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THERMOREGULATION

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A.) Introduction

1. Thermoregulation is the maintenance of body temperature within a range that homeostasis

2. It may involve both behavioral and physiological adaptations.

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3 ways heat is gained:

A.) Mechanisms that transfer heat

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4 ways heat is lost:

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Endotherms

Are animals that derive body temperature from internal heat production.

Ectotherms

Are animals that derives body temperature from an external heat source.

B.) Sources of Heat

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Poikilotherm (poikilo =“varied”) - body temperature approximates the ambient temperature. Not capable of controlling body temperature as ambient temperature varies. What is the adaptive advantage here?

Heterotherm (hetero = “different”) - regulates body temperature when active, but allows body temperature to fluctuate with the environment when inactive.

Homeotherm (homeo = “same”) - controls body temperature, keeping it relatively constant as ambient temperature varies.

These terms relate to whether or not the animal is capable of controlling body temperature.

Describe the advantage to temperature homeostasis from the fact that animal bodies are made mostly of water.

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Body Temperature Regulation: Endotherm vs. Ectotherm

  • What anatomical & physiological

characteristics are common

among endotherms?

  • What other organ systems

are commonly well

developed in endotherms?

  • Are all ectothermic animals

correctly described as

“conformers”? Illustrate your answer with some examples.

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Lizard Behavioral Thermoregulation

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Behavioral and physiological mechanisms in Homeotherms

  • Relocation

  • Thermogenesis (generation of heat)
      • Shivering (generating heat with muscle activity)
      • Non-shivering (generating heat by metabolizing adipose (fat) tissue)

  • Vasoconstriction/vasodilation

  • Evaporative water loss

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Leg of a bird or mammal

Flipper of a seal or whale

Heat Exchange in Appendages

Which mechanism of heat transfer is operating here?

Cross-section:

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Control of Conductance by

Regional Heterothermy

Cold-climate homeotherms can allow their appendages to cool to reduce heat loss.

Countercurrent heat exchange occurs between warm out-flowing blood in a central artery and cold in-flowing blood in surrounding veins.

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Integumentary System in Thermoregulation

Organs of thermoregulation in the skin:

  • sweat glands
  • arrector pili muscle
  • vasodilation/vasoconstriction

Why are there both cold and hot thermoreceptors in the body?

What organ serves as the control center to regulate these organs?

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Temperature Homeostasis in Humans

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Temperature Acclimatization

  • Molecular mechanisms
    • Make more enzymes (Why?)
    • Produce enzyme variants (Explain)
    • Alter cell membrane components (How?)
    • Produce cryoprotectants (“freeze tolerance”)
    • Produce stress-induced proteins
  • Behavioral mechanisms
    • Torpor
      • Hibernation (winter torpor)
      • Estivation (summer torpor)
      • Diurnal (daily, often nocturnal) torpor

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The Fluid Cell Membrane

How does the behavior of the cell membrane change with temperature?

How does the chemical make-up influence this behavior?

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Wood frog, Rana sylvatica�(glucose acts as a cryoprotectant)

Wood frog in summer

Wood frog, frozen

The “winter” frog is in cardiac arrest, & has 65% of its body water frozen.

If ECF water freezes, what would happen to ICF water?

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Heat-shock proteins protect and chaperone other proteins

  • Produced in response to various forms of stress: temp, hypoxia, pH, cancer, etc.

  • Protein clumps are seen in the neurons of patients with Mad Cow disease and Alzheimer’s disease.

What cell function may be faulty in these disease processes?

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I love old people.. so cute! Watch and listen to this CAREFULLY. It should make you feel smart. He makes connections to MANY things you learned this year!!!

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Learning Objectives

You should be able to answer these questions by Wednesday 3/25

  • Distinguish between the thermoregulators classified as endotherms and ectotherms, homeotherms, heterotherms, and poikilotherms

  • Describe the adaptive advantage(s) of endothermy

  • Discuss the 4 mechanisms utilized by land homeotherms to balance their heat budget

  • Discuss the roles of the hypothalamus in vertebrate temperature regulation

  • Compare and contrast some of the physiological mechanisms involved in acclimatization to new temperature ranges