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Public Health, Epidemiology,�& Models

MMED 2024�Carl Pearson

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Goals

  • Define Public Health, Epidemiology, & Models
  • Discuss how they relate
  • Set up future sessions

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Practical!

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Modeling

Is:

  • approximation / prediction
  • scientific representation of a phenomenon to study it
  • mathematical description of a system

Isn’t:

  • exact representation
  • data collection
  • only mathematical representation of a phenomenon

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Public Health

Is:

  • total well-being of whole population
  • citizens activity to control spread of infectious disease
  • science of prevention of diseases, promoting health

Isn’t:

  • everyone having access to healthy lifestyle
  • the story of individuals health
  • for animals

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Epidemiology

Is:

  • study of transmission infectious diseases
  • involves modeling
  • helps curb spread of diseases

Isn’t:

  • which vaccine is used for treatment
  • study of chronic diseases
  • exclusive to infectious disease

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Modeling

Is:

  • Formal / rules-based description
  • Possible to use / implement as tool(s)
  • An abstraction / generalization across circumstances

Isn’t:

  • True or inclusive of all plausible phenomena
  • Necessarily a series of equations
  • An experiment

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Public Health

Is:

  • Focused on outcomes for whole group(s)
  • Conscious of tradeoffs / competing concerns
  • About what to *do*

Isn’t:

  • Individual diagnosis of a particular patient
  • “Do no harm” or generally about an easy “right way”
  • Only restricted to medical interventions

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Epidemiology

Is:

  • Creation, collection, & curation of data
  • about distribution & determinants of health-related states / events in populations
  • To identify causal factors of disease & non-disease

Isn’t:

  • Medicine, e.g. not treatment of patients
  • (Health) policy making or control activities
  • Expert in health-dependent states / measures / &c

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How are they distinct?

How do they fit together?

Why should we care?

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Public�Health

Epidemiology

Modeling

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An example:

COVID-19

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Public�Health

Epidemiology

Modeling

How will Y rate of vaccine coverage, started at time t, impact cumulative incidence?

Assuming branching process distribution / timing, how long until X cases?

Given detection rate, how many infections when first case notified?

If response reduces R0 by Y%, what will be peak incidence?

If we allocate vaccine this vs that way, which minimize deaths?

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Epidemiology

Modeling

Public�Health

Is this new pathogen a threat?

How much should / can we spend?

Who do we prioritize for care / vaccine?

Do we need to increase healthcare system capacity? Can we?

Should we change vaccine approval policy?

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Public�Health

Modeling

Epidemiology

How does transmission happen?

What is time course of infection / disease?

How accurately does testing perform?

How well does a vaccine work at preventing infection? Disease? Death?

What is the mortality rate? The asymptomatic rate?

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Public�Health

Epidemiology

Modeling

If we allocate vaccine this vs that way, which minimize deaths?

Who do we prioritize for care / vaccine?

How well does a vaccine work at preventing infection? Disease? Death?

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Tension!

  • There’s a finite amount of vaccine - who gets it first?*
  • Highest risk of death? Those Necessary to re-open economic activity?
  • Epidemiology can tell us e.g. disease risk (after some time), modeling project impact (w/ data & assumptions), but public health has to integrate many factors

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Summary

  • Public Health, Epidemiology, & Models - different definitions, for different activities, serving different ends
  • Overlapping elements – typically need each other to “do well” – but worthwhile to remember distinctions
  • MMED aim: work on the intersection of the categories!

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Questions?

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This presentation is made available through a Creative Commons Attribution-Noncommercial license. Details of the license and permitted uses are available at� http://creativecommons.org/licenses/by/3.0/

Attribution:

Clinic on the Meaningful Modeling of Epidemiological Data

© 2014-2023 International Clinics on Infectious Disease Dynamics and Data