Brain Pacer
pillar.vc Nucleate.org Aria.Org.UK
A NON-INVASIVE, ADAPTIVE BRAIN-COMPUTER INTERFACE ��for
�Sensing and Stimulation �to deliver Personalised Neurological Therapies
Team 4
Neurological diseases are circuit-disorders.
No non-invasive, real-time method to deliver patient-tailored neuromodulation to treat circuitopathies.
Stroke 93 million
Brain tumours 3.4 million
Neuropsychiatric �440 million
Movement disorders �30 million
Closed loop non invasive ultrasound BCI
Brain Pacer
Ultrasound sensing and stimulation
Targeted, adaptive, non-invasive treatment of diseased circuits
Continuously senses brain activity (fUS), detects circuit dysfunction
Responds in real time via non invasive LIFU
Closed loop - therapy tailored to each patient’s moment-to-moment brain state
Background
4
Competition
High temporal resolution
High Spatial resolution
Intracortical implants
Neuralink
Blackrock
Paradromics
fNIRS
Kernel
M/EEG
Neurable
Emotive
Bitbrain
Endovascular
Syncron
Forest Neurotech
Brain Pacer
Low Spatial resolution
Low temporal resolution
Competition
High brain coverage
Invasiveness
Intracortical implants
Neuralink
Blackrock
Paradromics
fNIRS
Kernel
M/EEG
Neurable
Emotive
Bitbrain
Endovascular
Syncron
Forest
Neurotech
Non-invasive
Low brain coverage
Brain Pacer
Patient Centred Technology
Increased clinical uptake
Bridges the translational gap
Lived experience ensures success
Improved treatment compliance
7
Non-invasive Design
Market
TAM: Total Addressable Market
“Global spend on neurological conditions”
SAM: Serviceable Available Market
“Global spend on monitoring for Parkinson’s, Addiction, and Brain cancer”
SOM: Serviceable Obtainable Market
“10% of 1.1M Parkinson’s patients in USA (DBS eligible) at a cost of $2000 per device”
$220M
$3.5B
$1.7T
pillar.vc Nucleate.org Aria.org.UK
Brain Pacer Team
Olha Dolinska
Co-Founder
Investor
Yizhou Wan
Co-Founder
Neurosurgeon
Francisca Ferreira
Co-Founder
Neurosurgeon
Pradeep D
Co-Founder
Neuroscientist
Joshua Daoud
Co-Founder
Biomedical Engineer