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� Hook Worm Diseases

Dr. Pallav Shekhar

Asstt. Professor

Veterinary Medicine

UNIT-6

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Bunostomiasis or Hook Worm Disease

  • This disease is characterized by emaciation, progressive anemia, constipation followed by diarrhea and death in young animals.

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Etiology

  • Cattle- Bunostomum phlebotomum

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  • Sheep and goat- B. trigonocephalum

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Epidemiology

  • The disease is world wide in occurrence and is more common in tropical countries.

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  • Calves in the age group of 4-12 months are commonly affected.

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  • The disease is transmitted mainly through skin penetration

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Life cycle-Direct

Egg

Feces

L1

L2

L3 stage infective

Cutaneous penetration

Enter in blood

Heart and lung

Alveoli

L4 stage

Pharynx

Swallowed

S.I

Penetrate Mucosa

Lumen of S.I

Adult worm

laying

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Pathogenesis

  • Active blood sucking are the major cause of anaemia in all species.
  • Total worm as low as 100 may cause clinical illness and 2000 may cause death in young cattle.
  • Hypoprotenemic oedema, bottle jaw and some irritation of intestinal mucosa leads to mild diarrhoea
  • Penetration of skin leads to irritation and itching.

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Clinical findings

  • Stamping and licking of feet.
  • Constipation accompanied by abdominal pain followed by bouts of diarrhoea.
  • Pale mucous membrane
  • Presence of occult blood in feces
  • Oedema of lower abdominal part

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Diagnosis

  • Identification of eggs in feces and coproculture are most detectable method of diagnosis.
  • Other methods like clinical symptoms like anaemia, diarrhoea and anasarca.
  • Necropsy is the only certain method of diagnosis i.e hook worms attached to the mucosa of small intestine and intestinal content are deeply blood stained.

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Treatment

  • BENZIMIDAZOLE EFFECTIVE AGAINST ADULT
  • AVERMECTIN BUNOSTOMUM Sp. Sheep & cattle
  • LEVAMIZOLE but are not effective against larval
  • MORANTEL larval stage

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  • NOTROXYNIL AND RAFOXANIDE ARE EFFECTIVE AGAINST IMMATURE WORM

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  • SUPPORTIVE TREATMENT LIKE HEMATINICS AND MINERAL MIXTURE CONTAINING FE, CU, CO ARE ESSENTIAL AS ANAEMIA IS THE MAIN CAUSE OF DEATH.

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Hook worm disease of dog and cat

Ancylostoma caninum

    • Characterized by poor growth and anaemia and are most widely distributed hook worm of pet and zoo animals.
    • All breeds and young ones are highly susceptible.
    • All breeds and young ones are highly susceptible

Ancylostoma brazilliensis

    • Found in S.I of dog, cat, leopard, foxes and human being

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Ancylostoma tubaeformis

    • Found in cats

A. duodenale

    • Found in man and also in dog and cats.

Nectar americanus

    • Common in man

Uncenaria stenocephala

    • Found in dog, act and foxes

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Transmission

By ingestion

By penetrating the skin

Transplacental

Transcolostral

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Pathogenesis

Adult worm

Egg

Hatch

Twice

L1 and L2 stage

L2

stage infective

Penetrate skin

blood

heart

lung

Larvae in lung capillaries

L3 development

L4 stage

Rupture capillaries

Enter into lung alveoli

Crowl in resp. tract

Cough up

Re-swallowed

intestine

Adult

Eggs

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Pathogenesis

L2 stage

Directly into G.I tract

Adult

Penetrate skin

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Colostrum

G.I. Tract

Placenta

Foetus

Prenatal infection

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Cont…..

  • Migratory larvae doesn’t cause much damage.

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  • Adult parasites are harmful as they are active suckers and cause severe anaemia and also haemorrhage in intestine.

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Clinical Findings

  • Severe anaemia and sudden death in acute condition.

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  • In moderate condition , pale mm, anaemia, emaciation, stunted growth, mild diarrhoea, melena and itching of skin.

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  • Red bite mark in the lower abdominal region.

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Diagnosis

Diagnosis- Fecal examination

D/D- Leptospirosis

Coccidiosis

Canine Babesiosis

Canine Ehrlichosis

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Treatment

Mebendazole-22mg/kg daily orally for 5 days

Pyrantel- 6-15mg/kg commonly in human beings

Albendazole- 25mg/kg for 3 consecutive days

Supportive Medicine- Blood transfusion, hematinic.