975
Eligible patients
Excluded:
5 patients with X
10 patients with Y
10 patients without Z
Pour éviter les problèmes:
Lignes verticales = flèches « droites »
Lignes horizontales = flèches « coudées »
Excluded:
10 patients with missing data on X
1000
Patients aged 18-80 years
alive on January 1, 2022
975
Eligible patients
Excluded:
5 patients with X
10 patients with Y
10 patients without Z
965
Patients included at baseline
Excluded from longitudinal analyses:
100 patients lost from follow-up
100 patients died
765
Patients included in�longitudinal analyses
Excluded:
10 patients with missing data on X
1000
Patients aged 18-80 years
alive on January 1, 2022
975
Eligible patients
Excluded:
5 patients with X
10 patients with Y
10 patients without Z
965
Patients included at baseline
Excluded from longitudinal analyses:
100 patients lost from follow-up
100 patients died
765
Patients included in�longitudinal analyses
Excluded:
10 patients with missing data on X
1000
Patients aged 18-80 years
alive on January 1, 2022
975
Eligible patients
Excluded:
5 patients with X
10 patients with Y
10 patients without Z
965
Patients included at baseline
Excluded from longitudinal analyses:
100 patients lost from follow-up
100 patients died
765
Patients included in�longitudinal analyses
Excluded:
10 patients with missing data on X
1000
Patients aged 18-80 years
alive on January 1, 2022
975
Eligible patients
Excluded:
5 patients with X
10 patients with Y
10 patients without Z
965
Patients included at baseline
Excluded from longitudinal analyses:
100 patients lost from follow-up
100 patients died
765
Patients included in�longitudinal analyses
3500 Individuals (≥18 years) living in city Z
on 1 January 2015
3450 Individuals were potentially eligible
3410 Individuals were included in the analysis
50 Did not meet the eligibility criteria
10 Reason 1
20 Reason 2
20 Reason 3
40 Excluded from the analysis
40 Reason for exclusion
1136 With variable X = 1
1137 With variable X = 2
1137 With variable X = 3
3500 Individuals (≥18 years) living in city Z
on 1 January 2015
3450 Individuals were potentially eligible
3410 Individuals were included in the analysis
50 Did not meet the eligibility criteria
10 Reason 1
20 Reason 2
20 Reason 3
40 Excluded from the analysis
40 Reason for exclusion
1136 With variable X = 1
1137 With variable X = 2
1137 With variable X = 3
3500 Individuals (≥18 years) living in city Z
on 1 January 2015
3450 Individuals were potentially eligible
3410 Individuals were included in the analysis
50 Did not meet the eligibility criteria
10 Reason 1
20 Reason 2
20 Reason 3
40 Excluded from the analysis
40 Reason for exclusion
N= 1705�Intervention group
N= 1705�Control group
3500 Individuals (≥18 years) living in city Z
on 1 January 2015
3450 Individuals were potentially eligible
3410 Individuals were included in the analysis
50 Did not meet the eligibility criteria
10 Reason 1
20 Reason 2
20 Reason 3
40 Excluded from the analysis
40 Reason for exclusion
N= 1705�Intervention group
N= 1705�Control group
3500 Individuals (≥18 years) living in city Z
on 1 January 2015
3450 Individuals were potentially eligible
3410 Individuals were included in the analysis
50 Did not meet the eligibility criteria
10 Reason 1
20 Reason 2
20 Reason 3
40 Excluded from the analysis
40 Reason for exclusion
N= 1705�Intervention group
N= 1705�Control group
100 Patients assessed for eligibility
50 Randomized
50 Excluded
10 Did not meet inclusion criteria
20 Declined to participate
20 Other reasons…
N= 25�Allocated to treatment A
N= 25�Allocated to treatment B
N= 23�Received treatment A
N= 24�Received reatment B
N= 22 with follow-up data
(1 lost to follow-up)
N= 22 with follow-up data
(2 lost to follow-up)
100 Patients assessed for eligibility
50 Randomized
50 Excluded
10 Did not meet inclusion criteria
20 Declined to participate
20 Other reasons…
N= 25�Allocated to treatment A
N= 25�Allocated to treatment B
N= 23�Received treatment A
N= 24�Received reatment B
N= 22 with follow-up data
(1 lost to follow-up)
N= 22 with follow-up data
(2 lost to follow-up)