions 2
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Set the Boundary Conditions by going on the ‘Setup’ tree and Click ‘Solution’, ‘Initialization’. The Task Page will change, and select ‘Hybrid Initialization’ and Click ‘Initialize’
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a
b
c
Hybrid Initialization provides a better starting point for complex flows, solving potential flow equations to create ‘more realistic’ initial values with respect to the geometry. Accounting for flow acceleration at stenosed, etc.
Section 2.16 – Initialization
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Now, we will create a XY-plane for the Post processing to inspect velocity contour mid plane
In ‘Setup’, Go to ‘Results’, and Right Click ‘Surfaces’, ‘New’ and Click on ‘Plane…’
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Select ‘Method’ as ‘XY Plane’, and Click ‘Create’
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a
b
c
a
b
Section 2.17 – Surfaces & Graphics
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To generate the Velocity Contour, follow the steps:
In ‘Setup’, Go to ‘Results’, ‘Graphics’, and Click ‘Contours’, and follow ‘Change:’ steps:
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a
Change:
b
c
f
g
e
d
Section 2.17 – Surfaces & Graphics
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Since we made our simulation in Transient, we want to generate an animation of the calculations for the 2 sec specified
In ‘Setup’, Go to ‘Solution’, ‘Calculation Activities’, and Click ‘Solution Animations’, and follow ‘Change:’ steps:
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a
Change:
b
d
e
c
‘Preview’ shown in next slide
Section 2.18 – Animations
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Preview of Animation
Section 2.18 – Animations
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Change:
Now, we will create a XY-Plot for the Post processing to inspect Axial Static Pressure along x
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a
In ‘Setup’, Go to ‘Solution’ at the Ribbon. Click on ‘Plot’, and follow ‘Change:’ steps:
f
f
b
c
d
e
Section 2.19 – Plots
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Set the Boundary Conditions by going on the ‘Setup’ tree and Click ‘Solution’, ‘Run Calculation’. The Task Page will change, and
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a
As we selected ‘Transient’ in ‘Time’. We are required to specify the number of Time Steps and its respective Size.
b
c
Section 2.20 – Run Calculations
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Solution Converged ✔
Successful Simulation/Calculations
Section 2.20 – Run Calculations
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Check the animation by going to ‘Setup’, ‘Results’, ‘Animations’ and Click on ‘Playback’. Select the ‘Animation Sequence’ and Click the play button
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a
b
c
Section 2.21 – Animation Playback
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Check the Animation!
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Section 2.21 – Animation Playback
You can find the animation in Slide 82!
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Check the Report!
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End
Section 2.22 – Report Plot
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/ Make a similar animation for Wall Shear Stress Contour vs Flow time
Wall Shear Stresses
Which is the tangential force exerted by blood on the vessel walls. Clinically, this may lead to rupture of the fibrous cap if mechanical stresses are large enough. Releasing plaque material and blood clots into the bloodstream in the case of atherosclerosis which may lead to heart attacks or strokes.
Notice any different Surfaces used?
Tip: To collect data for an animation that was not generated before running the calculations, you need to reinitialize the model and rerun the simulation after setting up the contour and animation.
Section 2.23 – Homework
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Velocity Contour
The post-stenotic low-velocity region (depicted in blue) develops, and this region expands as the severity of the stenosis increases. In this area, mass transport is weak, and wall shear stress (WSS) is low, creating conditions that are highly prone to thrombosis in clinical settings. (Zhou, Lee & Wang, 2018)
The first 25 frames were used on the left, this accounts for the first
Of which the first 0.218 sec are the Systolic Phase.
Frame: 25
Frame: 1
Frame: 20
Frame: 15
Frame: 10
Frame: 5
Section 3 – Results
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Section 3 – Results
Real–Time: 2 sec
Slowed by x4
Video–Time: 10 sec
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Pressure @ Outlet Overtime
Section 3 – Results
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Pressure @ Outlet Overtime
This plot shows the area-weighted average of absolute pressure at the outlet of your stenosed vessel over time, measuring approximately 111,990 Pa. This represents the combination of atmospheric pressure (101,325 Pa) and the specified outlet gauge pressure condition (10,666 Pa, equivalent to about 80 mmHg).
Key observations show:
Section 3 – Results
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