From BRCA to Tay-Sachs:

The Modern Approach to Genetic Testing

​

Shari Ungerleider

Community and Education Manager

​

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Disclosures and Conflicts

• The presenter is employed by jscreen and receives compensation from that organization
• Neither the presenter nor jscreen is aware that this presentation presents a conflict of interest
• This presentation is informational and is not intended to provide medical advice

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Objectives:

• To understand the impact genetic diseases can have on a family
• jscreen’s process – Reproductive Carrier Screening and Hereditary Cancer Testing
• How jscreen can help individuals/couples and providers

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Our Mission

Our mission at jscreen™ is to transform the landscape of genetic health screening, one informed choice at a time. We believe that every individual deserves access to comprehensive genetic testing to inform reproductive health choices and an understanding of hereditary genetic risks. Through our innovative platform, we provide accessible and affordable testing, empowering individuals to make informed decisions that shape healthier futures. By fostering awareness, education, and proactive health management, we aim to make a meaningful impact on the lives of those we serve, redefining the standard of care and paving the way for a brighter, healthier tomorrow.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Reproductive Carrier Screen

• Panel of 265 genes, used for reproductive purposes
• For ages 18-45
• Women, men, any ethnic background
• Available in all 50 states

​

Hereditary Cancer Test

• Panel of more than 40 cancer susceptibility genes, covering many types of cancer
• For ages 21+
• Women, men, any ethnic background
• Available in all 50 states

​

CONFIDENTIAL: DO NOT DISTRIBUTE.

The Beginning of Population Screening

CONFIDENTIAL: DO NOT DISTRIBUTE.

Purpose of Carrier Screening�

Reproductive Carrier Screening :

an optional test* to learn about genetic conditions that may affect a pregnancy

jscreen’s Goal:

Easy access to genetic screening that provides information to families to support healthy pregnancy outcomes

* ideally before pregnancy

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

The jscreen process:

* jscreen uses a

third- party physician network for all orders

* DNAvisit

CONFIDENTIAL: DO NOT DISTRIBUTE.

How much will it cost? �$49 up front fee�and the rest is billed to your insurance�

• After you order has been processed, you will receive a personalized cost estimate from the testing laboratory.

​

• Many customers have $0 additional cost for testing, but insurance coverage varies and you may have out-of-pocket costs depending on your coverage.

​

• If your insurance does not pay for testing, you are uninsured, or you have a high deductible, you can forego insurance and directly pay $249 to the lab.

​

• If you cannot afford testing, there are financial assistance programs available for those who qualify.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

For 10 years, JScreen has built and honed best practices for the genomic screening journey

jscreen's Successful Model

Consent & intro to the process

History taking & sample collection

Sequencing interpreted

Genetic counseling & support

Initial contact & education

Virtual access in safety of home

Education

Testing made easy

Highest standards for test quality

Best practices - GC support throughout

Right TIME, Right TEST, Right WAY

We provide this entire service for ~$400/person presently

With a 99% customer satisfaction rate

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

How jscreen can help�

• jscreen provides access to preventative genetic testing and counseling for reproductive carrier screening and hereditary cancer testing without a wait.
• jscreen is for everyone – not just Jewish.

​

• If someone has religious or cultural concerns jscreen can address them.

​

• jscreen uses the latest form of technology through genetic sequencing.

​

• jscreen can provide education for your community.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Take Action. Take Control.

Impact the Health of Future Generations.

CONFIDENTIAL: DO NOT DISTRIBUTE.

• Assure there is accurate screening process in place with the HCP’s at your institution, which includes a referral process to a genetic counselor.

​

• Just because someone is Jewish they may not have been offered screening in the past. If they have it may not have been an expanded panel.

​

• Don’t rely on family history to determine the need for hereditary cancer testing.

​

• Educate medical professionals in your community about the importance of genetic testing.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Questions

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.

Shari Ungerleider

shari@jscreen.org

www.jscreen.org

CONFIDENTIAL: DO NOT DISTRIBUTE.

CONFIDENTIAL: DO NOT DISTRIBUTE.