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Food Allergy Storyline Unit

Lesson 6: How can genetic variation lead to a milk allergy?

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What did we do in the last class?

At the end of lesson 5, we constructed an explanation for congenital lactose intolerance.

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Experience the Phenomenon

Work together to develop a consensus model.

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Experience the Phenomenon

Using your previous models, look for differences between the receptors for the individual who does not have an allergy and the individual who does.

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Investigate the Phenomenon

To figure out more about genes and allergies, let’s analyze data from a study about the genes of people with milk allergies.

We will use this data and ideas developed in Lessons 3–5 to revise their allergy models from Day 2.

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4. Point out that many students had questions about how genes connect to allergies. To answer those questions, they will analyze data from a study about the genes of people with milk allergies. Students will use this data and ideas developed in Lessons 3–5 to revise their allergy models from Day 2.�

Distribute and project the milk allergies data. Let students know that the data comes from a study of 2,197 children in the United States, published in 2015.
Let students know that milk allergies are not as well understood as lactose intolerance or other food allergies, such as peanut allergies. Scientists are still trying to answer many questions about allergies. This is information about one gene, but many other factors are involved.
Students discuss the data with a partner and consider how the genetic data could connect to milk allergies.
Circulate and consider using one of the Suggested Prompts if students are having difficulty getting started.

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Investigate the Phenomenon

Make observations of other group models.

Be prepared to discuss your observations with the class.

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Explain the Phenomenon

Evaluate unanswered questions from our DQB.

Brainstorm ideas for potential solutions.

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Explain the Phenomenon

Research potential treatments for food allergies.

Before reading your assigned article, we will watch a short video.

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Explain the Phenomenon

FARE: Advancing a Cure for Food Allergies video

FARE’s mission is to improve the quality of life and the health of individuals with food allergies, and to provide them hope through the promise of new treatments.

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Explain the Phenomenon

Update the DQB.

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What’s Next?

Consider what you would like to investigate further.