MAGIC

Final Presentation

Stella K. Abraham High School, NY

May 29, 2019

  • Chani Rabinow, 9th Grade
    • TechKNOWLEDGEy
  • Anna Laufer, 10th Grade
    • Understanding Vaping
  • Ariella Borah, 10th Grade
    • Antibiotic Resistance
  • Ayelet Teitelbaum, 10th Grade
    • Name Hands-On

  • Riki Posner, 10th Grade
    • Endocrine System Quiz App
  • Priva Halpert, 10th Grade
    • Alcohol Detection Using Image Analysis and Color Changing Methods
  • Eliana Millstone, 12th Grade
    • Hydro Car

Agenda

Chani Rabinow

9th Grade

  • A few bullet points about your mentor
    • Dr. Hindi Lunzer
    • Works at NYU school of medicine and north well
    • Has a practice in Great Neck
    • My mentor is a physician.
    • She is from New York
    • Enjoys gardening and reading.

My Mentor

  • Project:
    • TechKNOWLEDGEy
    • What it is: Clinical Research Project
    • Why I chose this project: I am interested in studying the impact of smartphones tablets and television on the development of children
    • What I tested for: how smartphones and watching tv may slow down the development of children
    • Hypothesis: if children are exposed to electronic devices often then they will have a shorter attention span than children that are rarely exposed smartphones, tablets or televisions.
    • Foundation of experiment: a 2x2 research design and survey,(the first variable is what they are watching,(a device) and the other is how long they are watching)
    • Go on to explain why specifically this project

My Project

    • Step one: Read a book to small group of children who are around five years old, and are constantly exposed to electronic devices( between three and five hours ) This include smartphones tablets and tvs
    • Step two: Ask the children three questions on the book that they just heard and saw picture from
    • Step three: Record results.
    • Step four: Tell the children a story but don‘t show them any picture from the book.
    • Step five: Ask the children three questions on the book that they just heard.
    • Step Six: Results results
    • Step seven-step twelve: repeat experiment with children who are not exposed to technology as often (less than one hour a day)

Experiment

t

These are the books that I will be using.

Process

In order to perform the testing necessary on human subjects, the experiment had to be approved

by the Institutional review board (IRB)committee.

  • This is a committee that reviewed the ethics of the proposed experiment to ensure that the rights and welfare of the children were protected.
  • In addition, because the subjects were young children, I needed parental permission
  • This added to the delay in conducting the experiment so that only a demonstration was possible.

  • Results
  • When I tested the children that were shielded from screen time, they got on average six questions correct out of the six that I asked
  • The children that were exposed to screen time got on average about four and a half questions correct out of the six that I asked with only a 75% accuracy rate versus the leading 100%
  • When the children who were exposed to technology got asked to perform the second part of the test, they failed to pay as well attention.
  • These results confirmed my hypothesis of the project

Results

  • If I were to repeat this project in the future I would change multiple things
  • begin the the process to obtain an IRB and subjects earlier
  • conduct the experiment with a larger group of people
  • test different age groups
  • test groups where the difference in screen time exposure could be measured for example finding a group of people that have absolutely no access to technology such as amish.
  • use a more complicated set of questions

The Future

  • A few bullet points about your experience
    • My favorite part of magic, is where you get involved in different topics that you are interested in. For example, I would like to become a Pediatrician and in my experiment I will be able to interact directly with children.
    • In addition, it allows me to have a mentor who guides me, and gives me new perspectives on science and technology.

My MAGICal Experience

  • Lessons that I have learned:
    • One lesson that I learned is that in a research experiment there are a lot of different factors that all have to work together to form one cohesive project
    • Another lesson that I learned is the impact of Nature vs. Nurture. There are so many things that go into child development. It is not only what they are gifted with, but also what you expose them to, has a direct influence on how children turn out.
  • Challenges:
    • One challenge that I am having with my experiment, is finding a control group. This task is very hard because there are very few children in the world that have limited exposure to any technology.

My MAGICal Experience.

Thank You!

Anna Laufer

<Grade 10>

My Mentor

    • Leah Einhorn
    • Works at Kepler Group, New York City
    • She builds web apps and databases, and uses machine learning to analyze data
    • She lives in Monsey, New York
    • She enjoys playing board games, reading, and dancing

Understanding Vaping

    • Expose the public to the dangers of vaping
    • Learn web development and machine learning

Understanding Vaping

    • Create a website to inform adults and children
    • Target this website to those susceptible to vaping

Things I Learned

        • Build a website and make it live
          • Html
          • Css
            • Bootstrap library
          • Github

Things I Learned

        • Solving logical programming problems such as Project Euler
        • Navigating datasets finding specific data relevant to my work
        • Machine learning and the different algorithms that can be used
          • Python
            • Pandas

Past and Future Work

    • Finished the website and it is live
    • Chose a dataset and chose relevant pieces to my project
    • Loaded and cleaned data into a format that will allow it to be analyzed
    • Narrowed down algorithm to build my model
    • Future Work:
      • Feed data to algorithm to produce a model that will predict those likely to vape

My MAGICal Experience

      • Learning how to code in order to create websites and use machine learning
      • Exploring a topic that I previously worked with in a new lens
      • Gaining the ability to work independently in completely new areas I never worked in in school
      • The ability to work with someone who specializes in feilds I am interested in

Highlights

      • Sometimes you run into errors that affect the whole project no matter how small
      • In order to accomplish what you’re working on you must put in large amounts of time
      • Asking for help allows you to be able to tackle tasks independently in the future

Lessons Learned

      • Learning how to approach problem solving with Python
        • Learning how to break down the problem helped overcome this obstacle
      • It was hard to find datasets in the topic of vaping as its a new field
      • Once we found a dataset, it did not easily open
        • The dataset was such a large size, that once we found it, we could not load the entire spreadsheet!
      • After going through the difficulties and the need for precise syntax, I learned how to find errors and keep working

Challenges

My Demo

Thank you!

Ariella Borah

<Grade 10>

My Mentor

  • Dr. Bishakha Mona, PhD neuroscience
    • Is currently doing research at UT Southwestern about how we feel pain and itch
    • Originally from India, came to the U.S. for research
    • Hobbies include dancing and reading, amongst others
  • My Experience

    • Highlights
      • Learning about a new aspect of science
      • Doing independent research
      • Being able to consult with a mentor, to help me better understand the material
    • Lessons Learnt
      • How to research a topic, in depth
      • How to design a proper, scientific, experiment

My MAGICal Experience

My Project

  • Antibiotic Resistance
    • Type of Project - Scientific research
    • Why I Chose This Project Antibiotic Resistance is an extremely important issue in today’s day and age. Seeing that antibiotics are such an essential component of modern medicine, it is imperative that antibiotic resistance is addressed before it claims any more lives. By researching resistance I am learning about a current issue that is of the utmost importance.

Resistance News

Resistance Worldwide:

EU-25,000 deaths per year;

INDIA-over 58,000 babies die per year

THAILAND-38,000+ deaths per year

UNITED STATES-23,000 deaths per year

This is a map representing...

Bacteria

Bacteria are all around us…

  • The bacteria in out bodies outnumber our own cells 10:1
  • There are approximately 5 million trillion trillion bacteria in the world
  • Though not all bacteria are harmful, before the discovery of antibiotics they accounted for millions of deaths (and still do today

Diseases caused by bacterial infections and to treat them antibiotics are given

Antibiotics fight these harmful bacteria, saving millions of lives in the process...

Antibiotics:

Bacteriostatic - bacteria can communicate with each other, so if one dies the other will try to evolve; if something is bacteriostatic there is no stress signal, so then the dosage becomes very important; then the body clears up the bacteria on its own; there are more known antibiotics that are bactericidal; the dosage can be much higher for bacteriostatic because you don’t want to shock your body too much and send off to much stress signals

Bactericidal - they destroy the cell wall, causing the cell to burst and die.

Broad Spectrum - kill more than one type of bacteria, not just a specific type

Targeted - only kill a specific type of bacteria

Penicillin

First Antibiotic

Bactericidal

Broad Spectrum

Bactericidal

Broad Spectrum

Most commonly prescribed

Ampicillin

Write bactericidal broad spectrum and bacteriostatic broad spectrum and say penicillin was first. And say ampicillin and amoxicillin are the most common antibiotics given. Get a list of common combination therapies

Bactericidal

Broad Spectrum

Most Commonly Prescribed

Amoxicillin

Broad Spectrum

Bacteriostatic

Azithromycin

  • 200 million lives have been saved by the discovery of penicillin
  • 269.4 million antibiotics were prescribed by healthcare providers in the past year In the US alone
    • That is 5 out of every 6 people

Antibiotics Worldwide:

Early Penicillin

Early Penicillin Uses

Bacterial Infections

Experimental Plan

Planned to Test: The effect of different concentrations of bacteriostatic and bactericidal antibiotics on bacterial growth of cultures taken from locations in the community.

What we wanted to test was… But we couldn't because of technical issues

Bacteria Resistance Study at Harvard

Start video at 55 seconds and say what's going on first

Growth rate was 5-6 days

Arctic circle because of dumping of human waste

Scientists are now trying to come up with therapies that target bacteria in a different ways (target the bacterial DNA - different than humans DNA)

This is a graph showing the effect of antibiotic concentration on the rate of evolution of bacteria. As you can see, it is in the stage of low antibiotic concentration where the rate of evolution is highest.

This is why it is so important to be extremely careful with antibiotics and to

  • Never take antibiotics unless they are truly necessary
  • Always finish the dosage prescribed, or else the bacteria will become resistant because you are providing them with the low-concentration environment that is key to stimulating their evolution

Add in 2B as resulting graph and talk about taking the right dosage of antibiotics and we want to kill the bacteria before they reach the stage of resistance. Can't evolve fast enough because they have no gradual stage

Thank you!

Ayelet Teitelbaum

10th Grade

My Mentor

  • A few bullet points about my mentor:
    • Gittie Atlas
    • My mentor works at Duvy’s Media
    • She works in web development there
    • Is from Lakewood, NJ
    • Her hobbies include playing drums and painting
    • Is an amazing mentor

My Project

  • Name: Hands-On
    • What it is: a website which can translate ASL into English
    • Why I chose this project: I knew I would learn a lot about coding and creating websites from it, and it could potentially help many deaf people
    • Topics and technologies learned: html, css, python, machine learning, using github, using the terminal on a computer, using a dataset, tensorflow, openCV

My Project

    • How far I got: so far I have created the informational homepage for the Hands-On website, and created a basic translator from ASL to English
    • Future works: future updates to improve my project would include linking my translator to the Hands-On website and improving the translator to make it more accurate
  • A few bullet points about my experience
    • Highlights
      • Learning to see how things on my computer really work, in terms of the coding behind them
      • Getting to use what I learned to create different parts of my project
    • Lessons I learned
      • You do not need to start completely from scratch when coding, but need to know how to change code to perform different functions
      • When debugging it is important to think outside the box because the problem could be something small and hard to notice

My MAGICal Experience

My Demo

  • My demo: I have used css and html to code the informational homepage for my website. This page includes information regarding the translator and how it works. I have also created the actual translator for ASL to English text. When using this translator, users speak sign language with their hand in a small rectangle on the screen. Using a dataset of images, algorithms, and python, the translator then translates ASL into English text on the screen. Through machine learning, the translator will become more accurate the more it is used.

Informational website home page

Thank you!

Riki Posner

10th Grade

My Mentor

  • Shami Ahuja
    • She did her masters in computer science from UTA and currently works in the Bay area
    • Manages technical projects
    • Mumbai, India
    • She likes to listen to music, cook and read

My Project

  • Quiz on the Endocrine system
    • This is an app to learn about the endocrine system while going through a quiz
    • Endocrine system was my favorite subject in bio
    • I wanted to learn how to code
    • Topics and technologies learned
      • Endocrine system
      • Scratch
      • ZOOM
    • Finished making the game
    • Show it to others

  • Highlights
      • This was my first time coding out of class
      • Learning how to use a new program
      • Making something that I care about and want others to know about
  • Lessons
      • Everything takes time, but you need to keep trying
      • Never give up even on things that seem impossible
      • It is okay to ask people for help
  • Any challenges
      • Sometimes it’s hard to figure some of the codes out and they do not always work right away

My MAGICal Experience

For the midpoint check, this slide can be left blank.

My Demo

  • When getting to the first page of what I have created there are 3 buttons on the start page: a learn more, start and exit button.When going onto the learn more page a picture of a person comes up with different button each leading to another page discussing the specific gland you clicked the button by. When going onto the start page an instructions page comes up to teach you how to play the game. The end button located on the bottom of every page leads to the end of the game where a person can get his or her score.

For the midpoint check, this slide can be left blank. But if a mentee wants to show whatever they have done so far, this is where to put it!

Google Doc

First Page

Learn More

Thyroid Page

Code

Question

Thank you!

Priva Halpert

10th Grade

My Mentor

  • Dr. Mindy Levine
  • Undergraduate and graduate education at Columbia University; major: chemistry
  • She did her postdoctoral fellowship in MIT.
  • Chemistry Professor since 2010.
  • Dr. Levine lives in Sharon, Massachusetts, and teaches chemistry in the University of Rhode Island.
  • Dr Levine is now planning to make aliyah to Israel.

My Project

Alcohol Detection Using Image Analysis and Color Changing Methods (squarine and BODIPY dye)

In what way will various alcohols react with nonpolar, highly colored dyes, particularly in the presence of cyclodextrin?

Introduction

  • The study I conducted this year was a more in depth and informative version of my study last year
  • The goal of this study was to develop an efficient system to detect alcohol in a given solution. Although there are other methods available in order to detect alcohol in a solution, they take a lot of time and often require expensive instruments, such as gas chromatography or liquid chromatography (Alves and Barros et. al., 2006; Phillips, 1983).

For midpoint check, the mentee can talk about how they selected their project, what the project is about, and how much progress they have made so far.

Introduction

  • Many bacterial organisms that are harmful to people can produce different types of alcohol when hosted in food, such as salmonella in pork, and E. coli in produce (Shimwell, 1950; Muller, 2001; Bunch, Clark and Dailly, 2000; Alterthum et. al. 1991)
  • Detection of pathogens prior to ingestion could help save lives as approximately 1.2 million people are infected with salmonella and 450 of these infected people die per year in the United States (Centers for Disease Control and Prevention, 2019)
  • This study focuses on alcohols commonly produced by bacterial organisms, as a way to detect these organisms through monitoring the presence of their alcohol byproducts.

For midpoint check, the mentee can talk about how they selected their project, what the project is about, and how much progress they have made so far.

System Developed

The system developed relies on the structural features of the alcohols, in order to cause a color change in the overall solution that contains a dye and cyclodextrin host. Alcohol molecules of this type have both a non-polar and a polar section of the molecule. As a result of these properties, one can cause the alcohol to bind in cyclodextrin molecule, which is a group of glucose molecules all linked together in a ring.

For midpoint check, the mentee can talk about how they selected their project, what the project is about, and how much progress they have made so far.

When placed in a polar solvent such as water, the non-polar sections of the glucose group together to form a ring-shaped figure, in which the center is nonpolar and the outside is polar. When the water, alcohol and cyclodextrin are combined in a solution the alcohol positions its non-polar section within the center of the cyclodextrin ring, which is nonpolar, and the polar part of the alcohol sticks out into the polar water environment.

System Developed

Adding a nonpolar dye (sanguine and BODIPY- boron-dipyrromethene)to a solution with cyclodextrin causes a color change in the dye, because the dye is attracted to the inside of the ring and positions itself there. After adding the alcohol, the dye is kicked out of the ring in order to make room for the alcohol. This change in the molecular environment of the dye causes the solution to appear to be a different shade than before.

System Developed

Ethyl Alcohol

n-Butyl Alcohol

Isopropyl

Alcohol

2-hydroxypropyl-β-cyclodextrin

Boron-based dye

(BODIPY)

Squaraine dye

Molecule Modeling

Molecule Modeling

BODIPY in alpha cyclodextrin

BODIPY in beta cyclodextrin

BODIPY in gamma cyclodextrin

NOTE: in this study beta cyclodextrin was used

Image Analysis

1- isopropyl with cyclodextrin

3- n-butyl

3- n-butyl with cyclodextrin

2- ethyl

2- ethyl with cyclodextrin

1- isopropyl

WATER VALUES (CD)- CONTROL VERSUS ALCOHOL VALUES (CD)

anlyte

R

G

B

H

S

L

1: isopropyl

183.00

170.00

15.00

55.00

85.00

39.00

2: ethyl

161.00

164.00

3.00

61.00

96.00

33.00

3: n-butyl

176.00

188.00

23.00

64.00

78.00

41.00

4: water

170.0000

169.0000

167.0000

40.0000

2.0000

66.0000

Data

Comparison of the separate analytes

COMPARISON OF CD v noCD ON RGB PER ANALYTE

Data

Comparison of the separate analytes

Data

Comparison each analyte CD v noCD

COMPARISON OF THE ANALYTES (CD AND noCD SEPARATELY COMPARED)

As can be seen in the data obtained through this study, there is a significant difference between the effects of the addition of cyclodextrin to various alcoholic analytes, as well as a significant difference between the analytes themselves with cyclodextrin and without. Therefore my hypothesis was supported by the findings of this study. This new data can be used for various purposes, including but not limited to alcoholic testing, bacterial testing and health screening.

This study was very helpful in determining and analyzing the different interactions between alcohols and various other substances. In conclusion, we found that alcohols are very receptive to color change. There was not a very large difference between the solutions containing cyclodextrin as opposed to those without, although there was a significant difference between the interactions of the different alcohols and dyes. This technique can be used to determine what alcohol exists within a solution, as well as its concentration.

Conclusion

Thank you!

Eliana Millstone

12th Grade

My Mentor

  • Yan Guan
    • She works as a Key Account Technologist in Lam Research Crop. in Freshmont, CA
    • She is originally from China, but moved to the US in 1998 to attend graduate school
    • She loves reading self improvement books, an enjoys ski and snowboarding, running,and bodybuilding workouts
    • She has two kids: a 16 year old son and a 14 year old daughter

Website

First Page

Website

Statistics

Website

Photo Gallery

Introduction

  • A fuel cell is a device which converts chemical energy into electrical energy
  • In a proton exchange membrane fuel cell (PEMFC) the fuel source is water
    • Benefits: no pollution and fewer breakdown
  • Electrolysis is when water is broken down into its components, hydrogen and oxygen
  • Fuel cell has 5 major components: the anode, 2 catalyst layers, an electrolyte layer and the cathode
  • Steps:
    • Fuel enters the anode. Then the hydrogen gas reacts with the catalyzed layer ionizes, and then dissociates
      • 2H2→4H++4e−
    • The hydrogen ions move into the cathode, and then move out of the fuel cell and are used to power various power sources
    • At the same time, oxygen is entering the cathode to form the following reaction
      • O2+4e−+4H+→2H2O

My Project

  • Project name: Hydro Car
  • Objective: investigate how a fuel cell works and determine its efficiency using the Fuel Cell Car FCJJ-11
  • Why I chose this project: I chose this project because I think fuel cells are the future and the whole topic fascinates me
  • What I learnt from this: I learnt a lot about alternative energy sources
  • Achievements: set up the car, test a whole range of times to find the optimal amount of time to charge the water for, and testing the difference in voltage between using a battery and using solar panels.
  • Future research: improvement of solar panels

My Results

Time spent charging (min)

Time it ran for (sec)

1

32

2

59

5

142

10

287

My Results

Round #

How long solar panel runs for (sec)

How long battery runs for (sec)

1

112

142

2

107

135

3

99

151

4

103

139

Charged the water with either the solar panel or battery for 5 minutes.

Videos

Charging the water

Car running

  • Highlights:
    • I get to be very hand on with a particular engineering field which extremely interests me.
    • I also got an opportunity to create a website which will attempt to persuade people to become more interested in this field of engineering
  • Lessons learnt
    • I learnt a lot about the complexity of running cars on water. We need an alternate energy source to charge the water
    • I also learnt how to independently perform research

My MAGICal Experience

Thank you!

MAGIC-Mentee-Presentation 2018-19 (SKA) - Google Slides