SOMA MAJUMDER�ASSISTANT PROFESSOR�DEPARTMENT OF PHYSIOLOGY�VIJAYGARH JYOTISH RAY COLLEGE
CCF Sem2:�Units 1- 4: Carbohydrates, Lipids, Proteins, DNA
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CLASSIFICATION OF LIPIDS
MONOGLYCERIDE
DIGLYCERIDE
TRIGLYCERIDE
ESTER BOND
1
2
2a
2b
Mono-unsaturated Fatty Acids(MUFA)
Poly-unsaturated Fatty Acids(PUFA)
Non-essential fatty acids
Essential fatty acids
fatty acids
fatty acids
fatty acids
fatty acids
Lauric acid
Myristic acid
Palmitic acid
Stearic acid
Oleic acid
Linoleic acid
Arachidonic acid
Conjugated linoleic acid
Gamma linolenic acid
Linolenic acid
EPA, DHA, ALA
CLASSIFICATION OF PHOSPHOLIPIDS
CHOLESTEROL
POSITIVE SIGNIFICANCE OF CHOLESTEROL
Chargaff’s Rule
Erwin Chargaff, a biochemist, discovered that the number of nitrogenous bases in the DNA was present in equal quantities. The amount of A is equal to T, whereas the amount of C is equal to G.
A=T; C=G
In other words, the DNA of any cell from any organism should have a 1:1 ratio of purine and pyrimidine bases.
DNA Types
There are three different DNA types:
A-DNA: It is a right-handed double helix similar to the B-DNA form. Dehydrated DNA takes an A form that protects the DNA during extreme condition such as desiccation. Protein binding also removes the solvent from DNA and the DNA takes an A form.
B-DNA: This is the most common DNA conformation and is a right-handed helix. Majority of DNA has a B type conformation under normal physiological conditions.
Z-DNA: Z-DNA is a left-handed DNA where the double helix winds to the left in a zig-zag pattern. It was discovered by Andres Wang and Alexander Rich. It is found ahead of the start site of a gene and hence, is believed to play some role in gene regulation.