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Research Data Alliance-Oracle for Research (RDA-OfR)

Creating a Multi-omics Metadata Schema Standard Reporting Matrix WG

Working Group Kick-off meeting

Wednesday, 29 November 2023

15:00 - 16:00 UTC

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A few logistics

  • Background: About the Working Group
  • Shared Google folder for the WG meetings & outputs
  • Docs and deliverables only editable by members
  • How to participate during this meeting:
    • 📝 Sign in & take notes in our collaborative Google doc
    • 📹 Discussions recorded for internal use
    • 🖐 Raise hand & unmute
    • 💬 Add to the chat
  • Take a moment to read our guiding principles and how to report a breach at the top of the Google doc.
  • RECORD!

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Today’s meeting agenda

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Time (UTC)

Meeting agenda item

Lead

15:00 - 15:10

Welcome and housekeeping

  • Introduction to the RDA and OfR partnership
  • Introduction to the facilitator and co-chairs
  • Role of the facilitator

Connie Clare

15:10 - 15:20

Introduction to the WG:

  • Background
  • Aims/objectives
  • Deliverables
  • Milestones & proposed timeline

David Molik

15:20 - 15:35

Overview of -Omics resources used as training materials

Lindsey Anderson

15:35 - 15:40

Getting to know WG members: Menti

Lindsey Anderson

15:40 - 15:55

Q&A/Discussion

Tim Van Den Bossche

15:55 - 16:00

Closing remarks and next steps

Tim Van Den Bossche

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Vision

Researchers and innovators openly share and re-use data across technologies, disciplines, and countries to address the grand challenges of society.

Mission

RDA builds the social and technical bridges that enable open sharing and re-use of data.

Guiding principles

  • Openness
  • Consensus
  • Inclusivity
  • Harmonisation
  • Community-driven
  • Non-profit & technology neutral

The RDA Community

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Global

Community-driven

13,900+

international experts

80

organisational & affiliate members

35

regional �networks

150+

countries

75+

flagship

recommendations & outputs

100+

community groups

Consensus based

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Collaboration with Oracle for Research

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🧬 Read more

Public-private partnership model

    • Two WGs facilitated by the RDA (12 months)
    • Outputs owned by the RDA community
    • Supported by Oracle for Research

RDA’s strategic plan 2024-2028

  • Professional facilitation to support global volunteer effort
  • Accelerate data-driven developments

Categorisation schema of types of research tools by research data lifecycle.

Creating a metadata schema standard reporting matrix.

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Meet the Co-chairs & Facilitator

Connie Clare, PhD

Community Development Manager

Research Data Alliance

WG Facilitator

connie.clare@rda-foundation.org

David Molik, PhD

Computational Biologist

USDA ARS - ABADRU

WG Co-chair

david.molik@usda.gov

Lindsey Anderson

Computational Chemical Biologist

Pacific Northwest National Laboratory/

FAIRsharing Omics Champion

WG Co-chair

Lindsey.Anderson@pnnl.gov

Tim Van Den Bossche, PhD

Bioinformatics researcher

Ghent University

WG Co-chair

tim.vandenbossche@ugent.be

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Role of the facilitator

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  • Providing assistance and support for WG co-chairs and members:
    • Setting up Zoom meetings and sending calendar invitations.
    • Creating slide templates and collaborative notes documents.
    • Chairing and note-taking during WG meetings.
    • Maintaining WG documentation in Google folder.
    • Monitoring progress and adherence to WG timelines, namely delivery of outputs/deliverables.
  • Serving as a liaison between WG (co-chairs & members) and:
    • RDA governance bodies (e.g., TAB and Secretariat)
    • Oracle for Research colleagues
  • Creation and dissemination of communications via:
    • Emails/mailing lists
    • News items
    • Progress reports
    • Social media

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Background and Introduction

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Introduction to the Working Group

  • Multi-omics data integration combines diverse biological data types through high-throughput technologies to comprehensively understand molecular interactions in living organisms
  • Yet challenges persist in managing and sharing the increasing volume of generated datasets
  • This working group aims to solve some of these challenges

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Problem Statement

“[There exists a] vast array of fragmented experimental metadata and data formats generated across the different Omics domains which it difficult to manage and integrate multi-omics data prior to downstream analyses.”

  • Standards reporting in multi-omics metadata is lacking
  • Lacking of reporting is causing data formatting problems
    • Interoperability
    • Downstream analysis

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Aims & Objectives Statement

  • Guide data producers through the vast array of fragmented experimental metadata and data formats
    • By leveraging preexisting
      • Omics domain metadata standards,
      • Ontologies,
      • Reporting guidelines,
  • “this working group will advance current siloed community harmonisation efforts with much needed cross-disciplinary diversity for creating more sustainable standard reporting guidelines fully representative of various data types and computational formats.”

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WG Deliverables Overview

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Timeline

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Month/Year

Preliminary WG Activities

November 2023

  • 1st WG meeting (WG kick-off meeting & member consultation, training material overview)

December 2023

  • 2nd WG meeting (i. Presentation of WG aims, objectives, deliverables and timeline. ii. Allocation of task groups by domain expertise)

January 2024

  • 3rd WG meeting (Landscape review)

February 2024

  • 4th WG meeting (Landscape review)

March 2024

  • 5th WG meeting (Landscape review)
  • Definition of WG recommendations & outputs structure

April 2024

  • 6th WG meeting (finalise landscape review: creation of Omics Domain collection in FAIRSharing efforts from task groups)

May 2024

  • 7th WG meeting (crosswalk)

June 2024

  • 8th WG meeting (crosswalk)

July 2024

  • 9th WG meeting (finalise crosswalk and start collecting use cases). This activity will help to identify the core metadata schema reporting matrix and invitation of use-case example representatives providing feedback on how well their resource captures elements from the matrix for more than one omics domain.

August 2024

  • 10th WG meeting (metadata schema standard reporting matrix and use cases)

September 2024

  • 11th WG meeting (metadata schema standard reporting matrix and use cases)

October 2024

  • 12th WG meeting (metadata schema standard reporting matrix)
  • Final WG Recommendation Community review

November 2024

  • Final WG Recommendation Endorsement (Council) & Press campaign

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Educational Materials for Landscape Review

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FAIRsharing Community Standards

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Omics Domain Standard Examples

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FAIRsharing Omics Database Examples

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FAIRsharing Community Collections

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Gathering Omics Record Resources

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Getting to know our WG members

Go to www.menti.com and enter code: 7594 6932 or scan the QR code with your mobile device camera (survey expires 2023-12-12)

Results will be available after the kick-off meeting and will be made accessible from the WG share folder.

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Open Discussion (10 min) & Q&A

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Closing remarks and next steps

Thank you all for joining and for your active participation!

  • Recruitment of members from the Global South - Can you help?
  • Next WG meeting: Wednesday 13 December, 15:00 UTC
  • All documentation on WG webpage
  • Any questions or comments, please contact Co-chairs or facilitator
  • JOIN THE WORKING GROUP! Click the join group button

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