Michael A. Perelman, Ph.D.
Founder & Chairman
MAP Education & Research Foundation
New York, N.Y. 10075 USA
The STP Model Helps Optimize The Diagnosis & Treatment Of SD
Additional material is available for free at
MAP Education & Research Foundation’s
Website: mapedfund.org
PGY IV Presentation, 2023.03.30
© 2023 MAP Education & Research Foundation
The STP Model Helps Optimize �The Diagnosis & Treatment Of SD
© 2023 MAP Education & Research Foundation
AGENDA
© 2018 MAP Education & Research Foundation
Perelman MA. J Sex Med. 2006; 3:1004-1012;
Perelman MA. J Sex Med, 2009;6(3):629-32.
The STP Model Helps Optimize The
Diagnosis & Treatment Of SD
Why?
�����
Adapted from Rosen, CIEF
Because sexual response is best understood as an endpoint, representing the cumulative interaction of every cognitive, behavioral, social and cultural factor, not merely the biomedical or “physical” determinants!
© 2018 MAP Education & Research Foundation
The Sexual Tipping Point, Illustrates All �The Intra And Interindividual Variability, �Characterizing Sexual Disorders’ Etiology, Diagnosis And Treatment
© 2018 MAP Education & Research Foundation
Inhibition
Excitation
Insipient Metabolic Syndrome
© 2018 MAP Education & Research Foundation
THE SMALL CIRCLES IN THE MENTAL & PHYSICAL “CONTAINERS”
ON THE SEXUAL BALANCE BEAM, SYMBOLIZE ALL THE MULTITUDE OF FACTORS THAT DETERMINE SEXUAL RESPONSE. THEY FUNCTION AS DIMMER SWITCH.
AS ILLUSTRATED BELOW, THE NET SUM OF ALL THESE FACTORS DETERMINES THE STP, SHOWN ON THE SEXUAL BALANCE SCALE AT ANY MOMENT IN TIME.
Inhibition
Excitation
EACH DIMMER IS LIKE A MICRO VARIABLE SWITCH THAT SYMBOLIZES A FACTOR’S VARYING POLARITY (+,-,=) & MAGNITUDE
Perelman MA. The Sexual Tipping Point is a Variable Switch Model. Curr Sex HealthRpts 2018;10:1.
© 2018 MAP Education & Research Foundation
Perelman MA. The Sexual Tipping Point is a Variable Switch Model. Curr Sex HealthRpts 2018;10:1.
THE STP ALSO ILLUSTRATES HOW EACH INDIVIDUAL FACTOR (DIMMER) CAN DEVIATE FROM A “NORMAL” RANGE, AND THUS, HELP TO IDENTIFY WHETHER THAT FACTOR IS PREDISPOSING, PRECIPITAITING AND/OR CURRENTLY MAINTAINING A SEXUAL DISORDER.
THE SEXUAL TIPPING POINT MODEL
Inhibition
Excitation
THE STP ILLUSTRATES HOW MANY OF THESE FACTORS
CAN BE BI-DIRECTIONAL & EVEN SIMULTANEOUS IN THEIR IMPACT
© 2023 MAP Education & Research Foundation
Numerous Physical Factors In the Brain Can Excite Or Inhibit
Complements of Jim Pfaus
Neuronal inhibition can be the complement to neuronal excitement (Komisaruk et al, 2023).
The proposed mechanism of action for Flibanserin (Addyi) is attributed to displaying agonist activity on 5-HTA1 and antagonist on 5-HTA2, resulting in lowering of serotonin in the brain as well as an effect on increasing norepinephrine and dopamine neurotransmitters.
MENTAL: Thoughts Or Fantasy Can Also Be Bidirectional
1. I feel attracted to the person.
2. I want to experience physical pleasure.
3. It feels good.
4. I want to show my affection for my partner.
5. I want to express my love
6. I feel sexually aroused and want the release.
7. I feel horny.
8. It’s fun.
9. I am in love.
10. I love being swept up by the moment.
11. I wanted to please my partner.
12. I want the closeness/intimacy.
13. I want the pure pleasure.
14. I want an orgasm/orgasm
15. This is exciting,
16. I wanted to feel connected to the person.
17. The person's physical appearance turns me on.
18. Love this setting.
19. This person really desires me.
20. This person makes me feel sexy.
Turn On Thoughts
Turn Off:
Negative Thoughts
Meston, CM and DM Buss. "Why Humans Have Sex,”
Archives of Sexual Behavior (2007) 36:477.
Complements of Eli Lilly
© 2018 MAP Education & Research Foundation
MENTAL: Relationship Factors Are Also Bidirectional
© 2022 MAP Education & Research Foundation
MENTAL: RELATIONSHIP TENSIONS
CAN DEFINITELY RESULT IN SD
© 2022 MAP Education & Research Foundation
We Used To Teach That The 5 Most Common Issues Couples Argued About Were:
Domestic chores and Religion
It is not just marital tension, as divorce itself
can of course do the same!
An Ever More Common Chief Complaint:
“I found my husband watching porn and now I feel betrayed.”
Here An STP Cartoon Depicts the Etiology of A Man Who Suffers �From ED, Secondary to Being Humiliated by his Ex-wife!
© 2018 MAP Education & Research Foundation
Mental Factors = Psychosocial & Cultural
Accessed: 2022.01.31
www.psychologytoday.com/us/blog/sexual-tipping-point/201906/call-it-what-it-is-biomedical-psychosocial-and-cultural
MEDICAL VS PSYCHOSOCIAL BIOPSYCHOSOCIAL
VS BIOMEDICAL PSYCHOSOCIAL & CULTURAL MODEL
Eventually These Factors Will Be Shown As Vectors When This STP Cartoon
Can Be Illustrated In Three Dimensions.
© 2023 MAP Education & Research Foundation
What’s The Take-Away From This Talk’s First Section?
Second:
An individual’s sexual function at any given moment in time, is determined by the net sum of those factors.
Third:
Identify the key interfering
factors as initial treatment targets.***
© 2018 MAP Education & Research Foundation
Fourth:
Inspire hope by explaining
the STP formulation and
the initial treatment targets
to the patient.
First:
Recognize that SD is always determined by Biomedical Psychosocial & Cultural Factors
INHIBITION
A
M
P
P
M
EXCITATION
A
a questionnaire or a test.
history taking method
to uncover the key psychosexual- behavioral & cultural factors.
Kaplan HS, The Sexual Desire Disorders 1995;
Perelman MA. Int J Impot 2003; Res (15 Suppl 5):S67-74;
Perelman MA, FSD. In: Goldstein et al, 2005.
© 2018 MAP Education & Research Foundation
THE ANSWER IS A SEX STATUS.
PART TWO: SOME KEY TREATMENT CONCEPTS & TIPS: IDENTIFY KEY STP FACTORS AS THE PATH TO SUCCESS
A good Sexual Status creates a“video picture”in your mind about the friction, frequency, fantasy and feelings the patient is experiencing, by identifying the factors that precipitate and maintain the distressing sexual disorder.
Althof, Rosen, Perelman, Rubio. SOP for Sex History, JSM, 2013
Perelman MA. Int J Impot Res. 2005;15(suppl 50:S67-S74.
Perelman, In Balon & Segraves, 2005
Perelman, In Goldstein, FSD, 2005
© 2018 MAP Education & Research Foundation
Key Concepts & Questions To Optimize
Diagnosis & Treatment Of Sexual Dysfunction
HOW DO YOU DO THAT?
How do we do that?��Ask focused questions; step back and then probe again, depending on the patient’s comfort with the inquiry.
© 2018 MAP Education & Research Foundation
STP & Sex Status: Key Concepts to Optimize
Diagnosis & Treatment Of Sexual Dysfunction
Perelman M. Int J Impot 2003; Res (15 Suppl 5):S67-74;
Perelman MA. J Sex Med. 2006; 3:1004-1012.
Perelman MA. Int J Impot Res. 2005;15(suppl 50:S67-S74.
Perelman, In Balon & Segraves, 2005; Perelman, In Goldstein, FSD, 2005
© 2014 Michael A Perelman, PhD
and sexual experiences that illuminate the key factors.
who have been in your practice for years.
SEX STATUS: Taking a focused sex history is critical!
Perelman MA. Int J Impot Res. 2005;15(suppl 50:S67-S74.
Perelman, In Balon & Segraves, 2005
Perelman, In Goldstein, FSD, 2005
Sexual Status Exam
© 2018 MAP Education & Research Foundation
“ Tell me about your last sexual experience”
that helps me identify immediate and remote causes.
Sex Status Exam
You want to answer these questions:
(current cognitions, emotions, behaviors, organic, medical, etc)?
b. Any potential “deeper” mental and/or physical causes emerging?
(predisposing, precipitating)?
3. Do any underlying factors require pre-treatment, or can they be
bypassed, modified, or treated concurrently?
(eg. depression, marital conflict, drugs, ETOH, etc.
What Are The Critical Evaluation Issues?
© 2018 MAP Education & Research Foundation
Kaplan, 1983; Perelman, 2000, 2005
STP Approach To Treating SD
Althof et al, JSM, 2005; Althof et al, JSM, 2009;
Basson R. JSMT. 2000;
Hawton K. Br J Hosp Med 1985
© 2018 MAP Education & Research Foundation
EXPLAINING THE STP AND TREATMENT TARGETS,
NOT ONLY PROVIDES HOPE,
BUT BEGINS THE RECOVERY PROCESS
BY REFRAMING PATIENT COGNITIONS!
Question…where do you begin?
© 2022 MAP Education & Research Foundation
One of my easiest cases took place 35 years ago. He was a 60 y.o. man who suffered from ED and was referred by his urologist for a presurgical consultation for psych clearance prior to an intended penile prosthesis surgery. John was in excellent health and had maintained a rigorous exercise schedule as a marathon runner most of his adult life. Because of an achilles injury he no longer ran marathons, but still woke up early every morning to run 5 miles.
In our first session after complementing him on his regimen and good health, I asked what he thought the impact on his sex life might be if he cut the running back to 2 miles, three times a week and slept in later on the other 4 days. He laughed and said he would give it some thought. We scheduled a follow-up session to complete the evaluation .
Sometimes Brief Education
Is All That Is Needed To Assist The Patient/Partner
Accessed 2022.01.30: https://www.psychologytoday.com/us/blog/sexual-tipping-point/201808/the-link-between-lack-sleep-and-sex-problems
He cancelled 6 days later leaving me a message that he was running less frequently and for shorter distances. But he had already had two successful intercourse experiences with his wife, and they were both thrilled. Fortunately, the surgeon who himself became increasingly more sophisticated about sexual response continued referring to me.
© 2022 MAP Education & Research Foundation
Perelman MA. Int J Impot Res. 2005;15(suppl 50:S67-S74.
Perelman, In Balon & Segraves, 2005
Perelman, In Goldstein, FSD, 2005
Therapeutic Probe & The Sexual Status Exam
© 2018 MAP Education & Research Foundation
such as: , SF, self exploration, S/S, etc.
Importance of Follow-Up
Barada, 2001 Hatzichristou, 2001 Perelman 2000,2002
© 2018 MAP Education & Research Foundation
Weaning & Relapse Prevention�
Perelman, IJIR,2004;
Perelman M. Handbook of Sexual Dysfunction 2005
Perelman, In Goldstein, FSD, 2005
© 2018 MAP Education & Research Foundation
WHEN TO REFER
Medication & Education Alone Will Succeed
Perelman, IJIR, 2004
Perelman M. Handbook of Sexual Dysfunction 2005
Perelman M. Urol Clin North Am. 2005;32:431-445.
© 2015 Michael A Perelman, PhD
Future SD Treatments
© 2018 MAP Education & Research Foundation
Sexual Balance: STP Illustrating an Integrated Treatment
of HSDD Secondary to VVS & ED
There Will Be New Drugs
PART TWO: SOME KEY TREATMENT �CONCEPTS, TIPS & EXAMPLES
© 2022 MAP Education & Research Foundation
With The Introduction Of Sexual Pharmaceuticals My Interest Shifted To Combination Treatments
© 2006 Michael A. Perelman, PhD.
GOAL: Identify key non-medical treatment variables that could improve safety and efficacy, knowing that guaranteed “a place at the table” given Pharma’s medical hegemony at that time.
Most Important Diagnostic Issue To Clarify, Is Whether
He Can Differentiate PS From Emission (EI) & Ejection
Men with PE typically lack skill in identifying PS and/or adequately managing their body’s response to PS (progressively escalating sensations of sexual arousal during coitus), regardless of other predisposing etiological factors; whether genetic serotonin thresholds, nerve transmission rates, or psychosocial- cultural variables.
Perelman M. J Sex Med 2006;3:1004-1012
PE FINAL PATHWAY:
© 2018 MAP Education & Research Foundation
THE MOST IMPORTANT KEY TO PE CASES
Treating PE Is More Than Just Improving IELT.
ISSM Definitions Also Emphasize Control & Distress!
AUA PE Guidelines, 2004;
Perelman, M. Handbook of Sexual Dysfunction, 2005
Perelman MA. J Sex Med. 2006;3:1004-1012.
© 2018 MAP Education & Research Foundation
Medical Tx. of PE is limited, by PE’s multi-dimensional etiology.
Is Assessing His Capacity To Discern The Difference Between PS & Emission Necessary ?
Yes! And especially for physicians who treat with meds!
“Uh -oh; I’m going to come now!”
MOST OF THESE MEN DO NOT HAVE A CHOICE!
HE SUFFERS FROM AN INABILTY TO DELAY
AND HAS NO CHOICE!
An orgasm is like a sneeze, he needs to get a clue before it happens!
https://www.psychologytoday.com/us/blog/sexual-tipping-point/201810/what-does-sneeze-and-premature-ejaculation-have-in-common
“Shoot I’m coming.” He’s confusing strong PS, with the emission stage of his ejaculation.
Three Common Errors Made By Men With PE
Perelman, 2005 SMSNA PE Debate
© 2018 MAP Education & Research Foundation
Can He Identify His �Premonitory Sensations (PS)?
In that case a medication is needed to reset this threshold, or “ejaculatory tipping point” so that he has the time to more easily recognize, and respond to PS ?
Perelman M. J Sex Med 2006;3:1004-1012
PE’S FINAL PATHWAY:
© 2006 Michael A. Perelman,
WHAT TO DO: AN ELEGANT SOLUTION: �AN INTEGRATED TREATMENT FOR THE METABOLIC SYNDROME PATIENT.
INTEGRATED TREATMENT: THE IDEAL SOLUTION TO BALANCE RISK/BENEFIT
Counseling
?
PDE-5
NEW DRUG
?
© 2018 MAP Education & Research Foundation
WHY DE Is A Disorder Which You Can Treat With Greater Facility Than Most Urologists
© 2022 MAP Education & Research Foundation
DE IS AN EJACULATORY DISORDER WHICH SHOULD CAPTURE YOUR INTEREST!
Simons J, Carey MP (2001) Prevalence of sexual dysfunctions: results from a decade of research. Arch Sex Res 30(2):177–219 , Masters WH, Johnson VE (1970) Human sexual inadequacy. Little, Brown & Co: Boston., Apfelbaum B (2000) Retarded ejaculation; a much-misunderstood syndrome. In: Lieblum SR, Rosen RC, eds, Principles and practice of sex therapy, 2nd ed, Guilford Press: New York, pp 205-241. Kaplan H (1995) The evaluation of sexual disorders: psychologic and medical aspects. Brunner/Mazel: New York. Perelman M, McMahon C, Barada J (2004) Evaluation and Treatment of Ejaculatory Disorders. Atlas of Male Sexual Dysfunction, Current Medicine LLC, Philadelphia, pp 127–157. Perelman MA (2003). Regarding ejaculation: delayed and otherwise. J Androl 24:496. Perelman MA, Rowland DL. “Retarded Ejaculation.” World Journal of Urology, 2006 Dec;24(6):645-52.
© 2022 MAP Education & Research Foundation
TREATING DE IS A BIG OPPORTUNITY
FOR SEX THERAPISTS!
DE: TREATMENT
WHY?
(there is some Level 3 evidence for PDE-5s.) (Nurenberg, Segraves, Clayton, Ashton)
Perelman & Rowland, WJU, 2006; Perelman, WAS, 2007
© 2022 MAP Education & Research Foundation
Psychosexual Therapy Should be Considered First Line Therapy for the Management of Delayed Ejaculation
“And thanks, to the AUA, for their summer program’s emphasis on:
“Clinicians should consider referring men diagnosed with lifelong or acquired delayed orgasm to a mental health professional with expertise in sexual health.”
Recognizing the role of mental health professionals
in managing disorders of ejaculation.”
“And most important to this debate:
Thanks to Dr. Shindel, for Chairing the AUA Committee,
“Guidelines On Ejaculation Disorders,” which recommended:
© 2022 MAP Education & Research Foundation
DEBATE
DEBATE
Psychosexual Therapy Should be Considered First Line Therapy for the Management of Delayed Ejaculation
“And thanks, to the AUA, for their summer program’s emphasis on:
“Clinicians should consider referring men diagnosed with lifelong or acquired delayed orgasm to a mental health professional with expertise in sexual health.”
Recognizing the role of mental health professionals
in managing disorders of ejaculation.”
“And most important to this debate:
Thanks to Dr. Shindel, for Chairing the AUA Committee,
“Guidelines On Ejaculation Disorders,” which recommended:
© 2022 MAP Education & Research Foundation
DEBATE
DEBATE
Psychosexual Therapy Should be Considered First Line Therapy for the Management of Delayed Ejaculation
“You only need to ask key questions and provide crucial suggestions to make a difference in their lives!”
© 2022 MAP Education & Research Foundation
Perelman, M, “What a Sex Therapist Wants You To Know About Treating Men With Sexual Disorders,”
In Essentials of Mens’ Health, Ed. O’ Leary, M and Bhasin, S. McGraw-Hill Global, 2020.
Perelman, M, Invited Commentary: Sex Coaching for Non-Sexologist Physicians: How to Use
the Sexual Tipping Point Model. The Journal of Sexual Medicine, Vol.15, Issue 12. Dec. 2018.
But the title of this debate should have been:
Why Is That?
ejaculate with self-stimulation.
© 2022 MAP Education & Research Foundation
The.embedded poster is from this AUA presentation
WHAT TO DO FIRST?
© 2022 MAP Education & Research Foundation
Ask specific questions like:
Perelman, M, Invited Commentary: Sex Coaching for Non-Sexologist Physicians: How to Use the Sexual Tipping Point Model. The Journal of Sexual Medicine, Vol.15, Issue 12. Dec. 2018.
High Frequency & Idiosyncratic Masturbation
Now in the AUA Guidelines chaired by Dr. Shindel:
for those seeking greater understanding.
© 2021 Michael A Perelman, PhD
https://www.auanet.org/guidelines/guidelines/disorders-of-ejaculation, accessed 2021.10.15
http://www.mapedfund.org, accessed 2021.10.15
My 2005 AUA poster first documented “Idiosyncratic Masturbation” and high frequency masturbation as hidden causes of DE.
DEBATE
���
If You Or Your Patient Are Uncomfortable With This Strategy
Recognize The Following Yourself And Tell Him:
© 2021 Michael A Perelman, PhD
The Psychology Today Blog called:
“Why Delayed Ejaculation Is More Common Than Folks Realize.” summarizes masturbation’s putative role in the etiology of DE.
https://www.psychologytoday.com/us/blog/sexual-tipping-point/201812/why-delayed-ejaculation-is-more-common-folks-realize
DE Will Often Require Alteration of Masturbatory Habits: Whether Type of Friction, Frequency and/or Fantasy
finding ways to increase the quality of friction and erotic thought per the Sexual Tipping Point Model.
limit ejaculatory release to his/their desired goal activity:
-- Usually penetrative sex.
the desire for a “release” to increase, and the stimulation needed to ejaculate during partnered sex to more easily occur.
success during partnered sex, has increased probability.
© 2021 Michael A Perelman, PhD
Perelman, M. “Understanding, Diagnosing and Treating Delayed Ejaculation Using the Sexual Tipping Point Model,” In P. Nobre et al (eds), Encyclopedia of Sexuality and Gender, Springer International Publishing AG, 2021.
���
If You Or Your Patient Are Uncomfortable With This Strategy
Recognize The Following Yourself And Tell Him:
© 2021 Michael A Perelman, PhD
The Psychology Today Blog called:
“Why Delayed Ejaculation Is More Common Than Folks Realize.” summarizes masturbation’s putative role in the etiology of DE.
https://www.psychologytoday.com/us/blog/sexual-tipping-point/201812/why-delayed-ejaculation-is-more-common-folks-realize
Thank You �For Listening!
© 2018 MAP Education & Research Foundation
The STP Model Helps Optimize The
Diagnosis & Treatment Of SD
Other STP videos and related publications and presentations
are available free at: mapedfund.org
For questions contact michael@mapedfund.org