Rank Score: Practical Applications and Utility of the DRIVE Rank Calculator in Clinical Trial Development

Maya Birhiray, MS^1,2 & Sam Ranger, MS¹

¹Indy Hematology Education, Inc., ²Indiana University School of Medicine

• Sam Ranger: IQVIA former employee (within the past two years)
• Maya Birhiray: Nothing to disclose

Disclosures/Conflicts of Interest

Ranking

Birhiray and Birhiray, 2022

Ranking

Birhiray and Birhiray, 2022

Calculator Applications in 2024

• Expanded cancer types
• Now includes 35 distinct cancers
• Conducted internal survey at Maui DRIVE Summit
• Geospatial data for greater specificity in Score calculations
• Presented at 66th ASH Annual meeting
• Included two separate publication^1,2
• Invitation to submit full manuscript

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1. Birhiray et al.
2. Ranger et al.

• Expansion of geospatial data
• Working with the University of Kentucky’s “Cancer InFocus”
• Conversations with Blood editorial board and senior director for publications at ASH
• Improving and updating demographic data reporting policies
• Submission of abstract to ASCO annual meeting
• Collaborating with the EHA to update their diversity reporting policies

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Calculator Applications for 2025

• Striving for a Score of 3 or greater
• “Clinical trial excellence”
• Using calculator to “DRIVE” enrollment goals
• Ensure data is generalizable and transportable
• Employing Score to assess clinical relevance

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Tool Utilization

Tool Utilization

Internal Validity

Clinical Relevance

Acknowledgements

We would like to extend sincere gratitude to Indy Hematology Education, Inc. for their invaluable support in the creation and presentation of this initiative. Their contributions and commitment to advancing hematology research have been instrumental in making this work possible.

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References

1. Maya Birhiray, Sam Ranger, Ruemu Birhiray; A Systematic Review of 72 ASH Plenary and Late Breaking Abstracts for Racial Representation: A Health Equity Call to Action. Blood 2024; 144 (Supplement 1): 5081. doi: https://doi.org/10.1182/blood-2024-205723
2. Maya N. Birhiray, Ruemu E. Birhiray; Practical strategies for creating diversity, equity, inclusion, and access in cancer clinical research: DRIVE. Blood Adv 2023; 7 (8): 1507–1512. doi: https://doi.org/10.1182/bloodadvances.2022008220
3. Sam Ranger, Maya Birhiray, Ruemu Birhiray; Development and Use of an Application for the Calculation of Diversity Scores of Clinical Trials: A DRIVE Score Calculator. Blood 2024; 144 (Supplement 1): 7774. doi: https://doi.org/10.1182/blood-2024-207744