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Predicted Effector Gene Working Group: June 2025

Julie Jurgens

Broad Institute of MIT and Harvard

6/5/25

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Agenda

  • Working Group Roadmap: ASHG & Beyond (Julie Jurgens)
  • Data Content Standards (Aoife McMahon)
  • Assigning Benchmarking Activity (Yue Ji & Noel Burtt)�

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2025 Roadmap: PEG Matrix Activities

June

July

August

September

October

ASHG (Boston)

10/14-10/18

Ancillary Session

WG Meeting:

Review Metadata

Content Benchmarking

WG Meeting:

Review Data

Content Benchmarking

WG Meeting:

Metadata Content

WG Meeting:

Data Content

Data Content Benchmarking

(Ends 2 wks before August WG)

Metadata Content Benchmarking

(Ends 2 wks before Sept. WG)

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Beyond ASHG

1. Publication

2. PEGathon- event to encourage the community to contribute their data using the new standards

3. Develop AI-assisted user upload system for PEG matrices

4. Convert existing lists to the new format using the tool

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Engage with professional societies to develop endorsed recommendations

Public pilot launch: Coordinated community efforts to identify new datasets and apply standards

Develop iterative versions of framework

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We need your help

Monthly WG meetings

Benchmarking activities

ASHG ancillary session

  • The community has a strong interest and need for PEG list standards
  • We need an engaged community of multidisciplinary experts
    • YOU!

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Planning our next WG meeting

  • July 2025
  • Doodle poll:

https://doodle.com/group-poll/participate/epLDm11e

  • Topic: Metadata content

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