“I don't want to achieve immortality by being inducted into the Hall of Fame. I want to achieve immortality by not dying.”—William De Morgan

“Getting older is no problem. You just have to live long enough.”—Groucho Marx

“Man was made for immortality.”—Abraham Lincoln

“Get busy living or get busy dying.”—Steven King

“I’m not afraid of dying; I just don’t want to be there when it happens.”—Woody Allen�

Some Background

The State of the Science

The Questions

Discussion

Telomeres are not, in themselves, the holy grail of life extension.

Other issues: senescent cells, cell loss, sarcopenia, nuclear DNA mutations, mitochondrial DNA mutations, intra and extra-cellular “garbage“ accumulation and other factors.

Bring on the mice

TAME trials, XPrize

“Immortality”

Cryonics

Billionaires and public perception

Foresight Blindness: what are the implications?

How does one maintain meaning in a greatly extended lifespan of 150 to 200 or more years?

What happens to work and retirement? ( What happens in a split society where some opt out or don’t have access due to location or cost)

What happens to relationships? (E.G., can a marriage last for a century or more?)

What other questions should we be asking?

How long would you like to live and how would you maintain meaning and your sense of purpose?

“More than half of Americans (54%) say it is their goal to live to 100,”—joint press release from Corebridge Financial and The Longevity Project.”

“..the increasingly blurring boundaries of traditional daily life activities are reinforcing a long-term decline in formal paid work that has been [slowly] underway for decades.”—Andy Hines

“The trouble with retirement is you never get a day off.”—Abe Lemons

“Retirement at 65 is ridiculous. When I was 65 I still had pimples.”—George Burns

“A successful marriage requires falling in love many times, always with the same person.”—Mignon McGlaughlin

“Marriage is neither heaven nor hell, it is simply purgatory.”—Abraham Lincoln

“If you want to sacrifice the admiration of many men for the criticism of one, go ahead, get married.”—Katherine Hepburn

“Marriage is a wonderful institution, but who wants to live in an institurion.”—Grouch Marx

Why?

How would you maintain purpose in a radically longer lifespan?

How would you deal with a world where most of the friends and family you grew up with were gone?