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06.01 EXCRETORY SYSTEM

Mrs. Jessica Romito

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SUMMARY, OBJECTIVES, AND STANDARDS

Review module

  • 06.01 Excretory system
    • Urine formation

Review assessment

  • 06.01 assessment: flow chart assignment submission

By the end of this class you will

  1. Understand how the brain is involved in urine formation
  2. Know how the liver is involved in urea formation
  3. Understand the function of the nephrons and glomerulus
  4. Successfully complete assessment submission for 06.01

STANDARDSSC.912.L.14.47: Describe the physiology of urine formation by the kidney.

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URINARY FUNCTION

Urine made by the kidneys

Drains to

Bladder for temporary storage

Anything less than 800mL

600-800mL for an adult

Reaches capacity at/urge to urinate/unconscious control

Conscious control

More on the capacity of the bladder with references

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THE KIDNEYS

FUNCTIONS:

  1. hormone secretion
  2. blood pressure regulation

MAIN FUNCTIONS:

  1. filtering the blood
  2. removing urea from the body.
    • Urea is a nitrogen compound made from the break-down of certain proteins.
    • It is toxic to our body, so it is quickly eliminated through our urinary system.

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NEGATIVE FEEDBACK LOOP

The regulation of water content takes place in the kidneys and is under the control of a hormone called ADH, antidiuretic hormone. Like most homeostatic mechanisms, the maintenance of water balance involves negative feedback.

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URINE FORMATION

When the body is short of water, the HYPOTHALAMUS responds in two ways.

  1. STIMULATES the thirst centers in the brain.
  2. Stimulates the PITUITARY GLAND to secrete Antidiuretic Hormone, ADH, into the blood, where it's carried to the kidneys. 

It's the kidneys' job to FILTER the blood and REGULATE its water content.

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OSMOREGULATION

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URINE FORMATION

It's the kidneys' job to FILTER the blood and REGULATE its water content.

URINE is a watery fluid that's produced in the kidneys.

    • It's our body's way of removing soluble toxins that have accumulated.
    • The body needs to remove them because if they were allowed to build up, they would POISON the tissues. 

Click here for a nice review of the anatomic structures for urine formation

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URINE FORMATION

The urine trickles down the URETERS or tubes, connecting the kidneys to the bladder.

As more urine collects, the bladder expands.

    • And at a certain point, it's automatically emptied. 

The major waste product in urine is UREA.

It is formed in the liver from the breakdown of PROTEINS, which is not required by the body. 

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URINE FORMATION

The urea is transported in the blood to the kidneys.

Here it’s REMOVED and mixed with water and other substances removed from the blood to form urine. 

There are millions of NEPHRONS in the kidney.

They are responsible for removing urea from the blood. 

They are cleaning structures.

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URINE FORMATION

Blood entering the kidney

Blood leaving the kidney

High in urea

No urea

High in oxygen

Low in oxygen (due to cell respiration)

No carbon dioxide

High in carbon dioxide (due to cell respiration)

Glucose levels high

Glucose present but lowering in concentration. (due to cell respiration)

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URINE FORMATION

Blood reaches the GLOMERULUS, where the narrow vessels create an area of relatively high pressure.

This forces the fluid part of the blood through the walls of the GLOMERULUS capillaries.

Blood cells and proteins are too large to pass through and remain in the blood, but the fluid passes through. 

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URINE FORMATION

The filtered fluid, or filtrate, trickles along the RENAL TUBULE, where much of the water, glucose, and salts are reabsorbed, ensuring the blood maintains its correct composition.

The toxic urea is left in the fluid. 

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URINE FORMATION

The remaining fluid then trickles into the collecting ducts and finally into the ureters.

Now called urine, it passes down the ureters and drips into the BLADDER.

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ASSIGNMENT 06.01

Use the Urine Formation worksheet from page 2 of the module (went over the answers in this class).

Be able to fill in this table:

Component

Do you know…

Function

ADH

Location?

Hypothalamus

Location?

Liver

Structure?

Nephrons

Structure?

Pituitary

Location?

Urea

Location?

Renal Tubule

Structure?

Glomerulus

Structure?

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ASSIGNMENT 06.01

ASSESSMENT

Create a flow chart to represent and describe the process of urine formation in the kidneys. You can use any flow chart format that you wish but you must include the components below:

  • ADH
  • Hypothalamus

  • Liver
  • Nephrons

  • Pituitary
  • Urea

  • Renal tubule
  • Glomerulus

Keep in mind: the process of urine formation is NOT linear because there are multiple components involved, ie the brain, liver, and kidneys

This will affect your flow chart design.

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Contact Information

Mrs. Jessica Romito

Phone Number: +1 (301) 485-9114

(text/call/WhatsApp)

Email: jromito@laurelsprings.com

Mrs. Romito's iClassroom

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