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Setting Evidence Based Medicine on FHIR ��Interoperability for External Evidence: Make Evidence Computable

AMDIS Ted Talk, October 1, 2020

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Disclosures and Contact Info

Brian S. Alper, MD, MSPH, FAAFP, FAMIA

Chief Executive Officer, Computable Publishing LLC

www.ComputablePublishing.com

balper@computablepublishing.com

Founder of DynaMed, www.dynamed.com

Project Lead, EBMonFHIR www.tinyurl.com/EBMonFHIR

Project Lead, COVID-19 Knowledge Accelerator www.tinyurl.com/coka2020

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LOCATION KNOWLEDGE – SOCIETAL EVOLUTION

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LOCATION KNOWLEDGE – SOCIETAL EVOLUTION

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LOCATION KNOWLEDGE – SOCIETAL EVOLUTION

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Executable

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LOCATION KNOWLEDGE – SOCIETAL EVOLUTION

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Computable

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DIGITAL EVIDENCE

Published July 17, 2020

https://www.nejm.org/doi/pdf/10.1056/NEJMoa2021436

CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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DIGITAL EVIDENCE

Published June 16, 2020 https://gps.health/coka/resources/Citation/36404

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CLINICAL �EVIDENCE

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What I about to show you was first available June 22, 2020:

Alper BS, Mayer M, Shahin K. Dexamethasone Treatment for COVID-19: Clinical Outcomes Results Extracted from Randomized Controlled Trials. COVID-19 Knowledge Accelerator Evidence Reports, entry 28, version 2020-07-20. Created 2020 Jun 22. Revised 2020 Jul 20. Available at: https://gps.health/coka/reports/EvidenceReport/28. Computable resource at: https://gps.health/coka/resources/EvidenceReport/28?version=8

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CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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CLINICAL �EVIDENCE

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Current COKA Efforts

  • Maintaining FHIR Resources: Citation, Evidence, EvidenceReport, EvidenceVariable, OrderedDistribution, Statistic
  • Creation of Code Systems (universal terminologies):
    • Study Design Code System
    • Statistic Type Code System
    • Statistic Model Code System
    • Risk of Bias Code System
  • Facilitation of tools development
  • Systematic meta-review (systematic review of systematic reviews of steroids for COVID-19)

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COKA Weekly Meeting Schedule

Day

Time (Eastern)

Team

Monday 

7-8 am 

Project Management

Monday 

9-10 am

Systematic Meta-Review

Monday

4-5 pm

Statistic Model Code System Development

Tuesday 

10-11 am 

Evidence Evaluation and Reporting Tools Development

Tuesday 

2-3 pm 

Study Design Code System Development

Wednesday

8-9 am 

Knowledge Ecosystem Liaison

Wednesday

9-10 am

Statistic Type Code System Development

Thursday 

7-8 am 

Project Management

Thursday

9-10 am

Content Citation and Classification Tools Development

Thursday 

4-5 pm 

Project Management

Friday

9-10 am 

Risk of Bias Code System Development

Friday

10-11 am 

Communications (Awareness, Scholarly Publications)

For all of these meetings: Join Microsoft Teams Meeting

If you wish to sign up or learn more about COKA please go to

Tinyurl.com/coka2020

Questions: balper@computablepublishing.com