AI in Healthcare: NYU Langone Perspective �Yin Aphinyanaphongs MD/ PhD�2026-04-23�Hunter AI Day��
NYU Langone Health
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Vocabulary
State of AI
Generative AI
Generative AI – Images and Text (a.k.a. ChatGPT)
Joke from https://arxiv.org/pdf/2204.02311v2
AI at NYU Langone
MCIT Department of Health Informatics: �Division of Applied AI Technology
Develop, translate, evaluate, apply, train the workforce in artificial intelligence, machine learning, and predictive analytic solutions in support our corporate, clinical, research, and education missions.
Mission
Statement
NYULH Vision – AI and Generative Models
Using AI and Generative AI ethically and equitably at scale to improve: efficiency, quality and safety.
We believe that:
Efficiency
Quality
Safety
Generative AI Innovation and Progress
AI + GenAI Models Currently Live (Homegrown + Vendor) | AI + GenAI Models in Development (Homegrown + Vendor) |
128 Models | 153 Projects |
$ - Jiang, L.Y., Liu, X.C., Nejatian, N.P. et al. Health system-scale language models are all-purpose prediction engines. Nature 619, 357–362 (2023).
% - Small WR, Malhotra K, Major VJ, et al. The First Generative AI Prompt-A-Thon in Healthcare: A Novel Approach to Workforce Engagement with a Private Instance of ChatGPT. PLOS Digit Health. 2024 Jul 23;3(7):e0000394.
UltraVioletAI
Secure, HIPAA compliant Available to All 50,000 employees.
Launched October 1.
Deployed: 45k Windows devices, 3.7k Mac devices, and 12.5k smartphones
Unique Users: 19,601
New Chats Per Day: ~4,000
Mobile
Mobile
Epic View
Desktop
Confidential – Do Not Distribute
Use Case 1
Early Predictions of Skilled Nursing Facility Discharges To Accelerate Discharge Planning
Objective: Integrate early predictions of inpatient discharges to skilled nursing facilities (SNFs) into Epic to facilitate discharge planning and PT/OT resource triaging.
*Model: Language model (nyutron) predicts SNF discharge risk from AI summaries of H&P notes.
EHR Intervention: Patient list column describing SNF risk as "High", "Intermediate" or "Low". �Hover bubble displays AI summaries of H&P note that provide end-users with relevant context.
Enhancing the prediction of hospital discharge disposition with extraction-based language model classification. �Small, W.R., Crowley, R.J., Pariente, C., Eaton K, Jiang L, Oermann E, Aphinyanaphongs Y. npj Health Syst. 3, 4 (2026). https://www.nature.com/articles/s44401-025-00059-8#citeas
Epic Integration: AI Predictions of Skilled Nursing Facility Discharges from Clinical Documentation
1
2
3
Running in batch mode every morning on 18,000 patients.
Use Case 2
What defines a quality note? The 5Cs��
20
“C” | Description |
COMPLETE | Does this note contain an appropriate history, physical examination, and plan? |
CLINICAL ASSESSMENT & REASONING | Does this note contain a differential diagnosis OR a commitment to a clear diagnosis with a trajectory on how the patient is doing? |
CONTINGENCY PLANNING | Does this note contain an articulation of what milestone must be fulfilled to change management or Fulfill a discharge? |
CONCISE | Does this note contain only pertinent data/information? |
CORRECT | Is this note internally consistent AND free of critical deficiencies? |
Powerful Dashboard Promotes Transparency��
Use Case 3
More Use Cases!
GPT to classify in Immunosuppressant Reconciliation (Collaboration with Dr. Paawan Punjabi)
Clinical Scenario | Verbiage | Intent to Order today? | Alert Provider if Order NOT placed. |
55 y/o M w cirrhosis who underwent liver transplant | "Cellcept 1000 mg BID IV starting today" | Yes | Yes |
48 y/o M w Acute Lymphatic Leukemia presents for Bone Marrow Transplant | “Tacrolimus Start Day +5” | No | No (intent is future state) |
14 y/o with new-onset AKI | "Should she have proliferative lupus nephritis I would add...CellCept" | No | No (intent is conditional) |
Order today: NO
Do not alert clinician.
Classify the intent of verbiage in a clinical note as to whether the medication will be ordered today.
17 fires between 1/3 to 2/3 for any immunosuppressant across the system.
Physician Ambient Documentation: Abridge
�Why are we investing in Abridge?
Goal: 1,000 providers using Abridge by December 2025
Active Physicians by Month
July 2025
August 2025
September 2025
October 2025
Confidential – Do Not Distribute
Patient Digital Experience – Patient Friendly Discharge Summary Pilot (Colloboration with Dr. Feldman, Dr. Zaretsky)
Case timeline
High risk
"likely"
High risk
"definitely"
AI monitoring and summarizing from real-time ED data
Safety & Quality - ED High Risk Copilot: The alert starts a conversation (Colloboration with Dr. Genes, Dr. Simon, Dr. Femia)
Candidate Conditions:
Summarization – ED visit summaries for post-visit calls (Collaboration with Dr. Major and Dr. Silberlust)
ED patients receive a phone call after their visit. It takes the nurses a few minutes to review each chart to prepare.
Quality – Communicating ED Incidental Findings (Collaboration with Dr. Kar-mun Woo, Dr. Greg Simon)
Existing: Prioritizing high-risk messages to Physicians for fastest review (Collaboration with Dr. Major, Dr. Austrian).
Hi Dr xxx., xxx has been fussy for the past two days. She’s been crying almost every hour. She has no fever though. We tried giving her gripe water, which usually works but this time her crying is non-stop. We also noticed her cry has changed with episodes like she’s gasping for air. This is the first time we’ve noticed this. Should we take her to the ER at this point?
Model score: 78.98
RN called – Advised to go to ER
Subject: Fussiness
Patient age: 3 months
Prioritizing clinically concerning, high-acuity Epic InBasket messages
Efficiency – Speeding Connection with Physicians (Dr. Szerencsy)
Confidential – Do Not Distribute
Patient #3 scheduled for surgery on 7/17, required cardiac clearance, saw the cardiologist, BUT GPT detects no documentation of clearance, escalate. (Dr. McKeever)
Surgery Details
All appointments in last 90 days
'.Chief Complaint and History of Present Illness: Ms. X is a 42 y.o. female who comes for a follow up visit to discuss test results.Patient is a 42 year old woman non-smoker with h/o Printzmetal angina. CCTA showed no CADStarted using Norvasc 2.5mg po daily. No episodes of CP since. However, does note occasional episodes of low BP.S/p echo and ETT
Assessment / Plan: Diagnosis1. Other chest pain: ETT is WNL. Started amlodipine 2.5 mg daily. No more CP since. However, does note occasional episodes of low BP. Can take 1/2 tab if needed if SBP<110-refer to GI to r/o esophageal spasm as the cause for CP2. SOB (shortness of breath) on exertion : 2D echo shows normal LVEF, no significant valvular disease. She has gained some weight recently. Advised to exercise daily3. Mixed hyperlipidemia :Low fat diet and regular walk daily.4. Overweight 5. Primary insomnia 6. Hypothyroidism due to medication: She is on replacement therapy.
Tests Ordered This Visit:No orders of the defined types were placed in this encounter. Medications Ordered This Visit: Patient was made aware of her medical status; all questions, concerns and alternatives were outlined and discussed in details; patient was informed about risks and outcomes of untreated conditions or poor compliance.Special instructions, diet, exercise, weight control and plan of care were discussed with patient who verbalized his/her understanding and agreed with above. CQM CMS 69 / NQF 0421 - Adult BMI Screening and Follow Up: The patient\'s BMI is above normal. Counseled patient regarding BMI, healthy eating, portion control and exercise importance of diet to maintain a healthy weight.Compliance adherence was discussed [ x ] Risks of refusing the recommended test/treatment that include but not limited to death, life threatening 5 arrhythmia, stroke, heart attack, limb gangrene and amputation were outlined to the patient. Patient understands. Return in about 6 months (around 12/24/2024). Patient seen and evaluated with PA-Milana Bubis Tariq Jamil, MDAssistant professor of medicine/cardiology at NYUBoard certified in cardiology, nuclear cardiology, echocardiography and RPVI.
Thank You!�yin.a@nyulangone.org