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Cardiovascular Fluid Mechanics

National Biomechanics Day

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What is a fluid?

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Fluid:

A material that continuously deforms under applied shear stress

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Fluid mechanics is the study of fluids in…

motion (fluid dynamics)

at rest (fluid statics)

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Why do we study fluid dynamics?

  1. Understand fluid flow (velocity, pressure)
  1. Understand how influences objects (forces, energy)

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Why do we care about fluids in our body?

=

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But… these equations are very difficult to solve for complex problems!

We use the Navier-Stokes Equations* to describe the behavior of any fluid

*One of the seven Millennium Prize Problems:

https://www.claymath.org/millennium-problems/navier–stokes-equation

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However, we can solve these equations for some simple problems!

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Simple example 1: Poiseuille flow

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Simple example 1: Poiseuille flow

Using Navier-Stokes, we can predict that…

What does the velocity change throughout the pipe

How much pressure do we need to push this water?

R

L

Q: Flow rate [ml/s]

Velocity u(r)

r

p1

p2

[Pa]

[m/s]

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Simple example 2: Mass conservation

Q1 [m3/s]

Q2

The flow rate does not change, but velocity does!

A1

A2

V1 [m/s]

V2

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Simple example 3: Bernoulli’s Principle

Bernoulli’s Principle tells us how energy (velocity, pressure) changes throughout the fluid

Region 1

Region 2

V1

V2

p1

p2

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Going from simple fluid dynamics problems to complex ones

In complex blood vessels, we cannot :(

In a straight pipe, we can find a simple equation!

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What do we do for complex problems, like the human body?

We have to solve these equations with computational fluid dynamics!

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Coronary artery disease

p1

p1

p2

p1

p2

p2

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Aortic valve stenosis

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Aortic valve stenosis

Measuring pressure inside someone’s heart is hard!

p1

p2

p1

p2

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Application of Bernoulli’s Principle

Echocardiography uses sound waves to create images of our heart and to measure blood velocity (Doppler effect)

We can measure v1,v2 !

P1

P2