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Generating & Executing an Individual Action Plan to Achieve Excellence in Clinical Trials

Karen Winkfield, MD, PhD

Executive Director, Meharry-Vanderbilt Alliance

Ingram Professor of Cancer Research

Professor of Radiation Oncology

Vanderbilt University Medical Center

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Professor of Health Policy

Meharry Medical College

DRIVE Initiative

Indianapolis, IN

March 7, 2025

#BeIntentional: ��What Question Are you trying to Answer??

Promoting Excellence in Clinical Research

13 studies (nine in academic and four in community settings) with 8883 patients

Systematic Review and Meta-Analysis of the Magnitude of Structural, Clinical, and Physician and Patient Barriers to Cancer Clinical Trial Participation. Unger, et al. J Natl Cancer Inst. 2019 Mar; 111(3): 245–255

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https://www.fightcancer.org/policy-resources/barriers-patient-enrollment-therapeutic-clinical-trials-cancer

• How many practice sites
• Number of physicians
• Patient demographics
• Available team members

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What patients need may differ

The types of interventions available will differ

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Right-Sizing Interventions

Social Determinants of Health (SDOH)

• Beyond Health Care: The Role of Social Determinants in Promoting Health and Health Equity; 2018

How You Can Improve Clinical Trial Enrollment

Acting on the Identified Needs

#BeIntentional

Leveraging community services to enhance provision of comprehensive �health care

Your Advocacy Matters

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Thank you!!

Questions?

@DrWinkfield

@3BlackDocs

www.drkarenwinkfield.com

3blackdocs.com

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