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Far From the Truth

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Far from the truth

Often presumed that only important because they cause disease, this is far from the truth.

  • Human life would not exist on this planet without the activities of bacteria

  • In addition to the crucial roles in maintaining the life, they also have made life more comfortable e.g. Uses in food production

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New applications for Microorganisms

@ Interferon, insulin, human growth hormone, blood clotting factors, and enzymes that dissolve blood clots and thick mucus in cystic fibrosis patients can be produced by microorganisms.

@ Microorganisms are being developed to produce vaccines against rabies, gonorrhea, herpes, leprosy, malaria and hepatitis.

@ Bacteria can destroy such chemical pollutants as polychlorinated biphenyls (PCBs) and DDT, which contaminate soil and waters. They are also being used to assist the clean up of oil spills.

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New applications for Microorganisms

@ A bacterium is being used to make plants resistant to insect attacks, viral diseases, and frost.

@ Bacteria can synthesize a variety of different compounds that can be used in various ways, such as cellulose used in stereo headset; hydroxybutyric acid, used to make disposable diapers biodegradable; and ethanol, used in gasoline to reduce smog.

@ Bananas genetically engineered by a bacterium may be used as vaccines to prevent certain diarrheal diseases in children

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Important molecules in cells

Macromolecules

  • DNA

  • RNA

  • Proteins

Functions

  • Store genetic information

  • Involved in protein synthesis

  • As enzymes speed up chemical reactions
  • Form part of structure of cell

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Important molecules in cells

Small molecules

  • ATP

  • Coenzymes

  • Amino acids

Functions

  • Storage form of energy

  • Required for enzyme function
  • Synthesize from vitamins

  • Make up proteins

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Prokaryotic and Eukaryotic Cells

Prokaryotic

0.3-2um

1-4(all identical)

No

Unique chemical components

No intracellular organelles

No

No

70S

Eukaryotic

2-20um

>1 (all different)

Yes

Not always present, usually many different components (yeast>citin)

Yes

In some cells

80S

Features of cells

Size (diameter)

Genetic structure

Chromosomal nos.

Nuclear membrane

Cell wall

Cytoplasmic structures

Mitochondria

Chloroplasts

Ribosomes

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Some Cell Type Appear to be Intermediate Between Prokaryotes and Eukaryotes

  • Giardia intestinalis

  • Trichomonas vaginalis

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Prokaryotes can be divided into two major groups

  • Eubacteria (true bacteria): more important in causing disease

  • Archaea (ancient organism): little importance in microbiology related to health and disease

- Grow in environments in which most organisms can not survive