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Cell Communication

Signal Transduction

Cell Cycle

BIOGO

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Randomly fill in your BIOGO sheet with the terms:

Autocrine Secondary Messenger Phosphatases

Juxtacrine Amplification G-Protein Cyclins Stimulating Proteins

Endocrine Response Positive Feedback Cyclin Dependent Kinases

Paracrine Steroid Negative Feedback G1 G0 S

Ligand Protein Receptor Mutations G2 Mitosis

Receptor Phosphorylation Prophase Metaphase

Active Relay Protein Kinases Inhibitors Anaphase Telophase

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What bonds to a cell receptor to initiate a cell response?

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What bonds to a cell receptor to initiate a cell response?

Ligand

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What happens during signal transduction to increase the number of molecules used to initial a response?

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What happens during signal transduction to increase the number of molecules used to initial a response?

Amplification

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Helper T and B cells must contact each other in order to illicit the production of antibodies. What type of cell communication does this illustrate?

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Helper T and B cells must contact each other in order to illicit the production of antibodies. What type of cell communication does this illustrate?

Juxtacrine

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Underlying disease can cause cardiac cells to secrete growth factors that causes the same cells to grow. This is an example of which type of cell communication?

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Underlying disease can cause cardiac cells to secrete growth factors that causes the same cells to grow. This is an example of which type of cell communication?

Autocrine

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The cells in the thyroid gland produce T-3 and T-4 which circulate throughout the body via the bloodstream and regulate the metabolic activity of all cells. This is an example of which type of cell communication?

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The cells in the thyroid gland produce T-3 and T-4 which circulate throughout the body via the bloodstream and regulate the metabolic activity of all cells. This is an example of which type of cell communication?

Endocrine

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What type of molecule is lipid based and can move through a cell membrane to illicit a cell response?

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What type of molecule is lipid based and can move through a cell membrane to illicit a cell response?

Steroid

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When the stomach is empty, cells in the stomach secrete a hormone called ghrelin which travels via the bloodstream to the brain and stimulates appetite. The person eats which causes the stomach to stretch and ghrelin production is inhibited. This is an example of….

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When the stomach is empty, cells in the stomach secrete a hormone called ghrelin which travels via the bloodstream to the brain and stimulates appetite. The person eats which causes the stomach to stretch and ghrelin production is inhibited. This is an example of….

Negative Feedback

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G Protein is an example of a(n)....

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G Protein is an example of a(n)....

Active Relay Protein

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What enzymes help amplify signals by transferring phosphate groups from ATP to proteins.

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What enzymes help amplify signals by transferring phosphate groups from ATP to proteins.

Kinases

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What molecules rise and fall throughout the cell cycle?

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What molecules rise and fall throughout the cell cycle?

Cyclins

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What molecules bond to cyclins as their concentrations increase to initiate acceleration or inhibition of the cell cycle?

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What molecules bond to cyclins as their concentrations increase to initiate acceleration or inhibition of the cell cycle?

Cyclin Dependent Kinases

CDKs

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What can inhibit the effectiveness of proteins used in signal transduction?

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What can inhibit the effectiveness of proteins used in signal transduction?

Mutations

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During cell cycle checkpoints molecules can accelerate progression to the next cycle. What are these molecules called?

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During cell cycle checkpoints molecules can accelerate progression to the next cycle. What are these molecules called?

Stimulating Proteins

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During cell cycle checkpoints molecules can halt progression to the next cycle. What are these molecules called?

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During cell cycle checkpoints molecules can halt progression to the next cycle. What are these molecules called?

Inhibitors

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MAD (mitotic arrest deficient) proteins inhibit APC/C (anaphase promoting complex) from destroying proteins that hold sister chromatids together if the spindle fibers are not properly connected during which phase of mitosis?

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MAD Proteins inhibit APC/C from destroying proteins that hold sister chromatids together if the spindle fibers are not properly connected during which phase of mitosis?

Metaphase

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What phase is initiated if the cell does not have enough resources during G1?

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What phase is initiated if the cell does not have enough resources during G1?

G0

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What phase of the cell cycle is shown below?

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What phase of the cell cycle is shown below?

Anaphase