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DUMES Respiratory Revision

Friday Q&A Session

14th August 2020

Contributors:

Olivia Allatt

Lucy Gold

Julia Manini

Nitya Nair

Ross Wilson

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1. Select the correct classification for each of the following joints:

  1. Coronal suture
  2. Sternoclavicular joint
  3. Elbow joint

  1. Fibrous joint
  2. Primary cartilaginous joint
  3. Secondary cartilaginous joint
  4. Pivot type synovial joint
  5. Hinge type synovial joint
  6. Saddle type synovial joint

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1. Select the correct classification for each of the following joints:

  1. Coronal suture
  2. Sternoclavicular joint
  3. Elbow joint

  1. Fibrous joint
  2. Primary cartilaginous joint
  3. Secondary cartilaginous joint
  4. Pivot type synovial joint
  5. Hinge type synovial joint
  6. Saddle type synovial joint

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2. Select the correct classification for each of the following joints:

  1. Interosseous membrane of the forearm
  2. Pubic symphysis
  3. Intervertebral disc

  1. Fibrous joint
  2. Primary cartilaginous joint
  3. Secondary cartilaginous joint
  4. Pivot type synovial joint
  5. Hinge type synovial joint
  6. Saddle type synovial joint

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2. Select the correct classification for each of the following joints:

  1. Interosseous membrane of the forearm
  2. Pubic symphysis
  3. Intervertebral disc

  1. Fibrous joint
  2. Primary cartilaginous joint
  3. Secondary cartilaginous joint
  4. Pivot type synovial joint
  5. Hinge type synovial joint
  6. Saddle type synovial joint

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3. Identify the correct cell types based on the following descriptions of their function:

  1. Secrete mucins to immobilise pathogens and foreign bodies in the respiratory tract
  2. Secrete glycosaminoglycans which protect the epithelial lining of bronchioles
  3. Secrete pulmonary surfactant, a fluid which opposes alveolar surface tension

  1. Type I pneumocyte e. Goblet cell
  2. Type II pneumocyte f. Alveolar macrophage
  3. Type III pneumocyte g. Cup cell
  4. Club cell h. Mast cell

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3. Identify the correct cell types based on the following descriptions of their function:

  1. Secrete mucins to immobilise pathogens and foreign bodies in the respiratory tract
  2. Secrete glycosaminoglycans which protect the epithelial lining of bronchioles
  3. Secrete pulmonary surfactant, a fluid which opposes alveolar surface tension

  1. Type I pneumocyte e. Goblet cell
  2. Type II pneumocyte f. Alveolar macrophage
  3. Type III pneumocyte g. Cup cell
  4. Club cell (Clara cell) h. Mast cell

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4. Select the correct associations for each of the following anatomical landmarks:

  1. Bifurcation of the trachea
  2. Sternal angle
  3. Male nipple

  1. T4 d. 2nd rib
  2. T4/5 e. 3rd rib
  3. T5 f. 4th rib

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4. Select the correct associations for each of the following anatomical landmarks:

  1. Bifurcation of the trachea
  2. Sternal angle
  3. Male nipple

  1. T4 d. 2nd rib
  2. T4/5 e. 3rd rib
  3. T5 f. 4th rib

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5. Respiratory epithelium goes by which histological name …?

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5. Respiratory epithelium goes by which histological name …?

Pseudostratified columnar epithelium with Goblet cells

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6. Select the nerve which serves each of the following functions in the cough reflex:

  1. Supplies mechanoreceptors to the upper respiratory tract
  2. Controls contraction of the diaphragm during the inspiratory phase
  3. Controls contraction and relaxation of its respective intercostal muscle

  1. Long thoracic nerve e. Phrenic nerve
  2. Short thoracic nerve f. Vagus nerve (CN X)
  3. Intercostal nerve g. Spinal accessory nerve (CN XI)
  4. Subcostal nerve h. Hypoglossal nerve (CN XIII)

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6. Select the nerve which serves each of the following functions in the cough reflex:

  1. Supplies mechanoreceptors to the upper respiratory tract
  2. Controls contraction of the diaphragm during the inspiratory phase
  3. Controls contraction and relaxation of its respective intercostal muscle

  1. Long thoracic nerve e. Phrenic nerve
  2. Short thoracic nerve f. Vagus nerve (CN X)
  3. Intercostal nerve g. Spinal accessory nerve (CN XI)
  4. Subcostal nerve h. Hypoglossal nerve (CN XIII)

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7. Regarding the upper and lower respiratory tracts:

  1. Through which bifurcation of the trachea is aspirated material most likely to pass?
  2. In which space is pleural effusion first identifiable on a posteroanterior chest film?
  3. Which structure forms a barrier between the laryngopharynx and larynx to prevent aspiration?

  1. Left main bronchus e. Costodiaphragmatic recess
  2. Right main bronchus f. Caval hiatus
  3. Anterior mediastinum e. Epiglottis
  4. Posterior mediastinum h. Rima glottidis

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7. Regarding the upper and lower respiratory tracts:

  1. Through which bifurcation of the trachea is aspirated material most likely to pass?
  2. In which space is pleural effusion first identifiable on a posteroanterior chest film?
  3. Which structure forms a barrier between the laryngopharynx and larynx to prevent aspiration?

  1. Left main bronchus e. Costodiaphragmatic recess
  2. Right main bronchus f. Caval hiatus
  3. Anterior mediastinum e. Epiglottis
  4. Posterior mediastinum h. Rima glottidis

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8a. Regarding the upper and lower respiratory tracts:

A patient which a known lung tumour develops a left-sided Horner’s syndrome. Where is the causative lesion most likely to be found?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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8a. Regarding the upper and lower respiratory tracts:

A patient which a known lung tumour develops a left-sided Horner’s syndrome. Where is the causative lesion most likely to be found?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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8b. Regarding the upper and lower respiratory tracts:

A patient on the stroke unit has a compromised swallow. They later develop aspiration pneumonia. Where is aspiratory infiltrate most likely to be found?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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8b. Regarding the upper and lower respiratory tracts:

A patient on the stroke unit has a compromised swallow. They later develop aspiration pneumonia. Where is aspiratory infiltrate most likely to be found?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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8c. Regarding the upper and lower respiratory tracts:

A patient is treated in the accident and emergency department following a motorcycle accident. They are acutely breathless. Chest films reveal a left-sided rib fracture. Damage to which structure MUST be excluded during the diagnostic work-up?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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8c. Regarding the upper and lower respiratory tracts:

A patient is treated in the accident and emergency department following a motorcycle accident. They are acutely breathless. Chest films reveal a left-sided rib fracture. Damage to which structure MUST be excluded during the diagnostic work-up?

  1. Left upper lobe e. Right lower lobe
  2. Left lower lobe f. Lingula
  3. Right upper lobe g. Liver
  4. Right middle lobe h. Spleen

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9. A 56-year-old man is admitted to A&E with nausea, vomiting and severe abdominal pain. The patient was noted to be hyperventilating during the ambulance journey. He has a BMI of 32 and a past medical history of hypertension and type II diabetes. During the course of his treatment, an arterial blood gas (ABG) is obtained.

What is the MOST ACCURATE description of these findings?

pH = 7.20 (7.35 – 7.45)

PaCO2 = 23 (35 – 45)

[HCO3-] = 14 (22 – 26)

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What is the MOST ACCURATE description of these findings?

pH = 7.20 (7.35 – 7.45)

PaCO2 = 23 (35 – 45)

[HCO3-] = 14 (22 – 26)

  1. Uncompensated respiratory acidosis
  2. Respiratory acidosis with partial compensation
  3. Respiratory acidosis with full compensation
  4. Uncompensated metabolic acidosis
  5. Metabolic acidosis with partial compensation
  6. Metabolic acidosis with full compensation

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What is the MOST ACCURATE description of these findings?

pH = 7.20 (7.35 – 7.45)

PaCO2 = 23 (35 – 45)

[HCO3-] = 14 (22 – 26)

  1. Uncompensated respiratory acidosis
  2. Respiratory acidosis with partial compensation
  3. Respiratory acidosis with full compensation
  4. Uncompensated metabolic acidosis
  5. Metabolic acidosis with partial compensation
  6. Metabolic acidosis with full compensation

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10a. You are working in a humanitarian aid camp in a region of Asia recently struck by flooding. A 30-year-old woman attends clinic and appears severely dehydrated. She complains of copious watery, ‘rice-water’ stools.

Which organism is the likely cause of this woman’s symptoms?

  1. Campylobacter jejuni d. Vibrio cholerae
  2. Escherichia coli 0157 e. Staphylococcus aureus
  3. Bacillus cereus f. Helicobacter pylori

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10a. You are working in a humanitarian aid camp in a region of Asia recently struck by flooding. A 30-year-old woman attends clinic and appears severely dehydrated. She complains of copious watery, ‘rice-water’ stools.

Which organism is the likely cause of this woman’s symptoms?

  1. Campylobacter jejuni d. Vibrio cholerae
  2. Escherichia coli 0157 e. Staphylococcus aureus
  3. Bacillus cereus f. Helicobacter pylori

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10b. You are working in a humanitarian aid camp in a region of Asia recently struck by flooding. A 30-year-old woman attends clinic and appears severely dehydrated. She complains of copious watery, ‘rice-water’ stools.

If this patient were to have an ABG performed, what would be the MOST LIKELY biochemical abnormality?

  1. Mixed respiratory / metabolic acidosis
  2. No biochemical abnormality
  3. Respiratory acidosis e. Metabolic acidosis
  4. Respiratory alkalosis f. Metabolic alkalosis

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10b. You are working in a humanitarian aid camp in a region of Asia recently struck by flooding. A 30-year-old woman attends clinic and appears severely dehydrated. She complains of copious watery, ‘rice-water’ stools.

If this patient were to have an ABG performed, what would be the MOST LIKELY biochemical abnormality?

  1. Mixed respiratory / metabolic acidosis
  2. No biochemical abnormality
  3. Respiratory acidosis e. Metabolic acidosis
  4. Respiratory alkalosis f. Metabolic alkalosis

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11. A pulmonary embolus is suspected in a patient in the ICU. He is haemodynamically stable.

Which investigation is MOST USEFUL for the diagnosis of pulmonary embolus in this patient?

  1. Echocardiography
  2. CT pulmonary angiography
  3. 12 lead ECG
  4. Isotope lung scanning
  5. Blood D-dimers

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11. A pulmonary embolus is suspected in a patient in the ICU. He is haemodynamically stable.

Which investigation is MOST USEFUL for the diagnosis of pulmonary embolus in this patient?

  1. Echocardiography
  2. CT pulmonary angiography
  3. 12 lead ECG
  4. Isotope lung scanning
  5. Blood D-dimers

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12. A 35 year old obese female who had a surgery for breast cancer 2 weeks ago presents to the Emergency Department with severe pleuritic chest pain, shortness of breath and haemoptysis.

On examination: BP is 80/50 mmHg, heart rate is 130 bpm, she is cyanotic, respiratory rate is 30 and ABG shows Type 1 respiratory failure.

Which of the following drugs should be administered immediately?

  1. Tenecteplase
  2. Rivaroxaban
  3. Dabigatran
  4. Warfarin
  5. Dalteparin (low molecular weight heparin)

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12. A 35 year old obese female who had a surgery for breast cancer 2 weeks ago presents to the Emergency Department with severe pleuritic chest pain, shortness of breath and haemoptysis.

On examination: BP is 80/50 mmHg, heart rate is 130 bpm, she is cyanotic, respiratory rate is 30 and ABG shows Type 1 respiratory failure.

Which of the following drugs should be administered immediately?

  1. Tenecteplase
  2. Rivaroxaban
  3. Dabigatran
  4. Warfarin
  5. Dalteparin (low molecular weight heparin)

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13. A 45 year old female with acute shortness of breath, right-sided pleuritic chest pain and tachycardia is suspected of having a pulmonary embolism. Which is the MOST APPROPRIATE investigation for definitive confirmation of a PE?

  1. Chest x-ray (CXR)
  2. Ventilation perfusion scan (V/Q scan)
  3. D-dimers
  4. Computed tomographic pulmonary angiography (CTPA)
  5. High resolution computed tomography (HRCT)

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13. A 45 year old female with acute shortness of breath, right-sided pleuritic chest pain and tachycardia is suspected of having a pulmonary embolism. Which is the MOST APPROPRIATE investigation for definitive confirmation of a PE?

  1. Chest x-ray (CXR)
  2. Ventilation perfusion scan (V/Q scan)
  3. D-dimers
  4. Computed tomographic pulmonary angiography (CTPA)
  5. High resolution computed tomography (HRCT)

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14. A 40 year old man presents to A&E with chest pain (severity 7/10) and shortness of breath. He reports ‘tearing a muscle’ in his leg while playing football two days earlier. PMH – hypertension. No family history, no recent travel. Non-smoker. Normal BMI.

Which of these test results can EXCLUDE a diagnosis of pulmonary embolism?

  1. Raised D-dimers
  2. Clear CXR
  3. Normal D-dimers
  4. Normal ECG
  5. Normal ECHO

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14. A 40 year old man presents to A&E with chest pain (severity 7/10) and shortness of breath. He reports ‘tearing a muscle’ in his leg while playing football two days earlier. PMH – hypertension. No family history, no recent travel. Non-smoker. Normal BMI.

Which of these test results can EXCLUDE a diagnosis of pulmonary embolism?

  1. Raised D-dimers
  2. Clear CXR
  3. Normal D-dimers
  4. Normal ECG
  5. Normal ECHO

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15. A 65 year old female presents with sudden onset shortness of breath and pleuritic chest pain. She has left-sided leg swelling. She has a history of a right-sided mastectomy for breast cancer five months ago. She has a BMI of 27.

Observations: HR = 102bpm, BP = 110/75 mmHg, SaO2 = 89%, T = 37.7.

What would be the MOST APPROPRIATE management for this patient?

  1. Thrombolysis
  2. Surgical embolectomy
  3. Percutaneous coronary intervention (PCI)
  4. ACE inhibitor
  5. LMWH + warfarin therapy

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15. A 65 year old female presents with sudden onset shortness of breath and pleuritic chest pain. She has left-sided leg swelling. She has a history of a right-sided mastectomy for breast cancer five months ago. She has a BMI of 27.

Observations: HR = 102bpm, BP = 110/75 mmHg, SaO2 = 89%, T = 37.7.

What would be the MOST APPROPRIATE management for this patient?

  1. Thrombolysis
  2. Surgical embolectomy
  3. Percutaneous coronary intervention (PCI)
  4. ACE inhibitor
  5. LMWH + warfarin therapy

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16. A 53 year old man presents to his GP with breathlessness. He denies chest pain but has developed a cough over the past couple of months. He describes two episodes of haemoptysis in the last week. His wife thinks his clothes look bigger on him compared to a month ago.

PMH: 2x pneumonia this year. T2DM.

SX: 25 pack year smoking history. BMI = 35. Consumes 28 units of alcohol per week.

CXR: solitary right lung nodule, adjacent to right main bronchus

What is the MOST LIKELY finding on biopsy?

  1. Adenocarcinoma d. Mesothelioma
  2. Squamous cell carcinoma e. Stomach cancer metastasis
  3. Large cell lung cancer

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16. A 53 year old man presents to his GP with breathlessness. He denies chest pain but has developed a cough over the past couple of months. He describes two episodes of haemoptysis in the last week. His wife thinks his clothes look bigger on him compared to a month ago.

PMH: 2x pneumonia this year. T2DM.

SX: 25 pack year smoking history. BMI = 35. Consumes 28 units of alcohol per week.

CXR: solitary right lung nodule, adjacent to right main bronchus

What is the MOST LIKELY finding on biopsy?

  1. Adenocarcinoma d. Mesothelioma
  2. Squamous cell carcinoma e. Stomach cancer metastasis
  3. Large cell lung cancer

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17. A 55 year old factory worker falls at work. A CXR is performed to exclude rib fracture. Bilateral pleural thickening is seen on CXR. Further history indicates he is very active without any respiratory symptoms. He smokes 20 cigarettes per day. There is no family history of lung disease. He takes no medication.

What is the MOST LIKELY diagnosis?

  1. Asbestosis
  2. Beryllosis
  3. Coal worker’s pneumoconiosis
  4. Silicosis

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17. A 55 year old factory worker falls at work. A CXR is performed to exclude rib fracture. Bilateral pleural thickening is seen on CXR. Further history indicates he is very active without any respiratory symptoms. He smokes 20 cigarettes per day. There is no family history of lung disease. He takes no medication.

What is the MOST LIKELY diagnosis?

  1. Asbestosis
  2. Beryllosis
  3. Coal worker’s pneumoconiosis
  4. Silicosis

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18. A 76 year old retired steelworker has worsening exertional dyspnoea and a chronic cough. He denies chest pain. He has a 45 pack year smoking history but quit aged 50. There is no notable family history. He takes no regular medication. He has noticed that he wheezes when he has an upper respiratory tract infection, and his doctor once prescribed him an inhaler. He is bothered by joint swelling and stiffness.

What is the MOST LIKELY diagnosis?

  1. Asbestosis
  2. Beryllosis
  3. Coal worker’s pneumoconiosis
  4. Silicosis

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18. A 76 year old retired steelworker has worsening exertional dyspnoea and a chronic cough. He denies chest pain. He has a 45 pack year smoking history but quit aged 50. There is no notable family history. He takes no regular medication. He has noticed that he wheezes when he has an upper respiratory tract infection, and his doctor once prescribed him an inhaler. He is bothered by joint swelling and stiffness.

What is the MOST LIKELY diagnosis?

  1. Asbestosis
  2. Beryllosis
  3. Coal worker’s pneumoconiosis
  4. Silicosis

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19. A 38 year old man presents with a fever of 38.5°C, rigors, myalgia, non-productive cough and dyspnoea. On examination he is tachypnoeic, tachycardic and crackles can be heard at the lung bases. He reports that this happens almost every month after he cleans out the cages in which he keeps his racing pigeons.

Which steps should be taken in the management of this patient? (multiple correct answers)

  1. Administer IV hydrocortisone
  2. Administer oxygen
  3. Administer oral prednisolone
  4. Administer oral nintedanib
  5. Advise patient to stay away from the birds

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19. A 38 year old man presents with a fever of 38.5°C, rigors, myalgia, non-productive cough and dyspnoea. On examination he is tachypnoeic, tachycardic and crackles can be heard at the lung bases. He reports that this happens almost every month after he cleans out the cages in which he keeps his racing pigeons.

Which steps should be taken in the management of this patient? (multiple correct answers)

  1. Administer IV hydrocortisone
  2. Administer oxygen
  3. Administer oral prednisolone
  4. Administer oral nintedanib
  5. Advise patient to stay away from the birds

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20. A 56 year old man presents with worsening exertional dyspnoea and a dry cough. He has no other symptoms. He has no notable past medical history. He takes no regular medication and has not been exposed to allergens.

On examination, he has fine crackles audible over his lung bases bilaterally. There are no findings suggestive of fluid overload. His fingers are clubbed.

What would be the MOST LIKELY findings on HRCT?

  1. Bilateral cavitation
  2. Bilateral basal consolidation
  3. Basal and subpleural ground glass appearance
  4. Interlobular thickening
  5. Bilateral pneumothorax

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20. A 56 year old man presents with worsening exertional dyspnoea and a dry cough. He has no other symptoms. He has no notable past medical history. He takes no regular medication and has not been exposed to allergens.

On examination, he has fine crackles audible over his lung bases bilaterally. There are no findings suggestive of fluid overload. His fingers are clubbed.

What would be the MOST LIKELY findings on HRCT?

  1. Bilateral cavitation
  2. Bilateral basal consolidation
  3. Basal and subpleural ground glass appearance
  4. Interlobular thickening
  5. Bilateral pneumothorax

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21. A 1 year old child presents with failure to thrive. The child has more bowel movements per day than other children of the same age, and the stools often look shiny with an unusually foul smell. In addition, the child has been treated with multiple courses of antibiotics for a persistent wet cough. On measurement, the child is small for age, with weight and height below the third percentile.

What is the MOST APPROPRIATE first line investigation?

  1. Dried heel prick test e. Sinus X-ray
  2. Sweat test f. Deep throat swab
  3. Genetic screening

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21. A 1 year old child presents with failure to thrive. The child has more bowel movements per day than other children of the same age, and the stools often look shiny with an unusually foul smell. In addition, the child has been treated with multiple courses of antibiotics for a persistent wet cough. On measurement, the child is small for age, with weight and height below the third percentile.

What is the MOST APPROPRIATE first line investigation?

  1. Dried heel prick test e. Sinus X-ray
  2. Sweat test f. Deep throat swab
  3. Genetic screening

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22. A 50 year old male has recently developed a cough and malaise after returning from a resort holiday in Spain. On examination, he is febrile and has crackles in both lung bases.

What is the MOST LIKELY causative organism?

  1. Bordetella pertussis
  2. Legionella pneumophilia
  3. Klebsiella
  4. Staphylococcus aureus
  5. Coxiella burnetti

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22. A 50 year old male has recently developed a cough and malaise after returning from a resort holiday in Spain. On examination, he is febrile and has crackles in both lung bases.

What is the MOST LIKELY causative organism?

  1. Bordetella pertussis
  2. Legionella pneumophilia
  3. Klebsiella
  4. Staphylococcus aureus
  5. Coxiella burnetti

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23. A 73 year old woman with COPD has been admitted with a worsening cough, fever and rigors. A sputum culture was taken and microscopy revealed gram negative coccobacilli.

What is the MOST LIKELY causative organism?

  1. Legionella pneumophilia
  2. Adenovirus
  3. Mycobacterium tuberculosis
  4. Streptococcus pneumoniae
  5. Haemophilus influenzae

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23. A 73 year old woman with COPD has been admitted with a worsening cough, fever and rigors. A sputum culture was taken and microscopy revealed gram negative coccobacilli.

What is the MOST LIKELY causative organism?

  1. Legionella pneumophilia
  2. Adenovirus
  3. Mycobacterium tuberculosis
  4. Streptococcus pneumoniae
  5. Haemophilus influenzae

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25. A 72 year old male with no known drug allergies has been diagnosed with community acquired pneumonia. Examination and investigation results are as follows: HR 120bpm, RR 35/min, BP 80/50mmHg, urea 7.9mmol/L, no new onset confusion.

What is the MOST APPROPRIATE management?

  1. IV clarithromycin
  2. Oral doxycycline
  3. Oral amoxicillin
  4. IV co-amoxiclav + doxycycline
  5. Oral levofloxacin + doxycycline

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25. A 72 year old male with no known drug allergies has been diagnosed with community acquired pneumonia. Examination and investigation results are as follows: HR 120bpm, RR 35/min, BP 80/50mmHg, urea 7.9mmol/L, no new onset confusion.

What is the MOST APPROPRIATE management?

  1. IV clarithromycin
  2. Oral doxycycline
  3. Oral amoxicillin
  4. IV co-amoxiclav + doxycycline
  5. Oral levofloxacin + doxycycline

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26. A 24 year old male was admitted following a sudden onset of severe dyspnoea during a football game. On examination there is hyperresonance and loss of breath sounds on the right side as well as tracheal deviation to the left side.

What is the MOST APPROPRIATE first line management?

  1. Chest drain insertion to the right 2nd intercostal space, midclavicular line
  2. Chest drain insertion to the left 4/5th intercostal space, midaxillary line
  3. Large bore cannula insertion to the right 2nd intercostal space, midclavicular line
  4. Large bore cannula insertion to the left 2nd intercostal space, midclavicular line
  5. Large bore cannula insertion to the right 4/5th intercostal space, midclavicular line

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26. A 24 year old male was admitted following a sudden onset of severe dyspnoea during a football game. On examination there is hyperresonance and loss of breath sounds on the right side as well as tracheal deviation to the left side.

What is the MOST APPROPRIATE first line management?

  1. Chest drain insertion to the right 2nd intercostal space, midclavicular line
  2. Chest drain insertion to the left 4/5th intercostal space, midaxillary line
  3. Large bore cannula insertion to the right 2nd intercostal space, midclavicular line
  4. Large bore cannula insertion to the left 2nd intercostal space, midclavicular line
  5. Large bore cannula insertion to the right 4/5th intercostal space, midclavicular line

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