Cell Division

Interphase

Prophase

“first”

• Chromatin coils to form chromosomes
• Nucleolus & nuclear envelope disappear
• Centrioles appear (animal) & begin to produce the spindle fibers – microtubules that function to move chromosomes & separate sister chromatids.

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Centrioles

Metaphase

“middle”

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• Kinetichore fibers push & pull chromosomes to the middle of the cell.

Anaphase

“Apart” “Away”

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• Centromeres break in half
• Sister chromatids separate and move towards opposite poles of the cell.

Telophase

“Far” “End”

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• Chromosomes are clustered at the poles
• Centrioles and spindle fibers disappear
• Chromsomes uncoil into chromatin
• Nuclear envelope reforms around each mass of chromatin
• Nucleolus reappears

Cytokinesis

Animal cell: Flexible cell membrane pinches inward forming an indentation called a cleavage furrow.

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Plant cell: Golgi bodies produce vesicles which line up at the equator & fuse to form a cell plate. Cell walls are then constructed.

Animal Cell

Plant Cell

Cleavage Furrow

Can You name That Phase??

Interphase

Metaphase

Prophase

Telophase & Cytokinesis

Anaphase

Contact Inhibition

Normal cells will

stop dividing when

they come in contact

with neighboring cells.

Contact Inhibition

Abnormal cells

will not stop

dividing, but will

pile up on top of

one another.

Cancer�The uncontrolled division of cells

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• Will result in the formation of a tumor – a mass of cancer cells.

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• Believed to be caused by mutations in the genes that code for the enzymes that regulate the cell cycle.

Animations

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Cell Cycle (Mitosis)

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Cancer Animation

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