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Hormones are not secreted at a uniform rate and exert their effect at low concentrations.

D5 Hormones and Metabolism

Essential Idea

Challenge: How many hormones can you list?

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D5 Hormones and Metabolism

Vocabulary

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D5 Hormones and Metabolism

D5.U1Endocrine glands secrete hormones directly into the bloodstream.

Gland

Hormones

Target Organ

Function

Pineal Gland

Melatonin

Many

Biological Clock

 Pituitary Gland

FSH, LH ADH, Oxytocin, Prolactin, Growth Hormone

 Ovaries, Kidneys, Breast Tissue

 Menstrual Cycle, Osmoregulation, Growth and Division, Contractions and Milk production

Adrenal Glands

 Adrenaline

Many

Fight or flight

 Thyroid Gland

Thyroxin

 Liver

 Metabolic Rate

 Pancreas

Insulin,Glucagon

 Liver

Blood Sugar Levels

 Testes

Testosterone

many

Male Characteristics

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�Metabolism (e.g. TSH activates thyroxin)�Adult Development  (e.g. LH / FSH trigger puberty)�Reproduction (e.g. LH / FSH control menstruation)�Growth (e.g. growth hormone promotes growth)�Equilibrium (e.g. ADH and water balance)

D5 Hormones and Metabolism

D5.U7 Hormones secreted by the pituitary control growth, developmental changes, reproduction and homeostasis.

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D5 Hormones and Metabolism

Steroid Hormone

Hormone Receptor

Hormone Receptor Complex

Cellular Response

Challenge: What examples can you think of?

Steroid hormones include those produced by the gonads (i.e. estrogen, progesterone and testosterone)

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D5 Hormones and Metabolism

Peptide Hormone

Receptor

Signal Transduction

Initiated indirectly by messengers

Challenge: What examples can you think of?

Peptide hormones include insulin, glucagon, leptin, ADH and oxytocin

cGMP is a common secondary messenger

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  • Prolactin is responsible for the development of the mammary glands and the production of milk
  • Oxytocin is responsible for release the of milk from the mammary glands (milk ejection reflex)
  • It is secreted by the anterior pituitary in response to the release of PRH (prolactin releasing hormone) from the hypothalamus
  • The effects of prolactin are inhibited by progesterone, which prevents milk production from occurring prior to birth

D5 Hormones and Metabolism

D5.A2 Control of milk secretion by oxytocin and prolactin.

Prolactin Milk Production

Oxytocin Milk Ejection

Positive Feedback

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D5 Hormones and Metabolism

D5.A1 Some athletes take growth hormones to build muscles.

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D5 Hormones and Metabolism

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