IMAG/MSM Working Group on Multiscale Modeling and Viral Pandemics Mini Seminars
Jan 13, 2022
Welcome - The meeting will start at 3PM ET
NOTE: THE MEETING WILL BE RECORDED, STREAMED AND PUBLICLY AVAILABLE�FOR THOSE MEMBERS UNABLE TO ATTEND
Agenda
People
Co-Lead: Reinhard Laubenbacher, PhD
Department of Medicine
Laboratory for Systems Medicine
University of Florida
reinhard.laubenbacher@medicine.ufl.edu
Co-Lead: James A. Glazier, PhD
Dept. of Intelligent Systems Engineering and Biocomplexity Institute
Indiana University, Bloomington
Web Administration, Slack: James P. Sluka, PhD
Dept. of Intelligent Systems Engineering and Biocomplexity Institute
Indiana University, Bloomington
Activities Coordination: Bruce G. Shapiro, PhD, PMP
Laboratory for Systems Medicine
University of Florida
bruce.shapiro@medicine.ufl.edu
Slack Channel
https://Msm-working-group.slack.com
Our IMAG/MSM Wiki page
https://www.imagwiki.nibib.nih.gov/working-groups/multiscale-modeling-and-viral-pandemics Feel free to suggest additional content!
Or, use the Tiny URL: https://tinyurl.com/hkr97vfe
IMAG’s LinkedIn
YouTube “MSM Working Group on Multiscale Modeling” https://www.youtube.com/channel/UCuDFvhgFziRRDcpRnT3vlrw
Please follow the�group on Twitter!
If you could re-tweet the weekly announcements �(there are usually two, one for each speaker) �that would help boost attendance and community awareness.
Announcements
�Any short (~1 minute) items such as;
Schedule for Upcoming Meetings and mini-Seminars
Jan 20:
Jan 27:
Request for future speakers (Jan 13, …)
Rules of the Meeting
Please mute your microphone and hold questions until after the presentations
Mini-Seminar�Multiscale modeling of Human Physiology
Robert Hester�University of Mississippi Medical Center
HumMod is a model of human physiology comprising over 9000 dependent variables, and over 1500 independent parameters. It spans all major body systems, including circulatory, renal, respiratory, hepatic, gastrointestinal, neural, endocrine and muscular systems. Each system is built on one or more working hypotheses/models developed in the literature with reasonable support. These systems combine multiple tissues and their responses to hormones, metabolites, and physical forces. In the laboratory, such responses are considered under controlled circumstances. In the model, the simple mechanisms are tied together to produce feedback loops approximating the body’s own responses to physiological challenges. Current projects include: 1) simulations to understand how medical devices work and 2) simulating virtual populations for in silico clinical trials.
Requests for Input/Suggestions
We would like the subgroup leads to prepare brief presentations for the Thursday meetings, please let us know when you would like to present
Ideas/help for publicising our Thursday mini-seminars more effectively and for speakers to invite
Suggestions for agenda items and approaches to organizing the Steering Committee Meetings more effectively
There have also been a number of requests for more explicit statements of goals and tasks from the WG leadership, we would appreciate your suggestions
Please contact Reinhard Laubenbacher, James Glazier, James Sluka or Bruce Shapiro with your ideas on all of these issues
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