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INTRODUCTION

Bioproduction of the compound 3-n-butylphthalide (NBP)

Final Project

Paúl Romero, Ecuador

Openbioscience Ottawa Node

NBP Compound and Its Biosynthesis in Plants

Ligusticum chuanxiong

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Chemical Structure of NBP

NBP Biosynthetic Pathway

NBP Production Methods

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Bioproduction of the compound 3-n-butylphthalide (NBP)

BACKGROUND

Final Project

Paúl Romero, Ecuador

Openbioscience Ottawa Node

Global incidence of hypertension

(1990-2019)

National incidence of hypertension

(2021)

From 650 million to 1.3 billion

19.8% of the adult population

World Health Organization (WHO)

Pan American Health Organization (PAHO)

Therapeutic Limitations of Antihypertensive Drugs

Causes of deaths worldwide attributed to increased blood pressure in 2015

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Bioproduction of the compound 3-n-butylphthalide (NBP)

METHODOLOGY

Aim 1

Aim 2

Openbioscience Ottawa Node

Paúl Romero, Ecuador

Final Project

Aim 3