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PrEP

PREGNANT & BREASTFEEDING PEOPLE

know the facts

This curvy font is called “Autumn Wind” – if you can’t use this, use any other curvy font.

PrEP is a safe HIV prevention method that HIV-negative people can use to prevent HIV:

  • If you choose oral PrEP, the pills need to be taken daily to help prevent HIV.
  • If you choose injectable PrEP (CAB-LA or LEN) you need to return to the clinic for your follow-up injections either every 2 months (CAB-LA) or every 6 months (LEN).
  • PrEP has been shown to be very effective, oral PrEP reduces the chance of HIV infection by more than 90% and injectable PrEP, by more than 96%.
  • PrEP is only for people who are HIV negative.

PrEP during pregnancy:

  • If you are pregnant and have sex without a condom, your chances of being infected with HIV is much higher.
  • If you test positive for HIV, you will receive ARV treatment - this prevents your baby from getting HIV.
  • Using PrEP before, during and after pregnancy �can prevent HIV.

What is the difference between PrEP, PEP, and ART?

PrEP is when ARVs are taken before exposure to HIV, to prevent getting HIV.

PEP is when ARVs are taken after exposure to HIV, to prevent HIV (within 72 hours and taken for 28 days only).

ART is when ARVs are used to treat a person living with HIV, and is taken lifelong.

All three use

antiretrovirals

in different

combinations for different purposes:

Version 2026: This material has been adapted based on resources developed by Wits RHI in support of the National Department of Health in South Africa. This activity is made possible by the generous support of Unitaid.

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Starting PrEP...

When you start a PrEP method, this is what you can expect:

  • A health check, including HIV and STI screening, supported by counselling
  • You will start the PrEP method of your choice
  • Your healthcare provider will explain how soon your method will start working — use a condom or avoid sex while protection builds

When protection starts:

  • Oral PrEP starts working after 7 days of daily use
  • The CAB-LA injection starts working 7 days after the first injection
  • Len is given as two injections on Day 1, together with two tablets, and then two more tablets on Day 2. It starts working soon after you take the tablets on Day 2
  • Continue using your chosen PrEP method correctly for as long as you need protection
  • Your healthcare provider will explain when to return for your follow-up visit
  • At each follow-up visit, you will receive a health check, including HIV and STI screening, supported by counselling

Pre

(before)

Exposure

(coming into contact with HIV)

Prophylaxis

(a medicine to prevent infection)

Where can I get PrEP...

Oral PrEP is available in most public clinics. CAB-LA and LEN is available in some public clinics and community sites. For more information, visit: [insert website / contact details]

Don’t forget your antenatal care visits!

PrEP is one of many options for HIV prevention. You can also try:

  • Condoms
  • Counselling
  • PEP
  • Treatment for STIs
  • Male medical circumcision
  • ART for partners living with HIV
  • Regular HIV testing for you and your partner

Decide if PrEP is for you:

  • PrEP is safe for you and your unborn baby and/or child, �while you are pregnant and/or breastfeeding.
  • PrEP can protect you from HIV.
  • You can use PrEP without anybody else knowing.
  • You can take PrEP if you and your partner who is living with HIV want to have a baby.
  • You can continue using PrEP even when you are breastfeeding.

You can take care of yourself and your baby, choose �PrEP!