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Dr Ruth Laibon Masha, PhD, EBS�Chief Executive Officer��National Syndemic Diseases Control Council�Kenya

From Boutique to systemic and sustainable scale up:

The case of HIV prevention

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The HIV Response …

2

  • HIV related deaths
  • Suppression of Viral Load

  • New Infection

  • Invest in care and treatment
  • Address Treatment Interruption
  • Stop stigma
  • Invest in effective HIV Prevention interventions implemented to scale

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The Programmes within HIV prevention response operate in siloes

The prevention programme predominantly focuses on biomedical solutions

The prevention programme is highly dependent on donors.

The prevention programme needs innovation and scale up

01

02

03

04

Challenges

Systemic challenges

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Translating the thinking differently into doing differently..

  1. Clear goals for Treatment, but none for prevention
  2. Adopting a ‘one size fits all’
  3. Inefficient deliveries
  4. Decision is not data-based
  5. Shared responsibility and accountability undefined
  6. HIV response still heavily bio-medical
  7. Sub-national levels of investment case

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Thinking differently…

From national to County clusters

High, Medium, Low incidence cluster

Timely data on granularity of epidemics

Timely incidence surveillance

From interventions to populations

By age group

By priority populations

By bridging populations

From biomedical only to combination prevention

targeted packages at scale

faster research to policy translation

coordinated R&D for HIV prevention

From health to HIV prevention as everyone's business

Leverage political leadership

Leverage social movements

Legal and structural reforms

Who needs HIV Prevention? (populations)

What do they need?

(risk, perceptions)

What is available?

(evidence-based interventions)

How will it be delivered?

(packaging, settings, delivery)

What will it cost?

(cost, effectiveness)

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People Living with HIV in Kenya (2013)

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Differentiation of sub-populations (2013)

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Sub-national level heterogenous (2013)

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Data for decision making

  • A data feedback model for accountability and responsibility

  • Focus on outcomes

  • Improved surveillance

  • Research for local solutions

  • Modeling for decision making

  • Research uptake

  • New prevention technologies

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Rationale …..

  • To utilise existing resources to implement the right combination of intervention to targeted populations in most at risk population groups and geographical areas to achieve maximum impact.
  • Tailor Combination Prevention for the 47 Counties based on the nature of the epidemic in their county

Saves lives

Saves Money

By 2030

1,149,000 new HIV infections &

761,000 AIDS-related deaths

11,000 children deaths

will be averted at no extra cost

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New HIV infections reduced by 78.2% in the last decade from 101, 448 in 2013 to 22,154 in 2022

2013

2015

2018

2019

2020

2021

52,800

41,416

34,540

101,448

77,647

32,027

2022

22,154

Source: HIV Estimates 2023

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HIV situation in 2022

1,377,784

Kenyans living with HIV in 2023

67,869

Children (0-14 years) living with HIV in 2023

2.6%

5.3%

National HIV prevalence is 3.7%

18,473

AIDS-related deaths 2022

Country

No. of PLHIV

Kisumu

128,091

Nairobi (County)

124,609

Homa Bay

120,600

Siaya

96,297

Migori

76,053

Nakuru

57,635

Mombasa

50,656

Kakamega

48,733

Kiambu

45,917

Kisii

42, 210

In 2022

57%

of people living with HIV were in

10

Counties

18.3%

HIV PREVALENCE AMONG KEY POPULATIONS

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22,154

New HIV Infections

4,474

12,558

5,122

Children aged 0-14

Women

Men

Source: Kenya HIV Estimates 2023

Kenya Demographic Health Survey 2022

Kenya Health Information Systems 2023

New HIV infections

41%

Adult new HIV infection occur among Adolescents and Young People aged 15-24 years

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What have we learnt?

  • County-level capacity for designing, implementing, and monitoring effective prevention programs at scale is sub-optimal.
  • Existing interventions are often generic and fail to consider the diversity in epidemic typology. The analysis of the size and location of priority populations for planning population-based prevention interventions is incomplete.
  • Prevention programs operate independently rather than as part of a cohesive continuum, hindering the monitoring of individuals across the spectrum.
  • Various determinants of health, both at the individual and broader structural levels, pose challenges for HIV prevention. Lack of coordination and collaboration results in duplicated efforts and negatively impacts healthcare costs.
  • Interventions predominantly focus on biomedical approaches, with minimal emphasis on behavioral and structural strategies that are community-led.
  • Analytical capacity and data utilization at both national and county levels are insufficient, leading to poor feedback mechanisms to relevant stakeholders.
  • There is a higher dependence on donor funding, and HIV prevention receives low priority in planning and budgeting.

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Strategy 1: Apply a precision and differentiated HIV prevention approach based on incidence, prevalence, and changing epidemic typology in the geography ��

“Concentrated” epidemic in

22 counties

“Generalizing” epidemic in

4 counties

“Mixed” epidemic in

21 counties

Concentrated

Key Populations

Mixed

Adolescent and young people

Key Populations

Pregnant and lactating women and children

Pregnant and lactating women and children

PLHIV

Generalizing

Vulnerable populations and other networks

Adolescent and young people

Key Populations

Pregnant and lactating women and children

PLHIV

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Establishment and application of Baseline data (IBBS 2011)

2011-2012

Development of National Policies, guidelines and standard operating procedures (HIV prevention Revolution Roadmap)

2013-2015

Adoptation and Implementation of combination prevention interventions *Behavioral; Biomedical; Structural)

2016-2018

Start

The National Key Population program was established

2009-2010

Key Population programme scale up and quality assurance

2018-2020

Epidemic Appraisal to guide counties response

2021-2023

Sustain effective interventions for key populations

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Strategy 2: Develop tools to measure quality, coverage and impact of interventions to address coverage and utilization gap�

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���Strategy 3: Strengthen and expand community-led HIV prevention services���

  • Promote community-led initiatives to empower local decision-making in HIV prevention and service delivery.
  • Establish national and subnational targets for expanding the involvement of community-led organizations accountability forums
  • Advocate for funding (domestic and external) for community led organisations engaged in HIV prevention
  • Create a supportive environment for non-governmental organizations to operate, offer services through enhanced technical and managerial capabilities.

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Strategy 4 ; Integrate HIV prevention by strengthening health systems and leveraging multiple sectors

  • Integration of HIV prevention within universal health coverage discourse to expand these achievements beyond addressing a single disease.
  • Intra and inter-sectoral integration between

a) HIV prevention programs, including PrEP, VMMC, condom promotion, and initiatives targeting specific sub-populations.

b) HIV prevention with other health sector programs, including tuberculosis control, viral hepatitis prevention and care, reproductive, maternal and child health, adolescent health, family planning, and sexually transmitted infection control.

c) With other non-health sectors platforms such as education, gender equity, housing and social protection.

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Strategy 5: Improve utilization of programme data

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Strategy 5: Invest and prepare for adoption of HIV prevention choices and technology

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1980’s

2030

Scheckter M, 2002

?

Early population-level

successes (late 1980s)

Behavior change (Uganda)

100% Condom use (Thailand)

STI Treatment

Grosskurth, Lancet 2000,

(likely to work mainly in HIV epidemics /sub-populations with high bacterial STIs)

Male & female condoms

Male circumcision

Auvert, PloS Med 2005; Bailey, Lancet 2007; Gray, Lancet 2007

Coates, Lancet 2000

Sweat, Lancet 2011

(effects mostly for persons who test HIV positive and couples)

HIV testing & counselling

Post-exposure prophylaxis

Cohen, NEJM, 2011; Donnell, Lancet 2010; Tanser, Science 2013

Treatment as prevention

Oral �pre-exposure prophylaxis

Grant, NEJM 2010 (MSM)

Baeten, NEJM 2012 (Couples)

Paxton, NEJM 2012 (Heterosex.); Choopanya, Lancet 2013 (PWID)

�Ongoing …..

Carey, 1992

Weller, Cochrane DBS 2002

Hanenberg, Lancet 1994

Stoneburner, Science 2004

Harm reduction

Ljungberg, AIDS 1996

Des Jarlais, Lancet 1996 Hurley, Lancet 1997

Preventing transmission and acquisition of HIV: A timeline

1990’s

2000’s

2020’s

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Leverage on development synergies …Interventions with proven Impact

– Economic Empowerment of women and girls (IMAGE studies; cash transfer programmes)

– Secondary education for girls and young women

– Community empowerment (sex workers in India)

– Harm reduction policies

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Going back to basics

New Kid on the block

  • The story of condoms- effective, cost effective but…challenges with commodity security, demand, access, Utilization and disposal and most important monitoring, tracking and evaluation

  • Countries should define priorities

    • Instititutionalize prevention :
      • Social contracting or other mechanisms for funding for communities
      • Development and Strengthening of systems to demonstrate community contribution

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Strategy 6 : Prioritize prevention funding…..

An analysis of the AIDS Spending Categories (ASC) according to the KNASA report 2022 .

Care and Treatment -51 %

HIV Testing -12 %

Prevention -9%

Social protection and economic support 7%

Research (0.1%).

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Prevention progress not fast enough…strategic investments still required….

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HIV prevention must be prioritized in funding transitions and sustainability agendas

  • Costing for HIV prevention is a key priority

Source: KNASA 2022

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