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Management for Hypertension

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Pre-operative assessment

  • Etiology of hypertension and point in natural history
    • Rule out secondary hypertension, especially in young hypertensive
    • Age of onset, duration and compliance to treatment

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  • Current treatment
    • identify antihypertensive(s) used
    • Check the adequacy of blood pressure control
      • Measure erect and supine blood pressure
      • Review 4 hourly charting of BP in the ward

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  • Extent of end organ damage
    • CNS system
      • History of CVA, TIA
      • Fundoscopic examination
    • Renal system
      • Renal profile
    • CVS system
      • ECG, CXR
      • Further test like echo, stress test if IHD is suspected/diagnosed

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  • Acceptability for surgery
    • Emergency surgery
      • Depends on urgency of surgery
      • May require IV antihypertensive ( labetolol, hydralazine) to control BP
    • Elective surgery
      • Postpone if diastolic BP > 110 mmHG

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Problems associated with uncontrolled HT

  • Cardiovascular insatiability leading to
    • hypertension during laryngoscopy and intubation
    • Hypotension post induction and before surgery
    • Dysrrhythmias
    • MI
    • Cerebral hemorrhage
    • Hypertensive encephalopathy

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Premedication

  • Patient needs to be adequately sedated to avoid large increases in BP secondary to anxiety ( diazepam night before surgery)
  • Adequate premedication ( benzodiazepine or I/M narcotic analgesics) should be given, the dose and nature of premedication depending on the patient’s general condition and nature of surgery
  • Serve the usual dose of antihypertensive drug on the morning of surgery

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Perioperative management for hypertensive patients

By

Roshnee Kaur Khaira

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  • No particular anaesthetic agent or technique has been found superior!
  • The choice depends on the skill, experience and preference of the anaesthetist.
  • Keep in mind! Problems Associated with Uncontrolled Hypertension, which is Cardiovascular Instability.

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General Anaesthesia

  • Premedication:diazepam, usual dose of anti-hypertensives on morning of surgery.

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Monitoring of patient

  • Mandatory!
  • Continuous monitoring :
  • ECG
  • Blood Pressure: non-invasive or intra-arterial(depends on nature of surgery)
  • Pulse Oximetry
  • Options: Capnography, peripheral nerve stimulator, urine output ,temperature

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  • If patient undergoing a major surgery and with poor left ventricular function?

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  • Central Venous Pressure
  • Pulmonary Artery Catheterisation if required

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Induction

Risk of Cardiovascular Instability

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Leads to

  • Hypertension during laryngoscopy and intubation
  • Hypotension post-induction and before surgery
  • Dysrrhythmias
  • AMI
  • CVA

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  • Use combination of fentanyl with thiopentone or propofol
  • Ketamine is unsuitable: causes hypertension and tachycardia
  • Intravenous anti-hypertensives may be needed if before induction if blood pressure is high despite premedication and morning medication.

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Laryngoscopy and Intubation

  • Obtund Sympathetic responses: options?
  • IV fentanyl 1-2ug/kg, IV Lignocaine 1-1.5 mg/kg, beta-blocker, small dose of thiopentone just before intubation
  • Allow time for the muscle to relax before attempting laryngoscopy and intubation!
  • Best monitored by PNS

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Maintenance

  • Good oxygenation, normocarbia
  • Adequate depth of anaesthesia: narcotic +volatile agent(isoflurane)
  • Choice of muscle relaxants: vecuronium, atracurium (cardiovascularly more stable)
  • Minimise swings of blood pressure perioperatively

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Regional Anesthesia

  • Close blood pressure monitoring
  • If there is hypotension, aggressive early treatment with fluid challenge and ephedrine
  • Make sure regional block works, if pain results from inadequancy can stimulate hypertension and tachycardia
  • Be prepared to convert to general anaesthesia if regional block is not adequate

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Remember

  • Do not supplement inadequate block with sedation
  • Recognise that the patient is hypertensive
  • Examine the extend of end organ damage
  • Optimize treatment and continue medication
  • Minimize swings of blood pressure perioperatively
  • Establish adequate monitoring and early aggressive treatment of hypertension: IV labetalol 5-10 mg, IV hydralazine 5 mg

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Post-op management

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  • Continue close BP monitor in recovery room & early post-op period

  • Post-op hypertension is common

  • Causes:
  • Respiratory abnormalities
  • Pain
  • Volume overload
  • Bladder distention

  • Complications
  • Myocardial ischemia
  • Congestive heart failure
  • Wound hematoma formation
  • Disruption of vascular suture lines

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  • Always correct those readily reversible contributing causes (with analgesic, catheter…)

  • If uncorrected → Give Parenteral anti-hypertensive

  • IV Nicardipine or sublingual nifedipine is usually used particularly if myocardial ischemia or bronchospasm is suspected.

  • patient should be returned to the ward only when the circulation is stable

  • Preoperative HT medication is restarted when patient resumes oral intakes

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Drug

Action

Length of action

Labetalol 10-200mg IV

Alpha & beta blocker

1-4 hours

Propranolol 1-4mg IV

Beta blocker

1-2 hours

Hydralazine 5-20mg IV

Vasodilator

3-6 hours

Nifedipine 10mg sublingual or oral

Calcium channel blocker

2-5 hours

Diazoxide 30mg boluses IV (max 300mg)

Vasodilator

4-12 hours