1 of 82

Presentations Shopping Cart

Please make a copy of the cart and

follow the instructions on next slide

Prepared by Patrick Capon and Christina Hall

Contact: comms@biocommons.org.au

Last updated 4 December 2024

2 of 82

Instructions

  • The cart is a collection of frequently presented slides, sorted by category
  • It is designed for you to pick out and use slides in your presentations
  • Each slide comes with suggested audience(s) and speaker notes
  • Slides will be kept up to date by the comms team

Actions

  • Make a copy of the slides you want and edit them for your audience and messaging
  • Adjust your slide deck theme as per the guidelines
  • Let the comms team know if you need further assistance or changes

3 of 82

Quick navigation

The bare minimum: BioCommons in two slides

Introductory slides (scene setting, housekeeping)

Strategy slides (national context, purpose, vision, mission)

How we work (values, core practice, collaboration principles, organisational design)

Closing/outro slides

Content slides (what we do, what we offer, how we engage)

BioCommons services (one slide per service)

BioCommons activities (one slide per activity)

4 of 82

BioCommons in�two slides

5 of 82

Australian BioCommons enables the analysis of life science data through national research infrastructure: digital techniques, data and tools

Streamlines access to national scale analysis and data services

  • Galaxy Australia
  • Australian Apollo Service
  • Australian AlphaFold Service
  • Australian Fgenesh++ Service
  • Australian Nextflow Seqera Service
  • Australian BioCommons Leadership Share
  • Bioinformatics ToolFinder
  • Bioinformatics WorkflowFinder
  • Bioplatforms Australia Data Portal
  • Training Infrastructure as a Service

Offers national scale strategic advice and leadership

Convenes communities

of practice

Develops and maintains community scale digital infrastructure in concert with international peers

Delivers a national

training program

6 of 82

Connecting with Australian BioCommons

Want to learn a new skill?

Participate in an online workshop or watch a webinar recording: biocommons.org.au/webinars-workshops

Looking for events, jobs, training opportunities and news?

Subscribe to the BioCommons monthly e-news: biocommons.org.au/news

Want to help design relevant bioinformatics infrastructure and services?

Join a researcher community that convenes around your methodology: biocommons.org.au/domains

Interested in delivering training?

Collaborate via the National Bioinformatics Training Cooperative: biocommons.org.au/trainingcooperative

@ausbiocommons.bsky.social

biocommons.org.au

AustralianBioCommons

AustralianBioCommonsChannel

7 of 82

Housekeeping slides

8 of 82

Acknowledgement of Country

We acknowledge the Traditional Owners and their custodianship of the lands on which we meet today.

We pay our respects to their Ancestors and their descendants, who continue cultural and spiritual connections to Country.

We recognise their valuable contributions to Australian and global society.

9 of 82

Enhancing analysis of life science data by providing national scale research infrastructure

biocommons.org.au/subscribe

Follow us on:

10 of 82

Housekeeping

Session is recorded

Autogenerated captions available

Questions via Q&A function

11 of 82

Strategy slides

Slides regarding what we do, funding,�our vision, mission, collaboration principles, values

12 of 82

National Context

Provides strategic funding for national-scale research infrastructure – driving collaboration to bring economic, environmental, health and social benefits for Australia.

13 of 82

National Context

Provides strategic funding for national-scale research infrastructure – driving collaboration to bring economic, environmental, health and social benefits for Australia.

Supports Australian life sciences research by investing in state-of-the-art research infrastructure in genomics, proteomics, metabolomics, synthetic biology and bioinformatics.

14 of 82

National Context

Supports Australian life sciences research by investing in state-of-the-art research infrastructure in genomics, proteomics, metabolomics, synthetic biology and bioinformatics.

Provides strategic funding for national-scale research infrastructure – driving collaboration to bring economic, environmental, health and social benefits for Australia.

Bioplatforms Australia identified that omics is a major contributor to data-centric digital sciences and demands investment in computing power, data management, software development and deployment, and in expertise not traditionally identified with the biological sciences. ��Australian BioCommons represents Bioplatforms Australia’s response to this digital transition

15 of 82

Australia’s 25 National Research Infrastructures

Physics & Astronomy

Marine

Imaging

Earth & Environment

Human

Biology

Compute, access, data

16 of 82

NCRIS funding via Bioplatforms Australia has established Australian BioCommons,

which provides fully subsidised bioinformatics infrastructure designed to support collaborative omics focused life science research in Australia.

17 of 82

Underpinning arrangements

Governance

The scope, purpose and activities of Australian BioCommons are defined in funding agreements between the Commonwealth Department of Education and Bioplatforms Australia. ��The Board of Bioplatforms Australia has overall governance accountability. �

Legal

Australian BioCommons is not a legal entity. It is established through a contract between Bioplatforms Australia Ltd. and the University of Melbourne. The University of Melbourne executes contracts with organisations participating or contributing to Australian BioCommons activities. �

Delivery

The University of Melbourne is accountable to Bioplatforms Australia for the successful delivery of Australian BioCommons. The performance of Australian BioCommons is monitored and reported annually.

18 of 82

Australian BioCommons’ purpose

Enable Australian life sciences researchers and their collaborators to:

  • Understand the molecular basis of life by applying advanced digital research infrastructure, tools, software and training

  • Access and apply the bioinformatics tools, methods and reference data that can address national challenges and research questions.

19 of 82

Australian BioCommons’ vision

Australia's life science research and research translation is enhanced through world class collaborative distributed bioinformatics infrastructure.

World class bioinformatics capabilities empower breakthrough discoveries enabling the realisation of Australia's ambitions in human health, agriculture and biodiversity.

20 of 82

Australian BioCommons enables the analysis of life science data through national research infrastructure: digital techniques, data and tools

Streamlines access to fully-subsidised, national scale analysis and data services

Offers strategic advice and leadership at a national scale

Convenes communities

of practice

Develops and maintains community scale digital infrastructure in concert with international peer infrastructures

Delivers a national

training program

21 of 82

Mission

  • Sustain strategic leadership in the provision and use of bioinformatics and bioscience data infrastructures at a national scale
  • Actively support life science research communities with community-scale digital infrastructure, developed and maintained in concert with international peer infrastructures, and tailored to support bioinformatics practice
  • Deliver sophisticated analysis capabilities, including software and hardware platforms that underpin world class science
  • Support digital asset stewardship and management, retention, integration and publication solutions as they evolve

22 of 82

Mission

  • Provide access to the digital techniques, data and tools that advance Australian capabilities in human, agricultural, and environmental genomics through omics research and its translation
  • Accelerate and enhance the impact of bioinformatics by leveraging digital technology advances such as artificial intelligence to significantly lift the productivity and capability of both intensive and occasional users of bioinformatics
  • Provide training and support solutions that develop transferable digital research and bioinformatics skills to leverage platforms, tools, services and techniques.

23 of 82

33,000 researchers

(i.e. ~ ⅓ of Australian publicly funded researchers)

+200,000 students

24 of 82

Focus areas

50%

15,000

30%

9,000

20%

6,000

25 of 82

Closing slides

26 of 82

Take home messages

  • We operate multiple mature and robust services that will support your work
  • All experience levels are catered for
  • Our teams will work to help get you up and running
  • We can collaborate with your team to get the most out of these services
  • We encourage you to join our community activities
  • We welcome your input regarding further shared community-scale�national infrastructure that is required

27 of 82

Connecting with Australian BioCommons

Want to learn a new skill?

Participate in an online workshop or watch a webinar recording: biocommons.org.au/webinars-workshops

Looking for events, jobs, training opportunities and news?

Subscribe to the BioCommons monthly e-news: biocommons.org.au/news

Want to help design relevant bioinformatics infrastructure and services?

Join a researcher community that convenes around your methodology: biocommons.org.au/domains

Interested in delivering training?

Collaborate via the National Bioinformatics Training Cooperative: biocommons.org.au/trainingcooperative

@ausbiocommons.bsky.social

biocommons.org.au

AustralianBioCommons

AustralianBioCommonsChannel

28 of 82

Keep in touch

Subscribe to the BioCommons monthly e-news: biocommons.org.au/news

Upcoming webinars and workshops: biocommons.org.au/webinars-workshops

@ausbiocommons.bsky.social

biocommons.org.au

AustralianBioCommons

AustralianBioCommonsChannel

29 of 82

Thanks for joining us!

Australian BioCommons is enabled by NCRIS via Bioplatforms Australia funding

30 of 82

How we work slides

Values, organisational design

31 of 82

Key characteristics of Australian BioCommons

Simple to use service platforms

Support different expertise levels

Technical platforms for programmatic access

Skills development

Support for all of life science

Global participation

32 of 82

Values

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

33 of 82

Values

We welcome and value the full range of experiences, strengths and opinions.

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

34 of 82

Values

We are honest, committed and accountable, and can be trusted to meet high standards.

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

35 of 82

Values

We nurture relationships to underpin and encourage collaboration at every level of operation.

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

36 of 82

Values

We actively listen and integrate many voices to clarify shared visions. We build reputation and demonstrate value through how we engage and communicate.

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

37 of 82

Values

We strive for continuous improvement, show initiative, pre-empt needs and implement best practices.

Respect

Collaboration

Integrity

Communication

Innovation

Our values underpin the work we do, and how we do it:

38 of 82

Core practice

Infrastructure

Training

Services

39 of 82

Collaboration principles

Start with national intent

Partner internationally to contribute to and benefit from larger efforts

Unburden researchers from infrastructure management

Identify and work with

community champions

Partner locally to deliver maximum impact to life scientists

Empower staff, collaborator and user’s ambitions

40 of 82

Collaboration principles

Start with national intent

Unburden researchers from infrastructure management

Identify and work with

community champions

Empower staff, collaborator and user’s ambitions

  • Align our activities with the vision and mission of Bioplatforms Australia and actively support Bioplatforms Australia’s scientific initiatives and collaborations��
  • Prioritise activities that: �benefit the ambitions expressed by national research communities and, �engages with participants already addressing national outcomes or that are willing to support their achievement

Partner internationally to contribute to and benefit from larger efforts

Partner locally to deliver maximum impact to life scientists

41 of 82

Collaboration principles

Partner internationally to contribute to and benefit from larger efforts

Start with national intent

Unburden researchers from infrastructure management

Identify and work with

community champions

Empower staff, collaborator and user’s ambitions

Partner locally to deliver maximum impact to life scientists

  • A sustained global wave of investment is continuing into bioinformatics infrastructure�
  • Australian BioCommons intends to participate in and contribute to larger critical mass efforts, to reuse and improve rather than build anew, and to ‘ride (and actively contribute to) that wave’�
  • This intent reflects a desire to gain the maximum benefit possible from large global investments to address the bioinformatics challenges present in life science research

42 of 82

Collaboration principles

Unburden researchers from infrastructure management

Identify and work with

community champions

Partner locally to deliver maximum impact to life scientists

Start with national intent

Partner internationally to contribute to and benefit from larger efforts

Empower staff, collaborator and user’s ambitions

  • Australian BioCommons is funded to enable national bioinformatics research infrastructure but cannot support the required nationwide scale of use on its own.
  • We partner with other NCRIS national digital research infrastructures, state and institutional level bioinformatics centres of expertise and institutional digital infrastructures to provide life science researchers with bioinformatics support, compute and data capacity.
  • Partnering with BioCommons provides a means for those digital infrastructure capabilities to enhance their impact in the life sciences.

43 of 82

Collaboration principles

Start with national intent

Partner internationally to contribute to and benefit from larger efforts

Partner locally to deliver maximum impact to life scientists

  • A key part of Australian BioCommons’ mission is to actively support life science research communities with community-scale digital infrastructure.
  • That requires input from champions: community members with a significant level of experience and awareness of national and international initiatives and approaches.
  • Australian BioCommons aims to work with champions within these communities that have that expertise.
  • These may be champions for bioinformatics techniques or their scientific application, and in infrastructure development and supply.

Unburden researchers from infrastructure management

Identify and work with

community champions

Empower staff, collaborator and user’s ambitions

44 of 82

Collaboration principles

Start with national intent

Partner internationally to contribute to and benefit from larger efforts

Partner locally to deliver maximum impact to life scientists

  • Best practice bioinformatics methods constantly evolve, as do the underlying infrastructure requirements. �

Australian BioCommons supports a software and expertise capability that tailors infrastructure for bioinformatics use, allowing researchers to focus on method development and dissemination rather than infrastructure management.

Unburden researchers from infrastructure management

Identify and work with

community champions

Empower staff, collaborator and user’s ambitions

45 of 82

Collaboration principles

Start with national intent

Partner internationally to contribute to and benefit from larger efforts

Partner locally to deliver maximum impact to life scientists

  • Australian BioCommons develops the talents and aspirations of its staff, collaborators and users. ��This principle encodes a core tenet of the Australian BioCommons team.

Unburden researchers from infrastructure management

Identify and work with

community champions

Empower staff, collaborator and user’s ambitions

46 of 82

Structure

  • Three layers
  • A primary goal of Australian BioCommons is to achieve a cohesive result across several hundred people sourced on a full time or fractional basis from many different organisations.

Executive

Coordination Hub

Participants

Director, A/Directors

Hub Team

47 of 82

Divisions

Six divisions, each headed by an executive team member.

Each has accountability for the strategic direction, stakeholder management, resourcing and delivery of the activities, infrastructure and/or services in their area of expertise.�

Leadership, Management and Operations

Engagement & Community Response

Platforms and Services

Human Genome Informatics

Training and Communications

BioCloud

48 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

49 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

50 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Delivery partners ��Support long term roles required to support BioCommons activities and/or long term access to requisite infrastructure and services.�e.g. NCI, Pawsey, AARNet, QCIF

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

51 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Project participants ��Engage in focused projects for a fixed term and provide personnel and infrastructure resources as agreed in a project plan.

e.g. Garvan, QIMRB, etc

Delivery partners ��Support long term roles required to support BioCommons activities and/or long term access to requisite infrastructure and services.�e.g. NCI, Pawsey, AARNet, QCIF

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

52 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Technology developers ��Our co-development principle leads to the use of internationally sourced research infrastructure technologies and systems.

e.g. Galaxy, Gen3

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

Project participants ��Engage in focused projects for a fixed term and provide personnel and infrastructure resources as agreed in a project plan.

e.g. Garvan, QIMRB, etc

Delivery partners ��Support long term roles required to support BioCommons activities and/or long term access to requisite infrastructure and services.�e.g. NCI, Pawsey, AARNet, QCIF

53 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Service suppliers��A number of fee-for-service suppliers provide specific software licences, expertise and/or pay as you go infrastructure to Australian BioCommons.

e.g. Seqera, Softberry, AWS

Technology developers ��Our co-development principle leads to the use of internationally sourced research infrastructure technologies and systems.

e.g. Galaxy, Gen3

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

Project participants ��Engage in focused projects for a fixed term and provide personnel and infrastructure resources as agreed in a project plan.

e.g. Garvan, QIMRB, etc

Delivery partners ��Support long term roles required to support BioCommons activities and/or long term access to requisite infrastructure and services.�e.g. NCI, Pawsey, AARNet, QCIF

54 of 82

Participants

Australian BioCommons strategy hinges on the enlistment of many contributors that engage with their

own resources.

Community contributors ��Voluntarily assist in the National Bioinformatics Training Co-op and actively participate in researcher consultations and community meetings

(of which there are many)

Service suppliers��A number of fee-for-service suppliers provide specific software licences, expertise and/or pay as you go infrastructure to Australian BioCommons.

e.g. Seqera, Softberry, AWS

Technology developers ��Our co-development principle leads to the use of internationally sourced research infrastructure technologies and systems.

e.g. Galaxy, Gen3

Nodes ���Employ staff who have key roles within BioCommons leadership, coordination and Hub teams.�UoM, USyd, QCIF

Project participants ��Engage in focused projects for a fixed term and provide personnel and infrastructure resources as agreed in a project plan.

e.g. Garvan, QIMRB, etc

Delivery partners ��Support long term roles required to support BioCommons activities and/or long term access to requisite infrastructure and services.�e.g. NCI, Pawsey, AARNet, QCIF

55 of 82

Content slides

Slides regarding what we do, what we offer, how we engage

56 of 82

Australian BioCommons services and training are fully subsidised for Australian researchers and students to use

Service delivery partners

  • Galaxy Australia
  • Australian Apollo Service
  • Australian AlphaFold Service
  • Australian Reference Genome Atlas
  • Bioinformatics Tool Finder
  • Bioinformatics Workflow Finder
  • Bioplatforms Australia Data Portal
  • Australian BioCommons Leadership Share (ABLeS)
  • Australian Fgenesh++ Service
  • Australian Nextflow Seqera Service

Web accessible

Command

line

  • Webinars
  • Hands-on workshops events
  • Training Infrastructure as a Service

Training

57 of 82

Engagement with research organisations

PLANT PROTEIN ATLAS

AUSTRALASIA

58 of 82

BioCommons engages with:

single cell omics

multi-omics

genomics

microbiome analysis

proteomics

metabolomics

Methods based communities

Research�consortia

Data production facilities

59 of 82

BioCommons facilitates interactions with computational providers to build a fit-for-purpose, flexible and cohesive data analysis ecosystem

bioinformaticians

core �facilities

life scientists

60 of 82

BioCommons facilitates interactions with computational providers to build a fit-for-purpose, flexible and cohesive data analysis ecosystem

Methods base communities

Research consortia

Data production facilities

single cell omics

multi-omics

genomics

microbiome analysis

proteomics

metabolomics

61 of 82

BioCommons identifies and documents needs

SURVEY

genome annotation

comparative�genomics

genome assembly

metagenomics

proteomics

etc...

Genome Assembly Infrastructure Roadmap for Australia

V4.0

July 2020

Genome Annotation Infrastructure Roadmap for Australia

V4.0

July 2020

Comparative Genomics Infrastructure Roadmap for Australia

V4.0

September 2022

62 of 82

Then deploys services for all to use

BIOINFORMATICS �TRAINING

63 of 82

Engagement is cyclic and ongoing

Infrastructure

Training

Services

64 of 82

BioCommons training program

  • Diverse, high quality training events
  • Accessible and free to all Australian life scientists
  • Helping researchers keep up with the latest in bioinformatics
  • Past webinars available on the BioCommons YouTube Channel

biocommons.org.au/webinars-workshops

65 of 82

National Bioinformatics Training Cooperative

~25 events per year

200+ Trainers

66 of 82

Outreach and communications

  • Over 2,000 monthly newsletter subscribers
  • Rapid growth on LinkedIn
  • YouTube houses a library of recorded events
  • Receives ~2,000 new views each month
  • Keep up to date through the newsletter or online
  • Pitch a story that will benefit Australian researchers!

67 of 82

Content slides

Each service in one slide

68 of 82

  • 1500+ tools, 220+ reference data sets
  • Upload data, execute, download data
  • Drag and drop tools into workflows
  • Share workflows with collaborators
  • Powerful compute backend (AARNet, NCI,�Pawsey, Nectar Cloud, Microsoft Azure)
  • Unmetered compute (use as much as you like)
  • Extensive training material available

69 of 82

National compute network

CBR

BNE

SYD

MEL

PER

usegalaxy.org.au

70 of 82

Bioplatforms Australia Data Portal

  • Free to browse and search for data using a web-based interface or programmatically
  • Data from all Bioplatforms Framework Initiatives is available
  • A minimum metadata standard (incorporating internationally agreed standards) is required to describe samples and data files�

71 of 82

Australian Apollo Service

  • Apollo - a JBrowse based system to enable collaborative, manual correction of automated genome annotations
  • Apollo Service: the set-up and management of the underlying IT is taken care of
  • Fully subsidised for Australian researchers
  • Just sign up and start using it (upload your genome and evidence files)

72 of 82

Australian Nextflow Seqera Service

  • Nextflow: an emerging standard to define bioinformatics workflows
  • A centralised ‘command post’ to run and monitor the execution of Nextflow pipelines on your compute infrastructure
  • Web interface and API available
  • Enabled through a national licence with Seqera Labs

73 of 82

Australian Nextflow Seqera Service - three in one

Personal Workspace

Organisation Workspace

Analysis Service

74 of 82

Australian Alphafold Service

  • An AI system that predicts a protein’s structure from its sequence
  • Available for use via Galaxy Australia, which provides the underlying compute power and set up needed to run Alphafold
  • Fully subsidised for Australian researchers
  • Register for access via Galaxy Australia

75 of 82

  • A one-stop shop for finding genomic data for Australian species
  • Genomes, barcodes, raw and assembled data
  • Data from NCBI, BPA Data Portal, BOLD (with more to come)

76 of 82

Australian BioCommons Leadership�Share (ABLeS)

  • Computational resource, specialist expertise, and shared bioinformatics tools at NCI and Pawsey
  • Allocations for reference data asset generation, production analyses, and the Software Accelerator
  • No need to apply through NCMAS or other merit allocation schemes for HPC access
  • Open to all Australian researchers and research organisations

77 of 82

Australian Fgenesh++ Service

  • Commercial automatic genome annotation software which predicts genes in eukaryotic genomes
  • Fully subsidised for Australian-based researchers
  • Accessible via command-line or on�Galaxy Australia

78 of 82

Finder Services

ToolFinder

  • Find bioinformatics tools and software installed across our infrastructure partners’ systems

Workflow Finder

  • Browse workflows registered by our partners on WorkflowHub

Discover

Evaluate

Reuse

79 of 82

Content slides

Each activity in one slide

80 of 82

BioCLI project

Focus on:

  • Accessibility and usability
  • Tailored computational resources
  • Performance and scale

Empowering life scientists with user-focused CLI environments and services

Preconfigured & portable virtual machine image with essential bioinformatics tools, libraries, and datasets.

Expand access to GPU-accelerated tools like Alphafold by enabling connections to GPU hardware and conversion of hardware-specific libraries.

Enable researchers to build, deploy, and scale community-supported workflows on the computational infrastructures they use.

81 of 82

Workflow Commons

Keeping up with the rapid evolution of omics data methods!

Focus on the ‘glue’ that holds everything together:

  • Workflows
  • Services
  • Training
  • Documentation
  • Collections & standards

Workflow �infrastructure

Workflow �developers

Workflows �community

Workflow �Commons

Workflow �users

82 of 82

Australian Cardiovascular disease Data Commons

  • Large collaboration led by Baker Heart & Diabetes Institute
  • Built with Gen3 technology
  • Runs on Amazon AWS
  • Will contain pooled data from 400k individuals across 18 cohorts