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Ch 5 - Pathology

Unit Review

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1. Gain an understanding of the proper use and meanings of the various terms of Pathology

- Pathology

  • Diagnosis
  • Signs
  • Symptoms
  • Syndrome
  • Acute
  • Chronic
  • Subacute
  • Etiology
  • Idiopathic
  • Communicable
  • Pathogenesis
  • Latent
  • Incubation
  • Convalescence
  • Remission
  • Cure
  • Epidemiology
  • Endemic
  • Epidemic
  • Pandemic
  • Causal Relationship
  • Coincidental Relationship
  • Prevention
  • Therapy

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2. What are the 8 mechanisms of disease and their basic processes?

1. Genetic: altered genes → altered proteins, may not function, function improperly

 

2. Pathogenic Organisms: organisms that cause disruption, often parasitic

 

3. Tumors and Cancer: abnormal tissue growth (neoplasms)

 

4. Physical and Chemical Agents: mechanical injury, extreme temperatures, toxins, radiation

 

5. Malnutrition: improper or insufficient nutrition, lack of needed minerals and vitamins

 

6. Autoimmunity: body’s immune system attacks itself

 

7. Inflammation: swelling usually caused by other mechanisms, but the swelling itself can cause damage (extended time, extensive swelling)

 

8. Degeneration: breaking down of tissue, usually associated with aging

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3. What are the 6 risk factors and how do they contribute to disease?

  • Genetic Factors
  • Age
  • Lifestyle
  • Stress
  • Environmental Factors
  • Pre-existing Conditions

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4. Pathogenic Organisms:

Viruses- basic structures (nucleic acid/ protein coat) and mechanism

- ex. AIDS, COVID-19

Bacteria- unicellular prokaryote, know basic mechanisms

How are staining, shape, and grouping used to classify bacteria?

Be able to classify bacteria by these techniques.

Fungi- eukaryote (unicellular yeast, multicelled mycotic)- recognize examples

Protozoa- unicelled eukaryotes- mechanism, classification by method of movement

Animals- multicelled eukaryotes- usually parasitic, know 3 basic groups

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5. What are the 4 ways diseases are usually spread?

  • Person-to-Person
  • Environmental contact
  • Opportunistic infection
  • Vectors

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6. What techniques are used to prevent disease? (know both aseptic & vaccine techniques)

  • Disinfection/Sterilization/Antiseptics
  • Isolation/Quarantine
  • Hygiene & Sanitation
  • Vaccine – prevent viral infection using dead or disabled virus

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7. How do we treat and contain infection?

  • Antibiotics – bacteria
  • Antifungal – fungi
  • Toxins – Parasites
  • Anti-retroviral (limit transmission of HIV)

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8. What are the basic medical imaging techniques, and how are these various techniques used in disease diagnosis?

X-Ray – radiation and film show dense tissue

Flouroscopy & Radiopaque– chemicals glow or make organs visible on xray film

CT Scan – computer and multiple images (can be 3D)

MRI – magnets influence soft tissue, record the signals as they return to shape

Ultrasound – sound waves converted into images

Endoscope/Laparoscope - Insert camera into body

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9. Cancer:

  • benign vs. malignant
  • common cancers
  • signs of cancer
  • causes of cancer
  • pathology- diagnosis (staging/grading)
  • treatment of cancer

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10. Why and how does the inflammatory response occur?

  • The heat, redness, pain and swelling result from several factors:

Chemotaxis draws WBC → pus

Mediators increase blood flow (redness/heat)

Edema- swelling from increased fluids (lymph)

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11. What common diseases result from inflammation?

  • Systemic: Fever
  • Acute/Chronic: Asthma, Bronchitis, Arthritis, Eczema