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9 of 72

Which two people were initially given the most credit for discovering the structure of DNA?

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1-100A

1 - 100

$100

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Who was never given the full credit they deserved for their part in helping discover the structure of DNA?

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1-300A

1 - 100

$200

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In which decade did Watson and Crick make their famous discovery?

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1-400A

1 - 100

1950s

(1953)

$300

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Whose work helped others figure out base pairing rules?

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1-500A

1 - 100

Erwin Chargaff

$400

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2-100

1 - 100

Explain the process of Xray diffraction. What role did this process play in helping illucidate the structure of DNA?

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2-100A

1 - 100

X ray diffraction.

X rays are aimed at an object X rays are aimed at an object and when they hit the object they scatter creating a pattern that is like a shadow of the original object that they hit. Rosalind Franklin used X ray diffraction to look at DNA patterns. One of Rosalind Franklin’s X ray diffraction prints helped confirm Watson and Crick’s hypothesis about the structure of DNA.

$500

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What is the building block of a nucleic acid?

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2-200A

1 - 100

a nucleotide

$100

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2-300

What two types of nucleic acids have you learned about in class?

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2-300A

1 - 100

DNA and RNA

$200

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2-400

In RNA what base will attach to and adenine?

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2-400A

1 - 100

Uracil

$300

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2-500

Explain how the sugars in DNA and RNA are different.

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2-500A

1 - 100

The sugar in RNA is ribose. It has one more oxygen (at the second carbon) than the sugar in DNA, deoxyribose.

$400

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3-100

1 - 100

List and explain 4 important differences between DNA and RNA.

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3-100A

1 - 100

$500

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3-200

Where does transcription take place?

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3-200A

1 - 100

$100

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3-300

What is the product of transcription?

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3-300A

1 - 100

$200

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What enzyme adds RNA nucleotides to create the messenger RNA?

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3-400A

1 - 100

$300

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4-100

1 - 100

What is the section of DNA that gets transcribed called?

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3-500A

1 - 100

$400

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4-200

What is the start codon found on mRNA for all proteins?

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4-100A

1 - 100

$500

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4-300

Where does translation occur?

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4-200A

1 - 100

Ribosome

$100

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4-400

What is the product of translation?

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4-300A

1 - 100

an amino acid chain that folds to become a protein

$200

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4-500

Where is the codon located?

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4-400A

1 - 100

mRNA

$300

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5-200

What is the role of the tRNA?

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5-100A

1 - 100

to bring amino acids to the ribosome so they can bond together (peptide bond) and form a polypeptide chain

$400

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5-200

Translation takes place in the free floating ribosomes of the cell. Where is another place in the cell that translation occurs?

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5-200A

1 - 100

Rough endoplasmic reticulum…it is ribosomes that make it rough

$500

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5-300

When does DNA replication occur?

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5-300A

1 - 100

Before the cell divides.

$100

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5-400

What enzyme unzips the DNA?

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5-400A

1 - 100

helicase

$200

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Which enzyme helps seal up the Okazaki fragments?

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5-500A

1 - 100

ligase

$300

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6-100

1 - 100

During DNA replication, why is there a leading strand with continuous new DNA, and a lagging strand with discontinuous segments of newDNA?

Be specific.

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6-100A

1 - 100

DNA is read in the 3 prime to 5 prime direction (created 5 to 3 prime). Since the new DNA is created before the whole DNA strand unzips, and 3 prime end is on opposite sides of the ladder, one side can only be created in segments.

$400

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6-200

Explain DNA replication in detail. Include all steps.

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6-200A

1 - 100

  1. Helicase unzips the DNA

  • DNA polymerase adds DNA nucleotides in the 3 to 5 prime direction of old DNA.

  • One side is continuous and one is discontinuous.

  • Discontinuous Okazaki fragments are bonded together by ligase.

$500

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6-300

Which famous man was in the race to discover the structure of DNA, but did not have the structure correct?

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6-300A

1 - 100

Linus Pauling

He was favored by many to be the person who would discover that DNA structure since he had discovered the structures of many other molecules. His model incorrectly had the bases on the outside of the DNA molecule.

$100

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6-400

What enzyme helps open the DNA molecule before more DNA can be made?

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6-400A

1 - 100

helicase.

$200

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6-500

What molecule is responsible for putting attaching new DNA nucleotides during replication?

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6-500A

1 - 100

$300

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6-500

What is DNA fingerprinting (RFLP) and how is it used?

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6-500A

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Restriction Fragment Lenth Polymorphisms

DNA fingerprinting is a process by which DNA is cut up into small pieces by restriction enzymes and run out onto a gel. The gel pattern is then read.

Uses: identification of suspects in a crime

paternity suits

identification of markers for genetic disorders

$400

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6-500

Explain what happens to get the information from a gene to a protein. Explain as many steps as possible.

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6-500A

1 - 100

Step 1 = Transcription:

-DNA opens at the gene

-RNA polymerase adds RNA nucleotides.

-mRNA breaks away from the DNA

Step 2 = mRNA processing or splicing.

-Introns are spliced out of the mRNA and exons are sometimes rearranged.

�Step 3 = Translation.

-In the ribosome, mRNA codons pair with tRNA anticodons.

-amino acids at the top of the tRNA bond together.

-A long chain of aminoacids is created.

-It breaks away, folds up, and bonds with other chains to become a functional protein.

$500

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In which part of the cell cycle is the cell growing and doing its main functions?

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During what part of the cell cycle

does the nucleus divide?

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Mitosis

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