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Cuvette journal club

29/08/23

The Good, the bad and the ugly of a short academic career

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Who am I?

Associate Director

Creator, exec producer & host

Founder & community manager

Scientist

Science communicator/writer

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Science me

BSc Biomedical Science 2010-2013

Mres Immunobiology 2014-2015

PhD 2015-2019

Macrophage heterogeneity in Drosophila melanogaster

IL-1α in arthrofibrosis pathogenesis

Post-doc 2019-2020

CD8 T cell responses (transcriptional, proteomic and epigenetic) to hypoxia

Post-doc research associate

(Hughes Hall)

Ncl

Shf

Cam

Cam

Ldn

Post-doc 2020-2023

Neutrophil trafficking to IRI and neutrophil-T-cell interactions

ASAPbio 2023-

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Interleukins, prostaglandins and lots of RNA

First “real” research project

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Uncovering heterogeneity in Drosophila macrophages reveals subpopulations with enhanced inflammatory responses to injury

A several nations army

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Hypoxia in T cells & a suffocating, toxic environment

The no-good, bad and the ugly

Started March 2019

PhD student Oct 2019

PhD student quit Feb 2020

Complaint Feb/March 2020

I quit August 2020

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Essential, missing and difficult

Community

In response to the difficulties I witnessed and experienced I founded a community for postdocs

Inspired by Prachee Avasthi & new PI slack

>400 members BUT….. Many lessons learned during this

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Neutrophil-T cell interactions during ischemia reperfusion injury

Cross-talk & testicles

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Preprints, metascience and a new path

A pandemic & a change

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Time for a career change!

Openness & a push

£5000

~£500,000

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BSc Biomedical Science 2010-2013

Mres Immunobiology 2014-2015

PhD 2015-2019

Macrophage heterogeneity in Drosophila melanogaster

IL-1α in arthrofibrosis pathogenesis

Post-doc 2019-2020

CD8 T cell responses (transcriptional, proteomic and epigenetic) to hypoxia

Post-doc research associate

(Hughes Hall)

Post-doc 2020-2023

Neutrophil trafficking to IRI and neutrophil-T-cell interactions

ASAPbio 2023-

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Diverging paths

Academia

Preprints, research culture, ???

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Me & preprints

2019

2020

2021

Preprints

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Currently

Still a scientist but now I get paid appropriately, don’t deal with the downsides and have spare time/hobbies again!